JP2008506690A5 - - Google Patents

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Publication number
JP2008506690A5
JP2008506690A5 JP2007521565A JP2007521565A JP2008506690A5 JP 2008506690 A5 JP2008506690 A5 JP 2008506690A5 JP 2007521565 A JP2007521565 A JP 2007521565A JP 2007521565 A JP2007521565 A JP 2007521565A JP 2008506690 A5 JP2008506690 A5 JP 2008506690A5
Authority
JP
Japan
Prior art keywords
polymorph
decitabine
cancer
endotherm
polymorph form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007521565A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008506690A (ja
JP5159307B2 (ja
Filing date
Publication date
Priority claimed from US10/890,828 external-priority patent/US20060014949A1/en
Application filed filed Critical
Publication of JP2008506690A publication Critical patent/JP2008506690A/ja
Publication of JP2008506690A5 publication Critical patent/JP2008506690A5/ja
Application granted granted Critical
Publication of JP5159307B2 publication Critical patent/JP5159307B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2007521565A 2004-07-13 2005-07-12 デシタビンポリモルフの組成物及び処方物並びにその使用方法 Expired - Lifetime JP5159307B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/890,828 2004-07-13
US10/890,828 US20060014949A1 (en) 2004-07-13 2004-07-13 Compositions and formulations of decitabine polymorphs and methods of use thereof
PCT/US2005/024676 WO2006017278A1 (en) 2004-07-13 2005-07-12 Compositions and formulations of decitabine polymorphs and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2008506690A JP2008506690A (ja) 2008-03-06
JP2008506690A5 true JP2008506690A5 (https=) 2008-09-04
JP5159307B2 JP5159307B2 (ja) 2013-03-06

Family

ID=35600347

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007521565A Expired - Lifetime JP5159307B2 (ja) 2004-07-13 2005-07-12 デシタビンポリモルフの組成物及び処方物並びにその使用方法

Country Status (7)

Country Link
US (1) US20060014949A1 (https=)
EP (1) EP1765076A4 (https=)
JP (1) JP5159307B2 (https=)
CN (1) CN101014246A (https=)
AU (3) AU2005271814B2 (https=)
CA (1) CA2573332A1 (https=)
WO (1) WO2006017278A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7700567B2 (en) 2005-09-29 2010-04-20 Supergen, Inc. Oligonucleotide analogues incorporating 5-aza-cytosine therein
JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
WO2008044041A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
JO2778B1 (en) 2007-10-16 2014-03-15 ايساي انك Certain Compounds, Compositions and Methods
JP5687687B2 (ja) 2009-04-06 2015-03-18 大塚製薬株式会社 癌を治療するための(2’−デオキシ−リボフラノシル)−1,3,4,7−テトラヒドロ−(1,3)ジアゼピン−2−オン誘導体
WO2010129211A2 (en) * 2009-04-27 2010-11-11 Dr. Reddy's Laboratories Ltd. Preparation of decitabine
CN101781347B (zh) * 2009-12-21 2012-09-12 南京卡文迪许生物工程技术有限公司 地西他滨多晶型物和药用组合物
EP2750768B1 (en) 2011-08-30 2018-10-03 Astex Pharmaceuticals, Inc. Decitabine derivative formulations
EP2766041B1 (en) 2011-10-12 2018-12-05 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
US20140094598A1 (en) 2012-10-01 2014-04-03 Johnson Matthey Public Limited Company Method for the purification of decitabine
CN103191144B (zh) * 2013-04-25 2014-06-18 李伟丽 一种治疗癌症的药物组合物及应用
AU2016287585B2 (en) 2015-07-02 2020-12-17 Otsuka Pharmaceutical Co., Ltd. Lyophilized pharmaceutical compositions
WO2019025256A1 (en) 2017-08-01 2019-02-07 Bayer Aktiengesellschaft COMBINATION OF MIDH1 INHIBITORS AND DNA HYPOMETHYLATION (AHM) AGENTS
KR20200035438A (ko) 2017-08-03 2020-04-03 오쓰까 세이야꾸 가부시키가이샤 약물 화합물 및 이의 정제 방법
JP7089603B2 (ja) 2018-06-11 2022-06-22 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 眼疾患を治療するための脱メチル化
PH12022552250A1 (en) 2020-02-25 2023-11-13 Otsuka Pharma Co Ltd Combination decitabine and cedazuridine solid oral dosage forms
EP4138843A4 (en) 2020-04-23 2024-07-10 Southern Research Institute COMPOSITION FOR THE TREATMENT OF BLOOD CANCER USING 4'-THIO-5-AZA-2'-DEOXYCYTIDINE AND USES THEREOF
WO2022020747A1 (en) * 2020-07-23 2022-01-27 Southern Research Institute Polymorophs of 5-aza-4'-thio-2-deoxycytidine
CN119943194A (zh) * 2023-11-03 2025-05-06 中国石油天然气股份有限公司 一种分子筛晶胞参数确定方法和装置

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1050899A (https=) * 1963-12-22
CH527207A (de) * 1968-05-08 1972-08-31 Ceskoslovenska Akademie Ved Verfahren zur Herstellung von 1-Glycosyl-5-azacytosinen
DE2012888C3 (de) * 1970-03-14 1981-04-02 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 5-Azapyrimidinnucleosiden
JPS5213741B2 (https=) * 1972-05-22 1977-04-16
JPS5527077A (en) * 1978-08-16 1980-02-26 Shin Meiwa Ind Co Ltd Solids scraper for sludge dehydrator
US6613753B2 (en) * 2001-02-21 2003-09-02 Supergen, Inc. Restore cancer-suppressing functions to neoplastic cells through DNA hypomethylation
KR101150250B1 (ko) * 2001-03-01 2012-06-12 아보트 래버러토리즈 시스-ftc의 다형 및 기타 결정형
US20040162263A1 (en) * 2002-10-31 2004-08-19 Supergen, Inc., A Delaware Corporation Pharmaceutical formulations targeting specific regions of the gastrointesinal tract

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