JP2023548149A5 - - Google Patents
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- Publication number
- JP2023548149A5 JP2023548149A5 JP2023526248A JP2023526248A JP2023548149A5 JP 2023548149 A5 JP2023548149 A5 JP 2023548149A5 JP 2023526248 A JP2023526248 A JP 2023526248A JP 2023526248 A JP2023526248 A JP 2023526248A JP 2023548149 A5 JP2023548149 A5 JP 2023548149A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063106990P | 2020-10-29 | 2020-10-29 | |
| US63/106,990 | 2020-10-29 | ||
| PCT/US2021/045520 WO2022093357A1 (en) | 2020-10-29 | 2021-08-11 | Novel photocleavable mass-tags for multiplexed mass spectrometric imaging of tissues using biomolecular probes |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023548149A JP2023548149A (ja) | 2023-11-15 |
| JP2023548149A5 true JP2023548149A5 (https=) | 2024-08-13 |
| JPWO2022093357A5 JPWO2022093357A5 (https=) | 2024-08-13 |
| JP7752686B2 JP7752686B2 (ja) | 2025-10-10 |
Family
ID=78049511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023526248A Active JP7752686B2 (ja) | 2020-10-29 | 2021-08-11 | 生体分子プローブを使用した組織のマルチプレックス質量分析イメージングのための新規な光切断可能な質量タグ |
Country Status (9)
| Country | Link |
|---|---|
| US (12) | US12181481B2 (https=) |
| EP (1) | EP4237839A4 (https=) |
| JP (1) | JP7752686B2 (https=) |
| KR (2) | KR20240125080A (https=) |
| CN (1) | CN116457664B (https=) |
| AU (2) | AU2021372349B2 (https=) |
| CA (1) | CA3195979A1 (https=) |
| GB (7) | GB2628478A (https=) |
| WO (1) | WO2022093357A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115386965B (zh) * | 2022-08-30 | 2025-08-29 | 上海交通大学 | 基于空间交错编码多组学芯片及其制备方法与应用 |
| EP4638788A1 (en) * | 2022-12-21 | 2025-10-29 | 10X Genomics, Inc. | Analysis of analytes and spatial gene expression |
| GB202219855D0 (en) * | 2022-12-30 | 2023-02-15 | Univ Oxford Innovation Ltd | Affinity capture reagents for mass spectrometry |
| WO2024196780A2 (en) * | 2023-03-17 | 2024-09-26 | Regents Of The University Of Minnesota | Combined targeted and untargeted proteomics |
| WO2025076554A1 (en) * | 2023-10-06 | 2025-04-10 | The Regents Of The University Of California | Targeted cell profiling via in situ hybridization with mass spectrometry detection |
| WO2025242912A1 (en) * | 2024-05-23 | 2025-11-27 | Institut National de la Santé et de la Recherche Médicale | Conjugates for mass spectrometry imaging |
| WO2025255136A1 (en) * | 2024-06-03 | 2025-12-11 | The Johns Hopkins University | Systems and methods for spatial proteomics |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA236097A (en) | 1923-12-04 | Henry Peters John | Concrete roadway | |
| US5643722A (en) | 1994-05-11 | 1997-07-01 | Trustees Of Boston University | Methods for the detection and isolation of proteins |
| US5986076A (en) | 1994-05-11 | 1999-11-16 | Trustees Of Boston University | Photocleavable agents and conjugates for the detection and isolation of biomolecules |
| DE69738206T2 (de) * | 1996-11-06 | 2008-07-17 | Sequenom, Inc., San Diego | DNA-Diagnostik mittels Massenspektrometrie |
| US6218530B1 (en) * | 1998-06-02 | 2001-04-17 | Ambergen Inc. | Compounds and methods for detecting biomolecules |
| AU2002211402A1 (en) * | 2000-09-30 | 2002-04-15 | Diversa Corporation | Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating |
| JP2004510433A (ja) * | 2000-10-06 | 2004-04-08 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク | Ｄｎａおよびｒｎａを解読するための大量並行方法 |
| US7569392B2 (en) * | 2004-01-08 | 2009-08-04 | Vanderbilt University | Multiplex spatial profiling of gene expression |
| US20090166224A1 (en) * | 2004-05-05 | 2009-07-02 | Ziping Yang | Multi-lectin affinity chromatography and uses thereof |
| JP2008542784A (ja) | 2005-06-07 | 2008-11-27 | サントル、ナショナール、ド、ラ、ルシェルシュ、シアンティフィク、（セーエヌエルエス） | 組織切片のｍａｌｄｉ質量分析法による分析のためのイオンマトリックスの使用 |
| EP1957983A4 (en) * | 2005-11-21 | 2010-03-24 | Univ Columbia | DIGITAL MULTIPLEX IMMUNE PRESENCE USING A LIBRARY OF PHOTOSPARABLE MASS DAYS |
| WO2007087339A2 (en) * | 2006-01-24 | 2007-08-02 | Perkinelmer Las, Inc. | Multiplexed analyte quantitation by two-dimensional planar electrochromatography |
| US7964356B2 (en) * | 2007-01-16 | 2011-06-21 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| DK2725107T3 (da) * | 2007-10-19 | 2019-01-02 | Univ Columbia | DNA-sekventering med ikke-fluorescerende nukleotidreversible terminatorer og ddNTP'er modificeret med spaltbart mærke og nukleinsyre omfattende inosin med reversible terminatorer |
| US8906700B2 (en) | 2007-11-06 | 2014-12-09 | Ambergen, Inc. | Methods and compositions for phototransfer |
| GB0811574D0 (en) * | 2008-06-24 | 2008-07-30 | Trillion Genomics Ltd | Characterising planar samples by mass spectrometry |
| US9523680B2 (en) * | 2010-06-30 | 2016-12-20 | Ambergen, Inc. | Global Proteomic screening of random bead arrays using mass spectrometry imaging |
| EP2588144B1 (en) * | 2010-07-02 | 2018-05-09 | Ventana Medical Systems, Inc. | Detecting targets using mass tags and mass spectrometry |
| US9157921B2 (en) | 2011-05-18 | 2015-10-13 | Purdue Research Foundation | Method for diagnosing abnormality in tissue samples by combination of mass spectral and optical imaging |
| EP2912433B1 (en) * | 2012-10-26 | 2019-03-20 | Fluidigm Canada Inc. | Cell analysis by mass cytometry |
| EP2767832A1 (en) * | 2013-02-18 | 2014-08-20 | Imabiotech | Photo or chemolabile conjugates for molecules detection |
| US10041949B2 (en) | 2013-09-13 | 2018-08-07 | The Board Of Trustees Of The Leland Stanford Junior University | Multiplexed imaging of tissues using mass tags and secondary ion mass spectrometry |
| EP3119908A4 (en) | 2014-03-11 | 2018-02-21 | The Council Of The Queensland Institute Of Medical Research | Determining cancer aggressiveness, prognosis and responsiveness to treatment |
| CN107209934B (zh) * | 2014-12-03 | 2021-03-30 | 文塔纳医疗系统公司 | 用于定量分析异质生物标志物分布的方法、系统和装置 |
| JP6892087B2 (ja) * | 2015-06-12 | 2021-06-18 | ソニー・オリンパスメディカルソリューションズ株式会社 | 医療用画像取得システムおよび医療用撮像装置 |
| JP7109784B2 (ja) | 2015-10-23 | 2022-08-01 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 遺伝子編集のための進化したＣａｓ９蛋白質 |
| EP4339288A3 (en) * | 2016-03-18 | 2024-06-05 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| WO2019103996A1 (en) | 2017-11-21 | 2019-05-31 | Expansion Technologies | Expansion microscopy compatible and multiplexed in situ hybridization of formalin fixed paraffin embedded tissue sections for spatially resolved transcriptomics |
| US11078534B2 (en) * | 2017-11-27 | 2021-08-03 | Roche Molecular Systems, Inc. | Photocleavable nucleotide reagents with high stability |
| US11264221B2 (en) * | 2018-06-18 | 2022-03-01 | Fluidigm Canada Inc. | High resolution imaging apparatus and method |
| CN114174531A (zh) * | 2019-02-28 | 2022-03-11 | 10X基因组学有限公司 | 用空间条码化寡核苷酸阵列对生物分析物进行概况分析 |
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2021
- 2021-08-11 GB GB2404071.9A patent/GB2628478A/en not_active Withdrawn
- 2021-08-11 GB GB2111542.3A patent/GB2600519B/en active Active
- 2021-08-11 GB GB2216718.3A patent/GB2626908B/en active Active
- 2021-08-11 CA CA3195979A patent/CA3195979A1/en active Pending
- 2021-08-11 AU AU2021372349A patent/AU2021372349B2/en active Active
- 2021-08-11 GB GB2111548.0A patent/GB2604411B/en active Active
- 2021-08-11 JP JP2023526248A patent/JP7752686B2/ja active Active
- 2021-08-11 GB GB2501307.9A patent/GB2634847B/en active Active
- 2021-08-11 EP EP21887104.4A patent/EP4237839A4/en active Pending
- 2021-08-11 US US17/399,417 patent/US12181481B2/en active Active
- 2021-08-11 US US17/399,461 patent/US11789027B2/en active Active
- 2021-08-11 GB GB2111546.4A patent/GB2604670B/en active Active
- 2021-08-11 KR KR1020247026785A patent/KR20240125080A/ko active Pending
- 2021-08-11 GB GB2111540.7A patent/GB2605470B/en active Active
- 2021-08-11 US US17/399,390 patent/US11906527B2/en active Active
- 2021-08-11 KR KR1020237014451A patent/KR20230127204A/ko active Pending
- 2021-08-11 US US17/399,434 patent/US20220137066A1/en active Pending
- 2021-08-11 WO PCT/US2021/045520 patent/WO2022093357A1/en not_active Ceased
- 2021-08-11 CN CN202180073586.2A patent/CN116457664B/zh active Active
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2022
- 2022-07-12 US US17/862,990 patent/US11940447B2/en active Active
- 2022-07-13 US US17/863,928 patent/US12078639B2/en active Active
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2023
- 2023-06-21 US US18/212,456 patent/US12181482B2/en active Active
- 2023-10-26 US US18/495,089 patent/US20240077494A1/en active Pending
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2024
- 2024-02-28 US US18/590,471 patent/US12235277B2/en active Active
- 2024-05-30 US US18/678,276 patent/US20240319205A1/en active Pending
- 2024-07-09 AU AU2024204721A patent/AU2024204721B2/en active Active
- 2024-11-13 US US18/946,328 patent/US20250067751A1/en active Pending
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2025
- 2025-10-27 US US19/369,929 patent/US20260049992A1/en active Pending