JP2024534384A5 - - Google Patents

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Publication number
JP2024534384A5
JP2024534384A5 JP2024516560A JP2024516560A JP2024534384A5 JP 2024534384 A5 JP2024534384 A5 JP 2024534384A5 JP 2024516560 A JP2024516560 A JP 2024516560A JP 2024516560 A JP2024516560 A JP 2024516560A JP 2024534384 A5 JP2024534384 A5 JP 2024534384A5
Authority
JP
Japan
Application number
JP2024516560A
Other languages
Japanese (ja)
Other versions
JPWO2023041934A5 (https=
JP2024534384A (ja
Filing date
Publication date
Priority claimed from GBGB2206357.2A external-priority patent/GB202206357D0/en
Application filed filed Critical
Priority claimed from PCT/GB2022/052361 external-priority patent/WO2023041934A1/en
Publication of JP2024534384A publication Critical patent/JP2024534384A/ja
Publication of JPWO2023041934A5 publication Critical patent/JPWO2023041934A5/ja
Publication of JP2024534384A5 publication Critical patent/JP2024534384A5/ja
Pending legal-status Critical Current

Links

JP2024516560A 2021-09-16 2022-09-16 頸部ジストニアを治療する用途の修飾BoNT/A Pending JP2024534384A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB202113262 2021-09-16
GB2113262.6 2021-09-16
GB2206357.2 2022-04-29
GBGB2206357.2A GB202206357D0 (en) 2022-04-29 2022-04-29 Treatment of cervical dystonia
PCT/GB2022/052361 WO2023041934A1 (en) 2021-09-16 2022-09-16 Modified bont/a for use in the treatment of cervical dystonia

Publications (3)

Publication Number Publication Date
JP2024534384A JP2024534384A (ja) 2024-09-20
JPWO2023041934A5 JPWO2023041934A5 (https=) 2025-09-25
JP2024534384A5 true JP2024534384A5 (https=) 2025-09-25

Family

ID=83457513

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024516560A Pending JP2024534384A (ja) 2021-09-16 2022-09-16 頸部ジストニアを治療する用途の修飾BoNT/A

Country Status (10)

Country Link
US (1) US20250129354A1 (https=)
EP (1) EP4401759B1 (https=)
JP (1) JP2024534384A (https=)
KR (1) KR20240067070A (https=)
CN (1) CN121534167A (https=)
AU (1) AU2022348206A1 (https=)
CA (1) CA3231083A1 (https=)
FI (1) FI4401759T3 (https=)
MA (1) MA66538B1 (https=)
WO (1) WO2023041934A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202206353D0 (en) * 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of cervical dystonia
GB202214229D0 (en) 2022-09-28 2022-11-09 Ipsen Biopharm Ltd Clostridial neurotoxins comprising an activating endosomal protease cleavage site
GB202214232D0 (en) 2022-09-28 2022-11-09 Ispen Biopharm Ltd Clostridial neurotoxins comprising an activating exogenous protease cleavage site
WO2025093844A1 (en) * 2023-11-01 2025-05-08 Ipsen Biopharm Limited Use of chimeric botulinum toxin a for treating blepharospasm and hemifacial spasm
GB202318884D0 (en) 2023-12-11 2024-01-24 Ipsen Biopharm Ltd Formulation

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE102004043009A1 (de) 2004-09-06 2006-03-23 Toxogen Gmbh Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen
DE102005019302A1 (de) 2005-04-26 2006-11-16 Toxogen Gmbh Carrier zum Targeting von Nervenzellen
ES2369558T3 (es) 2005-09-19 2011-12-01 Allergan, Inc. Toxinas clostridiales y toxinas clostridiales activables.
CA2758274C (en) 2009-04-14 2018-04-10 Mcw Research Foundation, Inc. Engineered botulinum neurotoxin
US8853360B2 (en) 2010-06-23 2014-10-07 Wisconsin Alumni Research Foundation Engineered botulinum neurotoxin C1 with selective substrate specificity
EP3162894B1 (en) 2011-05-19 2024-01-10 Ipsen Bioinnovation Limited Methods for the manufacture of proteolytically processed polypeptides
SG10201606666XA (en) 2012-05-30 2016-09-29 Harvard College Engineered Botulinum Neurotoxin
WO2014079495A1 (en) 2012-11-21 2014-05-30 Syntaxin Limited Methods for the manufacture of proteolytically processed polypeptides
GB201312317D0 (en) 2013-07-09 2013-08-21 Syntaxin Ltd Cationic neurotoxins
GB201407525D0 (en) 2014-04-29 2014-06-11 Syntaxin Ltd Manufacture of recombinant clostridium botulinum neurotoxins
PT3274364T (pt) 2015-03-26 2021-11-05 Harvard College Neurotoxina botulínica manipulada
GB201517450D0 (en) 2015-10-02 2015-11-18 Ipsen Biopharm Ltd Method
GB201607901D0 (en) 2016-05-05 2016-06-22 Ipsen Biopharm Ltd Chimeric neurotoxins

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