JP2020536072A5 - - Google Patents
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- Publication number
- JP2020536072A5 JP2020536072A5 JP2020518459A JP2020518459A JP2020536072A5 JP 2020536072 A5 JP2020536072 A5 JP 2020536072A5 JP 2020518459 A JP2020518459 A JP 2020518459A JP 2020518459 A JP2020518459 A JP 2020518459A JP 2020536072 A5 JP2020536072 A5 JP 2020536072A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- alkyl
- nhc
- heterocycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 0 CCC(CCC(C(N(C)C(C(C)=O)c(cc1)cc(-c(cc(CC(C(NCC(SC)=N)=O)NC(C(C)N)=O)cc2)c2OCCN)c1OCCN)=O)NC(/C1=C\CC/C=C(\c2ccc(C(C)(C)C)cc2)/N=C1\C)=*)C(N)=O Chemical compound CCC(CCC(C(N(C)C(C(C)=O)c(cc1)cc(-c(cc(CC(C(NCC(SC)=N)=O)NC(C(C)N)=O)cc2)c2OCCN)c1OCCN)=O)NC(/C1=C\CC/C=C(\c2ccc(C(C)(C)C)cc2)/N=C1\C)=*)C(N)=O 0.000 description 7
- QLWCCGWUMCFRDU-UHFFFAOYSA-N CC(C(C)=N)NC(C(Cc(cc1-c2cc(C(C(NC3C)=O)N(C)C(C(CCCCN)NC(c(cc4)ccc4-c(cc4)ccc4Cl)=O)=O)ccc2OCCN)ccc1OCCN)NC3=O)=S Chemical compound CC(C(C)=N)NC(C(Cc(cc1-c2cc(C(C(NC3C)=O)N(C)C(C(CCCCN)NC(c(cc4)ccc4-c(cc4)ccc4Cl)=O)=O)ccc2OCCN)ccc1OCCN)NC3=O)=S QLWCCGWUMCFRDU-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762566125P | 2017-09-29 | 2017-09-29 | |
| US62/566,125 | 2017-09-29 | ||
| PCT/US2018/052791 WO2019067498A2 (en) | 2017-09-29 | 2018-09-26 | PEPTIDE ANTIBIOTIC COMPLEXES AND METHODS OF USE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020536072A JP2020536072A (ja) | 2020-12-10 |
| JP2020536072A5 true JP2020536072A5 (https=) | 2021-11-25 |
Family
ID=64744925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020518459A Abandoned JP2020536072A (ja) | 2017-09-29 | 2018-09-26 | ペプチド抗生物質複合体およびその使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20200262869A1 (https=) |
| EP (1) | EP3688028A2 (https=) |
| JP (1) | JP2020536072A (https=) |
| CN (1) | CN111386283A (https=) |
| MA (1) | MA50664A (https=) |
| WO (1) | WO2019067498A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11072635B2 (en) | 2015-11-20 | 2021-07-27 | Rqx Pharmaceuticals, Inc. | Macrocyclic broad spectrum antibiotics |
| ES2961566T3 (es) * | 2019-05-28 | 2024-03-12 | Hoffmann La Roche | Antibióticos macrocíclicos de amplio espectro |
| WO2023245125A2 (en) * | 2022-06-15 | 2023-12-21 | The Board Of Trustees Of The University Of Illinois | In vitro biosynthesis of diverse pyridine-based macrocyclic peptides |
| CN119912684A (zh) * | 2025-01-21 | 2025-05-02 | 中国科学院长春应用化学研究所 | 一种锍盐阳离子吸附剂及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| ATE141502T1 (de) | 1991-01-15 | 1996-09-15 | Alcon Lab Inc | Verwendung von karrageenan in topischen ophthalmologischen zusammensetzungen |
| US5212162A (en) | 1991-03-27 | 1993-05-18 | Alcon Laboratories, Inc. | Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions |
| KR20140140580A (ko) * | 2012-03-14 | 2014-12-09 | 더 스크립스 리서치 인스티튜트 | 광범위 항생제 아릴로마이신 유사체 |
| CN103788176A (zh) * | 2012-10-31 | 2014-05-14 | 上海来益生物药物研究开发中心有限责任公司 | 一种arylomycin类化合物及其制备方法和应用 |
| US11072635B2 (en) * | 2015-11-20 | 2021-07-27 | Rqx Pharmaceuticals, Inc. | Macrocyclic broad spectrum antibiotics |
-
2018
- 2018-09-26 JP JP2020518459A patent/JP2020536072A/ja not_active Abandoned
- 2018-09-26 CN CN201880075907.0A patent/CN111386283A/zh active Pending
- 2018-09-26 EP EP18822169.1A patent/EP3688028A2/en not_active Withdrawn
- 2018-09-26 MA MA050664A patent/MA50664A/fr unknown
- 2018-09-26 WO PCT/US2018/052791 patent/WO2019067498A2/en not_active Ceased
-
2020
- 2020-03-25 US US16/829,963 patent/US20200262869A1/en not_active Abandoned
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