JP2017074293A - Implant - Google Patents

Implant Download PDF

Info

Publication number
JP2017074293A
JP2017074293A JP2015204408A JP2015204408A JP2017074293A JP 2017074293 A JP2017074293 A JP 2017074293A JP 2015204408 A JP2015204408 A JP 2015204408A JP 2015204408 A JP2015204408 A JP 2015204408A JP 2017074293 A JP2017074293 A JP 2017074293A
Authority
JP
Japan
Prior art keywords
implant
positioning
bone defect
positioning hole
hole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015204408A
Other languages
Japanese (ja)
Inventor
平出 恒男
Tsuneo Hiraide
恒男 平出
浩文 松澤
Hirofumi Matsuzawa
浩文 松澤
武彦 中島
Takehiko Nakajima
武彦 中島
Original Assignee
HOYA Technosurgical株式会社
HOYA Technosurgical株式会社
Hoya Technosurgical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HOYA Technosurgical株式会社, HOYA Technosurgical株式会社, Hoya Technosurgical Inc filed Critical HOYA Technosurgical株式会社
Priority to JP2015204408A priority Critical patent/JP2017074293A/en
Publication of JP2017074293A publication Critical patent/JP2017074293A/en
Application status is Pending legal-status Critical

Links

Images

Abstract

An object of the present invention is to provide an implant capable of accurately and quickly installing an implant in a bone defect. An implant 1 has a plate shape covering a bone defect portion 101 formed by losing a skull 10. The implant 1 includes a positioning unit 2 that positions the bone defect 101 with the bone defect 101 covered. The positioning portion 2 has at least one positioning hole 21 formed so as to penetrate the implant 1 in the thickness direction, and when performing positioning, the contour OL2 of the bone defect portion 101 is inserted through the positioning hole 21. The position of is visually recognized. [Selection] Figure 3

Description

  The present invention relates to an implant.

  For example, when a skull is partially lost due to a traffic accident or the like, a skull plate that is an implant is embedded and fixed in the bone defect (bone defect reconstruction). The skull plate is generally made of a plate member having a constant thickness. Moreover, as a constituent material of the skull plate, there are a case where a ceramic material is used and a case where a metal material is used.

  A skull plate made of a ceramic material requires a thickness that can withstand a load from the outside (front side). For this reason, when the bone defect portion is installed so as to be covered with the skull plate, it interferes with the margin of the osteotomy portion of the skull bone defect portion, and a bulge of the thickness of the skull plate is recognized, which can be said to be an unfavorable appearance.

  On the other hand, the skull plate made of a metal material can be made thinner than the skull plate made of a ceramic material, and is set to be slightly larger than the size of the bone defect portion so as to cover the skull. Installed. However, the surface of the skull plate that comes into contact with the skull surface is designed to have a shape corresponding to the undulations of the skull, and depending on the size and shape of the bone defect, the position of the skull plate is likely to be displaced. It was difficult to accurately set up to include the defect. If it could not be installed correctly, there was a risk of forming a space between the skull and the skull plate. In addition, the time for adjusting the position of the skull plate is consumed due to the accurate installation of the skull plate, and as a result, a rapid bone defect reconstruction operation may be hindered.

Japanese Patent No. 4060063

  The objective of this invention is providing the implant which can perform the installation of the implant to a bone defect part correctly and rapidly.

Such an object is achieved by the present inventions (1) to (10) below.
(1) An implant having a plate shape covering a bone defect formed by deleting a bone body,
A positioning part for positioning with the bone defect part in a state of covering the bone defect part,
The positioning portion has at least one positioning hole formed so as to penetrate the implant in the thickness direction, and when performing the positioning, the contour of the bone defect portion is defined through the positioning hole. An implant characterized by being used by visually recognizing a position.
Thereby, the installation of the implant in the bone defect portion can be performed accurately and quickly.

  (2) The implant according to (1), wherein a plurality of the positioning holes are arranged at intervals along the contour.

  Thereby, the installation of the implant in the bone defect part can be performed more accurately and quickly.

  (3) The implant according to (2), wherein two positioning holes among the plurality of positioning holes are arranged symmetrically with respect to a center of the implant in plan view.

  Thereby, the two positioning holes can be arranged as far apart as possible, which is a preferable positioning mode.

  (4) The implant according to (2) or (3), wherein the plurality of positioning holes are unevenly distributed in one direction with respect to a center of the implant in plan view.

  Thereby, in the positioning state in which the implant is positioned, the width of the portion overlapping the bone body of the implant can be made different between the side where the plurality of positioning holes are unevenly distributed and the opposite side.

  (5) The width of the portion of the implant that overlaps the bone body in the positioning state in which the positioning is performed is different on the side where the plurality of positioning holes are unevenly distributed and the opposite side thereof (4) The described implant.

  Thereby, the fixing | fixed part fixed with respect to a bone body can be provided in the state where the width | variety is wide, for example, the implant has covered the bone defect part.

  (6) The implant according to any one of (1) to (5), wherein the positioning hole is circular in a plan view of the implant.

  Thereby, when forming the positioning hole, it can be formed using, for example, a drill, and machining is facilitated.

  (7) The implant according to any one of (1) to (5), wherein the positioning hole has an elongated shape along a part of the outline in a plan view of the implant.

  Thereby, the length of a part of the visible contour per positioning hole can be ensured as long as possible, and thus the implant can be accurately positioned with certainty.

(8) A fixing portion that is fixed to the bone body in a state of covering the bone defect portion,
(1) to (7), wherein the fixing portion has at least one fixing hole formed through the implant in the thickness direction at a position different from the positioning hole and through which a bolt is inserted. The implant according to any one of the above.

  Thereby, the implant in the positioning state can be fixed to the skull via the bolt inserted through the fixing hole.

  (9) The implant according to (8), wherein the positioning hole and the fixing hole have the same shape and size and are each provided with a marker so as to be identifiable.

  As a result, it is possible to reliably prevent the misuse of using the positioning hole as the fixing hole and, conversely, using the fixing hole as the positioning hole. Can be done.

  (10) The implant according to any one of (1) to (9), which is made of a ceramic material or a metal material.

  When the implant is made of a ceramic material, the implant has excellent biocompatibility. When the implant is made of a metal material, the thickness of the implant is thinner than when the implant is made of a ceramic material.

  According to the present invention, for example, when positioning an implant in bone defect reconstruction, the position of the contour of the bone defect can be visually confirmed through the positioning hole. Thereby, the exact position of the outline of a bone defect part can be grasped | ascertained, Therefore Installation of the implant to a bone defect part can be made correctly and rapidly to the state suitable for bone defect part reconstruction.

FIG. 1 is a perspective view showing an example of a usage state of an implant (first embodiment) of the present invention. FIG. 2 is an enlarged cross-sectional view of the implant shown in FIG. 1 and its surroundings. FIG. 3 is a diagram (plan view) viewed from the direction of arrow A in FIG. FIG. 4 is a plan view showing a second embodiment of the implant of the present invention. FIG. 5 is a plan view showing a third embodiment of the implant of the present invention.

  Hereinafter, an implant of the present invention will be described in detail based on a preferred embodiment shown in the accompanying drawings.

<First Embodiment>
FIG. 1 is a perspective view showing an example of a usage state of an implant (first embodiment) of the present invention. FIG. 2 is an enlarged cross-sectional view of the implant shown in FIG. 1 and its surroundings. FIG. 3 is a diagram (plan view) viewed from the direction of arrow A in FIG. In the following, for convenience of explanation, the upper side in FIGS. 1 to 3 (the same applies to FIGS. 4 and 5) is referred to as “upper” or “upper”, and the lower side is referred to as “lower” or “lower”.

  As shown in FIG. 1, when the skull 10 needs to be lost by an operation such as a malignant brain tumor, the bone defect portion 101 formed by the loss is treated using the implant 1. In addition, for example, when a skull is partially lost due to a traffic accident or the like, a treatment for filling the bone defect 101 using the implant 1 is performed. These treatments are called “bone defect reconstruction”.

  As shown in FIGS. 1 and 2, the implant 1 is composed of a plate-shaped member. The implant 1 is manufactured based on bone three-dimensional data acquired in advance, and the bone (hereinafter referred to as “substitution target bone”) present in the bone defect portion 101 of the skull 10 of each patient. ) Is a curved shape substantially corresponding (matched) to the shape. That is, the implant 1 has a back surface 11 located on the brain side when the bone defect portion 101 is compensated and a front surface 12 located on the outside, and the back surface 11 is the back side of the bone to be compensated. The front surface 12 is a curved convex surface corresponding to the front surface of the bone to be compensated. And in a bone defect part reconstruction technique, the implant 1 of such a shape can cover the bone defect part 101 from the outer side, and can compensate the bone defect part 101 concerned.

  Note that the size of the implant 1 in plan view shown in FIG. 3 is preferably designed to be, for example, 3 mm or more and 10 mm or less larger than the size of the bone defect portion 101, and more preferably 5 mm or more and 8 mm or less. .

  Moreover, it does not specifically limit as a constituent material of the implant 1, For example, although a ceramic material, resin, or a metal material can be used, it is preferable that it is a metal material especially. If it is a metal material, the skull plate can be formed very thin, so even if it is installed so as to cover the skull plate in the bone defect part, there is no influence on the appearance after the operation.

  Examples of the ceramic material include various materials, and bioceramics such as alumina, zirconia, and calcium phosphate compounds are particularly preferable. Among these, a calcium phosphate compound is particularly preferable as a constituent material of the implant 1 because it has excellent biocompatibility.

  Examples of the calcium phosphate compound include apatites such as hydroxyapatite, fluorapatite, and carbonate apatite, dicalcium phosphate, tricalcium phosphate, tetracalcium phosphate, octacalcium phosphate, and the like. Species or a combination of two or more can be used. Of these calcium phosphate compounds, those having a Ca / P ratio of 1.0 to 2.0 are preferably used.

  Of such calcium phosphate compounds, hydroxyapatite is more preferable. Hydroxyapatite has an excellent biocompatibility because it has the same structure as the mineral main component of bone. Further, the fusion between the implant 1 itself and the skull 10 can be expected.

  The implant 1 may be a dense body or a porous body, but is preferably a porous body. By constituting the implant 1 with a porous body, it is possible to invade osteoblasts into the implant 1 and perform osteogenesis in the implant 1. In particular, the implant 1 is mainly composed of hydroxyapatite. When configured, it is possible to expect reliable fusion between the implant 1 itself and the skull 10.

Various materials can be used as the metal material, and titanium or a titanium alloy is particularly preferable. Such materials also have biocompatibility and are extremely low in harm to living organisms. Further, the thickness t 1 of the implant 1, can be made thinner than the case of constituting a ceramic material. Thereby, the weight reduction of the implant 1 can be achieved. The thickness t 1, not particularly limited, for example, preferably 1mm or less, 0.5 mm or more, more preferably 0.8mm or less.

  In addition, as a constituent material of the implant 1, a composite material of a ceramic material and a metal material having a low biological harm such as titanium can be used.

  Further, a “3D printer” that employs an additive manufacturing method can be used for manufacturing the implant 1.

  As described above, the size of the implant 1 is slightly larger than the size of the bone defect portion 101. Moreover, the implant 1 is comprised by the curved board member, and the surface 11 of the back side is a curved concave surface curved intricately corresponding to the skull surface with which the implant 1 overlaps. For this reason, when performing the bone defect reconstruction, if the bone defect 101 is covered with the implant 1 and cannot be accurately positioned, a space may be formed between the implant 1 and the skull 10. Further, for example, depending on the location of the bone defect portion 101, the implant 1 slides on the skull 10 and a positional deviation may occur, which may be fixed as it is. Further, since the implant 1 is opaque and does not have transparency, the surgeon cannot visually recognize the position of the bone defect portion 101 through the implant 1 and does not notice the positional deviation.

Therefore, the implant 1 is configured to include a positioning unit 2 that performs positioning with the bone defect 101 while covering the bone defect 101. In this positioning, the implant 1 is finely adjusted on the skull 10 on the basis of the position of the contour of the bone defect portion 101. Depending on the shape of the cut surface 102 generated when the bone defect portion 101 is formed, the contour of the bone defect portion 101 (cut surface 102) includes a brain-side contour OL 1 and an outer contour OL 2 . (See Fig. 2). And, in this position, using a contour OL 2 as a reference.

  As shown in FIG. 3, the positioning portion 2 has three positioning holes 21. Hereinafter, the positioning holes 21a, the positioning holes 21b, and the positioning holes 21c may be sequentially referred to from the left side in FIG. The number of positioning holes 21 formed is three in the configuration shown in FIG. 3, but is not limited thereto, and may be one, two, four or more, for example.

These positioning holes 21 are through holes formed by machining the implant 1 in the thickness direction of the implant 1. Alternatively, when a 3D printer is used, if it is manufactured after adding through-hole data, a step of performing machining later can be omitted. And the formation position of each positioning hole 21 is determined based on the position data of the contour OL 2 among the three-dimensional data of the bone acquired in advance. Accordingly, when the implant 1 is positioned on the bone defect portion 101 and the position of the implant 1 is finely adjusted in order to position the implant 1 with respect to the bone defect portion 101, the positioning is performed via each positioning hole 21. it is possible to visually recognize the position of the contour OL 2 of the bone defect 101 Te (see FIG. 3). This all conditions outline OL 2 from the positioning hole 21 is visible, bone defect 101 is included inside of the implant 1 in a plan view, a proper positioning state.

In this way, when positioning the implant 1 in the bone defect reconstruction, if the positioning hole 21 that functions as a window that can visually recognize the contour OL 2 of the bone defect 101 is used, the correct position of the contour OL 2 is used. Can be grasped. Thereby, the installation of the implant 1 in the bone defect portion 101, that is, the positional relationship between the implant 1 and the bone defect portion 101 can be accurately and quickly set to the state shown in FIG. 3 suitable for the bone defect portion reconstruction. .

As shown in FIG. 3, the shape of each positioning hole 21 is a long shape along a part of the contour OL 2 in a plan view of the implant 1. Thereby, the length of the part of the visible contour OL 2 per positioning hole 21 can be ensured as long as possible, and thus the implant 1 can be positioned accurately. . In the configuration shown in FIG. 3, the width of the positioning hole 21 is gradually decreased from the center portion in the longitudinal direction of the positioning hole 21 toward both end sides. May be constant.

Of the positioning holes 21 a to 21 c, the positioning hole 21 a and the positioning hole 21 c are disposed substantially symmetrically with respect to the center O 1 in plan view of the implant 1. Thereby, the positioning hole 21a and the positioning hole 21c can be arranged as far apart as possible. In general, in positioning of two members, it is preferable that two reference points of one member are aligned with two points separated as much as possible. In the present embodiment, positioning of the bone defect 101 and the implant 1 skull 10 is the outline OL 2 corresponding to the reference line, combined with the positioning hole 21a corresponding to the two points and the positioning hole 21c This is a preferable positioning mode.

Further, as shown in FIG. 3, the positioning holes 21a~ positioning holes 21c are localized in one direction (upper side in FIG. 3) with respect to the center O 1. Thus, in the positioned state, the width W 13 of the overlapping portion 13 overlaps the skull 10 of the implant 1 (hatched portions in FIG. 3), on the side where the positioning holes 21a~ positioning hole 21c is unevenly distributed The average and the average on the other side will be different. In the present embodiment, the former are wider than the latter, the overlap portion 13 can be divided into a significant portion 131 of the width W 13 becomes larger, and the small width portion 132 having a width W 13 becomes small.

  And the fixing | fixed part 3 can be provided in the large part 131. FIG. The fixing part 3 is a part where the positioned implant 1 is fixed to the skull 10.

  As shown in FIG. 3, the fixing portion 3 has twelve fixing holes 31 that are circular in a plan view. These fixing holes 31 are arranged at intervals along the belt-like large portion 131. The number of fixing holes 31 formed is 12 in the configuration shown in FIG. 3, but is not limited to this, and at least one is sufficient, and may be appropriately changed depending on, for example, the shape and size of the implant 1. it can.

  Similar to the positioning holes 21, these fixing holes 31 are through-holes that are formed through the implant 1 in the thickness direction by machining. Bolts 9 can be inserted into the fixing holes 31. And the implant 1 in a positioning state can be fixed to the skull 10 via this bolt 9 (refer FIG. 2).

  When fixing the implant 1, the bolts 9 may be inserted into all the fixing holes 31, but depending on the shape and size of the implant 1, some of the fixing holes 31 are fixed holes. The bolt 9 can also be inserted through 31.

Second Embodiment
FIG. 4 is a plan view showing a second embodiment of the implant of the present invention.

  Hereinafter, the second embodiment of the implant of the present invention will be described with reference to this figure, but the description will focus on differences from the above-described embodiment, and the description of the same matters will be omitted.

  The present embodiment is the same as the first embodiment except that the number and shape of the positioning holes are different.

As shown in FIG. 4, in this embodiment, ten positioning holes 22 are formed in the implant 1. Hereinafter, “positioning hole 22a”, “positioning hole 22b”, “positioning hole 22c”, “positioning hole 22d”, and “positioning hole 22e” from the leftmost positioning hole 22 in FIG. 4 clockwise. "Positioning hole 22f", "positioning hole 22g", "positioning hole 22h", "positioning hole 22i", and "positioning hole 22j". These positioning holes 22 are spaced around the entire circumference of the contour OL 2. Further, the positioning hole 22e and the positioning holes 22a, are substantially symmetrically arranged with respect to the center O 1, and the positioning hole 22g and the positioning hole 22b, it is substantially symmetrically disposed about the center O 1, positioning the hole 22c and the positioning hole 22h, almost symmetrically arranged with respect to the center O 1, and the positioning holes 22i and the positioning hole 22 d, and is substantially symmetrically disposed about the center O 1.

With the positioning holes 22 as described above, the contour OL 2 can be confirmed with a large number of positioning holes 22 having different positions. Thereby, positioning of implant 1 can be performed more correctly.

  In addition, each positioning hole 22 has a circular shape as in the case of the fixing hole 31 in plan view, and the diameter (size) thereof is the same as that of the fixing hole 31. Thereby, when forming the positioning hole 22, it can be formed using, for example, the same drill used for forming the fixing hole 31, and the manufacturing cost of the implant 1 can be suppressed.

<Third Embodiment>
FIG. 5 is a plan view showing a third embodiment of the implant of the present invention.

  Hereinafter, the third embodiment of the implant of the present invention will be described with reference to this figure, but the description will focus on differences from the above-described embodiment, and the description of the same matters will be omitted.

  This embodiment is the same as the second embodiment except that an identification marker is attached.

  As shown in FIG. 5, in this embodiment, an identification marker 41 is attached in the vicinity of the positioning hole 22, and an identification marker 42 is attached in the vicinity of the fixing hole 31. Thereby, the positioning hole 22 and the fixing hole 31 having the same shape and diameter can be reliably identified. By enabling such identification, it is possible to reliably prevent misuse of using the positioning hole 22 as the fixing hole 31 and conversely using the fixing hole 31 as the positioning hole 22. be able to. Therefore, accurate positioning and accurate fixing can be performed, respectively.

  The identification marker 41 includes the direction “Δ” indicated by the identification marker 41 and the use of the positioning hole 22, that is, the meaning “Positioning” of the identification marker 41.

The identification marker 42 includes the direction “Δ” indicated by the identification marker 42 and the usage of the fixing hole 31, that is, the meaning “Fixing” of the identification marker 42.
Moreover, the identification marker 41 and the identification marker 42 are attached by, for example, engraving.

  As mentioned above, although the illustrated embodiment of the implant of the present invention has been described, the present invention is not limited to this, and each part constituting the implant is replaced with an arbitrary structure that can exhibit the same function. can do. Moreover, arbitrary components may be added.

  The implant of the present invention may be a combination of any two or more configurations (features) of the above embodiments.

  In addition, as the bone body in which the implant is used, the skull is given as an example in each of the above embodiments, but is not limited thereto, and examples thereof include a cheekbone and a jawbone.

  Further, a through hole may be further provided inside the positioning hole in plan view. These through-holes can be used, for example, for heat dissipation, for facilitating the processing of the implant, or for lifting the dura and eliminating the gap between the dura and the implant. .

DESCRIPTION OF SYMBOLS 1 Implant 11 Back side surface 12 Front side surface 13 Overlapping part 131 Large part 132 Narrow part 2 Positioning part 21 Positioning hole 21a Positioning hole 21b Positioning hole 21c Positioning hole 22 Positioning hole 22a Positioning hole 22b Positioning hole 22c Positioning hole 22d Positioning hole 22e Positioning hole 22f Positioning hole 22g Positioning hole 22h Positioning hole 22i Positioning hole 22j Positioning hole 3 Fixing portion 31 Fixing hole 41 Identification marker 42 Identification marker 9 Bolt 10 Skull 101 Bone defect 102 Cut surface O 1 center OL 1 outline OL 2 outline t 1 thickness W 13 width

Claims (10)

  1. A plate-like implant covering a bone defect formed by losing a bone body,
    A positioning part for positioning with the bone defect part in a state of covering the bone defect part,
    The positioning portion has at least one positioning hole formed so as to penetrate the implant in the thickness direction, and when performing the positioning, the contour of the bone defect portion is defined through the positioning hole. An implant characterized by being used by visually recognizing a position.
  2.   The implant according to claim 1, wherein a plurality of the positioning holes are arranged at intervals along the contour.
  3.   The implant according to claim 2, wherein two positioning holes among the plurality of positioning holes are arranged symmetrically with respect to a center of the implant in a plan view.
  4.   The implant according to claim 2 or 3, wherein the plurality of positioning holes are unevenly distributed in one direction with respect to a center of the implant in plan view.
  5.   The implant according to claim 4, wherein a width of a portion of the implant that overlaps the bone body in the positioning state in which the positioning is performed is different between a side where the plurality of positioning holes are unevenly distributed and an opposite side thereof.
  6.   The implant according to any one of claims 1 to 5, wherein the positioning hole has a circular shape in a plan view of the implant.
  7.   The implant according to any one of claims 1 to 5, wherein the positioning hole has an elongated shape along a part of the contour in a plan view of the implant.
  8. A fixing portion that is fixed to the bone body in a state of covering the bone defect portion;
    The said fixing | fixed part has at least 1 fixing hole which penetrates the said implant in the thickness direction in the position different from the said positioning hole, and a volt | bolt is penetrated. The implant according to Item.
  9.   The implant according to claim 8, wherein the positioning hole and the fixing hole have the same shape and size, and are each provided with a marker so as to be identifiable.
  10.   The implant according to any one of claims 1 to 9, which is made of a ceramic material or a metal material.
JP2015204408A 2015-10-16 2015-10-16 Implant Pending JP2017074293A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2015204408A JP2017074293A (en) 2015-10-16 2015-10-16 Implant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015204408A JP2017074293A (en) 2015-10-16 2015-10-16 Implant

Publications (1)

Publication Number Publication Date
JP2017074293A true JP2017074293A (en) 2017-04-20

Family

ID=58550456

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015204408A Pending JP2017074293A (en) 2015-10-16 2015-10-16 Implant

Country Status (1)

Country Link
JP (1) JP2017074293A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3174242U (en) * 2011-12-28 2012-03-08 青山国際合同会社 Artificial bone
JP2013505754A (en) * 2009-09-24 2013-02-21 アカデミス・ジーケンハイス・マーストリヒト Cranial implant

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013505754A (en) * 2009-09-24 2013-02-21 アカデミス・ジーケンハイス・マーストリヒト Cranial implant
JP3174242U (en) * 2011-12-28 2012-03-08 青山国際合同会社 Artificial bone

Similar Documents

Publication Publication Date Title
KR100968750B1 (en) Implant for bone fixation
AU2012328382B2 (en) Shoulder base plate coverage and stability
US7742801B2 (en) Planning method and system for free-form implant modification
JP2014511227A (en) Method of manufacturing a lead having segmented electrodes for an electrical stimulation system
US20120289965A1 (en) Customized surgical guides, methods for manufacturing and uses thereof
KR101818682B1 (en) Advanced bone marker and custom implants
JP2014521384A (en) Apparatus and method for providing a reference index to a patient&#39;s tissue
JP4495147B2 (en) Pilot drill, step drill and drill set for dental transplantation technology
US7887587B2 (en) Soft tissue spacer
ES2647919T3 (en) Drug supply implants
JP2007530140A (en) Bone fixation implant
JP4427056B2 (en) Osteosynthesis fixation plate
EP2182893B1 (en) Apparatus for determining pin placement during hip surgery
JP2009056288A (en) Fixation kit for medical or surgical use
JP6490776B2 (en) Orthognathic implant
JP5726418B2 (en) System and method for identifying a target
JP2009521280A (en) Bioresorbable anterior cervical plate fixation system with screw-on retention mechanism
JP5539852B2 (en) Surgical template
JP5523487B2 (en) Method for manufacturing a drilling aid for an implant
JP5411242B2 (en) Surgical stent for dentists and manufacturing method thereof
US20040171929A1 (en) Method and device for determining the contour of a recess in a piece of material
AU2007274381A2 (en) Method for producing a bone prosthesis or a pre-implant simulation, and equipment used
AU2014249415A1 (en) Patient-specific glenoid guide with a reusable guide holder
EP1861031A1 (en) Bone plate
DE602004011868T2 (en) Endoscope

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20180525

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190129

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20190131

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190320

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190903

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190910