JP2016028090A5 - - Google Patents
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- Publication number
- JP2016028090A5 JP2016028090A5 JP2015187057A JP2015187057A JP2016028090A5 JP 2016028090 A5 JP2016028090 A5 JP 2016028090A5 JP 2015187057 A JP2015187057 A JP 2015187057A JP 2015187057 A JP2015187057 A JP 2015187057A JP 2016028090 A5 JP2016028090 A5 JP 2016028090A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament according
- treatment
- emetic
- subject
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 15
- 239000002895 emetic Substances 0.000 claims 4
- 230000000095 emetic Effects 0.000 claims 4
- NTJOBXMMWNYJFB-UHFFFAOYSA-N Amisulpride Chemical compound CCN1CCCC1CNC(=O)C1=CC(S(=O)(=O)CC)=C(N)C=C1OC NTJOBXMMWNYJFB-UHFFFAOYSA-N 0.000 claims 2
- 239000008896 Opium Substances 0.000 claims 2
- 206010047700 Vomiting Diseases 0.000 claims 2
- 229960003036 amisulpride Drugs 0.000 claims 2
- 229960001027 opium Drugs 0.000 claims 2
- 239000003369 serotonin 5-HT3 receptor antagonist Substances 0.000 claims 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N Morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 claims 1
- FELGMEQIXOGIFQ-UHFFFAOYSA-N Ondansetron Chemical compound CC1=NC=CN1CC1C(=O)C(C=2C(=CC=CC=2)N2C)=C2CC1 FELGMEQIXOGIFQ-UHFFFAOYSA-N 0.000 claims 1
- 229960005343 Ondansetron Drugs 0.000 claims 1
- 229940078646 Other antiemetics in ATC Drugs 0.000 claims 1
- 230000001154 acute Effects 0.000 claims 1
- 230000003474 anti-emetic Effects 0.000 claims 1
- 239000002111 antiemetic agent Substances 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 229960004316 cisplatin Drugs 0.000 claims 1
- 238000010253 intravenous injection Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229960005181 morphine Drugs 0.000 claims 1
- 229930014694 morphine Natural products 0.000 claims 1
- 230000003364 opioid Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- LXZZYRPGZAFOLE-UHFFFAOYSA-L transplatin Chemical compound [H][N]([H])([H])[Pt](Cl)(Cl)[N]([H])([H])[H] LXZZYRPGZAFOLE-UHFFFAOYSA-L 0.000 claims 1
Claims (16)
- オピオイドによる吐き気及び嘔吐の症状の治療のための、アミスルプリドを含有する医薬。
- 放射線による吐き気及び嘔吐の症状の治療のための、アミスルプリドを含有する医薬。
- 前記治療の対象者は催吐薬の投与も受けている、請求項1又は2に記載の医薬。
- 前記対象者は癌に罹患しており、前記催吐薬は化学療法薬である、請求項3に記載の医薬。
- 前記催吐薬はシスプラチンである、請求項3又は4に記載の医薬。
- 前記催吐薬はアヘン製剤である、請求項3に記載の医薬。
- 前記アヘン製剤はモルヒネである、請求項6に記載の医薬。
- 静脈注射によって投与される、請求項1〜7のいずれか1項に記載の医薬。
- 前記治療の対象者はヒトである、請求項1〜8のいずれか1項に記載の医薬。
- 単位用量が50mg未満の形態である、請求項1〜9のいずれか1項に記載の医薬。
- 前記単位用量が1〜35mgである、請求項10に記載の医薬。
- 薬学的に許容し得る塩である、請求項1〜11のいずれか1項に記載の医薬。
- 他の鎮吐薬と組み合わせて使用される、請求項1〜12のいずれか1項に記載の医薬。
- 前記他の鎮吐薬は5-HT3受容体拮抗薬である、請求項13に記載の医薬。
- 前記5-HT3受容体拮抗薬はオンダンセトロンである、請求項14に記載の医薬。
- 前記治療の対象者は急性症状を示している、請求項1〜15のいずれか1項に記載の医薬。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1004020.2 | 2010-03-11 | ||
| GBGB1004020.2A GB201004020D0 (en) | 2010-03-11 | 2010-03-11 | New therapeutic use |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012556586A Division JP5886213B2 (ja) | 2010-03-11 | 2011-03-10 | 鎮吐薬としてのアミスルプリドの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016028090A JP2016028090A (ja) | 2016-02-25 |
| JP2016028090A5 true JP2016028090A5 (ja) | 2016-07-28 |
| JP6279526B2 JP6279526B2 (ja) | 2018-02-14 |
Family
ID=42136792
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012556586A Active JP5886213B2 (ja) | 2010-03-11 | 2011-03-10 | 鎮吐薬としてのアミスルプリドの使用 |
| JP2015187057A Active JP6279526B2 (ja) | 2010-03-11 | 2015-09-24 | 鎮吐薬としてのアミスルプリドの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012556586A Active JP5886213B2 (ja) | 2010-03-11 | 2011-03-10 | 鎮吐薬としてのアミスルプリドの使用 |
Country Status (27)
| Country | Link |
|---|---|
| US (11) | US8686019B2 (ja) |
| EP (3) | EP2544657B1 (ja) |
| JP (2) | JP5886213B2 (ja) |
| KR (1) | KR101738201B1 (ja) |
| CN (1) | CN102892407B (ja) |
| AU (1) | AU2011225898B2 (ja) |
| BR (1) | BR112012022746B1 (ja) |
| CA (1) | CA2792392C (ja) |
| CY (3) | CY1115485T1 (ja) |
| DK (3) | DK2796171T3 (ja) |
| EA (1) | EA030335B1 (ja) |
| ES (3) | ES2496099T3 (ja) |
| GB (1) | GB201004020D0 (ja) |
| HK (1) | HK1179152A1 (ja) |
| HR (3) | HRP20140745T1 (ja) |
| HU (1) | HUE037088T2 (ja) |
| IL (1) | IL221746A (ja) |
| LT (1) | LT2796171T (ja) |
| MX (3) | MX370629B (ja) |
| NO (1) | NO2796171T3 (ja) |
| NZ (1) | NZ602279A (ja) |
| PL (3) | PL2796171T3 (ja) |
| PT (3) | PT2796171T (ja) |
| RS (3) | RS53466B (ja) |
| SI (3) | SI2796171T1 (ja) |
| SM (2) | SMT201400126B (ja) |
| WO (1) | WO2011110854A2 (ja) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201004020D0 (en) | 2010-03-11 | 2010-04-21 | Acacia Pharma Ltd | New therapeutic use |
| CN104435861A (zh) * | 2014-12-22 | 2015-03-25 | 济南伟传信息技术有限公司 | 一种治疗妊娠剧吐的茶 |
| GB201506116D0 (en) * | 2015-04-10 | 2015-05-27 | Acacia Pharma Ltd | Kit and combination therapy for nausea and vomiting |
| WO2017040848A1 (en) | 2015-09-02 | 2017-03-09 | California Institute Of Technology | Method and apparatus for the spectroscopic detection of low concentrations of hydrogen sulfide gas |
| GB201618425D0 (en) * | 2016-11-01 | 2016-12-14 | Acacia Pharma Ltd | method |
| GB201702250D0 (en) * | 2017-02-10 | 2017-03-29 | Acacia Pharma Ltd | Method |
| KR20200110317A (ko) | 2017-12-05 | 2020-09-23 | 선오비온 파마슈티컬스 인코포레이티드 | 결정형 및 이의 제조 방법 |
| CN112118838A (zh) | 2017-12-05 | 2020-12-22 | 赛诺维信制药公司 | 非外消旋混合物及其用途 |
| JP2022535894A (ja) * | 2019-06-04 | 2022-08-10 | サノビオン ファーマシューティカルズ インク | 放出調節製剤およびその使用 |
| SG11202113266YA (en) | 2019-06-04 | 2021-12-30 | Sunovion Pharmaceuticals Inc | Modified release formulations and uses thereof |
| KR20230035095A (ko) | 2020-07-06 | 2023-03-10 | 아카시아 파마 리미티드 | 수술 후 오심 및 구토의 치료법 |
| WO2023179542A1 (en) | 2022-03-21 | 2023-09-28 | Gasherbrum Bio , Inc. | 5,8-dihydro-1,7-naphthyridine derivatives as glp-1 agonists for the treatment of diabetes |
| WO2023198140A1 (en) | 2022-04-14 | 2023-10-19 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| WO2024125602A1 (en) | 2022-12-15 | 2024-06-20 | Gasherbrum Bio, Inc. | Salts and solid forms of a compound having glp-1 agonist activity |
| WO2024131869A1 (en) | 2022-12-22 | 2024-06-27 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| WO2024138048A1 (en) | 2022-12-22 | 2024-06-27 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| WO2024169952A1 (en) | 2023-02-16 | 2024-08-22 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2415099A1 (fr) | 1978-01-20 | 1979-08-17 | Ile De France | Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes |
| US6169094B1 (en) * | 1998-07-14 | 2001-01-02 | Sanofi-Synthelabo | Compositions of (S) (-)-amisulpride |
| DE10163421A1 (de) * | 2001-12-21 | 2003-07-31 | Gruenenthal Gmbh | Verwendung von (+)-(1S,2S)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)phenol als Antiemetikum |
| DE102005013726A1 (de) * | 2005-03-22 | 2006-09-28 | Grünenthal GmbH | Transdermale therapeutische Systeme mit verbesserter Verträglichkeit |
| GB0506800D0 (en) * | 2005-04-04 | 2005-05-11 | Merck Sharp & Dohme | New uses |
| WO2007067714A2 (en) * | 2005-12-08 | 2007-06-14 | The Mclean Hospital Corporation | Treatment of sequelae of psychiatric disorders |
| ES2550035T3 (es) * | 2006-01-27 | 2015-11-04 | Adare Pharmaceuticals, Inc. | Sistemas de administración de fármacos que comprenden un agente de bloqueo selectivo de la serotonina 5-HT3 débilmente básico y ácidos orgánicos |
| WO2007096489A1 (fr) * | 2006-02-17 | 2007-08-30 | Trimaran Limited | Nouvelles compositions pharmaceutiques destinees a optimiser des traitements de substitution et elargir la pharmacopee au traitement global des addictions |
| US7825156B2 (en) * | 2007-02-02 | 2010-11-02 | Copharms | Method of treating bipolar depression with a benzamide derivative |
| JP5714910B2 (ja) * | 2008-01-09 | 2015-05-07 | チャールストン ラボラトリーズ，インコーポレイテッド | 薬学的組成物 |
| WO2009126931A2 (en) * | 2008-04-11 | 2009-10-15 | Xvasive, Inc. | Combination therapy for bipolar disorder |
| GB201004020D0 (en) * | 2010-03-11 | 2010-04-21 | Acacia Pharma Ltd | New therapeutic use |
-
2010
- 2010-03-11 GB GBGB1004020.2A patent/GB201004020D0/en not_active Ceased
-
2011
- 2011-03-10 LT LTEP14173186.9T patent/LT2796171T/lt unknown
- 2011-03-10 MX MX2015003664A patent/MX370629B/es unknown
- 2011-03-10 PT PT141731869T patent/PT2796171T/pt unknown
- 2011-03-10 MX MX2012010411A patent/MX2012010411A/es active IP Right Grant
- 2011-03-10 EP EP11709793.1A patent/EP2544657B1/en active Active
- 2011-03-10 RS RS20140410A patent/RS53466B/en unknown
- 2011-03-10 RS RS20140411A patent/RS53467B/en unknown
- 2011-03-10 JP JP2012556586A patent/JP5886213B2/ja active Active
- 2011-03-10 SI SI201131446T patent/SI2796171T1/en unknown
- 2011-03-10 PT PT121880470T patent/PT2567690E/pt unknown
- 2011-03-10 ES ES12188047.0T patent/ES2496099T3/es active Active
- 2011-03-10 NO NO14173186A patent/NO2796171T3/no unknown
- 2011-03-10 WO PCT/GB2011/050472 patent/WO2011110854A2/en active Application Filing
- 2011-03-10 PL PL14173186T patent/PL2796171T3/pl unknown
- 2011-03-10 RS RS20180349A patent/RS57032B1/sr unknown
- 2011-03-10 EA EA201290833A patent/EA030335B1/ru unknown
- 2011-03-10 CA CA2792392A patent/CA2792392C/en active Active
- 2011-03-10 ES ES11709793.1T patent/ES2496092T3/es active Active
- 2011-03-10 KR KR1020127024111A patent/KR101738201B1/ko active IP Right Grant
- 2011-03-10 HU HUE14173186A patent/HUE037088T2/hu unknown
- 2011-03-10 NZ NZ602279A patent/NZ602279A/en unknown
- 2011-03-10 DK DK14173186.9T patent/DK2796171T3/en active
- 2011-03-10 AU AU2011225898A patent/AU2011225898B2/en active Active
- 2011-03-10 PL PL11709793T patent/PL2544657T3/pl unknown
- 2011-03-10 PT PT117097931T patent/PT2544657E/pt unknown
- 2011-03-10 EP EP12188047.0A patent/EP2567690B1/en active Active
- 2011-03-10 CN CN201180018552.XA patent/CN102892407B/zh not_active Ceased
- 2011-03-10 PL PL12188047T patent/PL2567690T3/pl unknown
- 2011-03-10 DK DK11709793.1T patent/DK2544657T3/da active
- 2011-03-10 BR BR112012022746-7A patent/BR112012022746B1/pt active IP Right Grant
- 2011-03-10 SI SI201130237T patent/SI2567690T1/sl unknown
- 2011-03-10 ES ES14173186.9T patent/ES2665418T3/es active Active
- 2011-03-10 DK DK12188047.0T patent/DK2567690T3/da active
- 2011-03-10 EP EP14173186.9A patent/EP2796171B1/en active Active
- 2011-03-10 SI SI201130236T patent/SI2544657T1/sl unknown
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2012
- 2012-07-26 US US13/559,253 patent/US8686019B2/en active Active
- 2012-07-26 US US13/559,168 patent/US9084765B2/en active Active
- 2012-09-02 IL IL221746A patent/IL221746A/en active IP Right Grant
- 2012-09-07 MX MX2019015396A patent/MX2019015396A/es unknown
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2013
- 2013-05-22 HK HK13106057.2A patent/HK1179152A1/zh unknown
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2014
- 2014-02-04 US US14/172,194 patent/US9119836B2/en active Active
- 2014-08-01 HR HRP20140745AT patent/HRP20140745T1/hr unknown
- 2014-08-01 HR HRP20140744AT patent/HRP20140744T1/hr unknown
- 2014-08-14 CY CY20141100656T patent/CY1115485T1/el unknown
- 2014-08-14 CY CY20141100657T patent/CY1115487T1/el unknown
- 2014-09-10 SM SM201400126T patent/SMT201400126B/xx unknown
- 2014-09-10 SM SM201400127T patent/SMT201400127B/xx unknown
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2015
- 2015-07-29 US US14/812,148 patent/US9545426B2/en active Active
- 2015-09-24 JP JP2015187057A patent/JP6279526B2/ja active Active
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2016
- 2016-12-09 US US15/374,174 patent/US9889118B2/en active Active
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2017
- 2017-10-23 US US15/790,481 patent/US10085970B2/en active Active
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2018
- 2018-03-14 HR HRP20180436TT patent/HRP20180436T1/hr unknown
- 2018-04-18 CY CY20181100416T patent/CY1120170T1/el unknown
- 2018-08-20 US US16/105,268 patent/US10525033B2/en active Active
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2019
- 2019-11-27 US US16/697,986 patent/US20200093792A1/en not_active Abandoned
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2020
- 2020-09-08 US US17/013,987 patent/US20210228543A1/en not_active Abandoned
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2022
- 2022-06-07 US US17/834,000 patent/US20220296570A1/en not_active Abandoned
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2023
- 2023-01-11 US US18/095,612 patent/US20230144973A1/en active Pending
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