JP2019519210A5 - - Google Patents
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- JP2019519210A5 JP2019519210A5 JP2018559834A JP2018559834A JP2019519210A5 JP 2019519210 A5 JP2019519210 A5 JP 2019519210A5 JP 2018559834 A JP2018559834 A JP 2018559834A JP 2018559834 A JP2018559834 A JP 2018559834A JP 2019519210 A5 JP2019519210 A5 JP 2019519210A5
- Authority
- JP
- Japan
- Prior art keywords
- delta
- cells
- epitope
- selectively
- tcr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022133983A JP7791789B2 (ja) | 2016-05-12 | 2022-08-25 | γδＴ細胞集団の選択的増殖方法及びその組成物 |
| JP2025123803A JP2025170245A (ja) | 2016-05-12 | 2025-07-24 | γδＴ細胞集団の選択的増殖方法及びその組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662335572P | 2016-05-12 | 2016-05-12 | |
| US62/335,572 | 2016-05-12 | ||
| PCT/US2017/032530 WO2017197347A1 (en) | 2016-05-12 | 2017-05-12 | METHODS FOR SELECTIVE EXPANSION OF γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022133983A Division JP7791789B2 (ja) | 2016-05-12 | 2022-08-25 | γδＴ細胞集団の選択的増殖方法及びその組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019519210A JP2019519210A (ja) | 2019-07-11 |
| JP2019519210A5 true JP2019519210A5 (https=) | 2020-06-25 |
| JP7210286B2 JP7210286B2 (ja) | 2023-01-23 |
Family
ID=60267413
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559834A Active JP7210286B2 (ja) | 2016-05-12 | 2017-05-12 | γδＴ細胞集団の選択的増殖方法及びその組成物 |
| JP2022133983A Active JP7791789B2 (ja) | 2016-05-12 | 2022-08-25 | γδＴ細胞集団の選択的増殖方法及びその組成物 |
| JP2025123803A Pending JP2025170245A (ja) | 2016-05-12 | 2025-07-24 | γδＴ細胞集団の選択的増殖方法及びその組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022133983A Active JP7791789B2 (ja) | 2016-05-12 | 2022-08-25 | γδＴ細胞集団の選択的増殖方法及びその組成物 |
| JP2025123803A Pending JP2025170245A (ja) | 2016-05-12 | 2025-07-24 | γδＴ細胞集団の選択的増殖方法及びその組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11299708B2 (https=) |
| EP (1) | EP3454870A4 (https=) |
| JP (3) | JP7210286B2 (https=) |
| KR (1) | KR102519861B1 (https=) |
| CN (2) | CN118421557A (https=) |
| AU (2) | AU2017261804A1 (https=) |
| CA (1) | CA3023993A1 (https=) |
| IL (2) | IL301527B2 (https=) |
| MX (2) | MX2018013864A (https=) |
| WO (1) | WO2017197347A1 (https=) |
| ZA (1) | ZA201808140B (https=) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2019525898A (ja) | 2016-06-10 | 2019-09-12 | ガデタ・ベー・フェー | ヒト白血球抗原拘束ガンマデルタｔ細胞受容体及びその使用方法 |
| NZ750256A (en) | 2016-08-03 | 2026-02-27 | Dipersio John F | Gene editing of car-t cells for the treatment of t cell malignancies with chimeric antigen receptors |
| EP3580331B1 (en) * | 2017-02-08 | 2022-06-01 | Agency For Science, Technology And Research | Gamma delta t cells and a method of augmenting the tumoricidal activity of the same |
| JP7486953B2 (ja) * | 2017-05-18 | 2024-05-20 | ユーエムセー・ユトレヒト・ホールディング・ベー・フェー | 細胞標的化療法のための組成物および方法 |
| US20200308279A1 (en) | 2017-10-06 | 2020-10-01 | Oslo Universitetssykehus Hf | Chimeric antigen receptors |
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| US10519236B2 (en) | 2018-01-23 | 2019-12-31 | New York University | Antibodies specific to delta 1 chain of T cell receptor |
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| CN112512538A (zh) * | 2018-05-18 | 2021-03-16 | 国家儿童医疗中心 | 改进的靶向t细胞疗法 |
| US20210283180A1 (en) * | 2018-07-06 | 2021-09-16 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Car t cell therapy to target t cell specific cancers |
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| CN113272016A (zh) * | 2018-10-01 | 2021-08-17 | 阿迪塞特生物股份有限公司 | 关于治疗实体肿瘤的工程化和非工程化γδ-T细胞的组合物和方法 |
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| TW202039831A (zh) * | 2018-11-05 | 2020-11-01 | 美商艾歐凡斯生物治療公司 | 對抗ｐｄ－１抗體呈現難治性之非小細胞肺癌（ｎｓｃｌｃ）病患之治療 |
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| US12084500B2 (en) | 2019-01-23 | 2024-09-10 | New York University | Antibodies specific to delta 1 chain of T cell receptor |
| CA3132028A1 (en) * | 2019-03-30 | 2020-10-08 | Biontech Us Inc. | Compositions and methods for preparing t cell compositions and uses thereof |
| US20220290101A1 (en) * | 2019-08-16 | 2022-09-15 | GammaDelta Therapeutics Limited | Ex vivo gamma delta t cell populations |
| CA3145523A1 (en) | 2019-08-16 | 2021-02-25 | GammaDelta Therapeutics Limited | Therapeutic uses of anti-tcr delta variable 1 antibodies |
| US20210130461A1 (en) | 2019-10-31 | 2021-05-06 | Morphosys Ag | Anti-tumor combination therapy comprising anti-cd19 antibody and gamma delta t-cells |
| JP2023504185A (ja) * | 2019-12-03 | 2023-02-01 | アディセット バイオ， インコーポレイテッド | γδＴ細胞集団を多価薬剤で増殖させるための方法及びその組成物 |
| WO2021142260A1 (en) * | 2020-01-10 | 2021-07-15 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for modulation of acvr1 |
| GB202002581D0 (en) * | 2020-02-24 | 2020-04-08 | Gammadelta Therapeutics Ltd | Novel antibodies |
| IL296358A (en) * | 2020-03-13 | 2022-11-01 | Janssen Biotech Inc | Materials and methods for modulating delta chain mediated immunity |
| EP4146702A4 (en) * | 2020-05-07 | 2024-07-10 | Phanes Therapeutics, Inc. | Anti-tumor associated antigen antibodies and uses thereof |
| GB202006989D0 (en) * | 2020-05-12 | 2020-06-24 | Gammadelta Therapeutics Ltd | Methods for isolating gamma delta t cells |
| CN111748519A (zh) * | 2020-07-06 | 2020-10-09 | 深圳市人民医院 | 成纤维细胞的原代培养方法 |
| AU2021324767A1 (en) * | 2020-08-12 | 2023-04-13 | University Of Central Florida Research Foundation, Inc. | Methods and compositions for stimulating gamma delta T cells |
| LT4269444T (lt) | 2020-08-14 | 2024-09-25 | GammaDelta Therapeutics Limited | Daugiaspecifiniai anti-tcr kintamos delta 1 antikūnai |
| GB202013962D0 (en) | 2020-09-04 | 2020-10-21 | Gammadelta Therapeutics Ltd | Immunotherapy composition |
| TW202246338A (zh) * | 2021-02-17 | 2022-12-01 | 英商適應生物治療有限公司 | 抗ＴＣＲδ可變1抗體 |
| AU2022222299A1 (en) | 2021-02-17 | 2023-09-07 | F-Star Therapeutics Limited | Multispecific anti-tcr delta variable 1 antibodies |
| WO2022258606A1 (en) * | 2021-06-07 | 2022-12-15 | Gadeta B.V. | Delta T-cell or Gamma T-cell receptor chains or parts thereof that mediate an anti-tumour or anti-infective response |
| JP2024539088A (ja) * | 2021-10-20 | 2024-10-28 | ユニバーシティ オブ ピッツバーグ －オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | 腫瘍浸潤ガンマ－デルタｔ細胞を拡大するための方法及び材料 |
| US11999968B2 (en) * | 2021-10-22 | 2024-06-04 | Fullhope Biomedical Co., Ltd | Modified T cells, pharmaceutical composition, manufacturing method thereof, and method of using the same |
| CA3238458A1 (en) * | 2021-11-18 | 2023-05-25 | Regents Of The University Of Minnesota | Large-scale expansion of engineered human gamma delta t cells |
| JP2024546123A (ja) * | 2021-12-09 | 2024-12-17 | ザ ユニバーシティー オブ メルボルン | 改変されたｔ細胞受容体及びその使用 |
| MX2024010047A (es) | 2022-02-16 | 2024-08-26 | Priothera Sas | Metodos de tratamiento con celulas car en combinacion con moduladores del receptor s1p. |
| CA3208653A1 (en) | 2022-02-17 | 2022-08-25 | Mihriban Tuna | Multispecific anti-tcr delta variable 1 antibodies |
| EP4543466A1 (en) * | 2022-06-21 | 2025-04-30 | Kiromic BioPharma, Inc. | Methods for generating gamma delta t-cells and related compositions |
| JP2025519645A (ja) * | 2022-06-23 | 2025-06-26 | ラヴァ・セラピューティクス・エヌ・ヴイ | Ｔ細胞依存性多重特異性化合物のアッセイ |
| JP2025541604A (ja) * | 2022-11-02 | 2025-12-22 | ティゲン・ファーマ・ソシエテ・アノニム | リンパ球の拡大 |
| CN120359293A (zh) * | 2022-12-15 | 2025-07-22 | 加利福尼亚大学董事会 | 用于免疫疗法的增强型gamma delta t细胞 |
| WO2024238812A2 (en) * | 2023-05-16 | 2024-11-21 | The Brigham And Women’S Hospital, Inc. | Metabolically enhanced vd1 t cells and uses thereof |
| IL326116A (en) * | 2023-07-26 | 2026-03-01 | Janssen Biotech Inc | Materials and methods for cell culture |
| CN121752599A (zh) * | 2023-08-31 | 2026-03-27 | 南京传奇生物科技有限公司 | 抗γδTCR抗体及其用途 |
| TW202537974A (zh) * | 2023-11-15 | 2025-10-01 | 大陸商上海盛迪醫藥有限公司 | Ｔｒｇｖ９結合蛋白及其醫藥用途 |
| WO2026013158A1 (en) | 2024-07-10 | 2026-01-15 | Cytospire Therapeutics Limited | Antibodies binding to constant domains of gamma delta t-cell receptors |
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| US5185250A (en) | 1986-07-03 | 1993-02-09 | T Cell Sciences, Inc. | Human γ, δT cell antigen receptor polypeptides and nucleic acids |
| US5260223A (en) | 1986-07-03 | 1993-11-09 | President & Fellows Of Harvard College | Methods for detection of human gamma, γ T cell receptor |
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| CA2110946A1 (en) | 1992-12-09 | 1994-06-10 | Elazar Rabbani | Induction of immunocompatibility by nucleic acid |
| AU783250B2 (en) | 1999-06-17 | 2005-10-06 | Dartmouth College | Autologous adoptive immunotherapy with primed antigen-specific T cells or B cells |
| US6737398B1 (en) | 1999-09-30 | 2004-05-18 | National Jewish Medical And Research Center | Modulation of γδ T cells to regulate airway hyperresponsiveness |
| WO2001022816A1 (en) | 1999-09-30 | 2001-04-05 | National Jewish Medical And Research Center | MODULATION OF ηδ T CELLS TO REGULATE AIRWAY HYPERRESPONSIVENESS |
| EP1476547B1 (en) | 2002-01-23 | 2006-12-06 | The University of Utah Research Foundation | Targeted chromosomal mutagenesis using zinc finger nucleases |
| CN1306027C (zh) | 2002-12-12 | 2007-03-21 | 中国医学科学院基础医学研究所 | 一种体外扩增γδT淋巴细胞的方法 |
| US20060205089A1 (en) | 2003-04-14 | 2006-09-14 | Montana State University | Mapping discontinuous antibody or aptamer epitopes for protein structure determination and other applications |
| US7985739B2 (en) | 2003-06-04 | 2011-07-26 | The Board Of Trustees Of The Leland Stanford Junior University | Enhanced sleeping beauty transposon system and methods for using the same |
| JP5139800B2 (ja) | 2004-06-03 | 2013-02-06 | ノビミューン エスアー | 抗ｃｄ３抗体およびその使用方法 |
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| US20080026986A1 (en) | 2006-06-05 | 2008-01-31 | Rong-Fu Wang | Reversal of the suppressive function of specific t cells via toll-like receptor 8 signaling |
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| AU2009288354A1 (en) | 2008-08-26 | 2010-03-11 | Macrogenics Inc. | T-cell receptor antibodies and methods of use thereof |
| KR101866578B1 (ko) | 2010-01-22 | 2018-06-11 | 다우 아그로사이언시즈 엘엘씨 | 표적화된 게놈 교체 |
| BR112012018115B1 (pt) | 2010-01-23 | 2021-06-22 | Genefluidics, Inc. | Sistema configurado para transportar um líquido armazenado em um ou mais reservatórios dentro de uma ou mais câmaras funcionais, e, método de operação do sistema |
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| WO2013074916A1 (en) | 2011-11-18 | 2013-05-23 | Board Of Regents, The University Of Texas System | Car+ t cells genetically modified to eliminate expression of t- cell receptor and/or hla |
| HRP20201595T1 (hr) | 2011-11-28 | 2020-12-11 | Merck Patent Gmbh | Anti-pd-l1 protutijela i njihova uporaba |
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| US20150259645A1 (en) | 2012-11-08 | 2015-09-17 | INSERM (Institut National de la Santé et de la Recherche Médicale | Method for inducing il-2-free proliferation of gamma delta t cells |
| CN102994448A (zh) | 2012-12-13 | 2013-03-27 | 上海柯莱逊生物技术有限公司 | 一种体外扩增γδT细胞的方法 |
| WO2014134412A1 (en) | 2013-03-01 | 2014-09-04 | Regents Of The University Of Minnesota | Talen-based gene correction |
| JP2016539929A (ja) * | 2013-10-25 | 2016-12-22 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 免疫療法のためのポリクローナルγδＴ細胞 |
| EP3129404B1 (en) | 2014-04-10 | 2026-01-28 | LAVA Therapeutics N.V. | Immunoglobulins binding human vgamma9vdelta2 t cell receptors |
| WO2016081518A2 (en) | 2014-11-17 | 2016-05-26 | Adicet Bio, Inc. | Engineered gamma delta t-cells |
| AU2016274633B2 (en) | 2015-06-09 | 2022-04-21 | Gammadelta Therapeutics Ltd | Methods for the production of TCR gamma delta+ T cells |
| EP3322801A1 (en) | 2015-07-15 | 2018-05-23 | Juno Therapeutics, Inc. | Engineered cells for adoptive cell therapy |
| EP3454870A4 (en) | 2016-05-12 | 2020-03-04 | Adicet Bio Inc. | METHOD FOR SELECTIVE EXPANSION OF GAMMA DELTA T CELL POPULATIONS AND COMPOSITIONS THEREOF |
-
2017
- 2017-05-12 EP EP17796994.6A patent/EP3454870A4/en active Pending
- 2017-05-12 AU AU2017261804A patent/AU2017261804A1/en not_active Abandoned
- 2017-05-12 JP JP2018559834A patent/JP7210286B2/ja active Active
- 2017-05-12 CN CN202410184013.2A patent/CN118421557A/zh active Pending
- 2017-05-12 KR KR1020187035576A patent/KR102519861B1/ko active Active
- 2017-05-12 MX MX2018013864A patent/MX2018013864A/es unknown
- 2017-05-12 CA CA3023993A patent/CA3023993A1/en active Pending
- 2017-05-12 CN CN201780042797.3A patent/CN110072533B/zh active Active
- 2017-05-12 US US15/563,830 patent/US11299708B2/en active Active
- 2017-05-12 IL IL301527A patent/IL301527B2/en unknown
- 2017-05-12 WO PCT/US2017/032530 patent/WO2017197347A1/en not_active Ceased
-
2018
- 2018-11-11 IL IL262919A patent/IL262919B2/en unknown
- 2018-11-12 MX MX2023006546A patent/MX2023006546A/es unknown
- 2018-11-30 ZA ZA2018/08140A patent/ZA201808140B/en unknown
-
2022
- 2022-04-11 US US17/718,152 patent/US12364714B2/en active Active
- 2022-08-25 JP JP2022133983A patent/JP7791789B2/ja active Active
-
2023
- 2023-12-06 AU AU2023278051A patent/AU2023278051A1/en active Pending
-
2025
- 2025-07-24 JP JP2025123803A patent/JP2025170245A/ja active Pending
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