JP2010116344A - Oral medicine containing pith fiber of tree and plant and having function of removing intestinal waste and food - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To develop an inexpensive technique of manufacturing tasty dietary fibers and functional foods using the same in a simple manufacturing process. <P>SOLUTION: The use of only pith fibers of trees and plants such as sugarcane undergone heat treatment solves the above problem. Such fibers improve constipation and when added to foods, water retention and a binding effect can further be brought about. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to an orally-administered agent and a food product having a function of removing intestinal waste products, which contain plant seed fibers, and relates to the development of a delicious, simple manufacturing process and low cost.

  The concept of dietary fiber has changed significantly in recent years, but primarily, non-digestibility in the small intestine is a physiological feature. Therefore, in addition to non-starch polysaccharides, other non-digestible carbohydrates such as non-digestible starch and non-digestible oligosaccharides are also included. In recent decades, research activities have revealed important physiological functions of improving colon function, lowering blood cholesterol levels, and suppressing postprandial blood glucose levels and insulin (Patent Document 1, Patent Document 2, Patents). Reference 3).

  Dietary fiber is recognized as having an intestinal regulating effect, and it is recommended to eat a lot. However, it is extremely difficult to eat 5 to 10 g a day because of the tasteless taste. Have difficulty. As a result, many people (especially women) with constipation due to a lack of dietary fiber depend on drugs or enemas, but there were problems such as abdominal pain and habituation.

  The source of dietary fiber is plant foods such as cereals, beans, fruits, seeds, etc., specifically wheat, rice, corn, etc., and also includes barley, rye, millet, sorghum and the like.

  Commonly used as dietary fiber in the market is crystalline cellulose (Avicel (Asahi Kasei Chemical), Vitacel (Germany, Neutrinova)) and wood and non-wood pulp. It is mainly manufactured by dissolving it in a solvent and recrystallizing it. Recently, many foods are blended by pulverizing bran, okara, etc., but they are crisp and not delicious. There are also many attempts to use bagasse, a sugarcane pomace, as a dietary fiber. However, since there are a lot of silica and lignin, after blasting, it is fermented with koji mold with high xylase activity and then commercialized, but it has the disadvantages of high cost and bitter taste.

Japanese Patent Laid-Open No. 2007-48 JP 2004-65018 A JP 2007-174974 A

  An object of the present invention is to develop a method that is delicious, has a simple manufacturing process, and is low in cost when manufacturing dietary fiber and a functional food using the same.

  As a result of diligent efforts to solve the above-mentioned problems, the present inventors have found that the above-mentioned problems can be solved by heat-treating and using only plant fibers such as sugar millet.

That is, the present invention
(1) An orally administered agent having a function of removing intestinal waste products, characterized by containing dietary fiber derived from heat-treated plant nuts;
(2) A functional food having a function of removing intestinal waste products, characterized by containing dietary fiber derived from heat-treated plant nuts;
(3) The orally administered preparation according to (1) or the functional food according to (2), wherein the plant is sugar millet,
(4) A method for producing an orally administered agent or food having a function of removing intestinal waste products, characterized by adding the heat-treated material after separating the fruit of the plant
It is.

As the vegetation in the present invention, sugar millet is representative, but even if it is cuolian, asparagus, sunflower or cocoon, its solid fiber can be taken out and used in the present invention.
Sugar millet has stems that are wooded like bamboo and have knots, and the center of the stem between knots is not a hollow but a marrow and contains sugar. There are various uses such as eating the bone marrow of the stem raw material, and using the squeezed juice as a raw material for sugar production and other food chemical industries and industrial ethyl alcohol production.

  Sugar millet consists of a skin called lined and a solid fiber called piss. Lined is rich in silica and lignin, while pis is rich in hemicellulose and has a sponge structure (FIG. 1). Sugar cane consists of 16% sugar, 7% outer skin, 7% solid fiber, 0.016% epidermal lipid (WAX) and 70% moisture.

  In order to take out the solid fibers from the sugar millet, the lined portion of the epidermis and the Pith of the internal tissue are separated by a separation device such as a Kane separation system (AmClyde, USA, US Pat. No. 3,690,358, FIG. 2) Pressure is applied to the pissed portion by a pressing device to reduce the water content, and hydrothermal treatment is performed with hot steam at 100 to 200 ° C. This treatment not only softens the strong fiber structure, but also improves the texture, shortens the drying time, and improves the grinding efficiency. Thereafter, it is dried by heating with hot air, infrared rays, microwaves, and the like, and after drying, it is molded using a pelletizer or the like. Pelletization stabilizes the supply to the next pulverization step, can increase the efficiency of the pulverizer, and drying proceeds as the temperature rises during molding. Then, it is pulverized by a pulverizer such as an impact pulverizer.

  The solid fiber extracted from sugarcane has a high sugar content and starts to rot in about half a day, so it was only used for feed. The present inventors have found that it is effective to heat the solid fibers as a technique for improving this point. It was also confirmed by experiments that the heat treatment temperature is preferably 140 ° C. to 160 ° C.

  If the dietary fiber obtained in this way is taken by a person with constipation as an oral administration agent, it exhibits a bowel movement effect, and if used as a food, in addition to the bowel movement effect, water retention, tethering effect, shelf life effect Various effects can be obtained. For example, the results show that when placed in bread, it is fragrant, with cookies it feels moist, and with udon it lasts longer. In addition, it can be added to Bolo, ice cream and the like.

  Although the dietary fiber derived from the plant seeds of the present invention is water-insoluble, the effect of fermentation by enterobacteria is slow, it reaches the lower rectum, and can exert the function of regulating the intestines. . On the other hand, water-soluble dietary fibers such as pectin and β-glucan are difficult to reach the rectum because of the rapid influence of fermentation, and it is difficult to achieve an intestinal function.

  In particular, sugar millet solid fibers have a variety of crystal structures (Fig. 3) and fiber lengths are different. Long fiber lengths reach the rectum, while short fiber lengths stay in the mid-abdomen. It is possible to remove intestinal waste in the entire intestine, and exerts an effect that dietary fibers such as crystalline cellulose do not have.

  According to the present invention, dietary fiber obtained from sugarcane solid fiber can be contained up to about 60% of food. Conventional dietary fiber is limited to about 3% at the maximum from the point of taste, and in contrast, the present invention can contain a significant amount of dietary fiber, so it has a dramatic effect on improving constipation and the like. It can be demonstrated.

  According to the present invention, not only constipation can be improved, but also by adding to foods, water retention can be initially achieved.

  In order to explain the present invention concretely, examples are shown below, but the present invention is not limited to these examples.

(Manufacturing method of dietary fiber)
1. Sugarcane stems that had been defoliated and cut to a length of 10 cm to 30 cm were supplied to a cane separator (Mitsubishi Paper Co., Ltd., FIG. 4). For defoliation and stem cutting, those used in the sugar industry were used.

  2. The sugarcane stalk supplied to the separator was split in half, and the internal tissue was scraped off by a rotary blade.

  3. The scraped internal structure was sent to a screw press by a screw conveyor, and sugar juice was squeezed.

  4). The squeezed sugar juice can be made into sugar by a usual method. The internal structure in which the sugar juice is squeezed has a moisture content of 30% to 50%.

  5. An internal structure having a water content of 30% to 50% was supplied to the steamer to eliminate air in the system after sealing. While introducing steam from 0.7 MPa to 1.0 MPa, hot water treatment with condensed steam was performed. The treatment time was adjusted to 30 to 120 minutes in consideration of hue and taste.

  6). After depressurization and cooling, the hydrothermally treated internal structure was taken out, and the moisture content was reduced to around 20% by sun drying and heat drying with a dryer.

  7). The dried internal structure was pelletized with a letterer to make it easy to store and grind.

  8). The pellets were supplied to a pulverizer and pulverized to obtain dietary fiber powder having an average particle size of 30 to 100 μm.

  9. The pelletized internal structure was further dried by sun drying and heat drying with a drier so that the water content was 10% or less.

  10. The dried pellets were traced over time with changes in the number of viable bacteria and confirmed the storage stability. As a result, it was found that the dried pellets were stable for more than 1 year at 6% water content.

(Manufacture of Bolo containing sugar millet solid fiber)
The comparative experiment of the conventional product and the product of the present invention was conducted according to the blending ratio shown in Table 1 below.

When a prototype of Bolo was made based on the blending ratio in Table 1 above, the result was as shown in FIG.
That is, Bolo of the conventional example which mix | blended 2.6% of crystalline cellulose did not become a rod shape which has a bad connection effect and can pass a machine, and added egg etc. as a connection material additionally. However, it was not a stepped state that could be applied to the machine, and it was rugged, so I created Bolo manually. Therefore, it was not round, and it was not a uniform shape, but a shape that was difficult to become a product.

  On the other hand, the sugar milled solid fiber of the present invention was added little by little into the kneader, but the effect of joining was high, and even when 10% was added, it could be formed into a rod shape and passed through the machine. Therefore, it was possible to maintain a spherical and uniform shape as shown in the photograph of FIG.

(Production and use results of oral dosage forms)
In Example 2, it was possible to add up to 10% of sugar millet solid fiber, and in order to effectively improve constipation, when it was tested to what extent it could be added, it was found that it could be up to 60%. It was.

That is,
Sugar millet inner fiber 60.0%
Sugar content 80% syrup 30.5
Corn starch 7.0
Sugar millet wax 2.5
When an orally administered preparation was prepared with the formulation, a uniform pill could be obtained as shown in FIG.

  The prepared pills were pulverized and added to Bolo at a rate of 50%, and the subjects were allowed to take the test to verify the effect of improving bowel movements. A questionnaire result that 35 out of 40 monitors were effective in bowel bowel movement was obtained. The effect examples (impressions) are as follows.

Efficacy example 1 62 year old male
I took a lot of different drugs and had trouble with the stool, but when I took 2 tablets of the product of the present invention, I got a connected stool.

Efficacy example 2 60-year-old male, female in their 40s, female in their 60s.

Efficacy Example 3 Women in their 30s and Women in their 40s Severe constipation for 1 week was not effective with 2 tablets, but 5 tablets were taken the next day and the stool was pleasant.

Efficacy example 4 Male in his 80s Always taking constipation on an overseas trip made taking 4 tablets a pleasant stool.

Efficacy Example 5 Female in her 50s Severe constipation, but when other oral constipation-improving agents were stopped and the oral preparation of the present invention was taken, it was a natural fiber and no abdominal pain.

(Comparison experiment with Bolo)
Number of female college students 14 (volunteers)
Method Group A: Subject group Plain Bolo 7
Group B: Test group Polo (sugar milled solid fiber) 10% added Bolo 7 people Period 1 week, 100 g / day
Group A and Group B were changed after 1 day, and the dose was 50 g / day for 1 week. Results The test group had a bowel movement (1.1 times to 1.9 times) and the amount of defecation (2.5 times) compared to the control group. There is a tendency to increase the number of stool (→ 3.5), and the difference in daily stool volume between week 1 and week 2 is significantly higher when eating Bolo from the test group. Millet piss was found to be effective in increasing the amount of defecation.

As a result of the meal survey, the daily dietary fiber intake from foods other than Bolo was 12.3 g on average.
* Piss component: dietary fiber 79.6% (main component: cellulose 37%, hemicellulose 32%, lignin 10.6%)

(Manufacture of cookies)
Two types of cookies were produced by changing the content of cookies containing sugarcane solid fibers and compared.
Example 1 Example 2
Sugar millet fiber 8% Sugar mill fiber 15.8%
Wheat flour 49.5% Wheat flour 49.5%
Palm oil 25% Palm oil 25%
Reduced maltose starch syrup 16% Reduced maltose starch syrup 8.2%
Other 1.5% Other 1.5%

  As a result of a comparative examination of the above blending, the cookie blended with 15.8% sugar millet solid fiber was not suitable for commercialization in terms of taste. However, 8% sugar millet fiber was able to produce delicious cookies. The results are shown in FIG.

On the other hand, although the crystalline cellulose was also tested, it was impossible to add 1% or more.
Moreover, although it can be technically contained about 5-8% in bran, okara, etc., it has no taste and cannot be commercialized as a cookie.

The figure which shows the cross section of sugar millet. The figure which shows the cane separation system (made in the United States). The figure which shows the crystal structure of sugar millet. The figure which shows the cane separator apparatus (made by Mitsubishi Paper Industries). The figure which shows the comparison with the Bolo (right) containing this invention product, and the Bolo (left) containing crystalline cellulose. The figure which shows the oral administration agent containing 50% of sugar millet solid fiber. The figure which shows a cookie with a sugar millet inside solid fiber (left 8%, right 15.8%).

Claims (4)

  An orally administered agent having a function of removing intestinal waste products, comprising a dietary fiber derived from heat-treated plant nuts.   A functional food having a function of removing intestinal waste products, comprising a dietary fiber derived from heat-treated plant nuts.   The orally-administered agent according to claim 1 or the functional food according to claim 2, wherein the plant is sugar millet.   A method for producing an orally administered agent or food having a function of removing intestinal waste products, characterized by adding the heat-treated material after separating the berries of plants.

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