JP2009513643A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009513643A5 JP2009513643A5 JP2008537869A JP2008537869A JP2009513643A5 JP 2009513643 A5 JP2009513643 A5 JP 2009513643A5 JP 2008537869 A JP2008537869 A JP 2008537869A JP 2008537869 A JP2008537869 A JP 2008537869A JP 2009513643 A5 JP2009513643 A5 JP 2009513643A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- albumin
- dye
- peg
- indicator reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 27
- 239000000975 dye Substances 0.000 claims 20
- 102000009027 Albumins Human genes 0.000 claims 18
- 108010088751 Albumins Proteins 0.000 claims 18
- 238000000034 method Methods 0.000 claims 14
- 239000003153 chemical reaction reagent Substances 0.000 claims 12
- 230000005284 excitation Effects 0.000 claims 6
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical group O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 claims 6
- 230000007717 exclusion Effects 0.000 claims 5
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 239000000047 product Substances 0.000 claims 4
- MOFVSTNWEDAEEK-UHFFFAOYSA-M indocyanine green Chemical compound [Na+].[O-]S(=O)(=O)CCCCN1C2=CC=C3C=CC=CC3=C2C(C)(C)C1=CC=CC=CC=CC1=[N+](CCCCS([O-])(=O)=O)C2=CC=C(C=CC=C3)C3=C2C1(C)C MOFVSTNWEDAEEK-UHFFFAOYSA-M 0.000 claims 3
- 229960004657 indocyanine green Drugs 0.000 claims 3
- PEEHTFAAVSWFBL-UHFFFAOYSA-N Maleimide Chemical compound O=C1NC(=O)C=C1 PEEHTFAAVSWFBL-UHFFFAOYSA-N 0.000 claims 2
- 208000034486 Multi-organ failure Diseases 0.000 claims 2
- 208000010718 Multiple Organ Failure Diseases 0.000 claims 2
- 239000000084 colloidal system Substances 0.000 claims 2
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 claims 2
- 208000029744 multiple organ dysfunction syndrome Diseases 0.000 claims 2
- UATCLPJEZJKNHE-UHFFFAOYSA-N n-(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-yl)-2-iodoacetamide Chemical compound O1C(=O)C2=CC(NC(=O)CI)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 UATCLPJEZJKNHE-UHFFFAOYSA-N 0.000 claims 2
- 150000003573 thiols Chemical group 0.000 claims 2
- 101710150350 Albumin-2 Proteins 0.000 claims 1
- 239000006227 byproduct Substances 0.000 claims 1
- 125000002228 disulfide group Chemical group 0.000 claims 1
- 230000009977 dual effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000049 pigment Substances 0.000 claims 1
- 230000003068 static effect Effects 0.000 claims 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/258,646 US7345150B2 (en) | 2002-03-26 | 2005-10-25 | Albumin-based colloid composition having at least one protected thiol region, methods of making, and methods of use |
| PCT/US2006/041432 WO2007050581A2 (en) | 2005-10-25 | 2006-10-24 | An albumin-based colloid composition having at least one protected thiol region, methods of making, and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009513643A JP2009513643A (ja) | 2009-04-02 |
| JP2009513643A5 true JP2009513643A5 (https=) | 2009-12-17 |
Family
ID=37968466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008537869A Pending JP2009513643A (ja) | 2005-10-25 | 2006-10-24 | 少なくとも１つの保護されたチオール領域を有するアルブミンベースコロイド組成物、その製造方法および使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7345150B2 (https=) |
| EP (1) | EP1940474A4 (https=) |
| JP (1) | JP2009513643A (https=) |
| CA (1) | CA2627155A1 (https=) |
| WO (1) | WO2007050581A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7345150B2 (en) * | 2002-03-26 | 2008-03-18 | Medical University Of Toledo | Albumin-based colloid composition having at least one protected thiol region, methods of making, and methods of use |
| US8036489B2 (en) * | 2005-07-07 | 2011-10-11 | Shutterfly, Inc. | Systems and methods for creating photobooks |
| US9624259B2 (en) * | 2007-04-16 | 2017-04-18 | Regentis Biomaterials Ltd. | Compositions and methods for scaffold formation |
| CL2008002399A1 (es) | 2007-08-16 | 2009-01-02 | Pharmaessentia Corp | Conjugado sustancialmente puro que posee una porcion polimerica, una porcion proteica (interferon alfa 2b) y un ligante alifatico de 1 a 10 atomos de carbono, util en el tratamiento de las hepatitis b o c. |
| US20120010144A1 (en) * | 2009-04-03 | 2012-01-12 | Ragheb Assaly | Peg-albumin composition having at least one protected thiol region as a platform for medications |
| EP3808378A1 (en) * | 2011-05-27 | 2021-04-21 | Baxalta GmbH | Therapeutic proteins with increased half-life and methods of preparing same |
| US11559567B2 (en) | 2014-11-06 | 2023-01-24 | Pharmaessentia Corporation | Dosage regimen for pegylated interferon |
| JP2018501814A (ja) | 2014-11-11 | 2018-01-25 | クララ フーズ カンパニー | 卵白タンパク質産生のための方法および組成物 |
| US12096784B2 (en) | 2019-07-11 | 2024-09-24 | Clara Foods Co. | Protein compositions and consumable products thereof |
| BR112022000545A2 (pt) | 2019-07-11 | 2022-04-05 | Clara Foods Co | Composições de proteína e produtos de consumo destas |
| US10927360B1 (en) | 2019-08-07 | 2021-02-23 | Clara Foods Co. | Compositions comprising digestive enzymes |
| RU2753589C1 (ru) * | 2020-12-08 | 2021-08-18 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний" (НИИ КПССЗ) | Способ прогнозирования полиорганной недостаточности после операций на сердце, выполненных в условиях искусственного кровообращения |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2727027A (en) * | 1955-12-13 | Process for preparing oxyalkylated | ||
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| IL47468A (en) * | 1975-06-12 | 1979-05-31 | Rehovot Res Prod | Process for the cross-linking of proteins using water soluble cross-linking agents |
| US5077222A (en) * | 1988-09-30 | 1991-12-31 | Miles Inc. | Method for assaying for proteins using a dual indicator reagent composition |
| US5324844A (en) * | 1989-04-19 | 1994-06-28 | Enzon, Inc. | Active carbonates of polyalkylene oxides for modification of polypeptides |
| ATA194989A (de) * | 1989-08-17 | 1990-04-15 | Koller Ernst | Verfahren zum nachweis und zur bestimmung von humanserumalbumin in biologischen fluessigkeiten mit hilfe fluorogener cyanin-farbstoffe |
| US6063764A (en) * | 1992-06-01 | 2000-05-16 | Washington University & Chiron Corp. | Method for using lipoprotein associated coagulation inhibitor to treat sepsis |
| AU682894B2 (en) * | 1993-10-28 | 1997-10-23 | Institut National De La Recherche Agronomique | Composition based on amino acids intended for the treatment of sepsis or of an attack bringing about an inflammatory reaction, in animals and man |
| ES2172573T3 (es) * | 1993-12-01 | 2002-10-01 | Bioartificial Gel Technologies Inc | Hidrogel basado en albumina. |
| US5583114A (en) * | 1994-07-27 | 1996-12-10 | Minnesota Mining And Manufacturing Company | Adhesive sealant composition |
| US5650234A (en) * | 1994-09-09 | 1997-07-22 | Surface Engineering Technologies, Division Of Innerdyne, Inc. | Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces |
| JP3310676B2 (ja) * | 1994-09-26 | 2002-08-05 | ザ・ジョーンズ・ホプキンス・ユニバーシティ | 眼における脈絡膜の血流および迷入血管構造の改善された視覚化 |
| US5704358A (en) * | 1994-11-22 | 1998-01-06 | The Trustees Of Columbia University In The City Of New York | Method and apparatus for diagnosing capillary leak |
| US5714511A (en) * | 1995-07-31 | 1998-02-03 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Selective prevention of organ injury in sepsis and shock using selection release of nitric oxide in vulnerable organs |
| US5952009A (en) * | 1996-03-20 | 1999-09-14 | New York Blood Center | Methods for preventing the transmission of or treating patients infected with herpesvirus |
| WO1998009647A2 (en) * | 1996-09-06 | 1998-03-12 | Medarex, Inc. | Cyanidin compositions and therapeutic and diagnostic uses therefor |
| US6129912A (en) * | 1997-09-26 | 2000-10-10 | Uab Research Foundation | Polyethylene glycol-protein compositions which reduce the antigenic display of red blood cells |
| WO2000023101A1 (en) * | 1998-10-22 | 2000-04-27 | Eli Lilly And Company | Methods for treating sepsis |
| US7037895B2 (en) * | 2001-03-27 | 2006-05-02 | Medical College Of Ohio | Albumin-based colloid composition and method of use in treating hypovolemia and multiorgan dysfunction |
| US7345150B2 (en) * | 2002-03-26 | 2008-03-18 | Medical University Of Toledo | Albumin-based colloid composition having at least one protected thiol region, methods of making, and methods of use |
| US7884068B2 (en) | 2002-03-26 | 2011-02-08 | Assaly Ragheb A | Albumin-based colloid composition having at least one protected thiol region, methods of making, and methods of use |
-
2005
- 2005-10-25 US US11/258,646 patent/US7345150B2/en not_active Expired - Lifetime
-
2006
- 2006-10-24 EP EP06826542A patent/EP1940474A4/en not_active Withdrawn
- 2006-10-24 WO PCT/US2006/041432 patent/WO2007050581A2/en not_active Ceased
- 2006-10-24 CA CA002627155A patent/CA2627155A1/en not_active Abandoned
- 2006-10-24 JP JP2008537869A patent/JP2009513643A/ja active Pending
-
2008
- 2008-01-22 US US12/009,580 patent/US20080247958A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009513643A5 (https=) | ||
| Xiao et al. | Versatile fluorescent probes for imaging the superoxide anion in living cells and in vivo | |
| Li et al. | An efficient 1064 nm NIR‐II excitation fluorescent molecular dye for deep‐tissue high‐resolution dynamic bioimaging | |
| Yin et al. | Targeted cancer imaging and photothermal therapy via monosaccharide-imprinted gold nanorods | |
| Whittington et al. | Suppression of red blood cell autofluorescence for immunocytochemistry on fixed embryonic mouse tissue | |
| Huxley et al. | Role of a glycocalyx on coronary arteriole permeability to proteins: evidence from enzyme treatments | |
| Rumyantsev et al. | Near-infrared bioluminescent proteins for two-color multimodal imaging | |
| Levenson et al. | Multispectral imaging in biology and medicine: slices of life | |
| Du et al. | Near-infrared-II cyanine/polymethine dyes, current state and perspective | |
| Porter et al. | Vascular patterns in the heads of dinosaurs: evidence for blood vessels, sites of thermal exchange, and their role in physiological thermoregulatory strategies | |
| Yang et al. | FRET ratiometric nanoprobes for nanoparticle monitoring | |
| EP1181940A3 (de) | Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung | |
| Cardoso Dos Santos et al. | Time‐gated FRET nanoprobes for autofluorescence‐free long‐term in vivo imaging of developing zebrafish | |
| Yan et al. | Fluorescent chemosensors for ion and molecule recognition: The next chapter | |
| Dolinak et al. | Hypoglycaemia is a cause of axonal injury | |
| Samanta et al. | Biocompatible surface-enhanced Raman scattering nanotags for in vivo cancer detection | |
| Croce et al. | Autofluorescence spectroscopy for monitoring metabolism in animal cells and tissues | |
| Konno et al. | Pathological application of carbocyanine dye-based multicolour imaging of vasculature and associated structures | |
| Borvinskaya et al. | Parallel in vivo monitoring of pH in gill capillaries and muscles of fishes using microencapsulated biomarkers | |
| Zhao et al. | Glutathione-activated emission of ultrasmall gold nanoparticles in the second near-infrared window for imaging of early kidney injury | |
| Lim et al. | Shortwave infrared fluorofluorophores for multicolor in vivo imaging | |
| Xu et al. | Surface-functionalized Halo-Tag gold nanoprobes for live-cell long-term super-resolution imaging of endoplasmic reticulum dynamics | |
| Xu et al. | Diffuse optical imaging and spectroscopy for cancer | |
| Croce et al. | Integrated autofluorescence characterization of a modified‐diet liver model with accumulation of lipids and oxidative stress | |
| Ravotto et al. | Three-photon spectroscopy of porphyrins |