JP2021530225A5 - - Google Patents
Info
- Publication number
- JP2021530225A5 JP2021530225A5 JP2021500804A JP2021500804A JP2021530225A5 JP 2021530225 A5 JP2021530225 A5 JP 2021530225A5 JP 2021500804 A JP2021500804 A JP 2021500804A JP 2021500804 A JP2021500804 A JP 2021500804A JP 2021530225 A5 JP2021530225 A5 JP 2021530225A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- lamb1
- endogenous
- endogenous protein
- gene encoding
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024139532A JP2024161560A (ja) | 2018-07-13 | 2024-08-21 | 内因性タンパク質のレベルを低下させることによって生物学的産物の産生を改善する方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862697480P | 2018-07-13 | 2018-07-13 | |
| US62/697,480 | 2018-07-13 | ||
| PCT/US2019/041615 WO2020014618A1 (en) | 2018-07-13 | 2019-07-12 | Methods for improving production of biological products by reducing the level of endogenous protein |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024139532A Division JP2024161560A (ja) | 2018-07-13 | 2024-08-21 | 内因性タンパク質のレベルを低下させることによって生物学的産物の産生を改善する方法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021530225A JP2021530225A (ja) | 2021-11-11 |
| JPWO2020014618A5 JPWO2020014618A5 (https=) | 2022-07-13 |
| JP2021530225A5 true JP2021530225A5 (https=) | 2022-07-13 |
| JP7543246B2 JP7543246B2 (ja) | 2024-09-02 |
Family
ID=67660787
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021500804A Active JP7543246B2 (ja) | 2018-07-13 | 2019-07-12 | 内因性タンパク質のレベルを低下させることによって生物学的産物の産生を改善する方法 |
| JP2024139532A Pending JP2024161560A (ja) | 2018-07-13 | 2024-08-21 | 内因性タンパク質のレベルを低下させることによって生物学的産物の産生を改善する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024139532A Pending JP2024161560A (ja) | 2018-07-13 | 2024-08-21 | 内因性タンパク質のレベルを低下させることによって生物学的産物の産生を改善する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12497624B2 (https=) |
| EP (1) | EP3807399A1 (https=) |
| JP (2) | JP7543246B2 (https=) |
| KR (1) | KR20210030949A (https=) |
| CN (2) | CN120174006A (https=) |
| IL (1) | IL280086B2 (https=) |
| SG (1) | SG11202013191TA (https=) |
| WO (1) | WO2020014618A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI912369B (zh) * | 2020-09-21 | 2026-01-21 | 法商賽諾菲公司 | 用於生產治療蛋白之高生產重組中國倉鼠卵巢細胞株之世代 |
| WO2024178239A1 (en) * | 2023-02-22 | 2024-08-29 | Shattuck Labs, Inc. | Engineered cell lines and uses thereof |
| EP4438622A1 (en) * | 2023-03-30 | 2024-10-02 | Sartorius Stedim Cellca GmbH | Cho cells with optimized ecm profile |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9022545D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
| IT1258959B (it) | 1992-06-09 | 1996-03-11 | Impianto a moduli mobili per lo sviluppo e la produzione di prodotti biotecnologici su scala pilota | |
| EP1958962A3 (en) | 1997-06-12 | 2013-05-01 | Novartis International Pharmaceutical Ltd. | Artificial antibody polypeptides |
| DE10256083A1 (de) | 2002-11-29 | 2004-08-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Expressionsvektor, Verfahren zur Herstellung von heterologen Genprodukten und Selektionsverfahren für hochproduzierende rekombinante Zellen |
| EP1719025B1 (en) | 2004-02-03 | 2019-10-23 | GE Healthcare Bio-Sciences Corp. | System and method for manufacturing |
| MXPA06014099A (es) | 2004-06-04 | 2007-05-09 | Xcellerex Inc | Sistemas biorreactores desechables y metodos. |
| US7531327B2 (en) * | 2004-07-23 | 2009-05-12 | Immunomedics, Inc. | Methods and compositions for increasing longevity and protein yield from a cell culture |
| CA2632520A1 (en) | 2005-12-05 | 2007-06-14 | Ernest G. Hope | Prevalidated, modular good manufacturing practice-compliant facility |
| EP2528002B1 (en) | 2007-04-16 | 2015-11-04 | Momenta Pharmaceuticals, Inc. | Defined glycoprotein products and related methods |
| EP2216395A1 (en) | 2009-02-09 | 2010-08-11 | Lonza Biologics plc. | Bioreactor for the cultivation of mammalian cells |
| US8771635B2 (en) | 2010-04-26 | 2014-07-08 | Toyota Motor Engineering & Manufacturing North America, Inc. | Hydrogen release from complex metal hydrides by solvation in ionic liquids |
| US10371394B2 (en) | 2010-09-20 | 2019-08-06 | Biologics Modular Llc | Mobile, modular cleanroom facility |
| WO2012082509A2 (en) * | 2010-12-15 | 2012-06-21 | Sigma-Aldrich Co. Llc | Biomarkers for enhanced protein production |
| US9388373B2 (en) | 2011-03-08 | 2016-07-12 | University Of Maryland Baltimore County | Microscale bioprocessing system and method for protein manufacturing |
| KR102530118B1 (ko) * | 2012-07-25 | 2023-05-08 | 더 브로드 인스티튜트, 인코퍼레이티드 | 유도 ｄｎａ 결합 단백질 및 게놈 교란 도구 및 이의 적용 |
| SI2970875T2 (sl) | 2013-03-15 | 2026-03-31 | F. Hoffmann-La Roche Ag | Sestavki celičnih kultur z antioksidanti in postopki za proizvodnjo polipeptidov |
| WO2015103438A2 (en) * | 2014-01-02 | 2015-07-09 | Genelux Corporation | Oncolytic virus adjunct therapy with agents that increase virus infectivity |
| EP3556858A3 (en) | 2014-04-09 | 2020-01-22 | Editas Medicine, Inc. | Crispr/cas-related methods and compositions for treating cystic fibrosis |
| WO2017186671A1 (en) * | 2016-04-25 | 2017-11-02 | Danmarks Tekniske Universitet | Engineered mammalian cells for production of recombinant proteins |
| CN107354157B (zh) * | 2017-07-20 | 2020-05-19 | 浙江大学 | 特异性抑制LAMB1基因表达的siRNA及其重组载体和应用 |
-
2019
- 2019-07-12 JP JP2021500804A patent/JP7543246B2/ja active Active
- 2019-07-12 IL IL280086A patent/IL280086B2/en unknown
- 2019-07-12 CN CN202510267020.3A patent/CN120174006A/zh active Pending
- 2019-07-12 WO PCT/US2019/041615 patent/WO2020014618A1/en not_active Ceased
- 2019-07-12 SG SG11202013191TA patent/SG11202013191TA/en unknown
- 2019-07-12 CN CN201980046173.8A patent/CN112424339B/zh active Active
- 2019-07-12 KR KR1020217003402A patent/KR20210030949A/ko active Pending
- 2019-07-12 US US17/259,699 patent/US12497624B2/en active Active
- 2019-07-12 EP EP19755706.9A patent/EP3807399A1/en active Pending
-
2024
- 2024-08-21 JP JP2024139532A patent/JP2024161560A/ja active Pending
-
2025
- 2025-11-04 US US19/378,975 patent/US20260062709A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021530225A5 (https=) | ||
| Nordström | Plasmid R1—replication and its control | |
| JP2018515107A5 (https=) | ||
| JP2017205126A5 (https=) | ||
| JP2017514501A5 (https=) | ||
| JP2019524140A5 (https=) | ||
| RU2013152648A (ru) | Аденовирус обезьян и гибридные аденовирусные векторы | |
| JP2018534937A5 (https=) | ||
| JP2019515666A5 (https=) | ||
| JP2014501505A5 (https=) | ||
| JP2019511921A5 (https=) | ||
| JP2014525247A5 (https=) | ||
| JP7297331B2 (ja) | 環状ｒｎａを使用したタンパク質翻訳およびその応用 | |
| JP2021534818A5 (https=) | ||
| JP2014530609A5 (https=) | ||
| JPWO2020014618A5 (https=) | ||
| JP2019503998A5 (https=) | ||
| JP7382138B2 (ja) | Ｈｓｐａ５遺伝子のプロモーター | |
| JP5073653B2 (ja) | 高レベルのタンパク質を産生する発現ベクター及び方法 | |
| JPWO2020245169A5 (https=) | ||
| CN114539429B (zh) | 融合蛋白组合物及其应用 | |
| CN1938424A (zh) | 在轻度低温下能促进基因表达的序列 | |
| JP2009077737A5 (https=) | ||
| JPWO2021262783A5 (https=) | ||
| WO2006013859A1 (ja) | 酵母プロモーター |