JP2012506389A5 - - Google Patents

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Publication number
JP2012506389A5
JP2012506389A5 JP2011532512A JP2011532512A JP2012506389A5 JP 2012506389 A5 JP2012506389 A5 JP 2012506389A5 JP 2011532512 A JP2011532512 A JP 2011532512A JP 2011532512 A JP2011532512 A JP 2011532512A JP 2012506389 A5 JP2012506389 A5 JP 2012506389A5
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Japan
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het
conh
hal
atoms
mono
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JP2011532512A
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English (en)
Japanese (ja)
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JP5662325B2 (ja
JP2012506389A (ja
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Priority claimed from DE102008052943A external-priority patent/DE102008052943A1/de
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Publication of JP2012506389A5 publication Critical patent/JP2012506389A5/ja
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Publication of JP5662325B2 publication Critical patent/JP5662325B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2011532512A 2008-10-23 2009-09-24 アザインドール誘導体 Expired - Fee Related JP5662325B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008052943A DE102008052943A1 (de) 2008-10-23 2008-10-23 Azaindolderivate
DE102008052943.5 2008-10-23
PCT/EP2009/006911 WO2010046013A1 (de) 2008-10-23 2009-09-24 Azaindolderivate

Publications (3)

Publication Number Publication Date
JP2012506389A JP2012506389A (ja) 2012-03-15
JP2012506389A5 true JP2012506389A5 (en:Method) 2012-11-08
JP5662325B2 JP5662325B2 (ja) 2015-01-28

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ID=41268294

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011532512A Expired - Fee Related JP5662325B2 (ja) 2008-10-23 2009-09-24 アザインドール誘導体

Country Status (9)

Country Link
US (1) US20110207732A1 (en:Method)
EP (1) EP2342202B1 (en:Method)
JP (1) JP5662325B2 (en:Method)
AU (1) AU2009306795B2 (en:Method)
CA (1) CA2741428C (en:Method)
DE (1) DE102008052943A1 (en:Method)
ES (1) ES2559427T3 (en:Method)
IL (1) IL212285A0 (en:Method)
WO (1) WO2010046013A1 (en:Method)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5596364B2 (ja) * 2009-02-19 2014-09-24 住友化学株式会社 含窒素有機化合物及びそれを用いた有機エレクトロルミネッセンス素子
WO2011075613A1 (en) * 2009-12-18 2011-06-23 Sanofi Azaindole derivatives, their preparation and their therapeutic application
DE102010050558A1 (de) * 2010-11-05 2012-05-10 Merck Patent Gmbh 1H-Pyrrolo[2,3-b]pyridinderivate
HUE032820T2 (en) 2011-04-25 2017-11-28 Usher Iii Initiative Inc Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome
EP2718279B1 (en) * 2011-06-09 2016-08-10 Rhizen Pharmaceuticals SA Novel compounds as modulators of gpr-119
GB201217285D0 (en) * 2012-09-27 2012-11-14 Univ Central Lancashire Indole derivatives
US9227976B2 (en) 2012-10-25 2016-01-05 Usher Iii Initiative, Inc. Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome
WO2014164708A1 (en) * 2013-03-12 2014-10-09 Quanticel Pharmaceuticals, Inc. Histone dementhylase inhibitors
US9499551B2 (en) 2014-01-24 2016-11-22 Confluence Life Sciences, Inc. Substituted pyrrolo[2,3-b]pyridines for treating cancer or inflammatory diseases
MD20160118A2 (ro) 2014-05-15 2017-04-30 Iteos Therapeutics Derivaţi ai pirolidin-2,5-dionei, compoziţii farmaceutice şi metode de utilizare ca inhibitori ai IDO1
TW201630907A (zh) 2014-12-22 2016-09-01 必治妥美雅史谷比公司 ＴＧＦβＲ拮抗劑
AU2016209046A1 (en) 2015-01-23 2017-07-20 Aclaris Therapeutics, Inc. Heterocyclic ITK inhibitors for treating inflammation and cancer
BR112017019699A2 (pt) 2015-03-17 2018-09-04 Pfizer Inc. derivados substituídos por 3-indol, composições farmacêuticas e métodos para uso
US10544095B2 (en) 2015-08-10 2020-01-28 Pfizer Inc. 3-indol substituted derivatives, pharmaceutical compositions and methods for use
JP2019512474A (ja) * 2016-03-01 2019-05-16 ノバルティス アーゲー シアノ置換インドール化合物およびｌｓｄ１阻害剤としてのその使用
JP7030066B2 (ja) * 2016-05-26 2022-03-04 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー Ｅｇｆｒ阻害剤化合物
CN110582488A (zh) * 2016-09-30 2019-12-17 诺华股份有限公司 具有增强功效的免疫效应细胞疗法
WO2018210658A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2018210660A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2018210659A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2018210661A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2019057660A1 (en) 2017-09-25 2019-03-28 Basf Se INDOLE AND AZAINDOLE COMPOUNDS HAVING 6-CHANNEL SUBSTITUTED ARYL AND HETEROARYL CYCLES AS AGROCHEMICAL FUNGICIDES
EP3730489A1 (en) 2019-04-25 2020-10-28 Basf Se Heteroaryl compounds as agrochemical fungicides
EP4178580B1 (en) 2020-07-09 2025-11-05 Usher III Initiative, Inc. Bf 844 for use in the treatment of cancer
KR102513463B1 (ko) * 2020-11-26 2023-03-29 주식회사 에스앤케이테라퓨틱스 엔도솜 톨-유사 수용체를 제어하는 신규 소분자 화합물 및 이를 이용한 자가면역질환 치료제
CN116332940B (zh) * 2023-02-14 2024-09-13 广西民族大学 一种7-脱氮嘌呤衍生物及其制备方法和应用
CN121263414A (zh) * 2023-05-26 2026-01-02 上海艾力斯医药科技股份有限公司 杂芳环类化合物、其药物组合物及其应用

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7004A (en) * 1850-01-08 Connecting ctjttees to shafts of boeing instetjments
US3022A (en) * 1843-03-30 Machine for bending stibrups for paddle-wheels of steam and other
US3009A (en) * 1843-03-21 Lard-lamp
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
CN1125817C (zh) 1996-02-13 2003-10-29 曾尼卡有限公司 作为vegf抑制剂的喹唑啉衍生物
JP4464466B2 (ja) 1996-03-05 2010-05-19 アストラゼネカ・ユーケイ・リミテッド ４―アニリノキナゾリン誘導体
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
DK0948495T3 (da) * 1996-11-19 2004-06-01 Amgen Inc Aryl- og heteroarylsubstitueret, kondenseret pyrrol som antiinflammatoriske midler
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
KR100378937B1 (ko) 1997-10-20 2003-05-09 에프. 호프만-라 로슈 아게 바이사이클릭 키나아제 억제제
US6187777B1 (en) * 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
DE19951360A1 (de) * 1999-10-26 2001-05-03 Aventis Pharma Gmbh Substituierte Indole
JP2001122855A (ja) * 1999-10-27 2001-05-08 Japan Tobacco Inc インドール化合物及びその医薬用途
CA2406979A1 (en) 2000-05-31 2001-12-06 Astrazeneca Ab Indole derivatives with vascular damaging activity
JP2004502766A (ja) 2000-07-07 2004-01-29 アンギオジェン・ファーマシューティカルズ・リミテッド 血管損傷剤としてのコルヒノール誘導体
CA2410562A1 (en) 2000-07-07 2002-01-31 Angiogene Pharmaceuticals Limited Colchinol derivatives as angiogenesis inhibitors
AUPR283801A0 (en) * 2001-02-01 2001-03-01 Australian National University, The Chemical compounds and methods
SE0202463D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab Novel compounds
JP2006505552A (ja) 2002-10-09 2006-02-16 サイオス インク． ｐ３８キナーゼ阻害剤としてのアザインドール系誘導体
US7432375B2 (en) 2003-03-06 2008-10-07 Eisai R & D Management Co., Ltd. JNK inhibitors
PT1696920E (pt) 2003-12-19 2015-01-14 Plexxikon Inc Compostos e métodos para o desenvolvimento de moduladores de ret
GB0405055D0 (en) 2004-03-05 2004-04-07 Eisai London Res Lab Ltd JNK inhibitors
EP2332940B1 (en) * 2004-03-30 2012-10-31 Vertex Pharmaceuticals Incorporated Azaindoles useful as inhibitors of JAK and other protein kinases
CA2572058A1 (en) 2004-06-30 2006-01-12 Vertex Pharmaceuticals Incorporated Azaindoles useful as inhibitors of protein kinases
EP1797054A2 (en) 2004-08-02 2007-06-20 OSI Pharmaceuticals, Inc. Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds
WO2006112828A1 (en) 2005-04-15 2006-10-26 Scios, Inc. Azaindole derivatives as inhibitors of p38 kinase
FR2884821B1 (fr) 2005-04-26 2007-07-06 Aventis Pharma Sa Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation
ATE540948T1 (de) 2005-05-20 2012-01-15 Vertex Pharma Pyrrolopyridine als proteinkinasehemmer
WO2007002325A1 (en) 2005-06-22 2007-01-04 Plexxikon, Inc. Pyrrolo[2,3-b] pyridine derivatives as protein kinase inhibitors
WO2007007919A2 (en) 2005-07-14 2007-01-18 Astellas Pharma Inc. Heterocyclic janus kinase 3 inhibitors
EP2251341A1 (en) 2005-07-14 2010-11-17 Astellas Pharma Inc. Heterocyclic Janus kinase 3 inhibitors
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
US20070129364A1 (en) 2005-12-07 2007-06-07 Han-Qing Dong Pyrrolopyridine kinase inhibiting compounds
EP1962851A2 (en) 2005-12-22 2008-09-03 SmithKline Beecham Corporation Compounds
BRPI0620341A2 (pt) 2005-12-23 2011-11-08 Smithkline Beecham Corparation azaindóis inibidores de cinases aurora
JP2009537621A (ja) 2006-05-22 2009-10-29 アストラゼネカ アクチボラグ インドール誘導体
WO2008014249A2 (en) 2006-07-24 2008-01-31 Sanofi-Aventis Improved preparations of 2 -substituted pyrrolo [2, 3-b] pyrazine ( 4, 7 -diazaindole ) compounds
GB0708141D0 (en) * 2007-04-26 2007-06-06 Syngenta Participations Ag Improvements in or relating to organic compounds

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