JP2020505190A5

JP2020505190A5 -

Info

Publication number: JP2020505190A5
Application number: JP2019557689A
Authority: JP
Filing date: 2018-01-09
Publication date: 2021-02-18
Anticipated expiration: 2038-01-09

Description

本発明の第一の局面において、光検知手段、流体分配手段、およびアトマイザーから成り、流体分配手段およびアトマイザーは流体連結され、流体分配手段内に収められた流体がアトマイザーを通じて対象表面にスプレーとして分配され、アトマイザーは、窪みとしての、遮光体またはスカートからなり、少なくとも一つの流体出口が遮光体またはスカートの内部空間となる窪みに向かって開口している、活性的歯牙う蝕および／または歯牙侵食の検出装置が提供される。本発明の検出装置は、従来の検出装置に比べて対象表面に施された染出液から放出される光学的シグナルを素早く検出できるという点で有利である。流体分配手段は、染出液を収納しアトマイザーを通じて対象表面に投与することができる。これは、アトマイザーが染出液の均一な分配を施し染出液によって生じた光学的シグナルが検知手段によって検出できるため、有利である。光検知手段は、カメラ、荷電結合素子（ＣＣＤ）または相補型金属酸化物半導体（ＣＭＯＳ）であっても良い。光検知手段は、化学発光性発光タンパク質を含む染出液から発生する弱光シグナルを検出できるように特別に調整されていても良い。
In the first aspect of the present invention, which comprises a light detecting means, a fluid distributing means, and an atomizer, the fluid distributing means and the atomizer are fluid-connected, and the fluid contained in the fluid distributing means is distributed as a spray to the target surface through the atomizer. The atomizer consists of a shading body or skirt, as a depression, with at least one fluid outlet opening towards the depression that becomes the internal space of the shading body or skirt, active tooth caries and / or tooth erosion. Detection device is provided. The detection device of the present invention is advantageous in that it can quickly detect the optical signal emitted from the exudate applied to the target surface as compared with the conventional detection device. The fluid dispensing means can store the exudate and administer it to the surface of the subject through an atomizer. This is advantageous because the atomizer uniformly distributes the exudate and the optical signal generated by the exudate can be detected by the detection means. The photodetector may be a camera, a charge-coupled device (CCD) or a complementary metal oxide semiconductor (CMOS). The photodetector may be specially tuned to detect a weak light signal generated from the exudate containing the chemiluminescent photoprotein.

好ましくは、着脱自在なアプリケーター部は、アプリケーターハウジング部、着脱自在に組み合わせたアトマイザーおよび流体通路連合部からなり、遮光体またはスカートは着脱自在である。この配置は、少なくとも一部の構成要素を使い捨てとすることができるため有利である。例えば、着脱自在に組み合わせたアトマイザーおよび流体通路連合部および着脱自在な遮光体またはスカート部は使い捨てとし、アプリケーターハウジング部はオートクレーブ可能とすることができる。着脱自在に組み合わせたアトマイザーおよび流体通路連合部および着脱自在な遮光体またはスカート部は交差汚染を防ぐため有利である。また、着脱自在に組み合わせたアトマイザーおよび流体通路連合部の再使用は、流体通路の目詰まりや閉塞につながり、装置の最適な運転を妨げる恐れがある。加えて、着脱自在な遮光体またはスカート部として、異なる対象表面用に異なる大きさの遮光体／スカートを使用できる。例えば、異なる大きさの遮光体またはスカートを異なる大きさの歯に使用することができる。歯が異なる大きさや形状であるため、より大きな、または小さな遮光体またはスカートを使う必要があることもある。また、装置を歯の表面に乗せるために遮光体またはスカートの両側に切り込みまたは間隙が必要となることもある。
Preferably, the removable applicator portion comprises an applicator housing portion, a detachably combined atomizer and a fluid passage association portion , and the shading body or skirt is removable . This arrangement is advantageous because at least some of the components can be disposable. For example, the detachably combined atomizer and fluid passage association portion and the detachable shading body or skirt portion can be disposable, and the applicator housing portion can be autoclaved. Detachable combination atomizer and fluid passage associations and removable shading or skirt are advantageous to prevent cross-contamination. In addition, the reuse of the detachable atomizer and the fluid passage association portion may lead to clogging or blockage of the fluid passage, and may hinder the optimum operation of the device. In addition, different sized shading bodies / skirts can be used for different target surfaces as removable shading bodies or skirts. For example, different sized shading bodies or skirts can be used for different sized teeth. Due to the different sizes and shapes of the teeth, it may be necessary to use larger or smaller shading bodies or skirts. It may also require cuts or gaps on either side of the shading body or skirt to allow the device to rest on the tooth surface.

Claims

It consists of a photodetector, a fluid distributor, and an atomizer. The fluid distributor and atomizer are fluid-connected, and the fluid contained in the fluid distributor is distributed to the target surface through the atomizer .
The atomizer consists of a light shield or skirt as a recess, with at least one fluid outlet opening towards the recess that is the interior space of the light shield or skirt.
A detector for active dental caries and / or tooth erosion.

The detection device according to claim 1, further comprising a main body portion and an applicator portion including a proximal end and a distal end.

The detection device according to claim 1, wherein the applicator portion is removable and is connected to the distal end of the main body portion.

The detection device according to claim 3, wherein the removable applicator portion comprises an atomizer.

The detection device according to claim 1, wherein the atomizer has at least one fluid atomizer path that fluidly connects with at least one fluid outlet.

Atomizer Chi lifting a plurality of fluid atomizer path connecting a plurality of fluid outlet and the fluid is adjusted by a plurality of fluid outlets therein so as to provide substantially the same fluid flow, essentially from a plurality of fluid outlets The detection device according to claim 1, wherein a fluid of the same flow is provided by a first fluid outlet set and a second fluid outlet set in which the fluid is fluidly connected through a fluid atomizer path .

The detection device according to any one of claims 2 to 6 , wherein the detachable applicator portion includes an applicator housing portion, a detachably combined atomizer, and a fluid passage association portion, and a light-shielding body or a skirt is removable .

The detection device according to claim 7 , wherein the applicator housing portion and the detachably combined atomizer and fluid passage association portion are reversibly connected in a sliding manner.

The detection device according to claim 7 or 8 , wherein the detachably combined atomizer and fluid passage association portion, and the detachable shading body or skirt portion are reversibly connected.

The detachable combination of atomizer and fluid passage association consists of a male connector adjusted to match the female connector of the applicator housing, and the male and female connectors provide a fluid path for fluid connection with the fluid distribution means. The detection device according to any one of claims 7 to 8 , which is formed.

The detection device according to any one of claims 5 to 10 , wherein the atomizer comprises at least four fluid outlets and at least two fluid atomizer paths.

Diameter of the plurality of fluid atomizer path, detecting device according to any one of claims 1 to 11 is between about 1 mm ² to about 3 mm ² in sectional area.

The detection device according to claim 10 , wherein the diameter of the plurality of fluid atomizer paths is about 2 mm ² in cross-sectional area.

The detection device according to claim 1, wherein the photodetector is tuned to detect luminescence generated by a bioluminescent protein.

The detection device according to claim 1, wherein the light detection means is a camera sensor.

The detection device according to claim 1, wherein the detection device further includes a light source.

The detection device according to claim 1 , wherein the fluid distribution means further comprises a syringe and a syringe drive means, and the syringe drive means is adjusted to operate a syringe pusher to push out the liquid contained therein. ..

A kit comprising the detection device according to claim 1.

The kit of claim 18 , wherein the detector comprises a body, at least one applicator, and at least one syringe.