JP2024527627A5 - - Google Patents

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Publication number
JP2024527627A5
JP2024527627A5 JP2024503606A JP2024503606A JP2024527627A5 JP 2024527627 A5 JP2024527627 A5 JP 2024527627A5 JP 2024503606 A JP2024503606 A JP 2024503606A JP 2024503606 A JP2024503606 A JP 2024503606A JP 2024527627 A5 JP2024527627 A5 JP 2024527627A5
Authority
JP
Japan
Application number
JP2024503606A
Other languages
Japanese (ja)
Other versions
JP2024527627A (ja
JPWO2023002045A5 (https=
Filing date
Publication date
Priority claimed from EP21187424.3A external-priority patent/EP4122499A1/en
Application filed filed Critical
Publication of JP2024527627A publication Critical patent/JP2024527627A/ja
Publication of JP2024527627A5 publication Critical patent/JP2024527627A5/ja
Publication of JPWO2023002045A5 publication Critical patent/JPWO2023002045A5/ja
Pending legal-status Critical Current

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JP2024503606A 2021-07-23 2022-07-22 線維芽細胞活性化タンパク質阻害剤及びその使用 Pending JP2024527627A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21187424.3A EP4122499A1 (en) 2021-07-23 2021-07-23 Fibroblast activation protein inhibitors and use thereof
EP21187424.3 2021-07-23
PCT/EP2022/070693 WO2023002045A1 (en) 2021-07-23 2022-07-22 Fibroblast activation protein inhibitors and use thereof

Publications (3)

Publication Number Publication Date
JP2024527627A JP2024527627A (ja) 2024-07-25
JP2024527627A5 true JP2024527627A5 (https=) 2026-01-30
JPWO2023002045A5 JPWO2023002045A5 (https=) 2026-01-30

Family

ID=77042830

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024503606A Pending JP2024527627A (ja) 2021-07-23 2022-07-22 線維芽細胞活性化タンパク質阻害剤及びその使用

Country Status (11)

Country Link
US (1) US20240335569A1 (https=)
EP (2) EP4122499A1 (https=)
JP (1) JP2024527627A (https=)
KR (1) KR20240040092A (https=)
CN (1) CN117769443A (https=)
AU (1) AU2022313521A1 (https=)
CA (1) CA3224514A1 (https=)
CL (1) CL2024000200A1 (https=)
IL (1) IL310306A (https=)
MX (1) MX2024000866A (https=)
WO (1) WO2023002045A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4475900A1 (en) 2022-02-09 2024-12-18 Novartis AG Pharmaceutical compositions comprising a 225-actinium-labelled complex and a bismuth sequestering agent
EP4342890A1 (en) * 2022-09-21 2024-03-27 Erasmus University Rotterdam Medical Center Platform and scaffold for fap targeting agents
WO2025106939A1 (en) * 2023-11-16 2025-05-22 Praxis Biotech LLC Conjugates targeting fibroblast activation protein and uses thereof
CN119604492A (zh) * 2023-12-08 2025-03-11 北京师范大学 一种放射性标记fapi配合物及其制备方法和应用
WO2025167951A1 (zh) * 2024-02-07 2025-08-14 苏州博锐创合医药有限公司 一种成纤维细胞活化蛋白抑制剂
WO2025240871A1 (en) * 2024-05-16 2025-11-20 Purdue Research Foundation Chemically stable keto-amide-based fibroblast activation protein-targeted nanoparticle-based magnetic resonance imaging agent, compositions, and methods of use
CN118978511A (zh) * 2024-08-02 2024-11-19 江苏华益科技有限公司 一种靶向fap化合物及其制备方法

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Publication number Priority date Publication date Assignee Title
US4885363A (en) 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
US5021556A (en) 1987-07-22 1991-06-04 Neorx Corporation Method of radiolabeling chelating compounds comprising sulfur atoms with metal radionuclides
US5075099A (en) 1988-05-31 1991-12-24 Neorx Corporation Metal radionuclide chelating compounds for improved chelation kinetics
US5364613A (en) 1989-04-07 1994-11-15 Sieving Paul F Polychelants containing macrocyclic chelant moieties
US5367080A (en) 1990-11-08 1994-11-22 Sterling Winthrop Inc. Complexing agents and targeting radioactive immunoreagents useful in therapeutic and diagnostic imaging compositions and methods
US5965107A (en) 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5886142A (en) 1997-05-20 1999-03-23 Thomas Jefferson University Radiolabeled thrombus imaging agents
CN103370063A (zh) 2010-12-13 2013-10-23 免疫医疗公司 用于改善蛋白质、肽和其他分子的f-18标记的方法和组合物
DE102014115088A1 (de) 2014-10-16 2016-04-21 Sovicell Gmbh Bestimmung von Bindungskonstanten mittels Gleichgewichtsverlagerung
EA202090776A1 (ru) * 2017-10-23 2020-07-27 Дзе Джонс Хопкинс Юниверсити Визуализирующие и радиотерапевтические агенты, нацеленные на фибробласт-активирующий белок-альфа (fapalpha)
SG11202007180QA (en) * 2018-02-06 2020-08-28 Univ Heidelberg Fap inhibitor
DE102018126558A1 (de) * 2018-10-24 2020-04-30 Helmholtz-Zentrum Dresden - Rossendorf E.V. Markierungsvorläufer mit Quadratsäure-Kopplung
CN113811529A (zh) * 2018-12-21 2021-12-17 普拉西斯生物技术有限责任公司 成纤维细胞激活蛋白抑制剂

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