JP2023544385A5 - - Google Patents

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Publication number
JP2023544385A5
JP2023544385A5 JP2023520289A JP2023520289A JP2023544385A5 JP 2023544385 A5 JP2023544385 A5 JP 2023544385A5 JP 2023520289 A JP2023520289 A JP 2023520289A JP 2023520289 A JP2023520289 A JP 2023520289A JP 2023544385 A5 JP2023544385 A5 JP 2023544385A5
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JP
Japan
Application number
JP2023520289A
Other languages
Japanese (ja)
Other versions
JP2023544385A (ja
JPWO2022072447A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/052580 external-priority patent/WO2022072447A1/en
Publication of JP2023544385A publication Critical patent/JP2023544385A/ja
Publication of JP2023544385A5 publication Critical patent/JP2023544385A5/ja
Publication of JPWO2022072447A5 publication Critical patent/JPWO2022072447A5/ja
Pending legal-status Critical Current

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JP2023520289A 2020-10-01 2021-09-29 Snca関連神経変性疾患を治療又は予防するためのsnca irna組成物及びその使用方法 Pending JP2023544385A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063086495P 2020-10-01 2020-10-01
US63/086,495 2020-10-01
PCT/US2021/052580 WO2022072447A1 (en) 2020-10-01 2021-09-29 Snca irna compositions and methods of use thereof for treating or preventing snca-associated neurodegenerative diseases

Publications (3)

Publication Number Publication Date
JP2023544385A JP2023544385A (ja) 2023-10-23
JP2023544385A5 true JP2023544385A5 (https=) 2024-10-07
JPWO2022072447A5 JPWO2022072447A5 (https=) 2024-10-07

Family

ID=80950831

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023520289A Pending JP2023544385A (ja) 2020-10-01 2021-09-29 Snca関連神経変性疾患を治療又は予防するためのsnca irna組成物及びその使用方法

Country Status (12)

Country Link
US (1) US20240011032A1 (https=)
EP (1) EP4221838A4 (https=)
JP (1) JP2023544385A (https=)
KR (1) KR20230079405A (https=)
CN (1) CN116710107A (https=)
AR (1) AR123679A1 (https=)
AU (1) AU2021353935A1 (https=)
CA (1) CA3193830A1 (https=)
IL (1) IL301712A (https=)
MX (1) MX2023003810A (https=)
TW (1) TW202229551A (https=)
WO (1) WO2022072447A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119630791A (zh) * 2022-05-13 2025-03-14 迪克纳制药公司 用于抑制snca表达的组合物和方法
US20260103703A1 (en) * 2022-09-29 2026-04-16 Atalanta Therapeutics, Inc. siRNA COMPOSITIONS AND METHODS TARGETING ALPHA-SYNUCLEIN NUCLEIC ACIDS
WO2024166019A1 (en) * 2023-02-08 2024-08-15 Biorchestra Co., Ltd. Sirna targeting alpha-synuclein and uses thereof
AU2024335806A1 (en) * 2023-09-07 2026-04-23 Janssen Pharmaceutica Nv SNCA siRNA AND USES THEREOF
WO2025162214A1 (en) * 2024-01-30 2025-08-07 Shanghai Argo Biopharmaceutical Co., Ltd. Compositions and methods for inhibiting expression of synuclein alpha (snca) gene
TW202547527A (zh) * 2024-02-08 2025-12-16 日商泰爾茂股份有限公司 寡核苷酸

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006006948A2 (en) * 2002-11-14 2006-01-19 Dharmacon, Inc. METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY
EP2508608A1 (en) * 2003-06-09 2012-10-10 Alnylam Pharmaceuticals Inc. Method of treating neurodegenerative disease
WO2005045034A2 (en) * 2003-10-23 2005-05-19 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED TREATMENT OF PARKINSON DISEASE USING SHORT INTERERING NUCLEIC ACID (siNA)
US20080003570A1 (en) * 2004-12-22 2008-01-03 The General Hospital Corporation Translation enhancer elements of genes encoding human Tau protein and human alpha-synuclein protein
US20100105134A1 (en) * 2007-03-02 2010-04-29 Mdrna, Inc. Nucleic acid compounds for inhibiting gene expression and uses thereof
WO2009079399A2 (en) * 2007-12-14 2009-06-25 Alnylam Pharmaceuticals, Inc. Method of treating neurodegenerative disease
WO2012027713A2 (en) * 2010-08-26 2012-03-01 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibition of snca
CA3077910A1 (en) * 2010-11-17 2012-05-24 Ionis Pharmaceuticals, Inc. Modulation of alpha synuclein expression
CN108728533B (zh) * 2017-04-20 2022-06-14 常青 用于髓母细胞瘤分子分型的基因群以及snca基因作为4型髓母细胞瘤的生物标志物的用途
AU2019207859A1 (en) * 2018-01-12 2020-07-02 Roche Innovation Center Copenhagen A/S Alpha-synuclein antisense oligonucleotides and uses thereof
WO2019217459A1 (en) * 2018-05-07 2019-11-14 Alnylam Pharmaceuticals, Inc. Extrahepatic delivery
EP3830265A1 (en) * 2018-08-03 2021-06-09 Genzyme Corporation Variant rnai against alpha-synuclein

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