JP2024530170A - 改善された抗微生物活性を有するバクテリオファージ - Google Patents

改善された抗微生物活性を有するバクテリオファージ Download PDF

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JP2024530170A
JP2024530170A JP2024506733A JP2024506733A JP2024530170A JP 2024530170 A JP2024530170 A JP 2024530170A JP 2024506733 A JP2024506733 A JP 2024506733A JP 2024506733 A JP2024506733 A JP 2024506733A JP 2024530170 A JP2024530170 A JP 2024530170A
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seq
identity
polynucleotide sequence
bacteriophage
bacteriophages
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JP2024530170A5 (enExample
Inventor
ルミール，セバスチャン
ソリアガ，アンフェラ・ビー
グエン，カトリーナ・トラム・アン
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アルマタ・ファーマシューティカルズ・インコーポレーテッド
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    • C—CHEMISTRY; METALLURGY
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/02—Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/02003—Poly(beta-D-mannuronate) lyase (4.2.2.3)
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    • C12Y402/02—Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/02011—Poly(alpha-L-guluronate) lyase (4.2.2.11), i.e. alginase II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2795/00—Bacteriophages
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
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    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
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    • C—CHEMISTRY; METALLURGY
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
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    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10111—Myoviridae
    • C12N2795/10132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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    • C12N2795/10211—Podoviridae
    • C12N2795/10232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
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  • Biomedical Technology (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2024506733A 2021-08-02 2022-08-02 改善された抗微生物活性を有するバクテリオファージ Pending JP2024530170A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163228504P 2021-08-02 2021-08-02
US63/228,504 2021-08-02
PCT/US2022/074446 WO2023015195A1 (en) 2021-08-02 2022-08-02 Bacteriophages with improved antimicrobial activity

Publications (2)

Publication Number Publication Date
JP2024530170A true JP2024530170A (ja) 2024-08-16
JP2024530170A5 JP2024530170A5 (enExample) 2025-08-13

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JP2024506733A Pending JP2024530170A (ja) 2021-08-02 2022-08-02 改善された抗微生物活性を有するバクテリオファージ

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US (1) US20240352428A1 (enExample)
EP (1) EP4380586A4 (enExample)
JP (1) JP2024530170A (enExample)
KR (1) KR20240042484A (enExample)
CN (1) CN118591383A (enExample)
AU (1) AU2022323171A1 (enExample)
CA (1) CA3227846A1 (enExample)
IL (1) IL310549A (enExample)
WO (1) WO2023015195A1 (enExample)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0300597D0 (en) * 2003-01-10 2003-02-12 Microbiological Res Authority Phage biofilms
WO2011044279A2 (en) * 2009-10-06 2011-04-14 Bio Architecture Lab, Inc. Microbial systems for producing commodity chemicals
CN113215115B (zh) * 2014-12-16 2024-07-02 C3J治疗公司 用于体外病毒基因组工程的组合物和方法
US11421222B2 (en) * 2019-06-18 2022-08-23 Eligo Bioscience Bacterial delivery vehicles comprising tracer nucleic acid sequences

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Publication number Publication date
US20240352428A1 (en) 2024-10-24
WO2023015195A1 (en) 2023-02-09
CN118591383A (zh) 2024-09-03
AU2022323171A1 (en) 2024-03-07
CA3227846A1 (en) 2023-02-09
IL310549A (en) 2024-03-01
KR20240042484A (ko) 2024-04-02
EP4380586A4 (en) 2025-09-03
EP4380586A1 (en) 2024-06-12

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