|
US5521184A
(en)
|
1992-04-03 |
1996-05-28 |
Ciba-Geigy Corporation |
Pyrimidine derivatives and processes for the preparation thereof
|
|
ATE459616T1
(de)
|
1998-08-11 |
2010-03-15 |
Novartis Ag |
Isochinoline derivate mit angiogenesis-hemmender wirkung
|
|
US6133031A
(en)
|
1999-08-19 |
2000-10-17 |
Isis Pharmaceuticals Inc. |
Antisense inhibition of focal adhesion kinase expression
|
|
GB9905075D0
(en)
|
1999-03-06 |
1999-04-28 |
Zeneca Ltd |
Chemical compounds
|
|
GB0004890D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
ATE273695T1
(de)
|
2000-06-28 |
2004-09-15 |
Smithkline Beecham Plc |
Nassvermahlung
|
|
IL160915A0
(en)
|
2001-09-19 |
2004-08-31 |
Aventis Pharma Sa |
Indolizines inhibiting kinase proteins
|
|
ES2269793T3
(es)
|
2001-10-30 |
2007-04-01 |
Novartis Ag |
Derivados de estaurospina como inhibidores de la actividad de tirosina quinasa receptora flt3.
|
|
TW200406374A
(en)
|
2002-05-29 |
2004-05-01 |
Novartis Ag |
Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases
|
|
GB0215676D0
(en)
|
2002-07-05 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
|
CL2003002353A1
(es)
|
2002-11-15 |
2005-02-04 |
Vertex Pharma |
Compuestos derivados de diaminotriazoles, inhibidores d ela proteina quinasa; composicion farmaceutica; procedimiento de preparacion; y su uso del compuesto en el tratamiento de enfermedades de desordenes alergicos, proliferacion, autoinmunes, condic
|
|
UA80767C2
(en)
|
2002-12-20 |
2007-10-25 |
Pfizer Prod Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
|
GB0305929D0
(en)
|
2003-03-14 |
2003-04-23 |
Novartis Ag |
Organic compounds
|
|
AR045944A1
(es)
|
2003-09-24 |
2005-11-16 |
Novartis Ag |
Derivados de isoquinolina 1.4-disustituidas
|
|
RU2007123675A
(ru)
|
2004-11-24 |
2008-12-27 |
Новартис АГ (CH) |
Комбинации ингибиторов jak
|
|
PL2931738T3
(pl)
|
2012-12-13 |
2019-07-31 |
Aduro Biotech, Inc. |
Kompozycje zawierające cykliczne dinukleotydy purynowe o zdefiniowanej stereochemii i sposoby ich otrzymywania i zastosowania
|
|
CN109394752A
(zh)
|
2013-10-21 |
2019-03-01 |
德雷克塞尔大学 |
治疗慢性乙型肝炎病毒感染的sting激动剂的用途
|
|
JP2016538344A
(ja)
|
2013-11-19 |
2016-12-08 |
ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ |
癌処置としてのｓｔｉｎｇアゴニストの使用
|
|
KR102409739B1
(ko)
|
2014-03-20 |
2022-06-17 |
카펠라 테라퓨틱스, 인크. |
암 치료용의 ｅｒｂｂ 티로신 키나제 억제제로서의 벤즈이미다졸 유도체
|
|
PE20170198A1
(es)
|
2014-06-04 |
2017-04-08 |
Glaxosmithkline Ip Dev Ltd |
Dinucleotidos ciclicos como moduladores de sting
|
|
WO2016096577A1
(en)
|
2014-12-16 |
2016-06-23 |
Invivogen |
Combined use of a chemotherapeutic agent and a cyclic dinucleotide for cancer treatment
|
|
GB201501462D0
(en)
|
2015-01-29 |
2015-03-18 |
Glaxosmithkline Ip Dev Ltd |
Novel compounds
|
|
WO2017011444A1
(en)
|
2015-07-13 |
2017-01-19 |
The Wistar Institute Of Anatomy And Biology |
Methods and compositions for treating b cell cancers
|
|
TW201717968A
(zh)
|
2015-07-14 |
2017-06-01 |
春季銀行製藥公司 |
誘導ｒｉｇ－ｉ和其他模式辨識受體之化合物及組成物
|
|
US10844051B2
(en)
|
2015-07-22 |
2020-11-24 |
The Royal Institution For The Advancement Of Learning/Mcgill University |
Substituted oxazoles for the treatment of cancer
|
|
CR20180101A
(es)
|
2015-08-13 |
2018-04-12 |
Merck Sharp & Dohme |
Compuestos di-nucleóticos cíclicos como agonistas de sting
|
|
WO2017053537A1
(en)
|
2015-09-23 |
2017-03-30 |
Capella Therapeutics, Inc. |
Benzimidazoles for use in the treatment of cancer and inflammatory diseases
|
|
CN105367617A
(zh)
|
2015-09-25 |
2016-03-02 |
武汉品生科技有限公司 |
一种基于环二腺核苷酸的衍生物、tat多肽及其在一型干扰素小分子中抑制剂的应用
|
|
US20170146519A1
(en)
|
2015-11-20 |
2017-05-25 |
Oregon Health & Science University |
Sting agonists and methods of selecting sting agonists
|
|
TWI704154B
(zh)
|
2015-12-03 |
2020-09-11 |
英商葛蘭素史克智慧財產發展有限公司 |
新穎化合物
|
|
EP3386536A4
(en)
|
2015-12-07 |
2019-07-31 |
Opi Vi- IP Holdco LLC |
COMPOSITION OF ANTIBODY CONSTRUCT AGONIST CONJUGATES AND METHOD FOR USE THEREOF
|
|
US20180369268A1
(en)
|
2015-12-16 |
2018-12-27 |
Aduro Biotech, Inc. |
Methods for identifying inhibitors of "stimulator of interferon gene"- dependent interferon production
|
|
WO2017123657A1
(en)
|
2016-01-11 |
2017-07-20 |
Gary Glick |
Cyclic dinucleotides for treating conditions associated with sting activity such as cancer
|
|
RS67188B1
(sr)
|
2016-01-11 |
2025-10-31 |
Innate Tumor Immunity Inc |
Ciklični dinukleotidi za lečenje stanja povezanih sa aktivnošću sting kao što je kancer
|
|
MX2018010586A
(es)
|
2016-03-02 |
2019-03-28 |
Univ Texas |
Nanovacuna de activacion de "sting" para inmunoterapia.
|
|
SG10201912074PA
(en)
|
2016-03-18 |
2020-02-27 |
Immune Sensor Llc |
Cyclic di-nucleotide compounds and methods of use
|
|
JP2019510802A
(ja)
*
|
2016-04-07 |
2019-04-18 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ |
タンパク質調節物質として有用な複素環アミド
|
|
HRP20220936T1
(hr)
|
2016-04-07 |
2022-10-28 |
Glaxosmithkline Intellectual Property Development Limited |
Heterociklički amidi korisni kao modulatori proteina
|
|
WO2017186711A1
(en)
|
2016-04-25 |
2017-11-02 |
Invivogen |
Novel complexes of immunostimulatory compounds, and uses thereof
|
|
US10537590B2
(en)
|
2016-09-30 |
2020-01-21 |
Boehringer Ingelheim International Gmbh |
Cyclic dinucleotide compounds
|
|
US10414747B2
(en)
|
2016-10-04 |
2019-09-17 |
Merck Sharp & Dohme Corp. |
Benzo[b]thiophene compounds as sting agonists
|
|
WO2018119263A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Heterocyclic compounds derivatives as pd-l1 internalization inducers
|
|
ES2874756T3
(es)
|
2016-12-22 |
2021-11-05 |
Incyte Corp |
Derivados de triazolo[1,5-A]piridina como inmunomoduladores
|
|
AU2017382870B2
(en)
|
2016-12-22 |
2022-03-24 |
Incyte Corporation |
Benzooxazole derivatives as immunomodulators
|
|
ES2899402T3
(es)
|
2016-12-22 |
2022-03-11 |
Incyte Corp |
Derivados de piridina como inmunomoduladores
|
|
EP3558990B1
(en)
|
2016-12-22 |
2022-08-10 |
Incyte Corporation |
Tetrahydro imidazo[4,5-c]pyridine derivatives as pd-l1 internalization inducers
|
|
WO2018119286A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Bicyclic heteroaromatic compounds as immunomodulators
|
|
JP2020524718A
(ja)
|
2017-06-22 |
2020-08-20 |
キュラデブ・ファーマ・リミテッドＣｕｒａｄｅｖ Ｐｈａｒｍａ Ｌｉｍｉｔｅｄ |
ヒトｓｔｉｎｇの複素環式小分子調節因子
|
|
US20200138827A1
(en)
|
2017-06-22 |
2020-05-07 |
Curadev Pharma Limited |
Small molecule modulators of human sting
|
|
PE20200696A1
(es)
|
2017-06-22 |
2020-06-16 |
Curadev Pharma Ltd |
Moduladores de moleculas pequenas de sting humana
|
|
US11312772B2
(en)
|
2017-08-04 |
2022-04-26 |
Merck Sharp & Dohme Corp. |
Combinations of PD-1 antagonists and benzo [b] thiophene STING agonists for cancer treatment
|
|
US11285131B2
(en)
|
2017-08-04 |
2022-03-29 |
Merck Sharp & Dohme Corp. |
Benzo[b]thiophene STING agonists for cancer treatment
|
|
CN107335049B
(zh)
|
2017-08-18 |
2019-10-18 |
中国药科大学 |
菊科类型环肽化合物作为cGAS-STING信号通路抑制剂的应用
|
|
CA3077337A1
(en)
|
2017-10-05 |
2019-04-11 |
Glaxosmithkline Intellectual Property Development Limited |
Modulators of stimulator of interferon genes (sting)
|
|
US20210238172A1
(en)
|
2017-10-05 |
2021-08-05 |
Glaxosmithkline Intellectual Property Development Limited |
Heterocyclic amides useful as protein modulators and methods of using the same
|
|
CN111194214A
(zh)
|
2017-10-05 |
2020-05-22 |
葛兰素史密斯克莱知识产权发展有限公司 |
施用sting激动剂的方法
|
|
CN110016025B
(zh)
|
2018-01-08 |
2021-08-06 |
成都先导药物开发股份有限公司 |
一种免疫调节剂
|
|
DE102018200540A1
(de)
|
2018-01-15 |
2019-07-18 |
Robert Bosch Gmbh |
Verfahren zum Betreiben eines Kraftfahrzeugbordnetzes
|
|
CR20200520A
(es)
|
2018-03-30 |
2021-03-09 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
GB201807924D0
(en)
|
2018-05-16 |
2018-06-27 |
Ctxt Pty Ltd |
Compounds
|
|
ES2929415T3
(es)
|
2018-05-25 |
2022-11-29 |
Incyte Corp |
Compuestos heterocíclicos tricíclicos como activadores de STING
|
|
JP2021530442A
(ja)
|
2018-06-28 |
2021-11-11 |
ジエンス ヘンルイ メデイシンカンパニー リミテッドJiangsu Hengrui Medicine Co., Ltd. |
縮合三環系複素環化合物およびその治療上の使用
|
|
US10875872B2
(en)
|
2018-07-31 |
2020-12-29 |
Incyte Corporation |
Heteroaryl amide compounds as sting activators
|
|
US11008344B2
(en)
|
2018-07-31 |
2021-05-18 |
Incyte Corporation |
Tricyclic heteroaryl compounds as STING activators
|
|
WO2020132549A1
(en)
|
2018-12-21 |
2020-06-25 |
Nimbus Titan, Inc. |
Sting heterocycle agonists and uses thereof
|
|
US12129267B2
(en)
|
2019-01-07 |
2024-10-29 |
Incyte Corporation |
Heteroaryl amide compounds as sting activators
|