|
US4140755A
(en)
|
1976-02-13 |
1979-02-20 |
Hoffmann-La Roche Inc. |
Sustained release tablet formulations
|
|
US4191184A
(en)
|
1977-01-06 |
1980-03-04 |
Carlisle Jeffrey A |
Intravenous infusion regulation system with reciprocal metering means
|
|
US4658038A
(en)
|
1982-10-07 |
1987-04-14 |
Research Foundation For Mental Hygiene, Inc. |
N-acylated 5-hydroxytryptophan amide derivatives
|
|
IL87710A
(en)
|
1987-09-18 |
1992-06-21 |
Ciba Geigy Ag |
Covered floating retard form for controlled release in gastric juice
|
|
FR2654931B1
(fr)
*
|
1989-11-24 |
1993-08-27 |
Trouillas Paul |
Compositions pharmaceutiques possedant une activite sur l'ataxie et les troubles de l'equilibre, cerebelleux ou autres, de toutes origines, comprenant l'association de l-5-hydroxytryptophane et de carbidopa.
|
|
IT1282650B1
(it)
*
|
1996-02-19 |
1998-03-31 |
Jagotec Ag |
Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
|
|
CA2290624C
(en)
|
1997-06-06 |
2006-12-05 |
John W. Shell |
Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs
|
|
US6635280B2
(en)
|
1997-06-06 |
2003-10-21 |
Depomed, Inc. |
Extending the duration of drug release within the stomach during the fed mode
|
|
IN186245B
(https=)
|
1997-09-19 |
2001-07-14 |
Ranbaxy Lab Ltd |
|
|
EP1063973B1
(en)
|
1998-03-19 |
2016-11-16 |
Bristol-Myers Squibb Company |
Biphasic controlled release delivery system for high solubility pharmaceuticals and method
|
|
US6488962B1
(en)
|
2000-06-20 |
2002-12-03 |
Depomed, Inc. |
Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
|
|
US7674480B2
(en)
|
2000-06-23 |
2010-03-09 |
Teva Pharmaceutical Industries Ltd. |
Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition
|
|
US6723340B2
(en)
|
2001-10-25 |
2004-04-20 |
Depomed, Inc. |
Optimal polymer mixtures for gastric retentive tablets
|
|
CA2409552A1
(en)
|
2001-10-25 |
2003-04-25 |
Depomed, Inc. |
Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
|
|
TWI312285B
(en)
|
2001-10-25 |
2009-07-21 |
Depomed Inc |
Methods of treatment using a gastric retained gabapentin dosage
|
|
US20060013875A1
(en)
|
2002-05-29 |
2006-01-19 |
Impax Laboratories, Inc. |
Combination immediate release controlled release levodopa/carbidopa dosage forms
|
|
US7094427B2
(en)
|
2002-05-29 |
2006-08-22 |
Impax Laboratories, Inc. |
Combination immediate release controlled release levodopa/carbidopa dosage forms
|
|
BR0314804A
(pt)
*
|
2002-09-28 |
2005-08-02 |
Mcneil Ppc Inc |
Forma de dosagem de liberação modificada
|
|
EP1542662A1
(en)
|
2002-09-28 |
2005-06-22 |
McNEIL-PPC, INC. |
Immediate release dosage form comprising shell having openings therein
|
|
AU2003293423A1
(en)
|
2002-12-06 |
2004-06-30 |
Xenoport, Inc. |
Carbidopa prodrugs and uses thereof
|
|
ITMI20041689A1
(it)
|
2004-09-01 |
2004-12-02 |
Bojidar Mihaylov Stankov |
Nuove formulazioni di rilascio controllato contenenti 5-idrossitriptofano e triptofano
|
|
US20080268045A1
(en)
|
2006-11-09 |
2008-10-30 |
Proprius Pharmaceuticals, Inc. |
Sustained release methotrexate formulations and methods of use thereof
|
|
KR20080076382A
(ko)
|
2007-02-15 |
2008-08-20 |
(주)아모레퍼시픽 |
실로스타졸의 제어방출 제제 및 그 제조방법
|
|
EP1980743B1
(en)
|
2007-04-10 |
2015-09-09 |
Nissan Motor Co., Ltd. |
Fuel pump driving device
|
|
US8969400B2
(en)
|
2007-10-01 |
2015-03-03 |
Duke University |
Pharmaceutical compositions of 5-hydroxytryptophan and serotonin-enhancing compound
|
|
KR101601649B1
(ko)
|
2008-04-18 |
2016-03-09 |
인텍 파마 리미티드 |
카르비도파／레보도파 위체류 약물 전달
|
|
ZA200903854B
(en)
|
2008-06-19 |
2011-02-23 |
Univ Of The Witwatesrand Johannesburg |
A gastroretentive pharmaceutical dosage form
|
|
JP2012500221A
(ja)
|
2008-08-15 |
2012-01-05 |
ディポメド，インコーポレイティド |
Ｃｎｓ障害の処理及び予防のための胃保持性医薬組成物
|
|
WO2011146611A1
(en)
|
2010-05-18 |
2011-11-24 |
Abon Pharmaceuticals, Llc |
Modified gastroretentive drug delivery system for amine drugs
|
|
US20130078290A1
(en)
*
|
2010-06-01 |
2013-03-28 |
Rubicon Research Private Limited |
Gastroretentive Dosage Forms Of GABA Analogs
|
|
EP2629615B1
(en)
|
2010-10-22 |
2018-10-10 |
Duke University |
Slow-release formulations of 5-hydroxytryptophan as an adjunct to pro-serotonergic therapies
|
|
CN103554005A
(zh)
|
2013-11-22 |
2014-02-05 |
长沙理工大学 |
一种左旋5-羟基色氨酸的简便合成新方法
|
|
US20170266112A1
(en)
|
2014-06-11 |
2017-09-21 |
Massachusetts Institute Of Technology |
Residence structures and related methods
|
|
HK1258050A1
(zh)
|
2015-10-23 |
2019-11-01 |
Lyndra Therapeutics, Inc. |
用於治疗剂缓释的胃驻留系统及其使用方法
|
|
BR112020015068A2
(pt)
|
2018-01-29 |
2021-01-05 |
Duke University |
Composições e métodos de melhoramento de biodisponibilidade de 5-hidroxitriptofano
|
|
CN112469400A
(zh)
*
|
2018-06-19 |
2021-03-09 |
新加坡国立大学 |
对于各种适应症的生物利用度更佳的5-羟色氨酸(5-htp)制剂
|
|
EP3820468A4
(en)
*
|
2018-07-11 |
2022-03-23 |
Duke University |
Use of sustained-release 5-hydroxytryptophan in treating gastrointestinal disorders
|