JP2024534575A5 - - Google Patents

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Publication number
JP2024534575A5
JP2024534575A5 JP2024518410A JP2024518410A JP2024534575A5 JP 2024534575 A5 JP2024534575 A5 JP 2024534575A5 JP 2024518410 A JP2024518410 A JP 2024518410A JP 2024518410 A JP2024518410 A JP 2024518410A JP 2024534575 A5 JP2024534575 A5 JP 2024534575A5
Authority
JP
Japan
Application number
JP2024518410A
Other languages
Japanese (ja)
Other versions
JP2024534575A (ja
JPWO2023049299A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/044453 external-priority patent/WO2023049299A2/en
Publication of JP2024534575A publication Critical patent/JP2024534575A/ja
Priority to JP2025171713A priority Critical patent/JP2026012737A/ja
Publication of JPWO2023049299A5 publication Critical patent/JPWO2023049299A5/ja
Publication of JP2024534575A5 publication Critical patent/JP2024534575A5/ja
Pending legal-status Critical Current

Links

JP2024518410A 2021-09-22 2022-09-22 Pcsk9又はangptl3の遺伝子編集、並びに疾患の治療のためにそれらを使用する組成物及び方法 Pending JP2024534575A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025171713A JP2026012737A (ja) 2021-09-22 2025-10-10 Pcsk9又はangptl3の遺伝子編集、並びに疾患の治療のためにそれらを使用する組成物及び方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163247236P 2021-09-22 2021-09-22
US63/247,236 2021-09-22
US202163255333P 2021-10-13 2021-10-13
US63/255,333 2021-10-13
US202263389679P 2022-07-15 2022-07-15
US63/389,679 2022-07-15
PCT/US2022/044453 WO2023049299A2 (en) 2021-09-22 2022-09-22 Gene editing of pcsk9 or angptl3 and compositions and methods of using same for treatment of disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025171713A Division JP2026012737A (ja) 2021-09-22 2025-10-10 Pcsk9又はangptl3の遺伝子編集、並びに疾患の治療のためにそれらを使用する組成物及び方法

Publications (3)

Publication Number Publication Date
JP2024534575A JP2024534575A (ja) 2024-09-20
JPWO2023049299A5 JPWO2023049299A5 (https=) 2025-10-21
JP2024534575A5 true JP2024534575A5 (https=) 2025-10-21

Family

ID=85721146

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2024518410A Pending JP2024534575A (ja) 2021-09-22 2022-09-22 Pcsk9又はangptl3の遺伝子編集、並びに疾患の治療のためにそれらを使用する組成物及び方法
JP2025171713A Pending JP2026012737A (ja) 2021-09-22 2025-10-10 Pcsk9又はangptl3の遺伝子編集、並びに疾患の治療のためにそれらを使用する組成物及び方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025171713A Pending JP2026012737A (ja) 2021-09-22 2025-10-10 Pcsk9又はangptl3の遺伝子編集、並びに疾患の治療のためにそれらを使用する組成物及び方法

Country Status (10)

Country Link
US (1) US20240390520A1 (https=)
EP (1) EP4405470A2 (https=)
JP (2) JP2024534575A (https=)
KR (2) KR20250160515A (https=)
AU (1) AU2022349449A1 (https=)
CA (1) CA3232742A1 (https=)
GB (3) GB2700667A (https=)
IL (1) IL311607A (https=)
MX (1) MX2024003570A (https=)
WO (1) WO2023049299A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4545544A3 (en) * 2015-06-29 2025-10-08 Ionis Pharmaceuticals, Inc. Modified crispr rna and modified single crispr rna and uses thereof
CN121555430A (zh) 2018-05-11 2026-02-24 比姆医疗股份有限公司 使用可编程碱基编辑器系统取代病原性氨基酸的方法
KR20210055733A (ko) 2018-09-07 2021-05-17 빔 테라퓨틱스, 인크. 핵염기 편집 시스템을 전달하기 위한 조성물 및 방법
EP3850088A4 (en) 2018-09-07 2023-07-19 Beam Therapeutics, Inc. Compositions and methods for improving base editing
WO2020168122A1 (en) 2019-02-13 2020-08-20 Beam Therapeutics Inc. Modified immune cells having adenosine deaminase base editors for modifying a nucleobase in a target sequence
EP4034138A4 (en) 2019-09-27 2024-07-31 Beam Therapeutics, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS
AU2021347359A1 (en) 2020-09-25 2023-05-18 Beam Therapeutics Inc. Fratricide resistant modified immune cells and methods of using the same
WO2023240076A1 (en) 2022-06-07 2023-12-14 Scribe Therapeutics Inc. Compositions and methods for the targeting of pcsk9
WO2025137465A1 (en) * 2023-12-21 2025-06-26 Beam Therapeutics Inc. Base editors with modified editing windows
WO2025167914A1 (zh) * 2024-02-07 2025-08-14 益杰立科新加坡有限公司 通过表观编辑多靶点治疗疾病的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8691750B2 (en) * 2011-05-17 2014-04-08 Axolabs Gmbh Lipids and compositions for intracellular delivery of biologically active compounds
EP3250691B9 (en) * 2015-01-28 2023-08-02 Caribou Biosciences, Inc. Crispr hybrid dna/rna polynucleotides and methods of use
JP7109784B2 (ja) * 2015-10-23 2022-08-01 プレジデント アンド フェローズ オブ ハーバード カレッジ 遺伝子編集のための進化したCas9蛋白質

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