JP2024520898A - 再発性及び／又は難治性多発性骨髄腫の治療をモニタリングするための方法及び組成物 - Google Patents

再発性及び／又は難治性多発性骨髄腫の治療をモニタリングするための方法及び組成物 Download PDF

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JP2024520898A
JP2024520898A JP2023569779A JP2023569779A JP2024520898A JP 2024520898 A JP2024520898 A JP 2024520898A JP 2023569779 A JP2023569779 A JP 2023569779A JP 2023569779 A JP2023569779 A JP 2023569779A JP 2024520898 A JP2024520898 A JP 2024520898A
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sbcma
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therapy
blood sample
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ピラリセッティ，コダンダラーム
ギルギス，スゼット
ゴールドバーグ，ジェンナ
リン，シュン，シン ワン
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ヤンセン バイオテツク，インコーポレーテツド
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
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    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2023569779A 2021-05-11 2022-05-11 再発性及び／又は難治性多発性骨髄腫の治療をモニタリングするための方法及び組成物 Pending JP2024520898A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163187344P 2021-05-11 2021-05-11
US63/187,344 2021-05-11
PCT/US2022/072247 WO2022241430A1 (en) 2021-05-11 2022-05-11 Methods and compositions for monitoring the treatment of relapsed and/or refractory multiple myeloma

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JP2024520898A true JP2024520898A (ja) 2024-05-27
JP2024520898A5 JP2024520898A5 (https=) 2025-05-19
JPWO2022241430A5 JPWO2022241430A5 (https=) 2025-05-19

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US (2) US20220373550A1 (https=)
EP (1) EP4337962A1 (https=)
JP (1) JP2024520898A (https=)
KR (1) KR20240005919A (https=)
CN (1) CN117295949A (https=)
AU (1) AU2022273326A1 (https=)
CA (1) CA3219969A1 (https=)
MX (1) MX2023013412A (https=)
TW (1) TW202309522A (https=)
WO (1) WO2022241430A1 (https=)

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TWI781108B (zh) 2016-07-20 2022-10-21 比利時商健生藥品公司 抗ｇｐｒｃ５ｄ抗體、結合ｇｐｒｃ５ｄ與ｃｄ３之雙特異性抗原結合分子及其用途
CN116249548A (zh) 2020-05-11 2023-06-09 詹森生物科技公司 用于治疗多发性骨髓瘤的方法
IL312503A (en) 2021-11-03 2024-07-01 Janssen Biotech Inc Methods of treating cancers and enhancing efficacy of bcmaxcd3 bispecific antibodies
WO2024168192A1 (en) * 2023-02-10 2024-08-15 Celgene Corporation Assessment of bcma in biological samples
CN121358492A (zh) * 2023-04-19 2026-01-16 詹森生物科技公司 用于治疗多发性骨髓瘤的方法

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ATE87659T1 (de) 1986-09-02 1993-04-15 Enzon Lab Inc Bindungsmolekuele mit einzelpolypeptidkette.
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ATE199392T1 (de) 1992-12-04 2001-03-15 Medical Res Council Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
AUPO591797A0 (en) 1997-03-27 1997-04-24 Commonwealth Scientific And Industrial Research Organisation High avidity polyvalent and polyspecific reagents
UA74798C2 (uk) 1999-10-06 2006-02-15 Байоджен Айдек Ма Інк. Спосіб лікування раку у ссавця за допомогою поліпептиду, що протидіє взаємодії april з його рецепторами
WO2001024812A1 (en) 1999-10-06 2001-04-12 N.V. Nutricia USE OF TRANSFORMING GROWTH FACTOR β AND GROWTH FACTORS IN THE TREATMENT AND PREVENTION OF DISEASES OF THE INTESTINAL MUCOSA
US20030012783A1 (en) 2001-02-20 2003-01-16 Wayne Kindsvogel Antibodies that bind both BCMA and TACI
JP2011507519A (ja) 2007-12-19 2011-03-10 セントコア・オーソ・バイオテツク・インコーポレーテツド ｐＩＸ又はｐＶＩＩへの融合を介したヒトデノボｐＩＸファージディスプレイライブラリの設計及び作製、ベクター、抗体、及び方法
EP2406284B9 (en) 2009-03-10 2017-03-01 Biogen MA Inc. Anti-bcma antibodies
CN105384825B (zh) 2015-08-11 2018-06-01 南京传奇生物科技有限公司 一种基于单域抗体的双特异性嵌合抗原受体及其应用
US10072088B2 (en) 2015-08-17 2018-09-11 Janssen Pharmaceutica, Nv Anti-BCMA antibodies and uses thereof
TWI781108B (zh) 2016-07-20 2022-10-21 比利時商健生藥品公司 抗ｇｐｒｃ５ｄ抗體、結合ｇｐｒｃ５ｄ與ｃｄ３之雙特異性抗原結合分子及其用途
EP4282877A3 (en) 2016-08-10 2024-02-21 Legend Biotech Ireland Limited Chimeric antigen receptors targeting bcma and methods of use thereof
CN112955748A (zh) * 2018-10-31 2021-06-11 葛兰素史密斯克莱知识产权发展有限公司 治疗癌症的方法
AU2020377930A1 (en) * 2019-11-05 2022-05-19 Bristol-Myers Squibb Company Uses of anti-BCMA chimeric antigen receptors

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TW202309522A (zh) 2023-03-01
CN117295949A (zh) 2023-12-26
AU2022273326A1 (en) 2024-01-04
CA3219969A1 (en) 2022-11-17
KR20240005919A (ko) 2024-01-12
WO2022241430A1 (en) 2022-11-17
US20220373550A1 (en) 2022-11-24
US20250362298A1 (en) 2025-11-27
MX2023013412A (es) 2024-02-27
EP4337962A1 (en) 2024-03-20

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