|
NL154598B
(nl)
|
1970-11-10 |
1977-09-15 |
Organon Nv |
Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
|
|
US3817837A
(en)
|
1971-05-14 |
1974-06-18 |
Syva Corp |
Enzyme amplification assay
|
|
US4018653A
(en)
|
1971-10-29 |
1977-04-19 |
U.S. Packaging Corporation |
Instrument for the detection of Neisseria gonorrhoeae without culture
|
|
US3939350A
(en)
|
1974-04-29 |
1976-02-17 |
Board Of Trustees Of The Leland Stanford Junior University |
Fluorescent immunoassay employing total reflection for activation
|
|
US3996345A
(en)
|
1974-08-12 |
1976-12-07 |
Syva Company |
Fluorescence quenching with immunological pairs in immunoassays
|
|
US4016043A
(en)
|
1975-09-04 |
1977-04-05 |
Akzona Incorporated |
Enzymatic immunological method for the determination of antigens and antibodies
|
|
US4437975A
(en)
|
1977-07-20 |
1984-03-20 |
Mobil Oil Corporation |
Manufacture of lube base stock oil
|
|
US4275149A
(en)
|
1978-11-24 |
1981-06-23 |
Syva Company |
Macromolecular environment control in specific receptor assays
|
|
US4277437A
(en)
|
1978-04-05 |
1981-07-07 |
Syva Company |
Kit for carrying out chemically induced fluorescence immunoassay
|
|
US4376110A
(en)
|
1980-08-04 |
1983-03-08 |
Hybritech, Incorporated |
Immunometric assays using monoclonal antibodies
|
|
US4486530A
(en)
|
1980-08-04 |
1984-12-04 |
Hybritech Incorporated |
Immunometric assays using monoclonal antibodies
|
|
US4366241A
(en)
|
1980-08-07 |
1982-12-28 |
Syva Company |
Concentrating zone method in heterogeneous immunoassays
|
|
US4424279A
(en)
|
1982-08-12 |
1984-01-03 |
Quidel |
Rapid plunger immunoassay method and apparatus
|
|
GB8311018D0
(en)
|
1983-04-22 |
1983-05-25 |
Amersham Int Plc |
Detecting mutations in dna
|
|
US4666828A
(en)
|
1984-08-15 |
1987-05-19 |
The General Hospital Corporation |
Test for Huntington's disease
|
|
US5242794A
(en)
|
1984-12-13 |
1993-09-07 |
Applied Biosystems, Inc. |
Detection of specific sequences in nucleic acids
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US5333675C1
(en)
|
1986-02-25 |
2001-05-01 |
Perkin Elmer Corp |
Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
|
|
US5656493A
(en)
|
1985-03-28 |
1997-08-12 |
The Perkin-Elmer Corporation |
System for automated performance of the polymerase chain reaction
|
|
US4965188A
(en)
|
1986-08-22 |
1990-10-23 |
Cetus Corporation |
Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
|
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
US4801531A
(en)
|
1985-04-17 |
1989-01-31 |
Biotechnology Research Partners, Ltd. |
Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
|
|
US4800159A
(en)
|
1986-02-07 |
1989-01-24 |
Cetus Corporation |
Process for amplifying, detecting, and/or cloning nucleic acid sequences
|
|
US4851331A
(en)
|
1986-05-16 |
1989-07-25 |
Allied Corporation |
Method and kit for polynucleotide assay including primer-dependant DNA polymerase
|
|
IL86724A
(en)
|
1987-06-19 |
1995-01-24 |
Siska Diagnostics Inc |
Methods and kits for amplification and testing of nucleic acid sequences
|
|
CA1340843C
(en)
|
1987-07-31 |
1999-12-07 |
J. Lawrence Burg |
Selective amplification of target polynucleotide sequences
|
|
JP2650159B2
(ja)
|
1988-02-24 |
1997-09-03 |
アクゾ・ノベル・エヌ・ベー |
核酸増幅方法
|
|
CA1340807C
(en)
|
1988-02-24 |
1999-11-02 |
Lawrence T. Malek |
Nucleic acid amplification process
|
|
IE61148B1
(en)
|
1988-03-10 |
1994-10-05 |
Ici Plc |
Method of detecting nucleotide sequences
|
|
US4988617A
(en)
|
1988-03-25 |
1991-01-29 |
California Institute Of Technology |
Method of detecting a nucleotide change in nucleic acids
|
|
US5137765A
(en)
|
1988-08-05 |
1992-08-11 |
Porton Instruments, Inc. |
Derivatized glass supports for peptide and protein sequencing
|
|
US5272057A
(en)
|
1988-10-14 |
1993-12-21 |
Georgetown University |
Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
|
|
CA2005589C
(en)
|
1988-12-16 |
2001-02-06 |
Akzo Nobel Nv |
Self-sustained, sequence replication system
|
|
US5856092A
(en)
|
1989-02-13 |
1999-01-05 |
Geneco Pty Ltd |
Detection of a nucleic acid sequence or a change therein
|
|
US5424186A
(en)
|
1989-06-07 |
1995-06-13 |
Affymax Technologies N.V. |
Very large scale immobilized polymer synthesis
|
|
US5242974A
(en)
|
1991-11-22 |
1993-09-07 |
Affymax Technologies N.V. |
Polymer reversal on solid surfaces
|
|
US5547839A
(en)
|
1989-06-07 |
1996-08-20 |
Affymax Technologies N.V. |
Sequencing of surface immobilized polymers utilizing microflourescence detection
|
|
US5800992A
(en)
|
1989-06-07 |
1998-09-01 |
Fodor; Stephen P.A. |
Method of detecting nucleic acids
|
|
US6346413B1
(en)
|
1989-06-07 |
2002-02-12 |
Affymetrix, Inc. |
Polymer arrays
|
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
US5744101A
(en)
|
1989-06-07 |
1998-04-28 |
Affymax Technologies N.V. |
Photolabile nucleoside protecting groups
|
|
US5527681A
(en)
|
1989-06-07 |
1996-06-18 |
Affymax Technologies N.V. |
Immobilized molecular synthesis of systematically substituted compounds
|
|
US5871928A
(en)
|
1989-06-07 |
1999-02-16 |
Fodor; Stephen P. A. |
Methods for nucleic acid analysis
|
|
US5925525A
(en)
|
1989-06-07 |
1999-07-20 |
Affymetrix, Inc. |
Method of identifying nucleotide differences
|
|
US5192659A
(en)
|
1989-08-25 |
1993-03-09 |
Genetype Ag |
Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
|
|
US5252743A
(en)
|
1989-11-13 |
1993-10-12 |
Affymax Technologies N.V. |
Spatially-addressable immobilization of anti-ligands on surfaces
|
|
US6013431A
(en)
|
1990-02-16 |
2000-01-11 |
Molecular Tool, Inc. |
Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
|
|
US5494810A
(en)
|
1990-05-03 |
1996-02-27 |
Cornell Research Foundation, Inc. |
Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
|
|
US5266222A
(en)
|
1990-05-23 |
1993-11-30 |
California Institute Of Technology |
Durable low surface-energy surfaces
|
|
DE69128545D1
(de)
|
1990-08-24 |
1998-02-05 |
Univ Tennessee Res Corp |
Technik des genetischen fingerabdrucks mit dns-vervielfältigung
|
|
WO1992007095A1
(en)
|
1990-10-15 |
1992-04-30 |
Stratagene |
Arbitrarily primed polymerase chain reaction method for fingerprinting genomes
|
|
US6004744A
(en)
|
1991-03-05 |
1999-12-21 |
Molecular Tool, Inc. |
Method for determining nucleotide identity through extension of immobilized primer
|
|
DE4214112A1
(de)
|
1991-08-02 |
1993-02-04 |
Europ Lab Molekularbiolog |
Neues verfahren zur sequenzierung von nukleinsaeuren
|
|
DE69233501T2
(de)
|
1991-11-22 |
2006-02-23 |
Affymetrix, Inc. (n.d.Ges.d.Staates Delaware), Santa Clara |
Kombinatorische Strategien für die Polymersynthese
|
|
US5550215A
(en)
|
1991-11-22 |
1996-08-27 |
Holmes; Christopher P. |
Polymer reversal on solid surfaces
|
|
US5412087A
(en)
|
1992-04-24 |
1995-05-02 |
Affymax Technologies N.V. |
Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces
|
|
US5384261A
(en)
|
1991-11-22 |
1995-01-24 |
Affymax Technologies N.V. |
Very large scale immobilized polymer synthesis using mechanically directed flow paths
|
|
US5324633A
(en)
|
1991-11-22 |
1994-06-28 |
Affymax Technologies N.V. |
Method and apparatus for measuring binding affinity
|
|
US5965362A
(en)
|
1992-03-04 |
1999-10-12 |
The Regents Of The University Of California |
Comparative genomic hybridization (CGH)
|
|
GB9208733D0
(en)
|
1992-04-22 |
1992-06-10 |
Medical Res Council |
Dna sequencing method
|
|
GB9211979D0
(en)
|
1992-06-05 |
1992-07-15 |
Buchard Ole |
Uses of nucleic acid analogues
|
|
US5605798A
(en)
|
1993-01-07 |
1997-02-25 |
Sequenom, Inc. |
DNA diagnostic based on mass spectrometry
|
|
CA2153387A1
(en)
|
1993-01-07 |
1994-07-21 |
Hubert Koester |
Dna sequencing by mass spectrometry
|
|
US6194144B1
(en)
|
1993-01-07 |
2001-02-27 |
Sequenom, Inc. |
DNA sequencing by mass spectrometry
|
|
US5491074A
(en)
|
1993-04-01 |
1996-02-13 |
Affymax Technologies Nv |
Association peptides
|
|
US5858659A
(en)
|
1995-11-29 |
1999-01-12 |
Affymetrix, Inc. |
Polymorphism detection
|
|
US5837832A
(en)
|
1993-06-25 |
1998-11-17 |
Affymetrix, Inc. |
Arrays of nucleic acid probes on biological chips
|
|
US6045996A
(en)
|
1993-10-26 |
2000-04-04 |
Affymetrix, Inc. |
Hybridization assays on oligonucleotide arrays
|
|
EP0765401B1
(en)
|
1993-11-17 |
2001-02-21 |
Amersham Pharmacia Biotech UK Limited |
Primer extension mass spectroscopy nucleic acid sequencing method
|
|
EP0754240B1
(en)
|
1994-02-07 |
2003-08-20 |
Beckman Coulter, Inc. |
Ligase/polymerase-mediated genetic bit analysis of single nucleotide polymorphisms and its use in genetic analysis
|
|
US5631734A
(en)
|
1994-02-10 |
1997-05-20 |
Affymetrix, Inc. |
Method and apparatus for detection of fluorescently labeled materials
|
|
US5578832A
(en)
|
1994-09-02 |
1996-11-26 |
Affymetrix, Inc. |
Method and apparatus for imaging a sample on a device
|
|
US6090555A
(en)
|
1997-12-11 |
2000-07-18 |
Affymetrix, Inc. |
Scanned image alignment systems and methods
|
|
AU693198B2
(en)
|
1994-04-25 |
1998-06-25 |
Avitech Diagnostics, Inc. |
Detection of mutation by resolvase cleavage
|
|
US5851770A
(en)
|
1994-04-25 |
1998-12-22 |
Variagenics, Inc. |
Detection of mismatches by resolvase cleavage using a magnetic bead support
|
|
WO1995030774A1
(en)
|
1994-05-05 |
1995-11-16 |
Beckman Instruments, Inc. |
Oligonucleotide repeat arrays
|
|
US5571639A
(en)
|
1994-05-24 |
1996-11-05 |
Affymax Technologies N.V. |
Computer-aided engineering system for design of sequence arrays and lithographic masks
|
|
US5834189A
(en)
|
1994-07-08 |
1998-11-10 |
Visible Genetics Inc. |
Method for evaluation of polymorphic genetic sequences, and the use thereof in identification of HLA types
|
|
US5795716A
(en)
|
1994-10-21 |
1998-08-18 |
Chee; Mark S. |
Computer-aided visualization and analysis system for sequence evaluation
|
|
US5959098A
(en)
|
1996-04-17 |
1999-09-28 |
Affymetrix, Inc. |
Substrate preparation process
|
|
US5599695A
(en)
|
1995-02-27 |
1997-02-04 |
Affymetrix, Inc. |
Printing molecular library arrays using deprotection agents solely in the vapor phase
|
|
US5624711A
(en)
|
1995-04-27 |
1997-04-29 |
Affymax Technologies, N.V. |
Derivatization of solid supports and methods for oligomer synthesis
|
|
DE19515552A1
(de)
|
1995-04-27 |
1996-10-31 |
Europ Lab Molekularbiolog |
Simultane Sequenzierung von Nukleinsäuren
|
|
US5545531A
(en)
|
1995-06-07 |
1996-08-13 |
Affymax Technologies N.V. |
Methods for making a device for concurrently processing multiple biological chip assays
|
|
US5981186A
(en)
|
1995-06-30 |
1999-11-09 |
Visible Genetics, Inc. |
Method and apparatus for DNA-sequencing using reduced number of sequencing mixtures
|
|
US5968740A
(en)
|
1995-07-24 |
1999-10-19 |
Affymetrix, Inc. |
Method of Identifying a Base in a Nucleic Acid
|
|
US5733729A
(en)
|
1995-09-14 |
1998-03-31 |
Affymetrix, Inc. |
Computer-aided probability base calling for arrays of nucleic acid probes on chips
|
|
JP3193301B2
(ja)
|
1995-09-14 |
2001-07-30 |
麒麟麦酒株式会社 |
生理活性タンパク質ｐ１６０
|
|
US5869242A
(en)
|
1995-09-18 |
1999-02-09 |
Myriad Genetics, Inc. |
Mass spectrometry to assess DNA sequence polymorphisms
|
|
US6147205A
(en)
|
1995-12-15 |
2000-11-14 |
Affymetrix, Inc. |
Photocleavable protecting groups and methods for their use
|
|
US6114122A
(en)
|
1996-03-26 |
2000-09-05 |
Affymetrix, Inc. |
Fluidics station with a mounting system and method of using
|
|
US5928906A
(en)
|
1996-05-09 |
1999-07-27 |
Sequenom, Inc. |
Process for direct sequencing during template amplification
|
|
WO1997043611A1
(en)
|
1996-05-16 |
1997-11-20 |
Affymetrix, Inc. |
Systems and methods for detection of labeled materials
|
|
US5786146A
(en)
|
1996-06-03 |
1998-07-28 |
The Johns Hopkins University School Of Medicine |
Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
|
|
EP0912752A1
(en)
|
1996-06-14 |
1999-05-06 |
Sarnoff Corporation |
Method for polynucleotide sequencing
|
|
GB9620209D0
(en)
|
1996-09-27 |
1996-11-13 |
Cemu Bioteknik Ab |
Method of sequencing DNA
|
|
US6017702A
(en)
|
1996-12-05 |
2000-01-25 |
The Perkin-Elmer Corporation |
Chain-termination type nucleic acid sequencing method including 2'-deoxyuridine-5'-triphosphate
|
|
US5876934A
(en)
|
1996-12-18 |
1999-03-02 |
Pharmacia Biotech Inc. |
DNA sequencing method
|
|
US6046005A
(en)
|
1997-01-15 |
2000-04-04 |
Incyte Pharmaceuticals, Inc. |
Nucleic acid sequencing with solid phase capturable terminators comprising a cleavable linking group
|
|
US6586806B1
(en)
|
1997-06-20 |
2003-07-01 |
Cypress Semiconductor Corporation |
Method and structure for a single-sided non-self-aligned transistor
|
|
US6420108B2
(en)
|
1998-02-09 |
2002-07-16 |
Affymetrix, Inc. |
Computer-aided display for comparative gene expression
|
|
JP2001515234A
(ja)
|
1997-07-25 |
2001-09-18 |
アフィメトリックス インコーポレイテッド |
多型性データベースを提供するためのシステム
|
|
US6223127B1
(en)
|
1997-08-15 |
2001-04-24 |
Affymetrix, Inc. |
Polymorphism detection utilizing clustering analysis
|
|
EP1027456B1
(en)
|
1997-10-31 |
2005-03-16 |
Affymetrix, Inc. (a Delaware Corporation) |
Expression profiles in adult and fetal organs
|
|
US5998143A
(en)
|
1997-12-05 |
1999-12-07 |
The Perkin-Elmer Corporation |
Cycle sequencing thermal profiles
|
|
US6201639B1
(en)
|
1998-03-20 |
2001-03-13 |
James W. Overbeck |
Wide field of view and high speed scanning microscopy
|
|
US6269846B1
(en)
|
1998-01-13 |
2001-08-07 |
Genetic Microsystems, Inc. |
Depositing fluid specimens on substrates, resulting ordered arrays, techniques for deposition of arrays
|
|
US6428752B1
(en)
|
1998-05-14 |
2002-08-06 |
Affymetrix, Inc. |
Cleaning deposit devices that form microarrays and the like
|
|
AU753273B2
(en)
|
1998-02-04 |
2002-10-10 |
Variagenics, Inc. |
Mismatch detection techniques
|
|
US6185030B1
(en)
|
1998-03-20 |
2001-02-06 |
James W. Overbeck |
Wide field of view and high speed scanning microscopy
|
|
US5936324A
(en)
|
1998-03-30 |
1999-08-10 |
Genetic Microsystems Inc. |
Moving magnet scanner
|
|
US7805388B2
(en)
*
|
1998-05-01 |
2010-09-28 |
Health Discovery Corporation |
Method for feature selection in a support vector machine using feature ranking
|
|
US6183958B1
(en)
|
1998-05-06 |
2001-02-06 |
Variagenics, Inc. |
Probes for variance detection
|
|
JP3565025B2
(ja)
|
1998-07-07 |
2004-09-15 |
日産自動車株式会社 |
治具交換装置および治具交換方法
|
|
US6185561B1
(en)
|
1998-09-17 |
2001-02-06 |
Affymetrix, Inc. |
Method and apparatus for providing and expression data mining database
|
|
US6140054A
(en)
|
1998-09-30 |
2000-10-31 |
University Of Utah Research Foundation |
Multiplex genotyping using fluorescent hybridization probes
|
|
US6262216B1
(en)
|
1998-10-13 |
2001-07-17 |
Affymetrix, Inc. |
Functionalized silicon compounds and methods for their synthesis and use
|
|
WO2000024939A1
(en)
|
1998-10-27 |
2000-05-04 |
Affymetrix, Inc. |
Complexity management and analysis of genomic dna
|
|
US7700324B1
(en)
|
1998-11-03 |
2010-04-20 |
The Johns Hopkins University School Of Medicine |
Methylated CpG island amplification (MCA)
|
|
NO986133D0
(no)
|
1998-12-23 |
1998-12-23 |
Preben Lexow |
FremgangsmÕte for DNA-sekvensering
|
|
EP1165839A2
(en)
|
1999-03-26 |
2002-01-02 |
Whitehead Institute For Biomedical Research |
Universal arrays
|
|
US6218803B1
(en)
|
1999-06-04 |
2001-04-17 |
Genetic Microsystems, Inc. |
Position sensing with variable capacitance transducers
|
|
US6300070B1
(en)
|
1999-06-04 |
2001-10-09 |
Mosaic Technologies, Inc. |
Solid phase methods for amplifying multiple nucleic acids
|
|
US6811668B1
(en)
|
1999-06-22 |
2004-11-02 |
Caliper Life Sciences, Inc. |
Apparatus for the operation of a microfluidic device
|
|
IL147302A0
(en)
|
1999-06-28 |
2002-08-14 |
California Inst Of Techn |
Microfabricated elastomeric valve and pump systems
|
|
US6274320B1
(en)
|
1999-09-16 |
2001-08-14 |
Curagen Corporation |
Method of sequencing a nucleic acid
|
|
US6297016B1
(en)
|
1999-10-08 |
2001-10-02 |
Applera Corporation |
Template-dependent ligation with PNA-DNA chimeric probes
|
|
US6221600B1
(en)
|
1999-10-08 |
2001-04-24 |
Board Of Regents, The University Of Texas System |
Combinatorial oligonucleotide PCR: a method for rapid, global expression analysis
|
|
WO2001027327A2
(en)
|
1999-10-08 |
2001-04-19 |
Protogene Laboratories, Inc. |
Method and apparatus for performing large numbers of reactions using array assembly
|
|
US6958225B2
(en)
|
1999-10-27 |
2005-10-25 |
Affymetrix, Inc. |
Complexity management of genomic DNA
|
|
US7970718B2
(en)
*
|
2001-05-18 |
2011-06-28 |
Health Discovery Corporation |
Method for feature selection and for evaluating features identified as significant for classifying data
|
|
WO2001051918A1
(en)
|
2000-01-12 |
2001-07-19 |
Ut-Battelle, Llc |
A microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream
|
|
US7452713B2
(en)
|
2000-02-29 |
2008-11-18 |
Stmicroelectronics S.R.L. |
Process for manufacturing a microfluidic device with buried channels
|
|
US7867763B2
(en)
|
2004-01-25 |
2011-01-11 |
Fluidigm Corporation |
Integrated chip carriers with thermocycler interfaces and methods of using the same
|
|
SE0001768D0
(sv)
|
2000-05-12 |
2000-05-12 |
Helen Andersson |
Mikrofluidisk flödescell för manipulering av partiklar
|
|
US6386749B1
(en)
|
2000-06-26 |
2002-05-14 |
Affymetrix, Inc. |
Systems and methods for heating and mixing fluids
|
|
EP1340082A2
(en)
|
2000-08-23 |
2003-09-03 |
Imego AB |
Microfluidic device and method with transport of magnetic particles into and out of wells
|
|
US20020048821A1
(en)
|
2000-08-24 |
2002-04-25 |
David Storek |
Sample preparing arrangement and a method relating to such an arrangement
|
|
ATE365922T1
(de)
|
2000-10-27 |
2007-07-15 |
Mount Sinai Hospital Corp |
Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6)
|
|
WO2002056049A2
(en)
|
2000-12-01 |
2002-07-18 |
Protasis Corp |
Microfluidic device with multiple microcoil nmr detectors
|
|
US6391592B1
(en)
|
2000-12-14 |
2002-05-21 |
Affymetrix, Inc. |
Blocker-aided target amplification of nucleic acids
|
|
US20020183936A1
(en)
|
2001-01-24 |
2002-12-05 |
Affymetrix, Inc. |
Method, system, and computer software for providing a genomic web portal
|
|
US7323140B2
(en)
|
2001-03-28 |
2008-01-29 |
Handylab, Inc. |
Moving microdroplets in a microfluidic device
|
|
US6802342B2
(en)
|
2001-04-06 |
2004-10-12 |
Fluidigm Corporation |
Microfabricated fluidic circuit elements and applications
|
|
US6649348B2
(en)
|
2001-06-29 |
2003-11-18 |
Agilent Technologies Inc. |
Methods for manufacturing arrays
|
|
US6585606B2
(en)
|
2001-07-16 |
2003-07-01 |
Thomas S. Penrose |
Golf club accessory
|
|
US6632611B2
(en)
|
2001-07-20 |
2003-10-14 |
Affymetrix, Inc. |
Method of target enrichment and amplification
|
|
US7390463B2
(en)
|
2001-09-07 |
2008-06-24 |
Corning Incorporated |
Microcolumn-based, high-throughput microfluidic device
|
|
ATE477054T1
(de)
|
2001-09-17 |
2010-08-15 |
Gyros Patent Ab |
Einen kontrollierten strom in einer mikrofluidvorrichtung ermöglichende funktionseinheit
|
|
US7189580B2
(en)
|
2001-10-19 |
2007-03-13 |
Wisconsin Alumni Research Foundation |
Method of pumping fluid through a microfluidic device
|
|
US7253003B2
(en)
|
2001-10-19 |
2007-08-07 |
Wisconsin Alumni Research Foundation |
Method for monitoring the environment within a microfluidic device
|
|
US7118910B2
(en)
|
2001-11-30 |
2006-10-10 |
Fluidigm Corporation |
Microfluidic device and methods of using same
|
|
US7258837B2
(en)
|
2001-12-05 |
2007-08-21 |
University Of Washington |
Microfluidic device and surface decoration process for solid phase affinity binding assays
|
|
US7238255B2
(en)
|
2001-12-31 |
2007-07-03 |
Gyros Patent Ab |
Microfluidic device and its manufacture
|
|
US6958119B2
(en)
|
2002-02-26 |
2005-10-25 |
Agilent Technologies, Inc. |
Mobile phase gradient generation microfluidic device
|
|
US7195986B1
(en)
|
2002-03-08 |
2007-03-27 |
Caliper Life Sciences, Inc. |
Microfluidic device with controlled substrate conductivity
|
|
GB2388189B
(en)
|
2002-04-29 |
2006-01-11 |
Robert Jeffrey Geddes Carr |
Optical detection and analysis of particles
|
|
US7189581B2
(en)
|
2002-04-30 |
2007-03-13 |
Wisconsin Alumni Research Foundation |
Method of obtaining a sample concentration of a solution in a microfluidic device
|
|
DE60228685D1
(de)
|
2002-05-16 |
2008-10-16 |
Micronit Microfluidics Bv |
Verfahren zur Herstellung eines mikrofluidischen Bauteiles
|
|
US7381471B2
(en)
|
2002-07-15 |
2008-06-03 |
University Of Virginia Patent Foundation |
Hybrid polymers for functional tuning of microfluidic device surfaces
|
|
US7201881B2
(en)
|
2002-07-26 |
2007-04-10 |
Applera Corporation |
Actuator for deformable valves in a microfluidic device, and method
|
|
US7135147B2
(en)
|
2002-07-26 |
2006-11-14 |
Applera Corporation |
Closing blade for deformable valve in a microfluidic device and method
|
|
US7452509B2
(en)
|
2002-07-26 |
2008-11-18 |
Applied Biosystems Inc. |
Microfluidic device including displaceable material trap, and system
|
|
WO2004011666A2
(en)
|
2002-07-26 |
2004-02-05 |
Applera Corporation |
Mg-mediated hot start biochemical reactions
|
|
KR100480338B1
(ko)
|
2002-08-08 |
2005-03-30 |
한국전자통신연구원 |
극소량의 유체제어를 위한 미세 유체제어소자
|
|
TW536524B
(en)
|
2002-09-17 |
2003-06-11 |
Fan-Gen Tzeng |
Network-type micro-channel device for micro-fluid
|
|
US7118661B2
(en)
|
2002-09-30 |
2006-10-10 |
The Regents Of The University Of California |
Nanolaminate microfluidic device for mobility selection of particles
|
|
EP2719756B1
(en)
|
2002-10-04 |
2017-04-05 |
The Regents of the University of California |
Microfluidic multi-compartment device for neuroscience research
|
|
FR2848125B1
(fr)
|
2002-12-04 |
2006-06-09 |
Commissariat Energie Atomique |
Dispositif microfluidique dans lequel l'interface liquide/fluide est stabilisee
|
|
US7467928B2
(en)
|
2002-12-12 |
2008-12-23 |
Board Of Trustees Of The University Of Arkansas |
Microfluidic device utilizing magnetohydrodynamics and method for fabrication thereof
|
|
US7125711B2
(en)
|
2002-12-19 |
2006-10-24 |
Bayer Healthcare Llc |
Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
|
|
US7338637B2
(en)
|
2003-01-31 |
2008-03-04 |
Hewlett-Packard Development Company, L.P. |
Microfluidic device with thin-film electronic devices
|
|
US7413709B2
(en)
|
2003-02-12 |
2008-08-19 |
Agilent Technologies, Inc. |
PAEK-based microfluidic device with integrated electrospray emitter
|
|
JP3856763B2
(ja)
|
2003-03-11 |
2006-12-13 |
財団法人川村理化学研究所 |
マイクロ流体素子の製造方法
|
|
AU2004228678A1
(en)
|
2003-04-03 |
2004-10-21 |
Fluidigm Corp. |
Microfluidic devices and methods of using same
|
|
US20070117164A1
(en)
|
2003-04-08 |
2007-05-24 |
Raskov Hans H |
Method for detection of colorectal cancer in human samples
|
|
US7422725B2
(en)
|
2003-05-01 |
2008-09-09 |
Enplas Corporation |
Sample handling unit applicable to microchip, and microfluidic device having microchips
|
|
US7544506B2
(en)
|
2003-06-06 |
2009-06-09 |
Micronics, Inc. |
System and method for heating, cooling and heat cycling on microfluidic device
|
|
US20050124071A1
(en)
|
2003-09-30 |
2005-06-09 |
Kraus Virginia B. |
Methods and compositions for diagnosing musculoskeletal, arthritic and joint disorders by biomarker dating
|
|
FR2862007B1
(fr)
|
2003-11-12 |
2005-12-23 |
Commissariat Energie Atomique |
Dispositif microfluidique muni d'un nez d'electronebulisation.
|
|
US7329391B2
(en)
|
2003-12-08 |
2008-02-12 |
Applera Corporation |
Microfluidic device and material manipulating method using same
|
|
EP1547688A1
(en)
|
2003-12-23 |
2005-06-29 |
STMicroelectronics S.r.l. |
Microfluidic device and method of locally concentrating electrically charged substances in a microfluidic device
|
|
US7099778B2
(en)
|
2003-12-30 |
2006-08-29 |
Caliper Life Sciences, Inc. |
Method for determining diffusivity and molecular weight in a microfluidic device
|
|
US7351380B2
(en)
|
2004-01-08 |
2008-04-01 |
Sandia Corporation |
Microfluidic structures and methods for integrating a functional component into a microfluidic device
|
|
US7250260B2
(en)
|
2004-02-18 |
2007-07-31 |
Applera Corporation |
Multi-step bioassays on modular microfluidic application platforms
|
|
US20060195266A1
(en)
*
|
2005-02-25 |
2006-08-31 |
Yeatman Timothy J |
Methods for predicting cancer outcome and gene signatures for use therein
|
|
US7402229B2
(en)
|
2004-03-31 |
2008-07-22 |
Intel Corporation |
Fabrication and use of semipermeable membranes and gels for the control of electrolysis in a microfluidic device
|
|
US7575722B2
(en)
|
2004-04-02 |
2009-08-18 |
Eksigent Technologies, Inc. |
Microfluidic device
|
|
US7419639B2
(en)
|
2004-05-12 |
2008-09-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Multilayer microfluidic device
|
|
US7655479B2
(en)
|
2004-06-30 |
2010-02-02 |
University Of South Florida |
Luminescence characterization of quantum dots conjugated with biomarkers for early cancer detection
|
|
JP2008505649A
(ja)
|
2004-07-09 |
2008-02-28 |
アモークス リミテッド |
免疫細胞バイオセンサーおよびその使用方法
|
|
US7488596B2
(en)
|
2004-12-17 |
2009-02-10 |
Samsung Electronics Co., Ltd. |
Microfluidic device comprising electrolysis device for cell lysis and method for electrochemically lysing cells using the same
|
|
WO2006084132A2
(en)
|
2005-02-01 |
2006-08-10 |
Agencourt Bioscience Corp. |
Reagents, methods, and libraries for bead-based squencing
|
|
WO2006115863A2
(en)
|
2005-04-12 |
2006-11-02 |
Caliper Life Sciences, Inc. |
Compact optical detection system for microfluidic devices
|
|
US20090061422A1
(en)
*
|
2005-04-19 |
2009-03-05 |
Linke Steven P |
Diagnostic markers of breast cancer treatment and progression and methods of use thereof
|
|
KR100590581B1
(ko)
|
2005-05-10 |
2006-06-19 |
삼성전자주식회사 |
미세유동장치 및 그 제조방법
|
|
JP4992201B2
(ja)
|
2005-06-07 |
2012-08-08 |
富士ゼロックス株式会社 |
マイクロ流体制御方法、マイクロ流体素子およびその製造方法
|
|
WO2007002069A2
(en)
|
2005-06-21 |
2007-01-04 |
Anthony Goncalves |
Serum biomarkers for breast cancer
|
|
CA2672322A1
(en)
|
2005-10-14 |
2007-04-19 |
Institut De Cardiologie De Montreal |
Method for detecting a biomarker of oxidative stress in a biological sample
|
|
US7993859B2
(en)
|
2005-10-14 |
2011-08-09 |
Institut De Cardiologie De Montreal |
Method for quantifying oxidative stress caused by different biological pathways
|
|
TWI274040B
(en)
|
2005-12-23 |
2007-02-21 |
Ind Tech Res Inst |
Microfluidic device and method of manufacturing the same
|
|
US7568399B2
(en)
|
2006-01-05 |
2009-08-04 |
Integrated Sensing Systems, Inc. |
Microfluidic device
|
|
US7581429B2
(en)
|
2006-01-06 |
2009-09-01 |
Integrated Sensing Systems, Inc. |
Microfluidic device and method of operation
|
|
ATE486285T1
(de)
|
2006-01-31 |
2010-11-15 |
Medical Res Fund Of Tel Aviv S |
Verfahren zur früherkennung von krebs
|
|
CN101495654A
(zh)
|
2006-04-19 |
2009-07-29 |
阿普里拉股份有限公司 |
无凝胶珠基测序的试剂、方法和文库
|
|
CN103424541B
(zh)
|
2006-05-18 |
2018-01-30 |
分子压型学会股份有限公司 |
确定针对病状的个性化医疗介入的系统和方法
|
|
US8768629B2
(en)
*
|
2009-02-11 |
2014-07-01 |
Caris Mpi, Inc. |
Molecular profiling of tumors
|
|
US20100184027A1
(en)
|
2006-07-13 |
2010-07-22 |
Epigenomics Ag |
Methods and nucleic acids for analyses of cellular proliferative disorders
|
|
WO2008014458A2
(en)
|
2006-07-27 |
2008-01-31 |
Ludwig Institute For Cancer Research |
Protein markers for the diagnosis and prognosis of ovarian and breast cancer
|
|
DK2089722T3
(en)
|
2006-09-07 |
2018-01-22 |
Otago Innovation Ltd |
BIOMARKET FOR EARLY DETECTION OF ACUTE HEART DISORDERS
|
|
GB0700374D0
(en)
|
2007-01-09 |
2007-02-14 |
Oncomethylome Sciences S A |
NDRG family methylation markers
|
|
US20080280768A1
(en)
*
|
2007-01-30 |
2008-11-13 |
Oncotech, Inc. |
Reagents and Methods for Predicting Drug Resistance
|
|
WO2008130516A1
(en)
|
2007-04-11 |
2008-10-30 |
Manel Esteller |
Epigenetic biomarkers for early detection, therapeutic effectiveness, and relapse monitoring of cancer
|
|
US20100222230A1
(en)
|
2007-04-11 |
2010-09-02 |
The General Hospital Corporation |
Diagnostic and prognostic methods for renal cell carcinoma
|
|
US8664358B2
(en)
|
2007-06-29 |
2014-03-04 |
Vermillion, Inc. |
Predictive markers for ovarian cancer
|
|
CA2705952C
(en)
|
2007-11-23 |
2018-05-01 |
British Columbia Cancer Agency Branch |
Methods for detecting lung cancer and monitoring treatment response
|
|
EA018974B9
(ru)
|
2008-02-05 |
2014-04-30 |
Харбор Терапьютикс, Инк. |
Твердые лекарственные формы
|
|
EP2245568A4
(en)
*
|
2008-02-20 |
2012-12-05 |
Univ Mcmaster |
EXPERIMENTAL SYSTEM FOR DETERMINING THE RESPONSE OF PATIENTS TO TREATMENT
|
|
US7745150B2
(en)
|
2008-03-07 |
2010-06-29 |
The University Of Connecticut |
Methods for the detection and monitoring of congestive heart failure
|
|
EP2265642A4
(en)
|
2008-03-12 |
2012-05-02 |
Otago Innovation Ltd |
BIOMARKERS
|
|
WO2009134420A2
(en)
|
2008-05-01 |
2009-11-05 |
The Salk Institute For Biological Studies |
Epigenetic silencing of tumor suppressor genes
|
|
CN102084366A
(zh)
*
|
2008-05-12 |
2011-06-01 |
皇家飞利浦电子股份有限公司 |
医学分析系统
|
|
CN102232117A
(zh)
|
2008-10-14 |
2011-11-02 |
卡里斯Mpi公司 |
描绘肿瘤类型生物标志模式和特征集的基因靶和基因表达的蛋白靶
|
|
EP2358912B1
(en)
|
2008-10-30 |
2016-10-12 |
Caris Life Sciences Switzerland Holdings GmbH |
Methods for assessing rna patterns
|
|
GB2463401B
(en)
|
2008-11-12 |
2014-01-29 |
Caris Life Sciences Luxembourg Holdings S A R L |
Characterizing prostate disorders by analysis of microvesicles
|
|
WO2011109440A1
(en)
|
2010-03-01 |
2011-09-09 |
Caris Life Sciences Luxembourg Holdings |
Biomarkers for theranostics
|
|
EP2202522A1
(en)
|
2008-12-23 |
2010-06-30 |
Universiteit Leiden |
Methods for immobilizing microvesicles, means and methods for detecting them, and uses thereof
|
|
IL313131A
(en)
|
2009-02-11 |
2024-07-01 |
Caris Mpi Inc |
Molecular characterization of tumors
|
|
EP2421987A4
(en)
|
2009-06-19 |
2012-10-31 |
Wayne John Cancer Inst |
USE OF THE METHYLATION STATUS OF MINT-LOCI AS MARKER FOR RECTAL CARCINOMAS
|
|
CA2779223A1
(en)
|
2009-10-27 |
2011-05-12 |
Caris Mpi, Inc. |
Molecular profiling for personalized medicine
|
|
US8765713B2
(en)
*
|
2009-10-30 |
2014-07-01 |
Keio University |
Method for determination of sensitivity to anti-cancer agent
|
|
CA2782284A1
(en)
|
2009-11-30 |
2011-06-03 |
Caris Life Sciences Luxembourg Holdings, S.A.R.L. |
Methods and systems for isolating, storing, and analyzing vesicles
|
|
US20140148348A1
(en)
|
2010-01-13 |
2014-05-29 |
Christine Kuslich |
Dectection of gastrointestinal disorders
|
|
WO2011127219A1
(en)
|
2010-04-06 |
2011-10-13 |
Caris Life Sciences Luxembourg Holdings |
Circulating biomarkers for disease
|
|
EP2564340B1
(en)
*
|
2010-04-29 |
2020-01-08 |
The Regents of The University of California |
Pathway recognition algorithm using data integration on genomic models (paradigm)
|
|
BR112013013656B1
(pt)
|
2010-12-03 |
2021-01-26 |
Kabushiki Kaisha Yakult Honsha |
processo para determinação da sensibilidade de um indivíduo a um agente anticâncer, kit para realização do dito processo bem como processo de triagem para um agente de aperfeiçoamento de sensibilidade a um agente anticâncer
|
|
AU2011352167A1
(en)
|
2010-12-28 |
2013-07-11 |
Caris Mpi, Inc. |
Molecular profiling for cancer
|
|
CN103403187A
(zh)
|
2011-01-18 |
2013-11-20 |
艾沃锐斯特基因有限公司 |
结肠直肠癌复发的预后特征
|
|
US9797884B2
(en)
*
|
2011-03-24 |
2017-10-24 |
Keio University |
Marker for determination of sensitivity to anticancer agent
|
|
EP3825693A1
(en)
*
|
2011-04-29 |
2021-05-26 |
Cancer Prevention And Cure, Ltd. |
Methods of identification and diagnosis of lung diseases using classification systems and kits thereof
|
|
CA2838736A1
(en)
|
2011-06-07 |
2012-12-13 |
Caris Mpi, Inc. |
Molecular profiling for cancer
|
|
GB201215944D0
(en)
*
|
2012-09-06 |
2012-10-24 |
Univ Manchester |
Image processing apparatus and method for fittng a deformable shape model to an image using random forests
|
|
EP2929350A4
(en)
|
2012-12-04 |
2016-11-16 |
Caris Mpi Inc |
MOLECULAR PROFILING OF CANCER
|
|
US20140229544A1
(en)
|
2013-02-12 |
2014-08-14 |
BackPeddle, LLC |
Sharing content in social networks
|
|
ITPD20130240A1
(it)
|
2013-09-02 |
2015-03-03 |
Optimae Srl |
Metodo per la produzione di aste di occhiali in materiale composito a rigidità differenziata ed asta per occhiali ottenuta in accordo con tale metodo
|
|
EP2876167A1
(en)
*
|
2013-11-21 |
2015-05-27 |
Institut Gustave Roussy |
Microbiota composition, as a marker of responsiveness to chemotherapy, and use of microbial modulators (pre-,pro- or synbiotics) for improving the efficacy of a cancer treatment
|
|
FR3016461B1
(fr)
|
2014-01-10 |
2017-06-23 |
Imabiotech |
Procede de traitement de donnees d'imagerie moleculaire et serveur de donnees correspondant
|
|
WO2015116868A2
(en)
|
2014-01-29 |
2015-08-06 |
Caris Mpi, Inc. |
Molecular profiling of immune modulators
|
|
GB201405715D0
(en)
|
2014-03-31 |
2014-05-14 |
Abo Hamed Enass |
Methods, apparatus and materials
|
|
EP3155758A4
(en)
*
|
2014-06-10 |
2018-04-11 |
Sightline Innovation Inc. |
System and method for network based application development and implementation
|
|
US10570457B2
(en)
*
|
2014-09-26 |
2020-02-25 |
Medical Prognosis Institute A/S |
Methods for predicting drug responsiveness
|
|
WO2016094330A2
(en)
*
|
2014-12-08 |
2016-06-16 |
20/20 Genesystems, Inc |
Methods and machine learning systems for predicting the liklihood or risk of having cancer
|
|
WO2016141169A1
(en)
|
2015-03-03 |
2016-09-09 |
Caris Mpi, Inc. |
Molecular profiling for cancer
|
|
CN106252749B
(zh)
|
2015-06-04 |
2020-12-29 |
松下知识产权经营株式会社 |
蓄电池包的控制方法以及蓄电池包
|
|
IL258309B2
(en)
|
2015-09-24 |
2023-03-01 |
Caris Science Inc |
Method, device and product of computer software for analyzing biological data
|
|
US20170132362A1
(en)
*
|
2015-11-09 |
2017-05-11 |
Washington State University |
Novel machine learning approach for the identification of genomic features associated with epigenetic control regions and transgenerational inheritance of epimutations
|
|
US20170175169A1
(en)
*
|
2015-12-18 |
2017-06-22 |
Min Lee |
Clinical decision support system utilizing deep neural networks for diagnosis of chronic diseases
|
|
US10065868B2
(en)
|
2016-03-28 |
2018-09-04 |
Saudi Arabian Oil Company |
Coupling photovoltaic and concentrated solar power technologies for desalination
|
|
US11621057B2
(en)
*
|
2016-04-08 |
2023-04-04 |
Biodesix, Inc. |
Classifier generation methods and predictive test for ovarian cancer patient prognosis under platinum chemotherapy
|
|
AU2017278261A1
(en)
|
2016-06-05 |
2019-01-31 |
Berg Llc |
Systems and methods for patient stratification and identification of potential biomarkers
|
|
US10328872B2
(en)
|
2016-06-29 |
2019-06-25 |
Hamilton Sundstrand Corporation |
Methodology for simplification of aircraft harnessing in multi-redundant control systems
|
|
US10350280B2
(en)
*
|
2016-08-31 |
2019-07-16 |
Medgenome Inc. |
Methods to analyze genetic alterations in cancer to identify therapeutic peptide vaccines and kits therefore
|
|
MX2019002731A
(es)
|
2016-09-08 |
2019-10-02 |
Curematch Inc |
Optimizacion de opciones terapeuticas en medicina perzonalizada.
|
|
KR101936465B1
(ko)
|
2016-09-21 |
2019-01-08 |
현대자동차주식회사 |
배터리 충전 시스템 및 방법
|
|
US20180089373A1
(en)
*
|
2016-09-23 |
2018-03-29 |
Driver, Inc. |
Integrated systems and methods for automated processing and analysis of biological samples, clinical information processing and clinical trial matching
|
|
WO2018078142A1
(en)
*
|
2016-10-28 |
2018-05-03 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Means and methods for determining efficacy of fluorouracil (5-fu) in colorectal cancer (crc) therapy
|
|
AU2017258901A1
(en)
*
|
2016-12-30 |
2018-07-19 |
Allarity Therapeutics Europe ApS |
Methods for predicting drug responsiveness in cancer patients
|
|
WO2018146034A1
(en)
|
2017-02-07 |
2018-08-16 |
F. Hoffmann-La Roche Ag |
Non-invasive test to predict response to therapy in colorectal cancer patients
|
|
WO2018146033A1
(en)
|
2017-02-07 |
2018-08-16 |
F. Hoffmann-La Roche Ag |
Non-invasive test to predict recurrence of colorectal cancer
|
|
US11618926B2
(en)
|
2017-02-28 |
2023-04-04 |
Baylor Research Institute |
Methods for diagnosing, prognosing, and treating colorectal cancer using biomarker expression
|
|
US20200024669A1
(en)
*
|
2017-03-20 |
2020-01-23 |
Caris Mpi, Inc. |
Genomic stability profiling
|
|
CN116148481A
(zh)
*
|
2017-03-31 |
2023-05-23 |
学校法人庆应义塾 |
并用抗癌剂的感受性判定标记
|
|
US11392827B1
(en)
*
|
2017-07-19 |
2022-07-19 |
United States Of America As Represented By The Secretary Of The Navy |
Deeper learning from the real-time transformative correction of and reasoning from neural network outputs
|
|
US10679129B2
(en)
*
|
2017-09-28 |
2020-06-09 |
D5Ai Llc |
Stochastic categorical autoencoder network
|
|
US11708600B2
(en)
*
|
2017-10-05 |
2023-07-25 |
Decode Health, Inc. |
Long non-coding RNA gene expression signatures in disease diagnosis
|
|
US20190317079A1
(en)
*
|
2017-10-16 |
2019-10-17 |
Sightline Innovation Inc. |
System and method for volatile organic compound detection
|
|
US11250345B1
(en)
*
|
2018-06-08 |
2022-02-15 |
Intuit Inc. |
Methods for identifying transactions with user location information
|
|
US11120364B1
(en)
*
|
2018-06-14 |
2021-09-14 |
Amazon Technologies, Inc. |
Artificial intelligence system with customizable training progress visualization and automated recommendations for rapid interactive development of machine learning models
|
|
US10423403B1
(en)
|
2018-11-29 |
2019-09-24 |
Capital One Services, Llc |
Utilizing a machine learning model to predict metrics for an application development process
|
|
JP7462632B2
(ja)
|
2018-11-30 |
2024-04-05 |
カリス エムピーアイ インコーポレイテッド |
次世代分子プロファイリング
|
|
CA3140365A1
(en)
|
2019-05-14 |
2020-11-19 |
Tempus Labs, Inc. |
Systems and methods for multi-label cancer classification
|
|
US10734096B1
(en)
|
2019-11-29 |
2020-08-04 |
Kpn Innovations, Llc |
Methods and systems for optimizing supplement decisions
|
|
WO2021112918A1
(en)
|
2019-12-02 |
2021-06-10 |
Caris Mpi, Inc. |
Pan-cancer platinum response predictor
|
|
AU2022249074A1
(en)
*
|
2021-03-31 |
2023-09-21 |
PrognomIQ, Inc. |
Multi-omic assessment
|