|
US3361742A
(en)
|
1964-12-07 |
1968-01-02 |
Hoffmann La Roche |
5-oxo-1h-pyrrolo-[2, 1-c][1, 4]-benzodiazepin-2-crylamides
|
|
US3523941A
(en)
|
1967-03-06 |
1970-08-11 |
Hoffmann La Roche |
Benzodiazepine compounds and process for their preparation
|
|
US3524849A
(en)
|
1967-10-27 |
1970-08-18 |
Hoffmann La Roche |
Process for the preparation of pyrrolo-benzodiazepine acrylamides and intermediates useful therein
|
|
IL33558A
(en)
|
1968-12-30 |
1973-10-25 |
Fujisawa Pharmaceutical Co |
Antibiotic pyrrolo-benzodiazepine compound,its derivatives and processes for their production
|
|
DE1965304A1
(de)
|
1968-12-30 |
1970-07-23 |
Fujisawa Pharmaceutical Co |
Benzdiazepinon-Verbindungen und Verfahren zu ihrer Herstellung
|
|
JPS4843755B1
(US07794700-20100914-C00152.png)
|
1969-06-26 |
1973-12-20 |
|
|
|
JPS6053033B2
(ja)
|
1976-12-28 |
1985-11-22 |
財団法人微生物化学研究会 |
新制癌抗生物質マゼスラマイシン及びその製造方法
|
|
JPS585916B2
(ja)
|
1977-12-27 |
1983-02-02 |
株式会社ミドリ十字 |
新規ベンゾジアゼピン系化合物
|
|
JPS5615289A
(en)
|
1979-07-17 |
1981-02-14 |
Green Cross Corp:The |
Novel benzodiazepinnbased compound 3
|
|
JPS57131791A
(en)
|
1980-12-31 |
1982-08-14 |
Fujisawa Pharmaceut Co Ltd |
Benzodiazepine derivative and its preparation
|
|
CA1185602A
(en)
|
1981-02-27 |
1985-04-16 |
Emilio Kyburz |
Imidazodiazepines
|
|
CA1173441A
(en)
|
1981-02-27 |
1984-08-28 |
Hoffmann-La Roche Limited |
Imidazodiazepines
|
|
CA1184175A
(en)
|
1981-02-27 |
1985-03-19 |
Walter Hunkeler |
Imidazodiazepines
|
|
JPS58180487A
(ja)
|
1982-04-16 |
1983-10-21 |
Kyowa Hakko Kogyo Co Ltd |
抗生物質ｄｃ−８１およびその製造法
|
|
US4427588A
(en)
|
1982-11-08 |
1984-01-24 |
Bristol-Myers Company |
Process for conversion of oxotomaymycin to tomaymycin
|
|
US4427587A
(en)
|
1982-11-10 |
1984-01-24 |
Bristol-Myers Company |
Total synthesis of antitumor antibiotics BBM-2040A and BBM-2040B
|
|
JPS59152329A
(ja)
|
1983-02-17 |
1984-08-31 |
Green Cross Corp:The |
局所障害抑制剤
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
FR2586683B1
(fr)
|
1985-08-29 |
1988-07-01 |
Centre Nat Rech Scient |
Nouveaux derives de neothramycine, leur procede de preparation et leur application en tant que medicaments
|
|
US5583024A
(en)
|
1985-12-02 |
1996-12-10 |
The Regents Of The University Of California |
Recombinant expression of Coleoptera luciferase
|
|
JP2660201B2
(ja)
|
1988-08-05 |
1997-10-08 |
塩野義製薬株式会社 |
新規ピロロ［１，４］ベンゾジアゼピン誘導体および老人性痴呆薬
|
|
WO1991002536A1
(en)
|
1989-08-23 |
1991-03-07 |
Scripps Clinic And Research Foundation |
Compositions and methods for detection and treatment of epstein-barr virus infection and immune disorders
|
|
JPH053790A
(ja)
|
1990-04-19 |
1993-01-14 |
Fujisawa Pharmaceut Co Ltd |
デヒドロペプチダーゼ−ｉ
|
|
US5256643A
(en)
|
1990-05-29 |
1993-10-26 |
The Government Of The United States |
Human cripto protein
|
|
AU9016591A
(en)
|
1990-10-25 |
1992-05-26 |
Tanox Biosystems, Inc. |
Glycoproteins associated with membrane-bound immunoglobulins as antibody targets on B cells
|
|
EP0577752B2
(en)
|
1991-03-29 |
2007-07-11 |
Genentech, Inc. |
Human pf4a receptors and their use
|
|
US5543503A
(en)
|
1991-03-29 |
1996-08-06 |
Genentech Inc. |
Antibodies to human IL-8 type A receptor
|
|
US5440021A
(en)
|
1991-03-29 |
1995-08-08 |
Chuntharapai; Anan |
Antibodies to human IL-8 type B receptor
|
|
FR2676230B1
(fr)
|
1991-05-07 |
1993-08-27 |
Centre Nat Rech Scient |
Nouveaux derives de pyrrolo [1,4]-benzodiazepines, leur procede de preparation et medicaments les contenant.
|
|
JP3050424B2
(ja)
|
1991-07-12 |
2000-06-12 |
塩野義製薬株式会社 |
ヒトエンドセリンリセプター
|
|
US5264557A
(en)
|
1991-08-23 |
1993-11-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Polypeptide of a human cripto-related gene, CR-3
|
|
US5362852A
(en)
|
1991-09-27 |
1994-11-08 |
Pfizer Inc. |
Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties
|
|
US6153408A
(en)
|
1991-11-15 |
2000-11-28 |
Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale |
Altered major histocompatibility complex (MHC) determinant and methods of using the determinant
|
|
US5976551A
(en)
|
1991-11-15 |
1999-11-02 |
Institut Pasteur And Institut Nationale De La Sante Et De La Recherche Medicale |
Altered major histocompatibility complex (MHC) determinant and method of using the determinant
|
|
GB9205051D0
(en)
|
1992-03-09 |
1992-04-22 |
Cancer Res Campaign Tech |
Pyrrolobenzodiazepine derivatives,their preparation,and compositions containing them
|
|
FR2696176B1
(fr)
|
1992-09-28 |
1994-11-10 |
Synthelabo |
Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
|
|
IL107366A
(en)
|
1992-10-23 |
2003-03-12 |
Chugai Pharmaceutical Co Ltd |
Genes coding for megakaryocyte potentiator
|
|
US5644033A
(en)
|
1992-12-22 |
1997-07-01 |
Health Research, Inc. |
Monoclonal antibodies that define a unique antigen of human B cell antigen receptor complex and methods of using same for diagnosis and treatment
|
|
US5801005A
(en)
|
1993-03-17 |
1998-09-01 |
University Of Washington |
Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
|
|
US5869445A
(en)
|
1993-03-17 |
1999-02-09 |
University Of Washington |
Methods for eliciting or enhancing reactivity to HER-2/neu protein
|
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
|
GB9316162D0
(en)
|
1993-08-04 |
1993-09-22 |
Zeneca Ltd |
Fungicides
|
|
US5773223A
(en)
|
1993-09-02 |
1998-06-30 |
Chiron Corporation |
Endothelin B1, (ETB1) receptor polypeptide and its encoding nucleic acid methods, and uses thereof
|
|
EP0647450A1
(en)
|
1993-09-09 |
1995-04-12 |
BEHRINGWERKE Aktiengesellschaft |
Improved prodrugs for enzyme mediated activation
|
|
US5750370A
(en)
|
1995-06-06 |
1998-05-12 |
Human Genome Sciences, Inc. |
Nucleic acid encoding human endothlein-bombesin receptor and method of producing the receptor
|
|
JPH08336393A
(ja)
|
1995-04-13 |
1996-12-24 |
Mitsubishi Chem Corp |
光学活性なγ−置換−β−ヒドロキシ酪酸エステルの製造法
|
|
US5707829A
(en)
|
1995-08-11 |
1998-01-13 |
Genetics Institute, Inc. |
DNA sequences and secreted proteins encoded thereby
|
|
US20020193567A1
(en)
|
1995-08-11 |
2002-12-19 |
Genetics Institute, Inc. |
Secreted proteins and polynucleotides encoding them
|
|
JP3646191B2
(ja)
|
1996-03-19 |
2005-05-11 |
大塚製薬株式会社 |
ヒト遺伝子
|
|
US6218519B1
(en)
|
1996-04-12 |
2001-04-17 |
Pro-Neuron, Inc. |
Compounds and methods for the selective treatment of cancer and bacterial infections
|
|
SK157498A3
(en)
|
1996-05-17 |
1999-10-08 |
Schering Corp |
Isolated and recombinant nucleic acid, bas-1 protein or peptide thereof, and agent, antibody, expression vector, host cell and method of their use
|
|
CA2264227A1
(en)
|
1996-09-27 |
1998-04-02 |
Raymond A. Firestone |
Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells
|
|
US6759509B1
(en)
|
1996-11-05 |
2004-07-06 |
Bristol-Myers Squibb Company |
Branched peptide linkers
|
|
US5945511A
(en)
|
1997-02-20 |
1999-08-31 |
Zymogenetics, Inc. |
Class II cytokine receptor
|
|
US20030185830A1
(en)
|
1997-02-25 |
2003-10-02 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of prostate cancer
|
|
US7033827B2
(en)
|
1997-02-25 |
2006-04-25 |
Corixa Corporation |
Prostate-specific polynucleotide compositions
|
|
ATE268340T1
(de)
|
1997-03-10 |
2004-06-15 |
Univ California |
Prostata stammzell-antigen (psca)
|
|
US6261791B1
(en)
|
1997-03-10 |
2001-07-17 |
The Regents Of The University Of California |
Method for diagnosing cancer using specific PSCA antibodies
|
|
US6541212B2
(en)
|
1997-03-10 |
2003-04-01 |
The Regents Of The University Of California |
Methods for detecting prostate stem cell antigen protein
|
|
US6555339B1
(en)
|
1997-04-14 |
2003-04-29 |
Arena Pharmaceuticals, Inc. |
Non-endogenous, constitutively activated human protein-coupled receptors
|
|
US6319688B1
(en)
|
1997-04-28 |
2001-11-20 |
Smithkline Beecham Corporation |
Polynucleotide encoding human sodium dependent phosphate transporter (IPT-1)
|
|
WO1998051824A1
(en)
|
1997-05-15 |
1998-11-19 |
Abbott Laboratories |
Reagents and methods useful for detecting disease of the urinary tract
|
|
WO1998051805A1
(en)
|
1997-05-15 |
1998-11-19 |
Abbott Laboratories |
Reagents and methods useful for detecting diseases of the prostate
|
|
US6602677B1
(en)
|
1997-09-19 |
2003-08-05 |
Promega Corporation |
Thermostable luciferases and methods of production
|
|
US20030060612A1
(en)
|
1997-10-28 |
2003-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20020034749A1
(en)
|
1997-11-18 |
2002-03-21 |
Billing-Medel Patricia A. |
Reagents and methods useful for detecting diseases of the breast
|
|
US6110695A
(en)
|
1997-12-02 |
2000-08-29 |
The Regents Of The University Of California |
Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1
|
|
AU762991B2
(en)
|
1998-03-13 |
2003-07-10 |
Burnham Institute, The |
Molecules that home to various selected organs or tissues
|
|
CA2331846C
(en)
|
1998-05-13 |
2010-01-12 |
Epimmune Inc. |
Expression vectors for stimulating an immune response and methods of using the same
|
|
US20020187472A1
(en)
|
2001-03-09 |
2002-12-12 |
Preeti Lal |
Steap-related protein
|
|
US20030064397A1
(en)
|
1998-05-22 |
2003-04-03 |
Incyte Genomics, Inc. |
Transmembrane protein differentially expressed in prostate and lung tumors
|
|
TWI253935B
(en)
|
1998-05-22 |
2006-05-01 |
Daiichi Seiyaku Co |
Drug complex
|
|
DE69920228T2
(de)
|
1998-07-08 |
2005-01-27 |
E-Ink Corp., Cambridge |
Verfahren zur verbesserung der farbwiedergabe in elektrophoretischen vorrichtungen, welche mikrokapseln verwenden
|
|
WO2000012130A1
(en)
|
1998-08-27 |
2000-03-09 |
Smithkline Beecham Corporation |
Rp105 agonists and antagonists
|
|
GB9818732D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
|
GB9818731D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Compounds
|
|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
|
DE69907977T2
(de)
|
1998-08-27 |
2004-07-22 |
Spirogen Ltd., Ryde |
Pyrrolobenzodiazepine
|
|
JP4689781B2
(ja)
|
1998-09-03 |
2011-05-25 |
独立行政法人科学技術振興機構 |
アミノ酸輸送蛋白及びその遺伝子
|
|
WO2000020579A1
(en)
|
1998-10-02 |
2000-04-13 |
Mcmaster University |
Spliced form of erbb-2/neu oncogene
|
|
WO2001057188A2
(en)
|
2000-02-03 |
2001-08-09 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
US6468546B1
(en)
|
1998-12-17 |
2002-10-22 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of ovarian cancer
|
|
US6962980B2
(en)
|
1999-09-24 |
2005-11-08 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6858710B2
(en)
|
1998-12-17 |
2005-02-22 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20020119158A1
(en)
|
1998-12-17 |
2002-08-29 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030091580A1
(en)
|
2001-06-18 |
2003-05-15 |
Mitcham Jennifer L. |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030190669A1
(en)
|
1998-12-30 |
2003-10-09 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
DE69939553D1
(de)
|
1998-12-30 |
2008-10-23 |
Beth Israel Hospital |
Charakterisierung der proteinfamilie von soc/crac kalziumkanälen
|
|
ES2348708T3
(es)
|
1999-01-29 |
2010-12-13 |
Corixa Corporation |
Proteinas de fusion de her-2/neu.
|
|
GB9905124D0
(en)
|
1999-03-05 |
1999-04-28 |
Smithkline Beecham Biolog |
Novel compounds
|
|
AU3395900A
(en)
|
1999-03-12 |
2000-10-04 |
Human Genome Sciences, Inc. |
Human lung cancer associated gene sequences and polypeptides
|
|
US7312303B2
(en)
|
1999-05-11 |
2007-12-25 |
Genentech, Inc. |
Anti-PRO4980 antibodies
|
|
US6268488B1
(en)
|
1999-05-25 |
2001-07-31 |
Barbas, Iii Carlos F. |
Prodrug activation using catalytic antibodies
|
|
AU4952600A
(en)
|
1999-06-03 |
2000-12-28 |
Takeda Chemical Industries Ltd. |
Screening method with the use of cd100
|
|
DK2283867T3
(da)
|
1999-06-25 |
2014-06-10 |
Immunogen Inc |
Fremgangsmåder til behandling ved anvendelse af anti-ErbB antistof-maytansinoidkonjugater
|
|
US6302318B1
(en)
|
1999-06-29 |
2001-10-16 |
General Electric Company |
Method of providing wear-resistant coatings, and related articles
|
|
US20030119113A1
(en)
|
1999-07-20 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7297770B2
(en)
|
1999-08-10 |
2007-11-20 |
Genentech, Inc. |
PRO6496 polypeptides
|
|
US7294696B2
(en)
|
1999-08-17 |
2007-11-13 |
Genentech Inc. |
PRO7168 polypeptides
|
|
US6909006B1
(en)
|
1999-08-27 |
2005-06-21 |
Spirogen Limited |
Cyclopropylindole derivatives
|
|
JP3951035B2
(ja)
|
1999-09-01 |
2007-08-01 |
ジェネンテック・インコーポレーテッド |
分泌及び膜貫通ポリペプチドとそれをコードしている核酸
|
|
US20030206918A1
(en)
|
1999-09-10 |
2003-11-06 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030129192A1
(en)
|
1999-09-10 |
2003-07-10 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030232056A1
(en)
|
1999-09-10 |
2003-12-18 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
CA2387108A1
(en)
|
1999-10-29 |
2001-06-07 |
Genentech, Inc. |
Anti-prostate stem cell antigen (psca) antibody compositions and methods of use
|
|
AU2048901A
(en)
|
1999-11-29 |
2001-06-04 |
Trustees Of Columbia University In The City Of New York, The |
Isolation of five novel genes coding for new Fc receptors-type melanoma involved in the pathogenesis of lymphoma/melanoma
|
|
EP1248800A2
(en)
|
1999-11-30 |
2002-10-16 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of breast cancer
|
|
WO2001041787A1
(en)
|
1999-12-10 |
2001-06-14 |
Epimmune Inc. |
INDUCING CELLULAR IMMUNE RESPONSES TO HER2/neu USING PEPTIDE AND NUCLEIC ACID COMPOSITIONS
|
|
NZ502058A
(en)
|
1999-12-23 |
2003-11-28 |
Ovita Ltd |
Isolated mutated nucleic acid molecule for regulation of ovulation rate
|
|
DE60040240D1
(de)
|
1999-12-23 |
2008-10-23 |
Zymogenetics Inc |
Löslicher interleukin-20 rezeptor
|
|
US6610286B2
(en)
|
1999-12-23 |
2003-08-26 |
Zymogenetics, Inc. |
Method for treating inflammation using soluble receptors to interleukin-20
|
|
DK1616575T3
(da)
|
1999-12-23 |
2012-09-10 |
Zymogenetics Inc |
Fremgangsmåde til behandling af inflammation
|
|
US7608681B2
(en)
|
1999-12-24 |
2009-10-27 |
Genentech, Inc. |
Methods and compositions for prolonging elimination half-times of bioactive compounds
|
|
US20040001827A1
(en)
|
2002-06-28 |
2004-01-01 |
Dennis Mark S. |
Serum albumin binding peptides for tumor targeting
|
|
US7294695B2
(en)
|
2000-01-20 |
2007-11-13 |
Genentech, Inc. |
PRO10268 polypeptides
|
|
EP1252294A2
(en)
|
2000-01-21 |
2002-10-30 |
Corixa Corporation |
Compounds and methods for prevention and treatment of her-2/neu associated malignancies
|
|
US20030224379A1
(en)
|
2000-01-21 |
2003-12-04 |
Tang Y. Tom |
Novel nucleic acids and polypeptides
|
|
US20030219806A1
(en)
|
2000-02-22 |
2003-11-27 |
Millennium Pharmaceuticals, Inc. |
Novel 18607, 15603, 69318, 12303, 48000, 52920, 5433, 38554, 57301, 58324, 55063, 52991, 59914, 59921 and 33751 molecules and uses therefor
|
|
US20020142377A1
(en)
|
2000-02-22 |
2002-10-03 |
Glucksmann Maria Alexandra |
18607, a novel human calcium channel
|
|
US20040052793A1
(en)
|
2001-02-22 |
2004-03-18 |
Carter Paul J. |
Caspase activivated prodrugs therapy
|
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
US20040005561A1
(en)
|
2000-03-01 |
2004-01-08 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
EP1261743A2
(en)
|
2000-03-07 |
2002-12-04 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
EP1268526A4
(en)
|
2000-03-24 |
2004-09-08 |
Fahri Saatcioglu |
NEW PROSTATE-SPECIFIC AND TESTIS-SPECIFIC NUCLEIC ACID MOLECULES, POLYPEPTIDES AND DIAGNOSTIC AND THERAPEUTIC PROCEDURES
|
|
JP2003530325A
(ja)
|
2000-03-31 |
2003-10-14 |
イーペーエフ ファルマシューティカルス ゲゼルシャフト ミット ベシュレンクテル ハフツング |
好ましくは特異的ケモカインレセプター分析、及びケモカインレセプター／リガンド相互作用の助けによる、腫瘍及び炎症細胞の細胞表面プロテオームの調査、並びに腫瘍疾患及び炎症性疾患の治療のための診断薬及び薬剤
|
|
AU2001253140A1
(en)
|
2000-04-03 |
2001-10-15 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Tumor markers in ovarian cancer
|
|
CN1420929A
(zh)
|
2000-04-07 |
2003-05-28 |
阿瑞那制药公司 |
非内源性组成型活化的已知g蛋白偶联受体
|
|
US20030119115A1
(en)
|
2000-05-17 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
AU2001263105A1
(en)
|
2000-05-18 |
2001-11-26 |
Lexicon Genetics Incorporated |
Human semaphorin homologs and polynucleotides encoding the same
|
|
AU2001274888A1
(en)
|
2000-05-19 |
2001-12-03 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
WO2001094641A2
(en)
|
2000-06-09 |
2001-12-13 |
Idec Pharmaceuticals Corporation |
Gene targets and ligands that bind thereto for treatment and diagnosis of ovarian carcinomas
|
|
EP1297130A2
(en)
|
2000-06-16 |
2003-04-02 |
Incyte Genomics, Inc. |
G-protein coupled receptors
|
|
AU2001273151A1
(en)
|
2000-06-30 |
2002-01-14 |
Incyte Genomics, Inc. |
Human extracellular matrix and cell adhesion polypeptides
|
|
JP2004502417A
(ja)
|
2000-06-30 |
2004-01-29 |
アムジェン インコーポレーテッド |
Ｂ７様分子およびその使用
|
|
WO2002002587A1
(en)
|
2000-06-30 |
2002-01-10 |
Human Genome Sciences, Inc. |
B7-like polynucleotides, polypeptides, and antibodies
|
|
AU2002214531A1
(en)
|
2000-07-03 |
2002-01-30 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
US20040044179A1
(en)
|
2000-07-25 |
2004-03-04 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US6891030B2
(en)
|
2000-07-27 |
2005-05-10 |
Mayo Foundation For Medical Education And Research |
T-cell immunoregulatory molecule
|
|
JP2004505617A
(ja)
|
2000-07-28 |
2004-02-26 |
ヴィッセンバッハ，ウルリヒ |
Ｔｒｐ８、Ｔｒｐ９およびＴｒｐ１０、癌の新規マーカー
|
|
US7229623B1
(en)
|
2000-08-03 |
2007-06-12 |
Corixa Corporation |
Her-2/neu fusion proteins
|
|
MXPA03001389A
(es)
|
2000-08-14 |
2004-05-04 |
Corixa Corp |
Composiciones y metodos para la terapia y diagnostico de malignidades asociadas con her-2/neu.
|
|
AU2001283360A1
(en)
|
2000-08-14 |
2002-02-25 |
Corixa Corporation |
Methods for diagnosis and therapy of hematological and virus-associated malignancies
|
|
GB0020953D0
(en)
|
2000-08-24 |
2000-10-11 |
Smithkline Beecham Biolog |
Vaccine
|
|
JP2004520806A
(ja)
|
2000-08-24 |
2004-07-15 |
ジェネンテック・インコーポレーテッド |
腫瘍の診断と治療のための組成物と方法
|
|
AU2001290548A1
(en)
|
2000-09-11 |
2002-03-26 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
ES2267814T3
(es)
|
2000-09-15 |
2007-03-16 |
Zymogenetics, Inc. |
Metodo para tratar la inflamacion.
|
|
US6613567B1
(en)
|
2000-09-15 |
2003-09-02 |
Isis Pharmaceuticals, Inc. |
Antisense inhibition of Her-2 expression
|
|
US20030119121A1
(en)
|
2000-09-15 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
AU9272401A
(en)
|
2000-09-18 |
2002-03-26 |
Biogen Inc |
Cripto mutant and uses thereof
|
|
UA83458C2
(uk)
|
2000-09-18 |
2008-07-25 |
Байоджен Айдек Ма Інк. |
Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
|
|
WO2002030894A2
(en)
|
2000-09-19 |
2002-04-18 |
Taiho Pharmaceutical Co., Ltd. |
Compositions and methods of the use thereof achiral analogues of cc-1065 and the duocarmycins
|
|
JP2005506033A
(ja)
|
2000-10-13 |
2005-03-03 |
イーオーエス バイオテクノロジー インコーポレイテッド |
前立腺癌の診断法、前立腺癌モジュレータースクリーニングの組成物及び方法
|
|
JP2004516826A
(ja)
|
2000-11-07 |
2004-06-10 |
ザイモジェネティクス，インコーポレイティド |
ヒト腫瘍壊死因子受容体
|
|
US20020150573A1
(en)
|
2000-11-10 |
2002-10-17 |
The Rockefeller University |
Anti-Igalpha-Igbeta antibody for lymphoma therapy
|
|
US20040018194A1
(en)
|
2000-11-28 |
2004-01-29 |
Francisco Joseph A. |
Recombinant anti-CD30 antibodies and uses thereof
|
|
WO2002061087A2
(en)
|
2000-12-19 |
2002-08-08 |
Lifespan Biosciences, Inc. |
Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides
|
|
EP1357828A2
(en)
|
2001-01-12 |
2003-11-05 |
University of Medicine and Dentistry of New Jersey |
Bone morphogenetic protein-2 in the treatment and diagnosis of cancer
|
|
US20030119126A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030119125A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
AU2002245317A1
(en)
|
2001-01-24 |
2002-08-06 |
Protein Design Labs |
Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer
|
|
WO2002060317A2
(en)
|
2001-01-30 |
2002-08-08 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of pancreatic cancer
|
|
US20040170994A1
(en)
|
2001-02-12 |
2004-09-02 |
Callen David Frederick |
DNA sequences for human tumour suppressor genes
|
|
AU2002258518A1
(en)
|
2001-03-14 |
2002-09-24 |
Millennium Pharmaceuticals, Inc. |
Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
|
|
EP1243276A1
(en)
|
2001-03-23 |
2002-09-25 |
Franciscus Marinus Hendrikus De Groot |
Elongated and multiple spacers containing activatible prodrugs
|
|
AU2002311787A1
(en)
|
2001-03-28 |
2002-10-15 |
Zycos Inc. |
Translational profiling
|
|
US6362331B1
(en)
|
2001-03-30 |
2002-03-26 |
Council Of Scientific And Industrial Research |
Process for the preparation of antitumor agents
|
|
WO2003008537A2
(en)
|
2001-04-06 |
2003-01-30 |
Mannkind Corporation |
Epitope sequences
|
|
US6820011B2
(en)
|
2001-04-11 |
2004-11-16 |
The Regents Of The University Of Colorado |
Three-dimensional structure of complement receptor type 2 and uses thereof
|
|
WO2002083866A2
(en)
|
2001-04-17 |
2002-10-24 |
The Board Of Trustees Of The University Of Arkansas |
Repeat sequences of the ca125 gene and their use for diagnostic and therapeutic interventions
|
|
AU2002309583A1
(en)
|
2001-04-18 |
2002-11-05 |
Protein Desing Labs, Inc. |
Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
|
|
JP4307845B2
(ja)
|
2001-04-26 |
2009-08-05 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
Ｃｒｉｐｔｏをブロックする抗体およびその使用
|
|
WO2003083041A2
(en)
|
2002-03-22 |
2003-10-09 |
Biogen, Inc. |
Cripto-specific antibodies
|
|
US6884869B2
(en)
|
2001-04-30 |
2005-04-26 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
|
EP1988097A1
(en)
|
2001-05-09 |
2008-11-05 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of prostate cancer
|
|
WO2002092836A2
(en)
|
2001-05-11 |
2002-11-21 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acid sequence encoding ovarian antigen, ca125, and uses thereof
|
|
DE60234202D1
(de)
|
2001-05-24 |
2009-12-10 |
Zymogenetics Inc |
Taci-immunoglobulin-fusionsproteine
|
|
US7157558B2
(en)
|
2001-06-01 |
2007-01-02 |
Genentech, Inc. |
Polypeptide encoded by a polynucleotide overexpresses in tumors
|
|
WO2002098358A2
(en)
|
2001-06-04 |
2002-12-12 |
Eos Biotechnology, Inc. |
Methods of diagnosis and treatment of androgen-dependent prostate cancer, prostate cancer undergoing androgen-withdrawal, and androgen-independent prostate cancer
|
|
WO2003000842A2
(en)
|
2001-06-04 |
2003-01-03 |
Curagen Corporation |
Novel proteins and nucleic acids encoding same
|
|
AU2002320264B2
(en)
|
2001-06-05 |
2008-05-01 |
Exelixis, Inc. |
GFATs as modifiers of the p53 pathway and methods of use
|
|
US20050112568A1
(en)
|
2001-06-05 |
2005-05-26 |
Lori Friedman |
Dgks as modifiers of the p53 pathwha and methods of use
|
|
US7235358B2
(en)
|
2001-06-08 |
2007-06-26 |
Expression Diagnostics, Inc. |
Methods and compositions for diagnosing and monitoring transplant rejection
|
|
WO2002101075A2
(en)
|
2001-06-13 |
2002-12-19 |
Millennium Pharmaceuticals, Inc. |
Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
|
|
EP1517998A2
(en)
|
2001-06-18 |
2005-03-30 |
EOS Biotechnology, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
US7189507B2
(en)
|
2001-06-18 |
2007-03-13 |
Pdl Biopharma, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
US7705120B2
(en)
|
2001-06-21 |
2010-04-27 |
Millennium Pharmaceuticals, Inc. |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
|
|
WO2003002717A2
(en)
|
2001-06-28 |
2003-01-09 |
Schering Corporation |
Biological activity of ak155
|
|
WO2003004529A2
(en)
|
2001-07-02 |
2003-01-16 |
Licentia Ltd. |
Ephrin-tie receptor materials and methods
|
|
US20040076955A1
(en)
|
2001-07-03 |
2004-04-22 |
Eos Biotechnology, Inc. |
Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer
|
|
WO2003003984A2
(en)
|
2001-07-05 |
2003-01-16 |
Curagen Corporation |
Novel proteins and nucleic acids encoding same
|
|
WO2003055439A2
(en)
|
2001-07-18 |
2003-07-10 |
The Regents Of The University Of California |
Her2/neu target antigen and use of same to stimulate an immune response
|
|
WO2003009814A2
(en)
|
2001-07-25 |
2003-02-06 |
Millennium Pharmaceuticals, Inc. |
Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer
|
|
EA200601861A1
(ru)
|
2001-08-03 |
2007-02-27 |
Дженентек, Инк. |
ПОЛИПЕПТИДЫ TACIs И BR3 И ИХ ПРИМЕНЕНИЕ
|
|
CA2457819A1
(en)
|
2001-08-14 |
2003-02-27 |
The General Hospital Corporation |
Nucleic acid and amino acid sequences involved in pain
|
|
US20030092013A1
(en)
|
2001-08-16 |
2003-05-15 |
Vitivity, Inc. |
Diagnosis and treatment of vascular disease
|
|
AU2002313559A1
(en)
|
2001-08-23 |
2003-03-10 |
Oxford Biomedica (Uk) Limited |
Genes
|
|
AU2002357643A1
(en)
|
2001-08-29 |
2003-04-14 |
Vanderbilt University |
The human mob-5 (il-24) receptors and uses thereof
|
|
US20030124579A1
(en)
|
2001-09-05 |
2003-07-03 |
Eos Biotechnology, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
JP2005505271A
(ja)
|
2001-09-06 |
2005-02-24 |
アジェンシス， インコーポレイテッド |
癌の処置および検出において有用なｓｔｅａｐ−１と名称が与えられる核酸および対応するタンパク質
|
|
JP2005518782A
(ja)
|
2001-09-17 |
2005-06-30 |
プロテイン デザイン ラブス， インコーポレイテッド |
ガンの診断方法、ガンのモジュレータのスクリーニング組成物及び方法
|
|
CA2460120A1
(en)
|
2001-09-18 |
2003-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20050004017A1
(en)
|
2001-09-18 |
2005-01-06 |
Yuval Reiss |
Methods and compositions for treating hcap associated diseases
|
|
CA2460621A1
(en)
|
2001-09-19 |
2003-03-27 |
Nuvelo, Inc. |
Novel nucleic acids and polypeptides
|
|
WO2003026577A2
(en)
|
2001-09-24 |
2003-04-03 |
Seattle Genetics, Inc. |
P-amidobenzylethers in drug delivery agents
|
|
US7091186B2
(en)
|
2001-09-24 |
2006-08-15 |
Seattle Genetics, Inc. |
p-Amidobenzylethers in drug delivery agents
|
|
WO2003026493A2
(en)
|
2001-09-28 |
2003-04-03 |
Bing Yang |
Diagnosis and treatment of diseases caused by mutations in cd72
|
|
AU2002362436A1
(en)
|
2001-10-03 |
2003-04-14 |
Rigel Pharmaceuticals, Inc. |
Modulators of lymphocyte activation and migration
|
|
WO2003029421A2
(en)
|
2001-10-03 |
2003-04-10 |
Origene Technologies, Inc. |
Regulated breast cancer genes
|
|
US20050123925A1
(en)
|
2002-11-15 |
2005-06-09 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
EP1578385A4
(en)
|
2001-10-19 |
2011-11-09 |
Genentech Inc |
COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF INFLAMMATORY INTESTINAL DISEASES
|
|
US7825089B2
(en)
|
2001-10-24 |
2010-11-02 |
National Jewish Health |
Three-dimensional structures of TALL-1 and its cognate receptors and modified proteins and methods related thereto
|
|
KR100996226B1
(ko)
|
2001-10-31 |
2010-11-24 |
유니버시티 오브 노스 텍사스 헬스 사이언스 센터 |
뼈 형태발생 단백질(ｂｍｐ), ｂｍｐ 수용체 및 ｂｍｐ결합 단백질 및 녹내장 진단 및 치료에서 그의 용도
|
|
US20030232350A1
(en)
|
2001-11-13 |
2003-12-18 |
Eos Biotechnology, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
|
WO2003042661A2
(en)
|
2001-11-13 |
2003-05-22 |
Protein Design Labs, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
|
WO2003043583A2
(en)
|
2001-11-20 |
2003-05-30 |
Seattle Genetics, Inc. |
Treatment of immunological disorders using anti-cd30 antibodies
|
|
WO2003045422A1
(en)
|
2001-11-29 |
2003-06-05 |
Genset S.A. |
Agonists and antagonists of prolixin for the treatment of metabolic disorders
|
|
WO2003048202A2
(en)
|
2001-12-03 |
2003-06-12 |
Asahi Kasei Pharma Corporation |
Nf-kappab activating genes
|
|
JP4723810B2
(ja)
|
2001-12-03 |
2011-07-13 |
アレクシオン ファーマシューティカルズ， インコーポレイテッド |
ハイブリッド抗体
|
|
WO2003054152A2
(en)
|
2001-12-10 |
2003-07-03 |
Nuvelo, Inc. |
Novel nucleic acids and polypeptides
|
|
US20030134790A1
(en)
|
2002-01-11 |
2003-07-17 |
University Of Medicine And Dentistry Of New Jersey |
Bone Morphogenetic Protein-2 And Bone Morphogenetic Protein-4 In The Treatment And Diagnosis Of Cancer
|
|
WO2003060612A1
(fr)
|
2002-01-16 |
2003-07-24 |
Japan Science And Technology Agency |
Dispositif de reproduction holographique d'images mobiles et dispositif de reproduction holographique d'images mobiles couleur
|
|
US7452675B2
(en)
|
2002-01-25 |
2008-11-18 |
The Queen's Medical Center |
Methods of screening for TRPM4b modulators
|
|
EP1476120B1
(en)
|
2002-02-21 |
2010-09-29 |
Duke University |
Treatment methods using anti-cd22 antibodies
|
|
CA2476518A1
(en)
|
2002-02-22 |
2003-09-04 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
AU2003224638A1
(en)
|
2002-03-01 |
2003-09-16 |
Exelixis, Inc. |
PDPK1s AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
|
|
US20050220798A1
(en)
|
2002-06-04 |
2005-10-06 |
Reinhard Ebner |
Cancer-linked gene as target for chemotherapy
|
|
US6660856B2
(en)
|
2002-03-08 |
2003-12-09 |
Kaohsiung Medical University |
Synthesis of pyrrolo[2,1-c][1,4]benzodiazepine analogues
|
|
EP2258712A3
(en)
|
2002-03-15 |
2011-05-04 |
Multicell Immunotherapeutics, Inc. |
Compositions and Methods to Initiate or Enhance Antibody and Major-histocompatibility Class I or Class II-restricted T Cell Responses by Using Immunomodulatory, Non-coding RNA Motifs
|
|
WO2004000997A2
(en)
|
2002-03-19 |
2003-12-31 |
Curagen Corporation |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
|
JP2005534286A
(ja)
|
2002-03-21 |
2005-11-17 |
サネシス ファーマシューティカルズ， インコーポレイテッド |
キナーゼインヒビターの同定
|
|
US7193069B2
(en)
|
2002-03-22 |
2007-03-20 |
Research Association For Biotechnology |
Full-length cDNA
|
|
WO2003089624A2
(en)
|
2002-03-25 |
2003-10-30 |
Uab Research Foundation |
Fc receptor homolog, reagents, and uses thereof
|
|
AU2003222103A1
(en)
|
2002-03-28 |
2003-10-13 |
Idec Pharmaceuticals Corporation |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of colon carcinomas
|
|
US20030194704A1
(en)
|
2002-04-03 |
2003-10-16 |
Penn Sharron Gaynor |
Human genome-derived single exon nucleic acid probes useful for gene expression analysis two
|
|
EP1572916A4
(en)
|
2002-04-05 |
2007-05-30 |
Agensys Inc |
NUCLEIC ACID AND CORRESPONDING PROTEIN WITH THE NAME 98P4B6, SUITABLE FOR THE TREATMENT AND DETECTION OF CANCER
|
|
WO2003087768A2
(en)
|
2002-04-12 |
2003-10-23 |
Mitokor |
Targets for therapeutic intervention identified in the mitochondrial proteome
|
|
KR20040101502A
(ko)
|
2002-04-16 |
2004-12-02 |
제넨테크, 인크. |
종양의 진단 및 치료 방법 및 이를 위한 조성물
|
|
AU2003239158A1
(en)
|
2002-04-17 |
2003-11-03 |
Baylor College Of Medicine |
Aib1 as a prognostic marker and predictor of resistance to encocrine therapy
|
|
WO2003093444A2
(en)
|
2002-05-03 |
2003-11-13 |
Incyte Corporation |
Transporters and ion channels
|
|
AU2003229294A1
(en)
|
2002-05-15 |
2003-12-02 |
Avalon Pharmaceuticals |
Cancer-linked gene as target for chemotherapy
|
|
US20030224454A1
(en)
|
2002-05-30 |
2003-12-04 |
Ryseck Rolf Peter |
Human solute carrier family 7, member 11 (hSLC7A11)
|
|
AU2003240495A1
(en)
|
2002-06-04 |
2003-12-19 |
Incyte Corporation |
Diagnostics markers for lung cancer
|
|
AU2003242633A1
(en)
|
2002-06-06 |
2003-12-22 |
Molecular Engines Laboratories |
Dudulin genes, non-human animal model: uses in human hematological disease
|
|
KR101031025B1
(ko)
|
2002-06-06 |
2011-04-25 |
온코세라피 사이언스 가부시키가이샤 |
사람 결장암에 관계하는 유전자 및 폴리펩티드
|
|
CA2488629A1
(en)
|
2002-06-07 |
2003-12-18 |
Avalon Pharmaceuticals, Inc |
Cancer-linked gene as target for chemotherapy
|
|
WO2003105758A2
(en)
|
2002-06-12 |
2003-12-24 |
Avalon Pharmaceuticals, Inc. |
Cancer-linked gene as target for chemotherapy
|
|
JP2005533794A
(ja)
|
2002-06-18 |
2005-11-10 |
アーケミックス コーポレイション |
アプタマー−毒素分子およびこれを使用する方法
|
|
US20040249130A1
(en)
|
2002-06-18 |
2004-12-09 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
|
AU2003245615A1
(en)
|
2002-06-20 |
2004-01-06 |
The Regents Of The University Of California |
Compositions and methods for modulating lymphocyte activity
|
|
EP1534331B1
(en)
|
2002-06-21 |
2014-10-29 |
Johns Hopkins University School of Medicine |
Membrane associated tumor endothelium markers
|
|
DE10229834A1
(de)
|
2002-07-03 |
2004-01-29 |
Zinser Textilmaschinen Gmbh |
Streckwerk für Spinnmaschinen mit nachgeordneter Verdichtungsvorrichtung
|
|
AU2003281515A1
(en)
|
2002-07-19 |
2004-02-09 |
Cellzome Ag |
Protein complexes of cellular networks underlying the development of cancer and other diseases
|
|
AU2003256836A1
(en)
|
2002-07-25 |
2004-02-16 |
Genentech, Inc. |
Taci antibodies and uses thereof
|
|
CA2494104A1
(en)
|
2002-07-31 |
2004-04-22 |
Seattle Genetics, Inc. |
Anti-cd20 antibody-drug conjugates for the treatment of cancer and immune disorders
|
|
PT1545613E
(pt)
|
2002-07-31 |
2011-09-27 |
Seattle Genetics Inc |
Conjugados de auristatina e sua utilização para tratamento do cancro, de uma doença autoimune ou de uma doença infecciosa
|
|
WO2004015426A1
(en)
|
2002-08-06 |
2004-02-19 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with human cxc chemokine receptor 5(cxcr5)
|
|
JP2004121218A
(ja)
|
2002-08-06 |
2004-04-22 |
Jenokkusu Soyaku Kenkyusho:Kk |
気管支喘息または慢性閉塞性肺疾患の検査方法
|
|
CA2495389A1
(en)
|
2002-08-19 |
2004-02-26 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
WO2004020583A2
(en)
|
2002-08-27 |
2004-03-11 |
Bristol-Myers Squibb Company |
Polynucleotide predictor set for identifying protein tyrosine kinase modulators
|
|
WO2004020595A2
(en)
|
2002-08-29 |
2004-03-11 |
Five Prime Therapeutics, Inc. |
Novel human polypeptides encoded by polynucleotides
|
|
US20050271615A1
(en)
|
2002-08-30 |
2005-12-08 |
Doron Shabat |
Self-immolative dendrimers releasing many active moieties upon a single activating event
|
|
AU2002951346A0
(en)
|
2002-09-05 |
2002-09-26 |
Garvan Institute Of Medical Research |
Diagnosis of ovarian cancer
|
|
MXPA05002455A
(es)
|
2002-09-06 |
2005-06-03 |
Mannkind Corp |
Secuencias de epitopes.
|
|
US20060134109A1
(en)
|
2002-09-09 |
2006-06-22 |
Nura Inc. |
G protein coupled receptors and uses thereof
|
|
JP2004113151A
(ja)
|
2002-09-27 |
2004-04-15 |
Sankyo Co Ltd |
癌遺伝子及びその用途
|
|
AU2003278002A1
(en)
|
2002-10-03 |
2004-04-23 |
Mcgill Univeristy |
Antibodies and cyclic peptides which bind cea (carcinoembryonic antigen) and their use as cancer therapeutics
|
|
WO2004032842A2
(en)
|
2002-10-04 |
2004-04-22 |
Van Andel Research Institute |
Molecular sub-classification of kidney tumors and the discovery of new diagnostic markers
|
|
US20040138269A1
(en)
|
2002-10-11 |
2004-07-15 |
Sugen, Inc. |
Substituted pyrroles as kinase inhibitors
|
|
CA2503748A1
(en)
|
2002-11-08 |
2004-05-27 |
Genentech, Inc. |
Compositions and methods for the treatment of natural killer cell related diseases
|
|
AU2003295511A1
(en)
|
2002-11-13 |
2004-06-03 |
Genentech, Inc. |
Methods and compositions for diagnosing dysplasia
|
|
CA2506080A1
(en)
|
2002-11-14 |
2004-05-27 |
Syntarga B.V. |
Prodrugs built as multiple self-elimination-release spacers
|
|
GB0226593D0
(en)
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
|
ES2392511T3
(es)
|
2002-11-15 |
2012-12-11 |
Musc Foundation For Research Development |
Moduladores de complemento dianas sobre el receptor 2 de complemento
|
|
KR101329843B1
(ko)
|
2002-11-15 |
2013-11-14 |
젠맵 에이/에스 |
Ｃｄ25에 대한 인간 모노클로날 항체
|
|
MXPA05005237A
(es)
|
2002-11-15 |
2005-08-16 |
Univ Arkansas |
Gen ca125 y su uso para diagnostico e intervenciones terapeuticas.
|
|
US20080213166A1
(en)
|
2002-11-20 |
2008-09-04 |
Biogen Idec Inc. |
Novel Gene Targets and Ligands that Bind Thereto for Treatment and Diagnosis of Colon Carcinomas
|
|
EP2410332A1
(en)
|
2002-11-21 |
2012-01-25 |
The University Of Utah |
Method for identifying purinergic modulators of the olfactory system
|
|
WO2004048938A2
(en)
|
2002-11-26 |
2004-06-10 |
Protein Design Labs, Inc. |
Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
|
|
WO2004053079A2
(en)
|
2002-12-06 |
2004-06-24 |
Diadexus, Inc. |
Compositions, splice variants and methods relating to ovarian specific genes and proteins
|
|
JP2004198419A
(ja)
|
2002-12-13 |
2004-07-15 |
Bayer Healthcare Llc |
Ｔｉｍｐ１を用いた検出方法
|
|
ES2388280T3
(es)
|
2002-12-20 |
2012-10-11 |
Abbott Biotherapeutics Corp. |
Anticuerpos que reaccionan frente a GPR64 y utilización de los mismos
|
|
WO2004058309A1
(en)
|
2002-12-23 |
2004-07-15 |
Human Genome Sciences, Inc. |
Neutrokine-alpha conjugate, neutrokine-alpha complex, and uses thereof
|
|
WO2004063709A2
(en)
|
2003-01-08 |
2004-07-29 |
Bristol-Myers Squibb Company |
Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators
|
|
WO2004063355A2
(en)
|
2003-01-10 |
2004-07-29 |
Protein Design Labs, Inc. |
Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of matastatic cancer
|
|
US20050227301A1
(en)
|
2003-01-10 |
2005-10-13 |
Polgen |
Cell cycle progression proteins
|
|
EP1583820A4
(en)
|
2003-01-14 |
2007-07-18 |
Bristol Myers Squibb Co |
ASSOCIATED POLYNUCLEOTIDES AND POLYPEPTIDES ASSOCIATED WITH THE NF-KB WAY
|
|
EP1583821A4
(en)
|
2003-01-15 |
2007-07-18 |
Millennium Pharm Inc |
METHODS AND COMPOSITIONS FOR TREATING UROLOGICAL DISORDERS USING GENES 44390, 54181, 211, 5687, 884, 1405, 636, 4421, 5410, 30905, 2045, 16405, 18560, 2047, 33751, 52872, 14063, 20739, 32544, 43239, 44373, 51164, 53010, 16852, 1587, 2207, 22245, 2387, 52908, 69112, 14990, 18547, 115, 579
|
|
EP2196474A3
(en)
|
2003-02-14 |
2010-12-15 |
Sagres Discovery, Inc. |
Therapeutic targets in cancer
|
|
US20030224411A1
(en)
|
2003-03-13 |
2003-12-04 |
Stanton Lawrence W. |
Genes that are up- or down-regulated during differentiation of human embryonic stem cells
|
|
US6884799B2
(en)
|
2003-03-31 |
2005-04-26 |
Council Of Scientific And Industrial Research |
Non-cross-linking pyrrolo[2,1-c][1,4]benzodiazepines and process thereof
|
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
|
GB0416511D0
(en)
|
2003-10-22 |
2004-08-25 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
US7511032B2
(en)
|
2003-10-22 |
2009-03-31 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
|
|
AU2004316290C1
(en)
|
2003-11-06 |
2012-02-02 |
Seagen Inc. |
Monomethylvaline compounds capable of conjugation to ligands
|
|
EP1720908A2
(en)
|
2004-02-17 |
2006-11-15 |
Absalus, Inc. |
Super-humanized antibodies against respiratory syncytial virus
|
|
WO2005082023A2
(en)
|
2004-02-23 |
2005-09-09 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
|
GB0404578D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
EP1720881B9
(en)
|
2004-03-01 |
2013-04-17 |
Spirogen Sàrl |
11-hydroxy-5h-pyrrolo[2,1-c][1,4]benzodiazepin-5-one derivatives as key intermediates for the preparation of c2 substituted pyrrolobenzodiazepins
|
|
GB0404574D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Amino acids
|
|
GB0404577D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
DE102004010943A1
(de)
|
2004-03-03 |
2005-09-29 |
Degussa Ag |
Verfahren zur Herstellung von N-geschützten 4-Ketprolinderivaten
|
|
US7528126B2
(en)
|
2004-03-09 |
2009-05-05 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
|
FR2869231B1
(fr)
|
2004-04-27 |
2008-03-14 |
Sod Conseils Rech Applic |
Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine
|
|
GB0410725D0
(en)
|
2004-05-13 |
2004-06-16 |
Spirogen Ltd |
Pyrrolobenzodiazepine therapeutic agents
|
|
NZ580115A
(en)
|
2004-09-23 |
2010-10-29 |
Genentech Inc |
Cysteine engineered antibody light chains and conjugates
|
|
WO2006068325A2
(en)
|
2004-12-24 |
2006-06-29 |
Showa Denko K. K. |
Production method of thermoelectric semiconductor alloy, thermoelectric conversion module and thermoelectric power generating device
|
|
KR101385886B1
(ko)
|
2005-02-03 |
2014-04-24 |
안티토페 리미티드 |
인간 항체들과 단백질들
|
|
JP5122441B2
(ja)
|
2005-04-19 |
2013-01-16 |
シアトル ジェネティックス， インコーポレイテッド |
ヒト化抗ｃｄ７０結合剤およびその使用
|
|
ES2338696T3
(es)
|
2005-04-21 |
2010-05-11 |
Spirogen Limited |
Pirrolobenzodiazepinas.
|
|
EP1931671B1
(en)
|
2005-10-05 |
2009-04-08 |
Spirogen Limited |
Alkyl 4- [4- (5-oxo-2, 3, 5, 11a-tetrahyd0-5h-pyrr0l0 [2, 1-c][1, 4]benzodiazepine-8-yloxy) -butyrylamino]-1h-pyrrole-2-carboxylate derivatives and related compounds for the treatment of a proliferative disease
|
|
CN101365676B
(zh)
|
2005-10-07 |
2013-09-11 |
埃克塞利希斯股份有限公司 |
作为用于治疗增生性疾病的mek抑制剂的吖丁啶
|
|
EP1966245B1
(en)
|
2005-12-30 |
2011-05-18 |
Merck Patent GmbH |
Anti-cd19 antibodies with reduced immunogenicity
|
|
DK1813614T3
(da)
|
2006-01-25 |
2012-01-23 |
Sanofi Sa |
Cytotoksiske midler, der omfatter nye tomaymycinderivater
|
|
ME00581B
(me)
|
2006-07-18 |
2011-12-20 |
Sanofi Aventis |
Antagonisticna antitijela za tretman kancera polje pronalaska
|
|
DK2383297T5
(da)
|
2006-08-14 |
2022-07-04 |
Xencor Inc |
Optimerede antistoffer rettet mod CD19
|
|
US20080112961A1
(en)
|
2006-10-09 |
2008-05-15 |
Macrogenics, Inc. |
Identification and Engineering of Antibodies with Variant Fc Regions and Methods of Using Same
|
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
ES2523915T5
(es)
|
2006-12-01 |
2022-05-26 |
Seagen Inc |
Agentes de unión a la diana variantes y usos de los mismos
|
|
WO2008087184A2
(en)
*
|
2007-01-17 |
2008-07-24 |
Merck Serono S.A. |
Process for the purification of fc-containing proteins
|
|
AR066476A1
(es)
|
2007-05-08 |
2009-08-19 |
Genentech Inc |
Anticuerpos anti-muc16 disenados con cisteina y conjugaods de anticuerpos y farmacos
|
|
DK2019104T3
(da)
|
2007-07-19 |
2013-12-16 |
Sanofi Sa |
Cytotoksiske midler, der omfatter nye tomaymycinderivater, og terapeutisk anvendelse deraf
|
|
AU2008312457B2
(en)
|
2007-10-19 |
2014-04-17 |
Genentech, Inc. |
Cysteine engineered anti-TENB2 antibodies and antibody drug conjugates
|
|
CA2718942A1
(en)
|
2008-03-18 |
2009-09-24 |
Seattle Genetics, Inc. |
Auristatin drug linker conjugates
|
|
GB0813432D0
(en)
|
2008-07-22 |
2008-08-27 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
EP2349040B9
(en)
|
2008-10-15 |
2014-12-17 |
Zimmer GmbH |
Intramedullary nail
|
|
GB0819097D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
ES2604668T3
(es)
|
2009-02-05 |
2017-03-08 |
Immunogen, Inc. |
Nuevos derivados de benzodiacepina
|
|
BRPI1005984A2
(pt)
|
2009-02-23 |
2016-10-04 |
Glenmark Pharmaceuticals Sa |
anticorpo humanizado ou fragmento do mesmo que se liga ao cd19 humano, acido nucleico isolado, vetor, célula hospedeira, método para produzir um anticorpo humanizado ou fragmento do mesmo que se liga à cd12 humano, composição, imunoconjugado, uso de um anticorpo humanizado ou fragmento do mesmo, artigo de manufatura e kit
|
|
FR2949469A1
(fr)
|
2009-08-25 |
2011-03-04 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application en therapeutique
|
|
MX2012002651A
(es)
|
2009-09-01 |
2012-05-22 |
Abbott Lab |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
|
JP2013505944A
(ja)
|
2009-09-24 |
2013-02-21 |
シアトル ジェネティックス， インコーポレイテッド |
Ｄｒ５リガンド薬物結合体
|
|
US9040526B2
(en)
|
2010-02-09 |
2015-05-26 |
Bristol-Myers Squibb Company |
Benzylpyrrolidinone derivatives as modulators of chemokine receptor activity
|
|
EP2558475A1
(en)
|
2010-04-15 |
2013-02-20 |
Spirogen Sàrl |
Pyrrolobenzodiazepines used to treat proliferative diseases
|
|
WO2011130615A2
(en)
|
2010-04-15 |
2011-10-20 |
Dr. Reddy's Laboratories Ltd. |
Preparation of lacosamide
|
|
GB201006340D0
(en)
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
|
ES2430567T3
(es)
|
2010-04-15 |
2013-11-21 |
Spirogen Sàrl |
Pirrolobenzodiacepinas y conjugados de las mismas
|
|
BR112012026801B8
(pt)
|
2010-04-15 |
2021-05-25 |
Medimmune Ltd |
conjugados de pirrolobenzodiazepina direcionados, composição farmacêutica, uso dos mesmos para tratamento de uma doença proliferativa ou autoimune e ligante de medicamento
|
|
EP3666289A1
(en)
|
2011-02-15 |
2020-06-17 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
EP2751120B1
(en)
|
2011-09-20 |
2018-08-22 |
MedImmune Limited |
Pyrrolobenzodiazepines as unsymmetrical dimeric pbd compounds for inclusion in targeted conjugates
|
|
US9399073B2
(en)
|
2011-10-14 |
2016-07-26 |
Seattle Genetics, Inc. |
Pyrrolobenzodiazepines
|
|
PT2750713E
(pt)
|
2011-10-14 |
2016-01-20 |
Genentech Inc |
Pirrolobenzodiazepinas e conjugados das mesmas
|
|
CN104011018B
(zh)
|
2011-10-14 |
2016-12-14 |
麦迪穆有限责任公司 |
可用于制备吡咯并苯并二氮杂卓的合成方法和中间体
|
|
EA026643B1
(ru)
|
2011-10-14 |
2017-04-28 |
Сиэтл Дженетикс, Инк. |
Пирролбензодиазепины и конъюгаты направленного действия
|
|
US9388187B2
(en)
|
2011-10-14 |
2016-07-12 |
Medimmune Limited |
Pyrrolobenzodiazepines
|
|
WO2013055990A1
(en)
|
2011-10-14 |
2013-04-18 |
Seattle Genetics, Inc. |
Pyrrolobenzodiazepines and targeted conjugates
|
|
EP2869849A1
(en)
|
2012-07-09 |
2015-05-13 |
Genentech, Inc. |
Immunoconjugates comprising anti-cd22 antibodies
|
|
JP2015523380A
(ja)
|
2012-07-09 |
2015-08-13 |
ジェネンテック， インコーポレイテッド |
抗ｃｄ７９ｂ抗体を含む免疫複合体
|
|
RU2015106673A
(ru)
|
2012-08-02 |
2016-09-20 |
Дженентек, Инк. |
Антитела к рецептору эндотелина типа в (etbr) и иммуноконъюгаты
|
|
CA2887897C
(en)
*
|
2012-10-12 |
2020-02-18 |
Adc Therapeutics Sarl |
Pyrrolobenzodiazepine-anti-cd25 antibody conjugates
|
|
JP6367204B2
(ja)
|
2012-10-12 |
2018-08-01 |
メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ |
結合用のピロロベンゾジアゼピン誘導体の合成および中間体
|
|
DK2766048T3
(en)
|
2012-10-12 |
2015-03-02 |
Spirogen Sarl |
PYRROLOBENZODIAZEPINS AND CONJUGATES THEREOF
|
|
PL3470086T3
(pl)
|
2012-10-12 |
2021-05-31 |
Medimmune Limited |
Pirolobenzodiazepiny i ich koniugaty
|
|
CA2901941C
(en)
|
2013-03-13 |
2020-04-07 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
BR112017011111A2
(pt)
*
|
2014-11-25 |
2017-12-26 |
Adc Therapeutics Sa |
conjugados de pirrolobenzodiazepina-anticorpo
|
|
JP7402691B2
(ja)
*
|
2017-04-20 |
2023-12-21 |
アーデーセー セラピューティクス ソシエテ アノニム |
抗ｃｄ２５抗体薬物複合体による併用療法
|
