JP2007509960A5 - - Google Patents

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Publication number
JP2007509960A5
JP2007509960A5 JP2006538253A JP2006538253A JP2007509960A5 JP 2007509960 A5 JP2007509960 A5 JP 2007509960A5 JP 2006538253 A JP2006538253 A JP 2006538253A JP 2006538253 A JP2006538253 A JP 2006538253A JP 2007509960 A5 JP2007509960 A5 JP 2007509960A5
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JP
Japan
Prior art keywords
disorders
pharmaceutical composition
composition according
nzojiazepin
depressive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2006538253A
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English (en)
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JP2007509960A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/035822 external-priority patent/WO2005044818A2/en
Publication of JP2007509960A publication Critical patent/JP2007509960A/ja
Publication of JP2007509960A5 publication Critical patent/JP2007509960A5/ja
Withdrawn legal-status Critical Current

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Description

図１ｂ、２ｂ、及び３ｂは、オープンアーム中滞在時間百分率対ｍｇ／ｋｇ（投与した化合物の用量）で表した本発明の様々な化合物のインビボ試験の結果を示すグラフである。

Claims (2)

  1. 不安障害、精神障害、痙攣性障害、攻撃的行動、筋痙攣若しくは緊張、抑鬱性若しくは双極性障害、認知障害、睡眠障害、神経変性眼疾患、神経変性、疼痛、嘔吐、又は摂食障害の治療用である、請求項１３に記載の医薬組成物。
  2. ベンゾジアゼピン受容体を阻害する、請求項１３又は１４に記載の医薬組成物。
JP2006538253A 2003-10-28 2004-10-28 イミダゾ［１，２−ａ］ピリジン抗不安薬 Withdrawn JP2007509960A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51504303P 2003-10-28 2003-10-28
PCT/US2004/035822 WO2005044818A2 (en) 2003-10-28 2004-10-28 Imidazo[1,2-a]pyridine anxiolytics

Publications (2)

Publication Number Publication Date
JP2007509960A JP2007509960A (ja) 2007-04-19
JP2007509960A5 true JP2007509960A5 (ja) 2007-11-29

Family

ID=34572796

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006538253A Withdrawn JP2007509960A (ja) 2003-10-28 2004-10-28 イミダゾ［１，２−ａ］ピリジン抗不安薬

Country Status (8)

Country Link
US (3) US7723324B2 (ja)
EP (1) EP1682549B1 (ja)
JP (1) JP2007509960A (ja)
AT (1) ATE482211T1 (ja)
AU (1) AU2004287847A1 (ja)
CA (1) CA2544213A1 (ja)
DE (1) DE602004029272D1 (ja)
WO (1) WO2005044818A2 (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009517469A (ja) * 2005-11-28 2009-04-30 マリンクロッド・インコーポレイテッド イミダゾールピリジンの改良された製造方法
EP1803722A1 (en) 2006-01-03 2007-07-04 Ferrer Internacional, S.A. Imidazo[1,2-a]pyridin-3-yl-acetic acid hydrazides, processes for their preparation and pharmaceutical uses thereof
AU2009249186B2 (en) * 2008-05-19 2014-05-22 Sunovion Pharmaceuticals Inc. Imidazo [1, 2-a] pyridine compounds as GABA-A receptor modulators
WO2011041713A2 (en) * 2009-10-02 2011-04-07 Glaxosmithkline Llc Piperazinyl antiviral agents
MX2012004990A (es) 2009-10-30 2012-06-12 Janssen Pharmaceutica Nv Deribados de imidazo [1,2-b] pirimideazina y su uso como inhibidores de la enzima fosfodiesterasa 10.
AR080754A1 (es) 2010-03-09 2012-05-09 Janssen Pharmaceutica Nv Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10
MX344600B (es) 2011-06-27 2016-12-20 Janssen Pharmaceutica Nv Derivados de 1-aril-4-metil-[1,2,4]triazolo[4,3-a]quinoxalina.
CN104411312B (zh) 2012-06-26 2018-03-06 詹森药业有限公司 包括pde2抑制剂例如1‑芳基‑4‑甲基‑[1,2,4]三唑[4,3‑a]‑喹喔啉化合物和pde10抑制剂的用于在治疗神经病学障碍或代谢障碍中使用的组合
RU2667058C2 (ru) 2012-07-09 2018-09-14 Янссен Фармацевтика Нв Ингибиторы фермента фосфодиэстеразы 10
ES2689429T3 (es) * 2012-07-13 2018-11-14 Ucb Biopharma Sprl Derivados de imidazopiridina como moduladores de actividad de TNF
TWI648281B (zh) * 2013-10-17 2019-01-21 日商安斯泰來製藥股份有限公司 含硫二環式化合物
TW201601632A (zh) 2013-11-20 2016-01-16 杜邦股份有限公司 １－芳基－３－烷基吡唑殺蟲劑
CN106715412B (zh) 2014-07-02 2019-11-26 Fmc公司 哌啶酮除草剂
US9926316B2 (en) * 2016-03-03 2018-03-27 The Cleveland Clinic Foundation Antitumor derivatives for differentiation therapy
CN107383005B (zh) * 2017-09-11 2020-03-13 华东理工大学 6-甲基-2-(4-甲基苯基)咪唑并[1,2-a]吡啶-3-乙酸的制备方法
CN113387946B (zh) * 2021-05-17 2023-08-01 衡阳师范学院 一种超声辅助多组分合成2-苯基-3-芳胺甲基咪唑并吡啶衍生物的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU522187A1 (ru) * 1975-03-12 1976-07-25 Военная Краснознаменная академия химической защиты им.Маршала Советского Союза С.К.Тимошенко Способ получени 3-ацил-2-алкил (арил)-имидазо (1,2 )пиридинов
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique
FR2525601A1 (fr) 1982-04-21 1983-10-28 Synthelabo Derives d'imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR2568880B1 (fr) * 1984-08-07 1986-12-12 Synthelabo Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
WO1986007059A2 (en) 1985-05-25 1986-12-04 Yoshitomi Pharmaceutical Industries, Ltd. Oxodiazine compounds
FR2647451B1 (fr) * 1989-05-26 1994-08-05 Sanofi Sa Derives d'imidazo(1,2-a)pyridine, procede de preparation, compositions pharmaceutiques les contenant
DE10040016A1 (de) * 2000-08-16 2002-02-28 Boehringer Ingelheim Pharma Neue beta-Amyloid Inhibitoren, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US6514969B2 (en) * 2000-08-16 2003-02-04 Boehringer Ingelheim Pharma Kg β-amyloid inhibitors, processes for preparing them, and their use in pharmaceutical compositions
SE0100567D0 (sv) 2001-02-20 2001-02-20 Astrazeneca Ab Compounds
SE0100568D0 (sv) 2001-02-20 2001-02-20 Astrazeneca Ab Compounds
US7196095B2 (en) 2001-06-25 2007-03-27 Merck & Co., Inc. (Pyrimidinyl) (phenyl) substituted fused heteroaryl p38 inhibiting and PKG kinase inhibiting compounds
CA2484631A1 (en) 2002-05-13 2003-11-27 Merck & Co., Inc. Phenyl substituted imidazopyridines and phenyl substituted benzimidazoles

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