JP2023540756A5 - - Google Patents

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Publication number
JP2023540756A5
JP2023540756A5 JP2023514976A JP2023514976A JP2023540756A5 JP 2023540756 A5 JP2023540756 A5 JP 2023540756A5 JP 2023514976 A JP2023514976 A JP 2023514976A JP 2023514976 A JP2023514976 A JP 2023514976A JP 2023540756 A5 JP2023540756 A5 JP 2023540756A5
Authority
JP
Japan
Application number
JP2023514976A
Other languages
Japanese (ja)
Other versions
JP2023540756A (ja
JPWO2022051633A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/049081 external-priority patent/WO2022051633A2/en
Publication of JP2023540756A publication Critical patent/JP2023540756A/ja
Publication of JPWO2022051633A5 publication Critical patent/JPWO2022051633A5/ja
Publication of JP2023540756A5 publication Critical patent/JP2023540756A5/ja
Pending legal-status Critical Current

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JP2023514976A 2020-09-04 2021-09-03 向上した形質導入効率及び脳内における広範な分布を有する組換えアデノ随伴ウイルスベクターの新規の操作されたキャプシド血清型 Pending JP2023540756A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063074548P 2020-09-04 2020-09-04
US63/074,548 2020-09-04
PCT/US2021/049081 WO2022051633A2 (en) 2020-09-04 2021-09-03 Novel engineered capsid serotype of recombinant adeno-associated viral vector with enhanced transduction efficiency and widespread distribution in the brain

Publications (3)

Publication Number Publication Date
JP2023540756A JP2023540756A (ja) 2023-09-26
JPWO2022051633A5 JPWO2022051633A5 (https=) 2024-09-11
JP2023540756A5 true JP2023540756A5 (https=) 2024-09-11

Family

ID=80491526

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023514976A Pending JP2023540756A (ja) 2020-09-04 2021-09-03 向上した形質導入効率及び脳内における広範な分布を有する組換えアデノ随伴ウイルスベクターの新規の操作されたキャプシド血清型

Country Status (7)

Country Link
US (1) US20230330267A1 (https=)
EP (1) EP4208557A4 (https=)
JP (1) JP2023540756A (https=)
CN (1) CN116249541A (https=)
AU (1) AU2021335601A1 (https=)
CA (1) CA3191543A1 (https=)
WO (1) WO2022051633A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240158861A1 (en) * 2021-04-23 2024-05-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for treating cell senescence accumulation related disease
WO2025059678A1 (en) * 2023-09-15 2025-03-20 Ohio State Innovation Foundation Novel engineered capsid serotypes of recombinant adeno-associated viral vectors with reduced liver tropism

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1486567A1 (en) * 2003-06-11 2004-12-15 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Improved adeno-associated virus (AAV) vector for gene therapy
WO2009120978A2 (en) * 2008-03-27 2009-10-01 The Ohio State University Treatment of metabolic-related disorders using hypothalamic gene transfer of bdnf and compositions therfor
IL248102B (en) * 2014-05-02 2022-07-01 Genzyme Corp aav vectors for gene therapy of the central nervous system and retina
MX2020002148A (es) * 2017-08-25 2020-07-20 Ovid Therapeutics Inc Vectores adenoasociados recombinantes.
EP3793615A2 (en) * 2018-05-16 2021-03-24 Voyager Therapeutics, Inc. Directed evolution of aav to improve tropism for cns

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