JP2013534537A - ベンダムスチンの殺菌における改良された方法 - Google Patents

ベンダムスチンの殺菌における改良された方法 Download PDF

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Publication number
JP2013534537A
JP2013534537A JP2013519757A JP2013519757A JP2013534537A JP 2013534537 A JP2013534537 A JP 2013534537A JP 2013519757 A JP2013519757 A JP 2013519757A JP 2013519757 A JP2013519757 A JP 2013519757A JP 2013534537 A JP2013534537 A JP 2013534537A
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JP
Japan
Prior art keywords
bendamustine
solid
pharmaceutically acceptable
acceptable salt
salt form
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Pending
Application number
JP2013519757A
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English (en)
Japanese (ja)
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JP2013534537A5 (https=
Inventor
ワイ． ラベル、レイチェル
アール． パテル、ピーユシュ
Original Assignee
セファロン、インク．
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by セファロン、インク． filed Critical セファロン、インク．
Publication of JP2013534537A publication Critical patent/JP2013534537A/ja
Publication of JP2013534537A5 publication Critical patent/JP2013534537A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/04—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/081—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/087—Particle radiation, e.g. electron-beam, alpha or beta radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2013519757A 2010-07-13 2011-07-12 ベンダムスチンの殺菌における改良された方法 Pending JP2013534537A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36384710P 2010-07-13 2010-07-13
US61/363,847 2010-07-13
PCT/US2011/043614 WO2012009299A1 (en) 2010-07-13 2011-07-12 Improved methods for the sterilization of bendamustine

Publications (2)

Publication Number Publication Date
JP2013534537A true JP2013534537A (ja) 2013-09-05
JP2013534537A5 JP2013534537A5 (https=) 2015-03-12

Family

ID=44510172

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013519757A Pending JP2013534537A (ja) 2010-07-13 2011-07-12 ベンダムスチンの殺菌における改良された方法

Country Status (8)

Country Link
US (1) US20130144068A1 (https=)
EP (1) EP2593144A1 (https=)
JP (1) JP2013534537A (https=)
CN (1) CN103052407A (https=)
AU (1) AU2011279402A1 (https=)
CA (1) CA2804865A1 (https=)
MX (1) MX2013000373A (https=)
WO (1) WO2012009299A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107375965B (zh) * 2017-07-18 2019-02-15 江门华大生物科技有限公司 中药饮片无硫杀虫保藏方法
KR102086318B1 (ko) * 2018-03-12 2020-03-09 주식회사 코스메카코리아 감마선 조사를 통한 유연성을 가지는 고형의 경시적 색변화 하이드로겔 화장료 조성물

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006076620A2 (en) * 2005-01-14 2006-07-20 Cephalon, Inc. Bendamustine pharmaceutical compositions for lyophilisation
WO2010042568A1 (en) * 2008-10-08 2010-04-15 Cephalon, Inc. Processes for the preparation of bendamustine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422068A (en) * 1994-01-05 1995-06-06 Shalaby; Shalaby W. Radiochemical sterilization
CN2225245Y (zh) * 1995-06-20 1996-04-24 鞍山钢铁公司 快速微型固体干热消毒装置
US6632648B1 (en) * 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
CN101366954B (zh) * 2008-09-19 2013-03-20 乐普（北京）医疗器械股份有限公司 一种生物涂层医疗装置的灭菌处理方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006076620A2 (en) * 2005-01-14 2006-07-20 Cephalon, Inc. Bendamustine pharmaceutical compositions for lyophilisation
WO2010042568A1 (en) * 2008-10-08 2010-04-15 Cephalon, Inc. Processes for the preparation of bendamustine

Also Published As

Publication number Publication date
WO2012009299A1 (en) 2012-01-19
CN103052407A (zh) 2013-04-17
CA2804865A1 (en) 2012-01-19
MX2013000373A (es) 2013-02-15
AU2011279402A1 (en) 2013-01-31
US20130144068A1 (en) 2013-06-06
EP2593144A1 (en) 2013-05-22

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