JP2019529371A5 - - Google Patents
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- JP2019529371A5 JP2019529371A5 JP2019511517A JP2019511517A JP2019529371A5 JP 2019529371 A5 JP2019529371 A5 JP 2019529371A5 JP 2019511517 A JP2019511517 A JP 2019511517A JP 2019511517 A JP2019511517 A JP 2019511517A JP 2019529371 A5 JP2019529371 A5 JP 2019529371A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- seq
- antibody
- antigen
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662380562P | 2016-08-29 | 2016-08-29 | |
| US62/380,562 | 2016-08-29 | ||
| PCT/US2017/048137 WO2018044640A1 (en) | 2016-08-29 | 2017-08-23 | Anti-gremlin-1 (grem1) antibodies and methods of use thereof for treating pulmonary arterial hypertension |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019529371A JP2019529371A (ja) | 2019-10-17 |
| JP2019529371A5 true JP2019529371A5 (https=) | 2020-10-01 |
Family
ID=59791160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511517A Pending JP2019529371A (ja) | 2016-08-29 | 2017-08-23 | 肺動脈性肺高血圧を処置するための抗グレムリン−1(grem1)抗体およびその使用の方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20180057580A1 (https=) |
| EP (1) | EP3504238A1 (https=) |
| JP (1) | JP2019529371A (https=) |
| KR (1) | KR20190040320A (https=) |
| CN (1) | CN109641954A (https=) |
| AU (1) | AU2017320989A1 (https=) |
| CA (1) | CA3031783A1 (https=) |
| EA (1) | EA201990613A1 (https=) |
| IL (1) | IL264309A (https=) |
| MA (1) | MA46046A (https=) |
| MX (1) | MX2019002382A (https=) |
| WO (1) | WO2018044640A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3574017A1 (en) | 2017-01-27 | 2019-12-04 | Kymab Limited | Anti-opg antibodies |
| WO2021257947A1 (en) | 2020-06-18 | 2021-12-23 | Regeneron Pharmaceuticals, Inc. | Activin a antibody formulations and methods of use thereof |
| JP2024504124A (ja) * | 2021-01-18 | 2024-01-30 | スーチョウ・トランスセンタ・セラピューティクス・カンパニー・リミテッド | 新規の抗グレムリン1抗体 |
| EP4511395A1 (en) * | 2022-04-20 | 2025-02-26 | Kantonsspital St. Gallen | Antibodies or antigen-binding fragments pan-specifically binding to gremlin-1 and gremlin-2 and uses thereof |
| PE20260306A1 (es) | 2023-06-12 | 2026-02-11 | Amgen Inc | Proteinas de union a receptor de linfotoxina beta agonistas |
| CN117801109B (zh) * | 2024-03-01 | 2024-05-03 | 再少年(北京)生物科技有限公司 | iPS诱导定向分化成内皮祖细胞的方法及应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2437213A1 (fr) | 1978-09-28 | 1980-04-25 | Cm Ind | Produits cytotoxiques formes par liaison covalente de la chaine a de la ricine avec un anticorps et leur procede de preparation |
| US6573096B1 (en) | 2000-04-01 | 2003-06-03 | The Research Foundation At State University Of New York | Compositions and methods for inhibition of cancer invasion and angiogenesis |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| US20040101920A1 (en) | 2002-11-01 | 2004-05-27 | Czeslaw Radziejewski | Modification assisted profiling (MAP) methodology |
| WO2005103081A2 (en) | 2004-04-20 | 2005-11-03 | Genmab A/S | Human monoclonal antibodies against cd20 |
| US7411046B2 (en) | 2005-08-02 | 2008-08-12 | Arius Research Inc | Cancerous disease modifying antibodies |
| US7420040B2 (en) | 2006-02-24 | 2008-09-02 | Arius Research Inc. | Cytotoxicity mediation of cells evidencing surface expression of TROP-2 |
| AU2012350654C1 (en) * | 2011-12-12 | 2018-05-10 | Pieris Ag | Methods for preventing or treating disorders by increasing bioavailability of iron and related pharmaceutical formulation |
| ES2733998T3 (es) * | 2012-10-29 | 2019-12-03 | Cardio Incorporated | Agente terapéutico específico de enfermedad pulmonar |
| ES2898620T3 (es) * | 2013-03-14 | 2022-03-08 | Regeneron Pharma | Anticuerpos humanos contra GREM 1 |
-
2017
- 2017-08-23 CN CN201780052609.5A patent/CN109641954A/zh active Pending
- 2017-08-23 AU AU2017320989A patent/AU2017320989A1/en not_active Abandoned
- 2017-08-23 US US15/684,073 patent/US20180057580A1/en not_active Abandoned
- 2017-08-23 EP EP17761986.3A patent/EP3504238A1/en not_active Withdrawn
- 2017-08-23 MX MX2019002382A patent/MX2019002382A/es unknown
- 2017-08-23 CA CA3031783A patent/CA3031783A1/en not_active Abandoned
- 2017-08-23 KR KR1020197008656A patent/KR20190040320A/ko not_active Ceased
- 2017-08-23 MA MA046046A patent/MA46046A/fr unknown
- 2017-08-23 JP JP2019511517A patent/JP2019529371A/ja active Pending
- 2017-08-23 WO PCT/US2017/048137 patent/WO2018044640A1/en not_active Ceased
- 2017-08-23 EA EA201990613A patent/EA201990613A1/ru unknown
-
2019
- 2019-01-17 IL IL264309A patent/IL264309A/en unknown
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