JP2024534541A5 - - Google Patents

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Publication number
JP2024534541A5
JP2024534541A5 JP2024518109A JP2024518109A JP2024534541A5 JP 2024534541 A5 JP2024534541 A5 JP 2024534541A5 JP 2024518109 A JP2024518109 A JP 2024518109A JP 2024518109 A JP2024518109 A JP 2024518109A JP 2024534541 A5 JP2024534541 A5 JP 2024534541A5
Authority
JP
Japan
Application number
JP2024518109A
Other languages
Japanese (ja)
Other versions
JP2024534541A (ja
JPWO2023047127A5 (https=
Filing date
Publication date
Priority claimed from GBGB2113602.3A external-priority patent/GB202113602D0/en
Priority claimed from GBGB2206360.6A external-priority patent/GB202206360D0/en
Application filed filed Critical
Priority claimed from PCT/GB2022/052415 external-priority patent/WO2023047127A1/en
Publication of JP2024534541A publication Critical patent/JP2024534541A/ja
Publication of JP2024534541A5 publication Critical patent/JP2024534541A5/ja
Publication of JPWO2023047127A5 publication Critical patent/JPWO2023047127A5/ja
Pending legal-status Critical Current

Links

JP2024518109A 2021-09-23 2022-09-23 被験体の眼瞼筋を冒す障害の治療における使用のための改変BoNT/A Pending JP2024534541A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB2113602.3A GB202113602D0 (en) 2021-09-23 2021-09-23 Treatment of a disorder affecting an eyelid muscle of a subject
GB2113602.3 2021-09-23
GBGB2206360.6A GB202206360D0 (en) 2022-04-29 2022-04-29 Treatment of a disorder affecting an eyelid muscle of a subject
GB2206360.6 2022-04-29
PCT/GB2022/052415 WO2023047127A1 (en) 2021-09-23 2022-09-23 Modified bont/a for use in the treatment of a disorder affecting an eyelid muscle of a subject

Publications (3)

Publication Number Publication Date
JP2024534541A JP2024534541A (ja) 2024-09-20
JP2024534541A5 true JP2024534541A5 (https=) 2025-09-04
JPWO2023047127A5 JPWO2023047127A5 (https=) 2025-09-04

Family

ID=83507580

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024518109A Pending JP2024534541A (ja) 2021-09-23 2022-09-23 被験体の眼瞼筋を冒す障害の治療における使用のための改変BoNT/A

Country Status (7)

Country Link
US (1) US20250179461A1 (https=)
EP (1) EP4404955A1 (https=)
JP (1) JP2024534541A (https=)
KR (1) KR20240067100A (https=)
AU (1) AU2022351260A1 (https=)
CA (1) CA3228712A1 (https=)
WO (1) WO2023047127A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202206361D0 (en) * 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of a facial dystonia
GB202214229D0 (en) 2022-09-28 2022-11-09 Ipsen Biopharm Ltd Clostridial neurotoxins comprising an activating endosomal protease cleavage site
GB202214232D0 (en) 2022-09-28 2022-11-09 Ispen Biopharm Ltd Clostridial neurotoxins comprising an activating exogenous protease cleavage site
WO2025093844A1 (en) * 2023-11-01 2025-05-08 Ipsen Biopharm Limited Use of chimeric botulinum toxin a for treating blepharospasm and hemifacial spasm
GB202318884D0 (en) 2023-12-11 2024-01-24 Ipsen Biopharm Ltd Formulation

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE102004043009A1 (de) 2004-09-06 2006-03-23 Toxogen Gmbh Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen
DE102005019302A1 (de) 2005-04-26 2006-11-16 Toxogen Gmbh Carrier zum Targeting von Nervenzellen
ES2369558T3 (es) 2005-09-19 2011-12-01 Allergan, Inc. Toxinas clostridiales y toxinas clostridiales activables.
CA2758274C (en) 2009-04-14 2018-04-10 Mcw Research Foundation, Inc. Engineered botulinum neurotoxin
US8853360B2 (en) 2010-06-23 2014-10-07 Wisconsin Alumni Research Foundation Engineered botulinum neurotoxin C1 with selective substrate specificity
EP3162894B1 (en) 2011-05-19 2024-01-10 Ipsen Bioinnovation Limited Methods for the manufacture of proteolytically processed polypeptides
SG10201606666XA (en) 2012-05-30 2016-09-29 Harvard College Engineered Botulinum Neurotoxin
WO2014079495A1 (en) 2012-11-21 2014-05-30 Syntaxin Limited Methods for the manufacture of proteolytically processed polypeptides
GB201312317D0 (en) 2013-07-09 2013-08-21 Syntaxin Ltd Cationic neurotoxins
GB201407525D0 (en) 2014-04-29 2014-06-11 Syntaxin Ltd Manufacture of recombinant clostridium botulinum neurotoxins
PT3274364T (pt) 2015-03-26 2021-11-05 Harvard College Neurotoxina botulínica manipulada
GB201517450D0 (en) 2015-10-02 2015-11-18 Ipsen Biopharm Ltd Method
GB201607901D0 (en) 2016-05-05 2016-06-22 Ipsen Biopharm Ltd Chimeric neurotoxins

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