JP2008540435A5 - - Google Patents
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- JP2008540435A5 JP2008540435A5 JP2008510154A JP2008510154A JP2008540435A5 JP 2008540435 A5 JP2008540435 A5 JP 2008540435A5 JP 2008510154 A JP2008510154 A JP 2008510154A JP 2008510154 A JP2008510154 A JP 2008510154A JP 2008540435 A5 JP2008540435 A5 JP 2008540435A5
- Authority
- JP
- Japan
- Prior art keywords
- transgene
- composition
- region
- virus vector
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67721305P | 2005-05-02 | 2005-05-02 | |
| US60/677,213 | 2005-05-02 | ||
| US79021706P | 2006-04-08 | 2006-04-08 | |
| US60/790,217 | 2006-04-08 | ||
| PCT/US2006/016943 WO2006119341A2 (en) | 2005-05-02 | 2006-05-02 | Gene therapy for spinal cord disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012282826A Division JP2013082731A (ja) | 2005-05-02 | 2012-12-26 | 脊髄疾患の遺伝子療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008540435A JP2008540435A (ja) | 2008-11-20 |
| JP2008540435A5 true JP2008540435A5 (https=) | 2009-06-25 |
| JP5766389B2 JP5766389B2 (ja) | 2015-08-19 |
Family
ID=37308661
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008510154A Active JP5766389B2 (ja) | 2005-05-02 | 2006-05-02 | 脊髄疾患の遺伝子療法 |
| JP2012282826A Pending JP2013082731A (ja) | 2005-05-02 | 2012-12-26 | 脊髄疾患の遺伝子療法 |
| JP2015063153A Pending JP2015163613A (ja) | 2005-05-02 | 2015-03-25 | 脊髄疾患の遺伝子療法 |
| JP2017032174A Pending JP2017132774A (ja) | 2005-05-02 | 2017-02-23 | 脊髄疾患の遺伝子療法 |
| JP2019203155A Active JP6887008B2 (ja) | 2005-05-02 | 2019-11-08 | 脊髄疾患の遺伝子療法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012282826A Pending JP2013082731A (ja) | 2005-05-02 | 2012-12-26 | 脊髄疾患の遺伝子療法 |
| JP2015063153A Pending JP2015163613A (ja) | 2005-05-02 | 2015-03-25 | 脊髄疾患の遺伝子療法 |
| JP2017032174A Pending JP2017132774A (ja) | 2005-05-02 | 2017-02-23 | 脊髄疾患の遺伝子療法 |
| JP2019203155A Active JP6887008B2 (ja) | 2005-05-02 | 2019-11-08 | 脊髄疾患の遺伝子療法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10744210B2 (https=) |
| EP (1) | EP1879623B1 (https=) |
| JP (5) | JP5766389B2 (https=) |
| CN (1) | CN105770909A (https=) |
| AU (1) | AU2006242129A1 (https=) |
| BR (1) | BRPI0611540A2 (https=) |
| CA (1) | CA2606490C (https=) |
| DK (1) | DK1879623T3 (https=) |
| ES (1) | ES2394482T3 (https=) |
| IL (2) | IL187023A (https=) |
| MX (1) | MX2007013734A (https=) |
| PL (1) | PL1879623T3 (https=) |
| PT (1) | PT1879623E (https=) |
| WO (1) | WO2006119341A2 (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL1879623T3 (pl) * | 2005-05-02 | 2013-03-29 | Genzyme Corp | Terapia genowa zaburzeń rdzenia kręgowego |
| EP1879624B1 (en) | 2005-05-02 | 2011-09-21 | Genzyme Corporation | Gene therapy for neurometabolic disorders |
| EP1919497B1 (en) | 2005-07-22 | 2020-02-12 | The Board of Trustees of the Leland Stanford Junior University | Light-activated cation channel and uses thereof |
| US9238150B2 (en) * | 2005-07-22 | 2016-01-19 | The Board Of Trustees Of The Leland Stanford Junior University | Optical tissue interface method and apparatus for stimulating cells |
| US10052497B2 (en) * | 2005-07-22 | 2018-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US9274099B2 (en) | 2005-07-22 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Screening test drugs to identify their effects on cell membrane voltage-gated ion channel |
| US8926959B2 (en) * | 2005-07-22 | 2015-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| WO2007146046A2 (en) | 2006-06-07 | 2007-12-21 | Genzyme Corporation | Gene therapy for amyotrophic lateral sclerosis and other spinal cord disorders |
| WO2008086470A1 (en) | 2007-01-10 | 2008-07-17 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| WO2008101128A1 (en) | 2007-02-14 | 2008-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System, method and applications involving identification of biological circuits such as neurological characteristics |
| WO2008106694A2 (en) | 2007-03-01 | 2008-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Systems, methods and compositions for optical stimulation of target cells |
| EP2019143A1 (en) * | 2007-07-23 | 2009-01-28 | Genethon | CNS gene delivery using peripheral administration of AAV vectors |
| EP2058401A1 (en) | 2007-10-05 | 2009-05-13 | Genethon | Widespread gene delivery to motor neurons using peripheral injection of AAV vectors |
| US10434327B2 (en) | 2007-10-31 | 2019-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Implantable optical stimulators |
| US10035027B2 (en) * | 2007-10-31 | 2018-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Device and method for ultrasonic neuromodulation via stereotactic frame based technique |
| MY169771A (en) | 2008-04-23 | 2019-05-15 | Univ Leland Stanford Junior | Systems, methods and compositions for optical stimulation of target cells |
| WO2009148946A2 (en) * | 2008-05-29 | 2009-12-10 | The Board Of Trustees Of The Leland Stanford Junior University | Cell line, system and method for optical control of secondary messengers |
| EP2303405A4 (en) | 2008-06-17 | 2017-12-27 | The Board of Trustees of the Leland Stanford Junior University | Apparatus and methods for controlling cellular development |
| JP2011525130A (ja) | 2008-06-17 | 2011-09-15 | ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ | 光伝送素子を用いた標的細胞の光刺激のための方法、システム、および装置 |
| WO2010006049A1 (en) | 2008-07-08 | 2010-01-14 | The Board Of Trustees Of The Leland Stanford Junior University | Materials and approaches for optical stimulation of the peripheral nervous system |
| NZ602416A (en) | 2008-11-14 | 2014-08-29 | Univ Leland Stanford Junior | Optically-based stimulation of target cells and modifications thereto |
| JP5879256B2 (ja) * | 2009-05-02 | 2016-03-08 | ジェンザイム・コーポレーション | 神経変性障害のための遺伝子治療 |
| WO2011116238A2 (en) | 2010-03-17 | 2011-09-22 | The Board Of Trustees Of The Leland Stanford Junior University. | Light-sensitive ion-passing molecules |
| CN106106368A (zh) | 2010-11-05 | 2016-11-16 | 斯坦福大学托管董事会 | 光控cns功能障碍 |
| ES2684307T3 (es) | 2010-11-05 | 2018-10-02 | The Board Of Trustees Of The Leland Stanford Junior University | Proteínas estabilizadas de tipo opsina de función escalonada y métodos de uso de las mismas |
| CN106376525A (zh) | 2010-11-05 | 2017-02-08 | 斯坦福大学托管董事会 | 记忆功能的控制和表征 |
| CN106422081B (zh) | 2010-11-05 | 2019-06-21 | 斯坦福大学托管董事会 | 用于光遗传学方法的光的上转换 |
| WO2012061679A2 (en) | 2010-11-05 | 2012-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Light-activated chimeric opsins and methods of using the same |
| AU2011323235B2 (en) | 2010-11-05 | 2015-10-29 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic control of reward-related behaviors |
| US8696722B2 (en) | 2010-11-22 | 2014-04-15 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic magnetic resonance imaging |
| US20130164367A1 (en) * | 2011-12-08 | 2013-06-27 | The Board Of Regents Of The University Of Texas System | Treatment of neurodegenerative disease with creb-binding protein |
| CA2859364C (en) | 2011-12-16 | 2019-05-07 | The Board Of Trustees Of The Leland Stanford Junior University | Opsin polypeptides and methods of use thereof |
| EP3205374B1 (en) * | 2012-02-21 | 2019-03-27 | The Board of Trustees of The Leland Stanford Junior University | Compositions for treating neurogenic disorders of the pelvic floor |
| JP6469000B2 (ja) * | 2012-05-18 | 2019-02-13 | ユニバーシティー オブ アイオワ リサーチ ファウンデーション | アミロイドの沈着を処置するための方法および組成物 |
| JP6594854B2 (ja) | 2013-03-15 | 2019-10-23 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 行動状態の光遺伝学的制御方法 |
| US9636380B2 (en) | 2013-03-15 | 2017-05-02 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic control of inputs to the ventral tegmental area |
| AU2014260101B2 (en) | 2013-04-29 | 2018-07-26 | Humboldt-Universitat Zu Berlin | Devices, systems and methods for optogenetic modulation of action potentials in target cells |
| MX380973B (es) * | 2013-05-01 | 2025-03-12 | Genzyme Corp | Composiciones y metodos para tratar la atrofia muscular espinal. |
| GB201308917D0 (en) | 2013-05-17 | 2013-07-03 | Renishaw Plc | Delivery |
| EP3033427A4 (en) | 2013-08-14 | 2017-05-31 | The Board Of Trustees Of The University Of the Leland Stanford Junior University | Compositions and methods for controlling pain |
| WO2016209654A1 (en) | 2015-06-22 | 2016-12-29 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and devices for imaging and/or optogenetic control of light-responsive neurons |
| US11294165B2 (en) | 2017-03-30 | 2022-04-05 | The Board Of Trustees Of The Leland Stanford Junior University | Modular, electro-optical device for increasing the imaging field of view using time-sequential capture |
| EP3668891B1 (en) * | 2017-08-16 | 2023-07-26 | Lgv1 S.R.L. | Vtft isoform of a bpifb4 protein for use in neuronal deseases and injuries |
| JP7015605B2 (ja) * | 2019-12-27 | 2022-02-03 | 株式会社Rainbow | 頭蓋内に安全に細胞を投与するための総合システム |
| CN113755524B (zh) * | 2020-06-02 | 2023-11-03 | 舒泰神（北京）生物制药股份有限公司 | 用于治疗脊髓性肌萎缩的腺相关病毒载体及其用途 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4025A (en) * | 1845-05-01 | Feinting press | ||
| SE8303626D0 (sv) | 1983-06-23 | 1983-06-23 | Kabigen Ab | A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced |
| US5672344A (en) | 1987-12-30 | 1997-09-30 | The Regents Of The University Of Michigan | Viral-mediated gene transfer system |
| US5773278A (en) | 1991-05-03 | 1998-06-30 | Mount Sinai Medical Center | Acid sphingomyelinase gene |
| ES2249761T3 (es) | 1993-06-24 | 2006-04-01 | Advec Inc. | Vectores de adenovirus para terapia genica. |
| EP1637608B1 (en) | 1993-10-25 | 2009-07-22 | CANJI, Inc. | Recombinant adenoviral vector and methods of use |
| PT733103E (pt) | 1993-11-09 | 2004-07-30 | Targeted Genetics Corp | Criacao de elevados titulos de vectores de aav recombinantes |
| US7252989B1 (en) | 1994-04-04 | 2007-08-07 | Board Of Regents, The University Of Texas System | Adenovirus supervector system |
| CA2187626C (en) | 1994-04-13 | 2009-11-03 | Michael G. Kaplitt | Aav-mediated delivery of dna to cells of the nervous system |
| AU1525797A (en) | 1996-04-22 | 1997-11-12 | Medtronic, Inc. | Two-stage angled venous cannula |
| US6544785B1 (en) | 1998-09-14 | 2003-04-08 | Mount Sinai School Of Medicine Of New York University | Helper-free rescue of recombinant negative strand RNA viruses |
| AU1775901A (en) | 1999-11-17 | 2001-05-30 | Avigen, Inc. | Recombinant adeno-associated virus virions for the treatment of lysosomal disorders |
| US20030165481A1 (en) | 2000-02-24 | 2003-09-04 | Hersh Louis B. | Amyloid peptide inactivating enzyme to treat Alzheimer's disease |
| AU2001290984A1 (en) | 2000-09-18 | 2002-04-02 | Genzyme Corporation | Expression vectors containing hybrid ubiquitin promoters |
| US20030050273A1 (en) | 2001-08-29 | 2003-03-13 | Keiya Ozawa | Compositions and methods for treating neurodegenerative diseases |
| DK2359869T3 (en) * | 2001-12-17 | 2019-04-15 | Univ Pennsylvania | Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof |
| US6998118B2 (en) * | 2001-12-21 | 2006-02-14 | The Salk Institute For Biological Studies | Targeted retrograde gene delivery for neuronal protection |
| NZ533833A (en) | 2001-12-21 | 2008-01-31 | Salk Inst For Biological Studi | Targeted retrograde gene delivery to motor neurons |
| ES2562490T3 (es) | 2003-05-01 | 2016-03-04 | Genzyme Corporation | Terapia génica para trastornos neurometabólicos |
| US20040258666A1 (en) * | 2003-05-01 | 2004-12-23 | Passini Marco A. | Gene therapy for neurometabolic disorders |
| EP1716870A1 (en) | 2005-04-29 | 2006-11-02 | Bracco Imaging S.p.A. | MRI contrast agents endowed with concentration independent responsiveness |
| PL1879623T3 (pl) | 2005-05-02 | 2013-03-29 | Genzyme Corp | Terapia genowa zaburzeń rdzenia kręgowego |
| EP1879624B1 (en) | 2005-05-02 | 2011-09-21 | Genzyme Corporation | Gene therapy for neurometabolic disorders |
| JP5706602B2 (ja) | 2006-02-08 | 2015-04-22 | ジェンザイム・コーポレーション | ニーマンピック病ａ型に対する遺伝子治療 |
-
2006
- 2006-05-02 PL PL06752135T patent/PL1879623T3/pl unknown
- 2006-05-02 EP EP06752135A patent/EP1879623B1/en active Active
- 2006-05-02 AU AU2006242129A patent/AU2006242129A1/en not_active Abandoned
- 2006-05-02 JP JP2008510154A patent/JP5766389B2/ja active Active
- 2006-05-02 DK DK06752135.1T patent/DK1879623T3/da active
- 2006-05-02 ES ES06752135T patent/ES2394482T3/es active Active
- 2006-05-02 PT PT67521351T patent/PT1879623E/pt unknown
- 2006-05-02 CA CA2606490A patent/CA2606490C/en active Active
- 2006-05-02 WO PCT/US2006/016943 patent/WO2006119341A2/en not_active Ceased
- 2006-05-02 BR BRPI0611540-3A patent/BRPI0611540A2/pt not_active Application Discontinuation
- 2006-05-02 CN CN201610153759.2A patent/CN105770909A/zh active Pending
- 2006-05-02 MX MX2007013734A patent/MX2007013734A/es active IP Right Grant
-
2007
- 2007-10-30 IL IL187023A patent/IL187023A/en not_active IP Right Cessation
- 2007-11-02 US US11/934,148 patent/US10744210B2/en active Active
-
2012
- 2012-12-26 JP JP2012282826A patent/JP2013082731A/ja active Pending
-
2015
- 2015-03-10 IL IL237658A patent/IL237658A0/en unknown
- 2015-03-25 JP JP2015063153A patent/JP2015163613A/ja active Pending
-
2017
- 2017-02-23 JP JP2017032174A patent/JP2017132774A/ja active Pending
-
2019
- 2019-11-08 JP JP2019203155A patent/JP6887008B2/ja active Active
-
2020
- 2020-06-24 US US16/910,834 patent/US20210008227A1/en not_active Abandoned
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