JP2023527315A - Ｐｄ－ｌ１を標的とするための方法及び組成物 - Google Patents

Ｐｄ－ｌ１を標的とするための方法及び組成物 Download PDF

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JP2023527315A
JP2023527315A JP2022571280A JP2022571280A JP2023527315A JP 2023527315 A JP2023527315 A JP 2023527315A JP 2022571280 A JP2022571280 A JP 2022571280A JP 2022571280 A JP2022571280 A JP 2022571280A JP 2023527315 A JP2023527315 A JP 2023527315A
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alkyl
nitrogen
heterocyclyl
membered
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JP2023527315A5 (https=
JPWO2021236771A5 (https=
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ウー，トンフェイ
ジャン－マリ ベルナール ラボワソン，ピエール
ディミトローヴァ ストイチェヴァ，アンティトサ
ゴンザルヴェス，フランソワ
デヴァル，ジェローム
リュウ，チェン
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アリゴス セラピューティクス インコーポレイテッド
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    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
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    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
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    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
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    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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JP2022571280A 2020-05-22 2021-05-19 Ｐｄ－ｌ１を標的とするための方法及び組成物 Ceased JP2023527315A (ja)

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US202063028882P 2020-05-22 2020-05-22
US63/028,882 2020-05-22
US202163159075P 2021-03-10 2021-03-10
US63/159,075 2021-03-10
PCT/US2021/033159 WO2021236771A1 (en) 2020-05-22 2021-05-19 Methods and compositions for targeting pd-l1

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JP2023527315A5 JP2023527315A5 (https=) 2024-05-27
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