JP2023535726A - 増強ウイルス様粒子および細胞への送達のためのその使用方法 - Google Patents

増強ウイルス様粒子および細胞への送達のためのその使用方法 Download PDF

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JP2023535726A
JP2023535726A JP2023504545A JP2023504545A JP2023535726A JP 2023535726 A JP2023535726 A JP 2023535726A JP 2023504545 A JP2023504545 A JP 2023504545A JP 2023504545 A JP2023504545 A JP 2023504545A JP 2023535726 A JP2023535726 A JP 2023535726A
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cargo
protein
evlp
editing
crispr
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JP2023535726A5 (https=
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ジョング，ジェイ．，キース
カベセイラス，ピーター
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Harvard University
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    • C12N2740/10011—Retroviridae
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    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20223—Virus like particles [VLP]
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    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20251—Methods of production or purification of viral material
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    • C12N2800/00—Nucleic acids vectors
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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JP2023504545A 2020-07-24 2021-07-26 増強ウイルス様粒子および細胞への送達のためのその使用方法 Pending JP2023535726A (ja)

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Application Number Priority Date Filing Date Title
US202063056125P 2020-07-24 2020-07-24
US63/056,125 2020-07-24
PCT/US2021/043151 WO2022020800A2 (en) 2020-07-24 2021-07-26 Enhanced virus-like particles and methods of use thereof for delivery to cells

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JP2023535726A true JP2023535726A (ja) 2023-08-21
JP2023535726A5 JP2023535726A5 (https=) 2024-08-07
JPWO2022020800A5 JPWO2022020800A5 (https=) 2024-08-07

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US (2) US12319938B2 (https=)
EP (1) EP4185600A4 (https=)
JP (1) JP2023535726A (https=)
KR (1) KR20230043151A (https=)
CN (1) CN116670154A (https=)
AU (1) AU2021310950A1 (https=)
BR (1) BR112023001272A2 (https=)
CA (1) CA3189601A1 (https=)
GB (1) GB2613486A (https=)
IL (1) IL300001A (https=)
MX (1) MX2023001028A (https=)
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KR20210055733A (ko) 2018-09-07 2021-05-17 빔 테라퓨틱스, 인크. 핵염기 편집 시스템을 전달하기 위한 조성물 및 방법
WO2020252455A1 (en) 2019-06-13 2020-12-17 The General Hospital Corporation Engineered human-endogenous virus-like particles and methods of use thereof for delivery to cells
EP4185600A4 (en) 2020-07-24 2024-12-04 The General Hospital Corporation Enhanced virus-like particles and methods of use thereof for delivery to cells
CN120303407A (zh) * 2022-05-17 2025-07-11 恩维洛普治疗有限责任公司 用于有效体内递送的组合物和方法
US20240189247A1 (en) * 2022-11-16 2024-06-13 The General Hospital Corporation Minimal Human-Derived Virus-Like Particles and Methods of Use Thereof for Delivery of Biomolecules
EP4638470A1 (en) * 2022-12-21 2025-10-29 BASF Agricultural Solutions US LLC Increased editing efficiency by co-delivery of rnp with nucleic acid
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CN119161426A (zh) * 2023-06-09 2024-12-20 深圳市先康达生命科学有限公司 用于转导nk细胞假型化慢病毒载体的包膜糖蛋白及其应用
WO2025051799A1 (en) 2023-09-05 2025-03-13 Aarhus Universitet Dna-encoded fusion proteins for incorporation of prime editing protein/rna complexes in virus-like particles
CN121794285A (zh) * 2023-09-09 2026-04-03 正基基因科技有限公司 工程化蛋白质递送载体
KR20250097002A (ko) * 2023-12-20 2025-06-30 성균관대학교산학협력단 Oct4, Sox2, Klf4 단백질을 포함하는 엔지니어링된 바이러스-유사 입자를 유효성분으로 포함하는 노화의 예방 또는 치료용 약제학적 조성물

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