JP2009505740A5 - - Google Patents
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- Publication number
- JP2009505740A5 JP2009505740A5 JP2008528112A JP2008528112A JP2009505740A5 JP 2009505740 A5 JP2009505740 A5 JP 2009505740A5 JP 2008528112 A JP2008528112 A JP 2008528112A JP 2008528112 A JP2008528112 A JP 2008528112A JP 2009505740 A5 JP2009505740 A5 JP 2009505740A5
- Authority
- JP
- Japan
- Prior art keywords
- stick
- drug
- dry powder
- container
- inhaler
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 21
- 229940079593 drug Drugs 0.000 claims 20
- 239000000843 powder Substances 0.000 claims 10
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 238000007789 sealing Methods 0.000 claims 2
- 102000004877 Insulin Human genes 0.000 claims 1
- 108090001061 Insulin Proteins 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 229940112141 dry powder inhaler Drugs 0.000 claims 1
- 229940125396 insulin Drugs 0.000 claims 1
- 230000000007 visual effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71130905P | 2005-08-25 | 2005-08-25 | |
| US60/711,309 | 2005-08-25 | ||
| PCT/US2006/032925 WO2007024953A1 (en) | 2005-08-25 | 2006-08-23 | Drug containment systems with sticks, related kits, dry powder inhalers and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009505740A JP2009505740A (ja) | 2009-02-12 |
| JP2009505740A5 true JP2009505740A5 (https=) | 2009-09-03 |
| JP5108764B2 JP5108764B2 (ja) | 2012-12-26 |
Family
ID=37771938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008528112A Expired - Fee Related JP5108764B2 (ja) | 2005-08-25 | 2006-08-23 | 薬剤格納システムを備えたスティック、並びに関連するキット、乾燥粉末吸入器および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8327843B2 (https=) |
| EP (1) | EP1934805A4 (https=) |
| JP (1) | JP5108764B2 (https=) |
| CN (1) | CN101313293B (https=) |
| AU (1) | AU2006283113B2 (https=) |
| CA (1) | CA2618520C (https=) |
| WO (1) | WO2007024953A1 (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
| EP1986679B1 (en) | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| JP5385793B2 (ja) * | 2007-02-27 | 2014-01-08 | アイバックス ファーマシューティカルズ アイルランド | 計量式吸入器のキット |
| EP2042208A1 (en) * | 2007-09-25 | 2009-04-01 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device |
| JP5570996B2 (ja) | 2007-12-14 | 2014-08-13 | エアロデザインズ インコーポレイテッド | エアロゾル化可能な食料品の送達 |
| CN101827626B (zh) | 2008-06-13 | 2015-03-18 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
| TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| DK2405963T3 (da) | 2009-03-11 | 2013-12-16 | Mannkind Corp | Apparat, system og fremgangsmåde til at måle modstand i en inhalator |
| KR102584844B1 (ko) | 2009-06-12 | 2023-10-04 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
| US20130255678A1 (en) * | 2009-07-01 | 2013-10-03 | Microdose Therapeutx, Inc. | Nebulizer for infants and respiratory compromised patients |
| CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| CN102985125A (zh) | 2010-06-21 | 2013-03-20 | 曼金德公司 | 干粉药物输送系统和方法 |
| SG194034A1 (en) | 2011-04-01 | 2013-11-29 | Mannkind Corp | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| MX2014004983A (es) | 2011-10-24 | 2014-09-22 | Mannkid Corp | Metodos y composiciones para tratar dolor. |
| KR102264177B1 (ko) | 2012-07-12 | 2021-06-11 | 맨카인드 코포레이션 | 건조 분말 약물 전달 시스템 및 방법 |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| WO2014070769A1 (en) | 2012-10-29 | 2014-05-08 | The University Of North Carolina At Chapel Hill | Methods and compositions for treating mucosal tissue disorders |
| EP3587404B1 (en) | 2013-03-15 | 2022-07-13 | MannKind Corporation | Microcrystalline diketopiperazine compositions, methods for preparation and use thereof |
| MX375448B (es) | 2013-07-18 | 2025-03-06 | Mannkind Corp | Composiciones farmacéuticas en polvo seco estables al calor y métodos. |
| EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| WO2018071435A1 (en) | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
| US11077292B2 (en) | 2018-08-29 | 2021-08-03 | Star Luminal LLC | System of medical indicators having multisensory, multipurpose and multifunctional features |
| WO2020046535A1 (en) | 2018-08-29 | 2020-03-05 | Star Luminal LLC | System of medical indicators having multisensory, multipurpose and multifunctional features |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3948264A (en) * | 1975-05-21 | 1976-04-06 | Mead Johnson & Company | Inhalation device |
| ES506585A0 (es) * | 1980-10-30 | 1982-09-01 | Riker Laboratories Inc | Un dispositivo para facilitar la inhalacion oral de medica- mentos en forma de polvo |
| WO1990013327A1 (en) * | 1989-04-28 | 1990-11-15 | Riker Laboratories, Inc. | Dry powder inhalation device |
| GB2253200A (en) * | 1991-02-01 | 1992-09-02 | Harris Pharma Ltd | Inhalation apparatus and fracturable capsule for use therewith |
| US6055980A (en) * | 1991-05-20 | 2000-05-02 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| US5497763A (en) * | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
| US5533502A (en) * | 1993-05-28 | 1996-07-09 | Vortran Medical Technology, Inc. | Powder inhaler with aerosolization occurring within each individual powder receptacle |
| CA2179202C (en) * | 1993-12-18 | 2006-06-06 | Stephen William Eason | Powder inhalator |
| JP3792743B2 (ja) * | 1995-01-26 | 2006-07-05 | 株式会社リコー | トナー充填方法及び装置 |
| US5622166A (en) * | 1995-04-24 | 1997-04-22 | Dura Pharmaceuticals, Inc. | Dry powder inhaler delivery system |
| SE504458C2 (sv) * | 1995-06-21 | 1997-02-17 | Lars Gunnar Nilsson | Inhalator för elektrisk dosering av substanser |
| SE9502800D0 (sv) * | 1995-08-10 | 1995-08-10 | Astra Ab | Disposable inhaler |
| US5909829A (en) * | 1997-04-01 | 1999-06-08 | Xerox Corporation | Vibratory filler for powders |
| US5947169A (en) * | 1997-04-01 | 1999-09-07 | Xerox Corporation | Oscillating valve for powders |
| US20010007853A1 (en) * | 1998-01-08 | 2001-07-12 | Dimarchi Richard Dennis | Method for administering monomeric insulin analogs |
| US6132416A (en) * | 1998-09-01 | 2000-10-17 | Broselow; James B. | Universal medication dosing system |
| GB9909357D0 (en) | 1999-04-24 | 1999-06-16 | Glaxo Group Ltd | Medicament carrier |
| US7171965B2 (en) * | 2000-02-01 | 2007-02-06 | Valois S.A.S. | Breath actuated dry powder inhaler and tape dose strip |
| US6971383B2 (en) * | 2001-01-24 | 2005-12-06 | University Of North Carolina At Chapel Hill | Dry powder inhaler devices, multi-dose dry powder drug packages, control systems, and associated methods |
| JP4371660B2 (ja) * | 2001-04-26 | 2009-11-25 | ニユー・イングランド・フアーマシユーテイカルズ・インコーポレイテツド | 液体状および粉末状薬剤のための定量投与デバイス |
| GB0120018D0 (en) * | 2001-08-16 | 2001-10-10 | Meridica Ltd | Pack containing medicament and dispensing device |
| WO2003030974A1 (en) * | 2001-10-08 | 2003-04-17 | Eli Lilly And Company | Portable medication inhalation kit |
| GB0130055D0 (en) * | 2001-12-14 | 2002-02-06 | Technology Innovation Ltd | Medicament packaging |
| US6923175B2 (en) * | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
| GR1004350B (el) * | 2002-03-29 | 2003-09-26 | Συσκευη εισπνοων ξηρης σκονης | |
| US7677411B2 (en) * | 2002-05-10 | 2010-03-16 | Oriel Therapeutics, Inc. | Apparatus, systems and related methods for processing, dispensing and/or evaluatingl dry powders |
| US6985798B2 (en) * | 2002-05-10 | 2006-01-10 | Oriel Therapeutics, Inc. | Dry powder dose filling systems and related methods |
| US6889690B2 (en) * | 2002-05-10 | 2005-05-10 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages |
| US7118010B2 (en) * | 2002-05-10 | 2006-10-10 | Oriel Therapeutics, Inc. | Apparatus, systems and related methods for dispensing and /or evaluating dry powders |
| US6799571B1 (en) * | 2002-06-19 | 2004-10-05 | Molecular Rotation, Llc | Medicinal powder delivery system |
| US6769436B2 (en) * | 2002-06-28 | 2004-08-03 | Richard C. Horian | Volatile inhaler and method |
| US6941947B2 (en) * | 2002-12-18 | 2005-09-13 | Quadrant Technologies Limited | Unit dose dry powder inhaler |
| JP2006520727A (ja) * | 2003-03-20 | 2006-09-14 | ウィリアムズ−ハートマン,ウェイド,イー. | 子供に安全で高齢者に優しいブリスタカードパッケージ |
| US20050263153A1 (en) * | 2004-05-28 | 2005-12-01 | Quadrant Technologies Limited | Unit dose dry powder inhaler |
| US20080272022A1 (en) * | 2004-07-14 | 2008-11-06 | Gpc Biotech Ag | Variable-Dose Packaging System |
-
2006
- 2006-08-23 CN CN2006800305662A patent/CN101313293B/zh not_active Expired - Fee Related
- 2006-08-23 AU AU2006283113A patent/AU2006283113B2/en not_active Ceased
- 2006-08-23 CA CA2618520A patent/CA2618520C/en not_active Expired - Fee Related
- 2006-08-23 EP EP06789958.3A patent/EP1934805A4/en not_active Withdrawn
- 2006-08-23 JP JP2008528112A patent/JP5108764B2/ja not_active Expired - Fee Related
- 2006-08-23 US US12/064,705 patent/US8327843B2/en not_active Expired - Fee Related
- 2006-08-23 WO PCT/US2006/032925 patent/WO2007024953A1/en not_active Ceased
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