JP2013040137A - Dental glass ionomer cement - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide dental glass ionomer cement which is suitable for temporary adhesion or temporary sealing without using a filler not reacting with polycarboxylic acid or a liquid component not reacting with powder component.SOLUTION: This dental glass ionomer cement is constituted of: first components (1) fluoroaluminosilicate glass powder and (2) powder of a non-glass calcium compound reacting with polycarboxylic acid in the presence of water; and second components (1) polycarboxylic acid and (2) water; wherein the first components may further contain water and a viscosity adjusting material.

Description

  The present invention relates to a glass ionomer cement suitable for temporary sealing and temporary use.

  Dental glass ionomer cement is a dental cement that is used by reacting and curing fluoroaluminosilicate glass powder and polycarboxylic acid in the presence of water. Is translucent and excellent in aesthetics, has excellent adhesion to dental materials such as enamel and dentin, and further, fluoroaluminosilicate glass that is glass powder for glass ionomer cement It is widely used because it has various excellent features such as an anti-cariogenic effect due to fluorine contained in the powder.

  Dental glass ionomer cement with such excellent characteristics is used for filling caries, filling crowns, inlays, bridges and orthodontic bands, lining cavities, root canal sealers, supports. It is used for a wide range of applications in the dental field, such as building a stand and preventive filling. The dental glass ionomer cement is used by mixing and kneading a fluoroaluminosilicate glass powder and an aqueous polycarboxylic acid solution immediately before use, applying the kneaded product to the treatment site, and then curing the kneaded product. Resin-reinforced dental glass ionomer cements containing a polymerizable monomer have also been developed for the purpose of improving the physical strength, particularly the bending strength, of hardened cement bodies.

  However, since conventional dental glass ionomer cements, including resin-reinforced dental glass ionomer cements, were basically intended for permanent restoration, dental glass ionomer cements provide strong mechanical strength. Therefore, it has not been considered to be used for temporary sealing or temporary wearing. That is, when dental glass ionomer cement is used for temporary sealing or temporary attachment of temporary restorations, its high physical properties are an obstacle to removing temporary sealing materials or removing temporary restorations. End up.

  In order to use dental glass ionomer cement for temporary sealing or temporary attachment, there is a powder component that uses a filler that does not react with polycarboxylic acid (see, for example, Patent Document 1). However, the addition of a filler that does not react with the polycarboxylic acid as described above has a drawback that the feeling of kneading deteriorates when the powder component and the liquid component are mixed, and further has the disadvantage of causing poor mixing. .

  Further, since the filler that does not react with the polycarboxylic acid is not fixed to the hardened cement body by ionic bonding, there is a problem that the components of the hardened cement body are dissolved by gradually flowing out in the oral cavity. High hardened body strength is not necessarily required for temporary sealing or temporary application, but dissolution of the components of the cemented hardened body may cause the temporary sealing material to fall off or the temporarily restored material to fall off.

  In addition, in order to use dental glass ionomer cement for temporary sealing or temporary attachment, there is a method using a liquid component that does not react with fluoroaluminosilicate glass powder (see, for example, Patent Documents 2 and 3). However, there is a risk that the liquid component that does not react with the powder component will elute from the cement cured body over time, and in the same way as the above-described method of blending the filler that does not react with the polycarboxylic acid, a partial component of the cement cured body is included. There was a problem that led to proper dissolution.

JP 2002-220314 A JP 2010-030948 A JP 2010-064989 A

  Thus, the present invention has an object to provide a dental glass ionomer cement suitable for temporary sealing and temporary attachment without using a filler that does not react with polycarboxylic acid or a liquid component that does not react with fluoroaluminosilicate glass powder. To do.

  As a result of diligent study to solve the above problems, the present inventors reduced the strength of the hardened cement by adding a non-glass calcium compound capable of reacting with polycarboxylic acid to dental glass ionomer cement, A dental glass ionomer cement was completed, in which the components of the hardened cement were not significantly dissolved.

That is, the present invention
First component 1) Fluoroaluminosilicate glass powder 2) Powder of non-glass calcium compound that reacts with polycarboxylic acid in the presence of water Second component 1) Polycarboxylic acid 2) Water Dental glass ionomer cement.

  In the dental glass ionomer cement according to the present invention, the compressive strength of the cement cured body is reduced so as to be suitable for temporary sealing and temporary application, and the components of the cement cured body are not significantly dissolved. It is a dental glass ionomer cement that is ideal for temporary wear.

As the main component of the first component of the dental glass ionomer cement according to the present invention, fluoroaluminosilicate glass powder is used. As the fluoroaluminosilicate glass powder, those conventionally used in dental cement can be used, and contain Al ³⁺ , Si ⁴⁺ , F ⁻ , O ²⁻ as main components, and further Sr ²⁺ and / or Ca ^2+. An aluminosilicate glass powder containing N is preferable, and the ratio of the main components is particularly Al ³⁺ : 10 to 21% by weight, Si ⁴⁺ : 9 to 21% by weight, F ⁻ : 1 to 20% by weight, Sr, based on the total weight of the glass. The sum of ²⁺ and Ca ²⁺ is preferably 10 to 34% by weight. The fluoroaluminosilicate glass powder is desirably 30 to 85% by weight in the cement kneaded product. If it is 30% by weight or less, the strength of the cured product is weak, and if it is 85% by weight or more, the viscosity of the kneaded product is too high and kneading is difficult.

  Non-glassy calcium compounds that react with polycarboxylic acids in the presence of water are calcium acetate, calcium borate, calcium carbide, calcium carbonate, calcium chloride, calcium citrate, calcium dihydrogen phosphate, calcium hydrogen phosphate, phosphoric acid Tricalcium, calcium fluoride, calcium hydroxide, calcium hypophosphite, calcium iodide, calcium oxalate, calcium oxide, calcium sulfate, calcium sulfide, tricalcium silicate, dicalcium silicate, calcium aluminate, calcium aluminoferrite, tartaric acid Calcium, calcium adipate, calcium laurate, calcium stearate, calcium 12-hydroxystearate, calcium palmitate, calcium lactate, calcium montanate, potassium behenate Examples include calcium, calcium benzoate, calcium terephthalate, calcium gluconate, caseinfophosphopeptide-amorphous calcium phosphate, caseinfophosphopeptide-amorphous calcium fluoride phosphate, and use in combination of two or more. You can also. Of these, calcium fluoride and caseinfophosphopeptide-amorphous calcium phosphate are most preferable from the viewpoint of biological safety.

  The blending amount of the non-glassy calcium compound that reacts with the polycarboxylic acid in the presence of water is 1% by weight to 30% by weight in the first component. If it is less than 1% by weight, the effect of reducing the strength of the hardened cement body is poor, and if it exceeds 30% by weight, the strength of the hardened cement body tends to be excessively lowered.

  The polycarboxylic acid is a polymer of α, β-unsaturated monocarboxylic acid or α, β-unsaturated dicarboxylic acid, such as acrylic acid, methacrylic acid, 2-chloroacrylic acid, aconitic acid, mesaconic acid, A homopolymer or copolymer of maleic acid, itaconic acid, fumaric acid, glutaconic acid, citraconic acid or the like. These copolymers may be a copolymer of α, β-unsaturated carboxylic acids, or a copolymer with a component copolymerizable with an α, β-unsaturated carboxylic acid. In this case, the proportion of α, β-unsaturated carboxylic acid is preferably 50% or more. Examples of the copolymerizable component include acrylamide, acrylonitrile, methacrylic acid esters, acrylates, vinyl chloride, allyl chloride, and vinyl acetate. Among these α, β-unsaturated carboxylic acid polymers, homopolymers or copolymers of acrylic acid or itaconic acid are particularly preferred. These polycarboxylic acids are components that react with the aforementioned fluoroaluminosilicate glass powder in the presence of water and cure.

  The compounding quantity of polycarboxylic acid is 5 to 45 weight% in a 2nd component. If it is less than 5% by weight, the acid-base reaction as a dental glass ionomer cement becomes very slow, and an operation time suitable for clinical operation cannot be obtained. If it exceeds 45% by weight, the liquid and / or cement kneaded product Since the viscosity becomes too high, the kneading operation of the first component and the second component becomes difficult.

  The reaction in which the second component of the dental glass ionomer cement is mixed with the fluoroaluminosilicate glass powder that is the main component of the first component of the dental glass ionomer cement and cured is a neutralization reaction. Since the neutralization reaction between the fluoroaluminosilicate glass powder and the polycarboxylic acid proceeds in the presence of water, water is an essential component for the cement hardening reaction.

  For the purpose of making a paste, it is possible to add water and a viscosity modifier to the first component, and the viscosity modifier can be either inorganic or organic. For example, inorganic viscosity modifiers include silica fine powder and alumina fine powder, and organic viscosity modifiers include carboxymethylcellulose calcium, sodium carboxymethylcellulose, starch, sodium starch glycolate, starch phosphate sodium, methylcellulose. , Sodium polyacrylate, alginic acid, sodium alginate, propylene glycol alginate, casein, sodium caseinate, polyethylene glycol, ethyl cellulose, hydroxyethyl cellulose, gluten, locust bean gum, gelatin and the like. Among them, even a small amount of silica fine powder and sodium carboxymethyl cellulose is preferable because of its high thickening effect and low cost. Of course, these viscosity modifiers may be used in combination of two or more. The viscosity modifier is preferably used in the first component in the range of 1 wt% to 10 wt%. If it is less than 1% by weight, the pasted first component is liable to be separated, and if it exceeds 10% by weight, kneading of the composition becomes difficult.

  Further, the second component of the dental glass ionomer cement according to the present invention can be blended with other non-reactive fillers, colorants, stabilizers and the like as long as the operability is not affected.

EXAMPLES Hereinafter, although this invention is demonstrated concretely using an Example, this invention is not limited to a following example.
The first component and the second component are prepared according to the formulation (% by weight) shown in Tables 2 to 5, mixed and mixed at the mixing ratio shown in the table, and after 1 day and 7 days from the start of kneading of the cement hardened body. The compressive strength of was measured. Similarly, solubility and storage stability were confirmed.

"Preparation of fluoroaluminosilicate glass powder"
Table 1 shows the composition of the fluoroaluminosilicate glass powders I, II and III.

<Table 1>

  Regarding the fluoroaluminosilicate glass powders I and III, the raw materials were sufficiently mixed and held in a high-temperature electric furnace at 1200 ° C. for 5 hours to melt the glass. After melting, the mixture was cooled, pulverized for 10 hours using a ball mill, and the powder after passing through a 200 mesh (ASTM) sieve was used as a fluoroaluminosilicate glass powder. With respect to the fluoroaluminosilicate glass powder II, the same operation as that of the fluoroaluminosilicate glass powders I and III was performed except that it was melted at 1100 ° C.

"Preparation of cement powder and liquid"
Tables 2 to 5 show the blends of cement used in each example and comparison.

<Table 2>

<Table 3>

<Table 4>

<Table 5>

The abbreviations in the table are as follows.
CPP-ACP: Case Infophosphopeptide-Amorphous Calcium Phosphate Fuse Rex: High-purity fused silica glass filler (manufactured by Tatsumori)

"Compressive strength test"
The measurement was performed according to ISO 9917-1: 2007 8.3 Compressive strength, and the measurement timing was 1 day and 7 days after the start of kneading. In addition, the sample was immersed and stored in 37 degreeC distilled water from the sample preparation to the measurement after seven days.

"Preservation test"
The produced test body was stored at 23 ° C., and the appearance was visually confirmed 7 days after the production.

"Solubility test"
Performed according to ISO 9917-1: 2007 8.4 Acid erosion.

  As is apparent from Tables 2 to 5, the compressive strength of the hardened cement product is reduced to a strength suitable for temporary sealing and temporary attachment by addition of a non-glassy calcium compound that reacts with polycarboxylic acid in the presence of water, and It was confirmed that the hardened cement body was not significantly dissolved.

Claims (3)

First component 1) Fluoroaluminosilicate glass powder 2) Powder of non-glass calcium compound that reacts with polycarboxylic acid in the presence of water Second component 1) Polycarboxylic acid 2) Water Dental glass ionomer cement. The dental glass ionomer cement according to claim 1, further comprising water and a viscosity modifier in the first component. Non-glass calcium compounds are calcium acetate, calcium borate, calcium carbide, calcium carbonate, calcium chloride, calcium citrate, calcium dihydrogen phosphate, calcium hydrogen phosphate, tricalcium phosphate, calcium fluoride, calcium hydroxide, Calcium hypophosphite, calcium iodide, calcium oxalate, calcium oxide, calcium sulfate, calcium sulfide, tricalcium silicate, dicalcium silicate, calcium aluminate, calcium aluminoferrite, calcium tartrate, calcium adipate, calcium laurate, calcium stearate , 12-hydroxycalcium stearate, calcium palmitate, calcium lactate, calcium montanate, calcium behenate, calcium benzoate, telef The dental use according to claim 1 or 2, which is one or more kinds selected from calcium phosphate, calcium gluconate, caseinfophosphopeptide-amorphous calcium phosphate, caseinfophosphopeptide-amorphous calcium fluoride phosphate. Glass ionomer cement.