JP2022524037A5 - - Google Patents
Info
- Publication number
- JP2022524037A5 JP2022524037A5 JP2021552850A JP2021552850A JP2022524037A5 JP 2022524037 A5 JP2022524037 A5 JP 2022524037A5 JP 2021552850 A JP2021552850 A JP 2021552850A JP 2021552850 A JP2021552850 A JP 2021552850A JP 2022524037 A5 JP2022524037 A5 JP 2022524037A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962815187P | 2019-03-07 | 2019-03-07 | |
| US62/815,187 | 2019-03-07 | ||
| US201962822544P | 2019-03-22 | 2019-03-22 | |
| US62/822,544 | 2019-03-22 | ||
| US201962845218P | 2019-05-08 | 2019-05-08 | |
| US62/845,218 | 2019-05-08 | ||
| US201962855814P | 2019-05-31 | 2019-05-31 | |
| US62/855,814 | 2019-05-31 | ||
| US201962866270P | 2019-06-25 | 2019-06-25 | |
| US62/866,270 | 2019-06-25 | ||
| US201962873455P | 2019-07-12 | 2019-07-12 | |
| US62/873,455 | 2019-07-12 | ||
| US201962875772P | 2019-07-18 | 2019-07-18 | |
| US62/875,772 | 2019-07-18 | ||
| US201962884600P | 2019-08-08 | 2019-08-08 | |
| US62/884,600 | 2019-08-08 | ||
| US201962902171P | 2019-09-18 | 2019-09-18 | |
| US62/902,171 | 2019-09-18 | ||
| PCT/US2020/021568 WO2020181264A1 (en) | 2019-03-07 | 2020-03-06 | Rna-guided dna integration using tn7-like transposons |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022524037A JP2022524037A (ja) | 2022-04-27 |
| JP2022524037A5 true JP2022524037A5 (https=) | 2023-03-13 |
| JPWO2020181264A5 JPWO2020181264A5 (https=) | 2023-03-13 |
| JP7733576B2 JP7733576B2 (ja) | 2025-09-03 |
Family
ID=72334850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021552850A Active JP7733576B2 (ja) | 2019-03-07 | 2020-03-06 | Ｔｎ７様トランスポゾンを用いたＲＮＡ誘導ＤＮＡ組込み |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10947534B2 (https=) |
| EP (1) | EP3935179A4 (https=) |
| JP (1) | JP7733576B2 (https=) |
| KR (1) | KR20210149060A (https=) |
| CN (1) | CN113795587A (https=) |
| AU (1) | AU2020232850B2 (https=) |
| BR (1) | BR112021017655A2 (https=) |
| CA (1) | CA3132197A1 (https=) |
| IL (1) | IL286089A (https=) |
| SG (1) | SG11202109550TA (https=) |
| WO (1) | WO2020181264A1 (https=) |
| ZA (1) | ZA202106516B (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019090175A1 (en) | 2017-11-02 | 2019-05-09 | Arbor Biotechnologies, Inc. | Novel crispr-associated transposon systems and components |
| US20220372521A1 (en) * | 2019-08-14 | 2022-11-24 | The Trustees Of Columbia University In The City Of New York | Rna-guided dna integration and modification |
| AU2020373064A1 (en) * | 2019-11-01 | 2022-05-26 | Massachusetts Institute Of Technology | Type I-B CRISPR-associated transposase systems |
| CA3171941A1 (en) * | 2020-03-16 | 2021-09-23 | Joseph E. Peters | Compositions and methods comprising improved guide rnas |
| WO2021195532A1 (en) * | 2020-03-27 | 2021-09-30 | The Trustees Of Columbia University In The City Of New York | Genome engineering using crispr rna-guided integrases |
| US20240287486A1 (en) * | 2020-04-24 | 2024-08-29 | University Of Massachusetts | Improved cas 12a/nls mediated therapeutic gene editing platforms |
| US20250032629A1 (en) * | 2020-05-19 | 2025-01-30 | Anygen Co., Ltd. | Novel nucleolin-binding peptide and use thereof |
| CN116323971A (zh) * | 2020-08-18 | 2023-06-23 | Illumina公司 | 核酸的序列特异性靶向转座和选择以及分选 |
| EP4217499A4 (en) * | 2020-09-24 | 2025-02-12 | Metagenomi, Inc. | Systems and methods for transposing cargo nucleotide sequences |
| CA3194645A1 (en) * | 2020-10-08 | 2022-04-14 | The Broad Institute, Inc. | Type i crispr-associated transposase systems |
| WO2022147321A1 (en) * | 2020-12-30 | 2022-07-07 | The Broad Institute, Inc. | Type i-b crispr-associated transposase systems |
| WO2022150651A1 (en) * | 2021-01-07 | 2022-07-14 | The Broad Institute, Inc. | Dna nuclease guided transposase compositions and methods of use thereof |
| WO2022162623A1 (en) * | 2021-01-28 | 2022-08-04 | Arbor Biotechnologies, Inc. | Crispr-associated transposon systems and methods of using same |
| US20240301445A1 (en) * | 2021-01-28 | 2024-09-12 | Arbor Biotechnologies, Inc. | Crispr-associated transposon systems and methods of using same |
| CN112852921B (zh) * | 2021-03-16 | 2023-06-20 | 中国科学院长春应用化学研究所 | 一种基于即时检测试纸条的核酸检测方法、检测探针及其试剂盒 |
| CN115369098A (zh) * | 2021-05-17 | 2022-11-22 | 中国科学院分子植物科学卓越创新中心 | 一种新型crispr相关转座酶 |
| IL309148A (en) * | 2021-06-07 | 2024-02-01 | Univ Columbia | Crispr-transposon systems for dna modification |
| CA3223080A1 (en) * | 2021-06-17 | 2022-12-22 | Samuel Henry Sternberg | Systems, methods, and components for rna-guided effector recruitment |
| US20230159914A1 (en) * | 2021-06-24 | 2023-05-25 | Digenomix Corporation | Methods for reconstructing single cell genome |
| WO2023004422A2 (en) * | 2021-07-22 | 2023-01-26 | Arbor Biotechnologies, Inc. | Crispr-associated transposon systems and methods of using same |
| US20250066819A1 (en) * | 2021-08-16 | 2025-02-27 | Board Of Regents, The University Of Texas System | Crispr-associated transposons and uses thereof |
| EP4399312A4 (en) * | 2021-09-08 | 2025-09-03 | Metagenomi Inc | SYSTEMS AND METHODS FOR TRANSPOSITION OF CHARGED NUCLEOTIDE SEQUENCES |
| TWI821883B (zh) * | 2022-01-26 | 2023-11-11 | 國立清華大學 | 大腸桿菌基因編輯系統及其基因編輯方法 |
| US20250197458A1 (en) * | 2022-02-09 | 2025-06-19 | Cornell University | Adaptations for high efficiency i-f3-crispr-cas systems for guide rna-directed transposition in human cells |
| CA3244789A1 (en) * | 2022-02-23 | 2023-08-31 | Metagenomi Therapeutics, Inc. | FUSE PROTEINS |
| MX2024010333A (es) * | 2022-02-23 | 2024-08-30 | Metagenomi Inc | Sistemas y metodos para transponer secuencias de nucleotidos de carga. |
| CN114457100B (zh) * | 2022-03-03 | 2023-06-09 | 江南大学 | 一种基于CRISPR/Cpf1的大肠杆菌基因编辑系统及其应用 |
| US20250237648A1 (en) * | 2022-04-13 | 2025-07-24 | Baylor College Of Medicine | Bacterial biosensors for diagnosing and treating inflammation |
| WO2023204594A1 (ko) * | 2022-04-19 | 2023-10-26 | 서울대학교산학협력단 | 태그멘테이션을 이용한 벡터 삽입위치 검출 및 클론 정량 방법 |
| WO2023205267A1 (en) * | 2022-04-20 | 2023-10-26 | The Administrators Of The Tulane Educational Fund | Enhanced cell-free bacteriophage synthesis by genetic modulation of bacterial transcription/translation machinery (txtl) machinery |
| US20250290093A1 (en) * | 2022-04-29 | 2025-09-18 | Cz Biohub Sf, Llc | High capacity lentiviral vectors |
| EP4536817A1 (en) | 2022-06-07 | 2025-04-16 | Institut National de la Recherche pour l'Agriculture, l'Alimentation et l'Environnement | Attp mv4-derived site-specific recombination and its use for integration of sequence of interest |
| EP4536834A2 (en) * | 2022-06-08 | 2025-04-16 | North Carolina State University | Recombinant type i-f3 transposon-associated crispr-cas systems and methods of use |
| EP4569120A2 (en) * | 2022-06-13 | 2025-06-18 | The Trustees Of Columbia University In The City Of New York | Crispr-transposon systems for dna modification |
| CN118599809A (zh) * | 2022-07-07 | 2024-09-06 | 山东舜丰生物科技有限公司 | Cas酶及其应用 |
| KR102793465B1 (ko) * | 2022-10-19 | 2025-04-10 | 성균관대학교산학협력단 | Tn7-유사 타입 CrisprCAS를 이용한 코리네박테리움 글루타미쿰(Corynebacterium glutamicum)균 유전체 내 유전자 삽입 시스템 |
| JP2026500148A (ja) * | 2022-12-01 | 2026-01-06 | アーク リサーチ インスティテュート | 核酸操作のためのプログラム可能なｄｎａトランスポザーゼ |
| WO2024124048A1 (en) * | 2022-12-07 | 2024-06-13 | The Trustees Of Columbia University In The City Of New York | Systems and methods for rna-guided dna integration |
| CN116162640A (zh) * | 2023-01-30 | 2023-05-26 | 态创生物科技(广州)有限公司 | 大肠杆菌Rosetta菌株及其在催化合成α-熊果苷中的应用 |
| EP4665406A1 (en) * | 2023-02-14 | 2025-12-24 | The Trustees of Columbia University in the City of New York | Crispr-transposon systems and components |
| CN119842702B (zh) * | 2023-10-17 | 2025-11-28 | 清华大学 | 一种工程改造的dear核酸操纵系统的制备方法 |
| US20250257365A1 (en) * | 2024-02-09 | 2025-08-14 | California Institute Of Technology | Targeted DNA Integration in Plants by CRISPR-Associated Transposases (CASTs) |
| CN118460583B (zh) * | 2024-07-15 | 2024-10-29 | 苏州左旋星生物科技有限公司 | 用于靶向大肠杆菌多基因位点编辑的载体及其应用 |
| CN119752847B (zh) * | 2024-12-26 | 2025-12-05 | 崖州湾国家实验室 | 一种高温耐受型的TnpB核酸酶在核酸检测及基因编辑中的应用 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5451513A (en) | 1990-05-01 | 1995-09-19 | The State University of New Jersey Rutgers | Method for stably transforming plastids of multicellular plants |
| US5576198A (en) | 1993-12-14 | 1996-11-19 | Calgene, Inc. | Controlled expression of transgenic constructs in plant plastids |
| US5545817A (en) | 1994-03-11 | 1996-08-13 | Calgene, Inc. | Enhanced expression in a plant plastid |
| US5545818A (en) | 1994-03-11 | 1996-08-13 | Calgene Inc. | Expression of Bacillus thuringiensis cry proteins in plant plastids |
| ATE374821T1 (de) | 1997-02-20 | 2007-10-15 | Univ Johns Hopkins Med | Mutationen in atp-abhängigen transpositionsproteinen die die zielortspezifität reduzieren |
| WO1999005295A1 (en) | 1997-07-25 | 1999-02-04 | Thomas Jefferson University | Composition and method for targeted integration into cells |
| FI20030771A7 (fi) * | 2003-05-21 | 2004-11-22 | Helsingin Yliopisto | Menetelmä toksisten syanobakteerien määrittämiseksi |
| US7608434B2 (en) | 2004-08-04 | 2009-10-27 | Wisconsin Alumni Research Foundation | Mutated Tn5 transposase proteins and the use thereof |
| AU2008223544B2 (en) * | 2007-03-02 | 2014-06-05 | Dupont Nutrition Biosciences Aps | Cultures with improved phage resistance |
| US9080211B2 (en) | 2008-10-24 | 2015-07-14 | Epicentre Technologies Corporation | Transposon end compositions and methods for modifying nucleic acids |
| HUE041436T2 (hu) | 2009-12-10 | 2019-05-28 | Univ Minnesota | Tal-effektor-közvetített DNS-módosítás |
| US9109225B2 (en) * | 2012-09-14 | 2015-08-18 | New York University | Engineered transposon for facile construction of a random protein domain insertion library |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| WO2014194190A1 (en) | 2013-05-30 | 2014-12-04 | The Penn State Research Foundation | Gene targeting and genetic modification of plants via rna-guided genome editing |
| WO2015148680A1 (en) | 2014-03-25 | 2015-10-01 | Ginkgo Bioworks, Inc. | Methods and genetic systems for cell engineering |
| US10927384B2 (en) * | 2014-04-09 | 2021-02-23 | Dna Twopointo Inc. | DNA vectors, transposons and transposases for eukaryotic genome modification |
| AU2015294354B2 (en) * | 2014-07-21 | 2021-10-28 | Illumina, Inc. | Polynucleotide enrichment using CRISPR-Cas systems |
| WO2016025759A1 (en) | 2014-08-14 | 2016-02-18 | Shen Yuelei | Dna knock-in system |
| WO2016057951A2 (en) | 2014-10-09 | 2016-04-14 | Life Technologies Corporation | Crispr oligonucleotides and gene editing |
| EP3889260A1 (en) * | 2014-12-12 | 2021-10-06 | The Broad Institute, Inc. | Protected guide rnas (pgrnas) |
| KR20250171479A (ko) * | 2015-03-31 | 2025-12-08 | 소흠, 인코포레이티드 | 세포 또는 유기체의 게놈으로의 ＤＮＡ 서열의 표적화 혼입을 위한 Ｃａｓ 9 레트로바이러스 인테그라제 시스템 및 Ｃａｓ 9 재조합효소 시스템 |
| CN107667173A (zh) * | 2015-05-06 | 2018-02-06 | 斯尼普技术有限公司 | 改变微生物种群和改善微生物群 |
| KR20220139447A (ko) * | 2015-05-29 | 2022-10-14 | 노쓰 캐롤라이나 스테이트 유니버시티 | 크리스퍼 핵산을 사용하여 박테리아, 고세균, 조류 및 효모를 스크리닝하는 방법 |
| GB201514510D0 (en) * | 2015-08-14 | 2015-09-30 | Nemesis Bioscience Ltd | Delivery vehicle |
| US10004432B2 (en) | 2015-09-01 | 2018-06-26 | Qualcomm Incorporated | Pixel receiver with capacitance cancellation for ultrasonic imaging apparatus |
| US11091780B2 (en) * | 2015-09-18 | 2021-08-17 | The Regents Of The University Of California | Methods for autocatalytic genome editing and neutralizing autocatalytic genome editing and compositions thereof |
| CA3001312A1 (en) | 2015-10-08 | 2017-04-13 | Dna2.0, Inc. | Dna vectors, transposons and transposases for eukaryotic genome modification |
| AU2016371903B2 (en) * | 2015-12-16 | 2023-10-19 | Syngenta Crop Protection Ag | Genetic regions and genes associated with increased yield in plants |
| AU2016380351B2 (en) * | 2015-12-29 | 2023-04-06 | Monsanto Technology Llc | Novel CRISPR-associated transposases and uses thereof |
| GB201602473D0 (en) * | 2016-02-11 | 2016-03-30 | Horizon Discovery Ltd | Replicative transposon system |
| JOP20190166A1 (ar) | 2017-01-05 | 2019-07-02 | Univ Texas | استراتيجية مثلى من أجل تعديلات تخطي إكسون باستخدام crispr/cas9 مع متواليات توجيه ثلاثي |
| WO2018152244A1 (en) * | 2017-02-14 | 2018-08-23 | Seqwell, Inc. | Compositions and methods for sequencing nucleic acids |
| US20200377881A1 (en) * | 2017-03-24 | 2020-12-03 | President And Fellows Of Harvard College | Methods of Genome Engineering by Nuclease-Transposase Fusion Proteins |
| ES2980050T3 (es) * | 2017-06-08 | 2024-09-27 | Univ Osaka | Método para fabricar células eucariotas editadas con ADN |
| WO2019090175A1 (en) * | 2017-11-02 | 2019-05-09 | Arbor Biotechnologies, Inc. | Novel crispr-associated transposon systems and components |
| WO2019126774A1 (en) * | 2017-12-22 | 2019-06-27 | The Broad Institute, Inc. | Novel crispr enzymes and systems |
| CA3124110A1 (en) * | 2018-12-17 | 2020-06-25 | The Broad Institute, Inc. | Crispr-associated transposase systems and methods of use thereof |
| AU2020373064A1 (en) * | 2019-11-01 | 2022-05-26 | Massachusetts Institute Of Technology | Type I-B CRISPR-associated transposase systems |
-
2020
- 2020-03-06 CA CA3132197A patent/CA3132197A1/en active Pending
- 2020-03-06 SG SG11202109550TA patent/SG11202109550TA/en unknown
- 2020-03-06 EP EP20766573.8A patent/EP3935179A4/en active Pending
- 2020-03-06 BR BR112021017655A patent/BR112021017655A2/pt unknown
- 2020-03-06 AU AU2020232850A patent/AU2020232850B2/en active Active
- 2020-03-06 KR KR1020217032103A patent/KR20210149060A/ko active Pending
- 2020-03-06 JP JP2021552850A patent/JP7733576B2/ja active Active
- 2020-03-06 CN CN202080033551.1A patent/CN113795587A/zh active Pending
- 2020-03-06 WO PCT/US2020/021568 patent/WO2020181264A1/en not_active Ceased
- 2020-03-06 US US16/812,138 patent/US10947534B2/en active Active
- 2020-06-26 US US16/913,299 patent/US12331292B2/en active Active
-
2021
- 2021-09-02 IL IL286089A patent/IL286089A/en unknown
- 2021-09-06 ZA ZA2021/06516A patent/ZA202106516B/en unknown
-
2025
- 2025-05-08 US US19/202,829 patent/US20260109980A1/en active Pending