JP2007508552A - マトリックス支援レーザー脱離/イオン化(maldi)質量分析法(ms)を包含する化学分析のための被検体の濃縮および精製のための方法および装置 - Google Patents
マトリックス支援レーザー脱離/イオン化(maldi)質量分析法(ms)を包含する化学分析のための被検体の濃縮および精製のための方法および装置 Download PDFInfo
- Publication number
- JP2007508552A JP2007508552A JP2006534450A JP2006534450A JP2007508552A JP 2007508552 A JP2007508552 A JP 2007508552A JP 2006534450 A JP2006534450 A JP 2006534450A JP 2006534450 A JP2006534450 A JP 2006534450A JP 2007508552 A JP2007508552 A JP 2007508552A
- Authority
- JP
- Japan
- Prior art keywords
- layer
- capture
- concentrator
- membrane
- porous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
- B01L3/50255—Multi-well filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Sampling And Sample Adjustment (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51161503P | 2003-10-10 | 2003-10-10 | |
| US58184304P | 2004-06-22 | 2004-06-22 | |
| US58609904P | 2004-07-07 | 2004-07-07 | |
| PCT/US2004/033471 WO2005036132A2 (en) | 2003-10-10 | 2004-10-12 | Methods and devices for concentration and purification of analytes for chemical analysis including matrix-assisted laser desorption/ionization (maldi) mass spectrometry (ms) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007508552A true JP2007508552A (ja) | 2007-04-05 |
| JP2007508552A5 JP2007508552A5 (https=) | 2007-11-29 |
Family
ID=34437675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006534450A Pending JP2007508552A (ja) | 2003-10-10 | 2004-10-12 | マトリックス支援レーザー脱離/イオン化(maldi)質量分析法(ms)を包含する化学分析のための被検体の濃縮および精製のための方法および装置 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7534338B2 (https=) |
| EP (1) | EP1676292A4 (https=) |
| JP (1) | JP2007508552A (https=) |
| CA (1) | CA2541536A1 (https=) |
| WO (1) | WO2005036132A2 (https=) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007192673A (ja) * | 2006-01-19 | 2007-08-02 | Shimadzu Corp | サンプルプレート |
| WO2010095677A1 (ja) * | 2009-02-18 | 2010-08-26 | 日本電気株式会社 | ターゲットプレートおよびその製造方法 |
| JP2011242159A (ja) * | 2010-05-14 | 2011-12-01 | Yokohama City Univ | 電気泳動で分離されたタンパク質を膜フィルターに転写し質量分析する方法 |
| JP2014512538A (ja) * | 2011-04-19 | 2014-05-22 | ポーレックス コーポレイション | 焼結多孔性プラスチックを含む試料貯蔵および送達のためのカード |
| JP2018533746A (ja) * | 2015-09-24 | 2018-11-15 | ゼーン ベアード, | 稀な細胞および無細胞分子の質量タグ分析 |
| JP2020165809A (ja) * | 2019-03-29 | 2020-10-08 | 浜松ホトニクス株式会社 | 試料支持体 |
| JP2024528879A (ja) * | 2021-08-02 | 2024-08-01 | エフ. ホフマン-ラ ロシュ アーゲー | マルチウェルプレート親油性アッセイ |
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|---|---|---|---|---|
| US7095018B2 (en) * | 2004-12-29 | 2006-08-22 | Wisconsin Alumni Research Foundation | Deposition of samples and sample matrix for enhancing the sensitivity of matrix assisted laser desorption/ionization mass spectrometry |
| US7829291B2 (en) * | 2005-02-17 | 2010-11-09 | Vanderbilt University | In situ analysis of tissues |
| US8153435B1 (en) | 2005-03-30 | 2012-04-10 | Tracer Detection Technology Corp. | Methods and articles for identifying objects using encapsulated perfluorocarbon tracers |
| US7109481B1 (en) * | 2005-04-28 | 2006-09-19 | Thermo Finnigan Llc | Matrix-assisted laser desorption and ionization (MALDI) sample plate releasably coupled to a sample plate adapter |
| EP1898799A1 (en) * | 2005-07-06 | 2008-03-19 | Medizinische Universität Graz | Device for and method of delivery and removal of substances in and from a tissue or vessel |
| WO2007046162A1 (ja) * | 2005-10-20 | 2007-04-26 | Japan Science And Technology Agency | 質量分析法に用いられる試料ターゲットおよびその製造方法、並びに当該試料ターゲットを用いた質量分析装置 |
| EP1963480A2 (en) * | 2005-12-08 | 2008-09-03 | Protein Discovery, Inc. | Methods and devices for concentration and fractionation of analytes for chemical analysis |
| KR20090028684A (ko) * | 2006-03-29 | 2009-03-19 | 칸젠 바이오테크날러지즈, 인코포레이티드 | 피크의 검출을 향상시키기 위한 여과용 장치 및 방법 |
| US7858928B2 (en) * | 2006-09-20 | 2010-12-28 | The United States of America Department of Health and Human Services | Nanostructured surfaces as a dual ionization LDI-DESI platform for increased peptide coverage in proteomic analysis |
| US20090071834A1 (en) * | 2007-06-08 | 2009-03-19 | Protein Discovery, Inc. | Methods and Devices for Concentration and Fractionation of Analytes for Chemical Analysis Including Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry (MS) |
| JP2012525591A (ja) * | 2009-04-27 | 2012-10-22 | プロテイン・デイスカバリー・インコーポレーテツド | プログラム可能な電気泳動ノッチフィルターシステムと方法 |
| CA2786412C (en) * | 2010-01-08 | 2018-02-06 | University Of Tasmania | Porous polymer monoliths, processes for preparation and use thereof |
| EP2567395B1 (en) * | 2010-05-07 | 2019-12-18 | UT-Battelle, LLC | System and method for extracting a sample from a surface |
| US8486703B2 (en) | 2010-09-30 | 2013-07-16 | Ut-Battelle, Llc | Surface sampling concentration and reaction probe |
| US8637813B2 (en) | 2010-10-01 | 2014-01-28 | Ut-Battelle, Llc | System and method for laser assisted sample transfer to solution for chemical analysis |
| US8519330B2 (en) | 2010-10-01 | 2013-08-27 | Ut-Battelle, Llc | Systems and methods for laser assisted sample transfer to solution for chemical analysis |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| WO2013006904A1 (en) | 2011-07-12 | 2013-01-17 | University Of Tasmania | Use of porous polymer materials for storage of biological samples |
| WO2014060483A1 (en) | 2012-10-17 | 2014-04-24 | Spatial Transcriptomics Ab | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
| EP3013983B1 (en) | 2013-06-25 | 2023-02-15 | Prognosys Biosciences, Inc. | Spatially encoded biological assays using a microfluidic device |
| JP2016534839A (ja) | 2013-09-16 | 2016-11-10 | ジョンソン・アンド・ジョンソン・イノベーション・エルエルシーJohnson & Johnson Innovation LLC | 境界層分離を組み込む、マイクロ流体器官補助装置 |
| EP3175390A1 (en) | 2014-08-01 | 2017-06-07 | Katholieke Universiteit Leuven | System for interpretation of image patterns in terms of anatomical or curated patterns |
| DE102014114426A1 (de) | 2014-10-06 | 2016-04-07 | Bruker Daltonik Gmbh | MALDI-Träger mit magnetisch gehaltener Federstahlplatte |
| JP6179682B2 (ja) * | 2015-01-22 | 2017-08-16 | 株式会社村田製作所 | 空隙配置構造体およびその製造方法 |
| FR3033409B1 (fr) * | 2015-03-03 | 2017-04-14 | Nicolas Ugolin | Electrodot : procede d'analyse d'echantillons biologiques en matrice de spots fixes par l'action d'un courant electrique conjuguee a une difference de pression |
| US10774374B2 (en) | 2015-04-10 | 2020-09-15 | Spatial Transcriptomics AB and Illumina, Inc. | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| WO2017038709A1 (ja) | 2015-09-03 | 2017-03-09 | 浜松ホトニクス株式会社 | 表面支援レーザ脱離イオン化法、質量分析方法、及び質量分析装置 |
| CN106796198B (zh) * | 2015-09-03 | 2020-06-30 | 浜松光子学株式会社 | 试样支撑体和试样支撑体的制造方法 |
| WO2017074934A1 (en) * | 2015-10-28 | 2017-05-04 | Wafergen, Inc. | Single cell capture with capture chips |
| EP3442062A4 (en) * | 2016-04-08 | 2019-12-18 | Idemitsu Kosan Co., Ltd. | BINDING AGENT FOR ELECTROCHEMICAL ELEMENT |
| FR3065652B1 (fr) * | 2017-04-27 | 2021-07-23 | Biomerieux Sa | Plaque d'analyse maldi-tof a support papier et son utilisation |
| WO2019155759A1 (ja) * | 2018-02-09 | 2019-08-15 | 浜松ホトニクス株式会社 | 試料支持体、試料のイオン化方法、及び質量分析方法 |
| JP7217714B2 (ja) | 2018-02-09 | 2023-02-03 | 浜松ホトニクス株式会社 | 試料支持体 |
| US12228480B2 (en) * | 2018-11-30 | 2025-02-18 | Revvity Health Sciences, Inc. | Biological sample preparation using electric fields |
| US12529094B2 (en) | 2018-12-10 | 2026-01-20 | 10X Genomics, Inc. | Imaging system hardware |
| EP3894590B1 (en) | 2018-12-10 | 2025-10-22 | 10X Genomics, Inc. | Methods of using master / copy arrays for spatial detection |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| KR102095784B1 (ko) * | 2019-04-26 | 2020-04-01 | 한국과학기술연구원 | 다수표본 마이크로어레이 및 이차이온질량분석기를 이용한 법과학 증거물 감식방법 및 장치 |
| US12157124B2 (en) | 2019-11-06 | 2024-12-03 | 10X Genomics, Inc. | Imaging system hardware |
| US12110541B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Methods for preparing high-resolution spatial arrays |
| US11768175B1 (en) | 2020-03-04 | 2023-09-26 | 10X Genomics, Inc. | Electrophoretic methods for spatial analysis |
| US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
| WO2021252499A1 (en) | 2020-06-08 | 2021-12-16 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
| WO2021252747A1 (en) | 2020-06-10 | 2021-12-16 | 1Ox Genomics, Inc. | Fluid delivery methods |
| EP4491742B1 (en) | 2020-09-18 | 2026-03-04 | 10X Genomics, Inc. | Sample handling apparatus and image registration methods |
| EP4729631A2 (en) | 2020-12-21 | 2026-04-22 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| EP4582555A3 (en) | 2021-06-03 | 2025-10-22 | 10X Genomics, Inc. | Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis |
| EP4305195A2 (en) | 2021-12-01 | 2024-01-17 | 10X Genomics, Inc. | Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis |
| EP4441711A1 (en) | 2021-12-20 | 2024-10-09 | 10X Genomics, Inc. | Self-test for pathology/histology slide imaging device |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003025578A2 (en) * | 2001-09-14 | 2003-03-27 | Peter James | Concentration of protein and/or peptides samples |
| WO2003078452A1 (en) * | 2002-03-12 | 2003-09-25 | Perseptive Biosystems, Inc. | Method and apparatus for the identification and qualification of biomolecules |
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| US3271198A (en) * | 1959-12-30 | 1966-09-06 | Ibm | Electrolytic semiconductor photocell |
| US5810989A (en) * | 1997-09-04 | 1998-09-22 | Motorola, Inc. | Photoelectric synthesis of DNA or protein probe arrays |
| US6167910B1 (en) * | 1998-01-20 | 2001-01-02 | Caliper Technologies Corp. | Multi-layer microfluidic devices |
| US6494614B1 (en) * | 1998-07-27 | 2002-12-17 | Battelle Memorial Institute | Laminated microchannel devices, mixing units and method of making same |
| DE60011390T2 (de) | 1999-01-28 | 2004-10-14 | Université De Genève | Verfahren und vorrichtung zur identifikation oder karakterisierung von polypeptiden |
| US20020122747A1 (en) * | 2000-09-19 | 2002-09-05 | Mingqi Zhao | Integrated microdevices for conducting chemical operations |
| US6716629B2 (en) * | 2000-10-10 | 2004-04-06 | Biotrove, Inc. | Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof |
| CA2434699A1 (en) * | 2001-01-17 | 2002-10-17 | Randall W. Nelson | An integrated high throughput system for the analysis of biomolecules |
| US6919046B2 (en) * | 2001-06-07 | 2005-07-19 | Nanostream, Inc. | Microfluidic analytical devices and methods |
| GB0120131D0 (en) * | 2001-08-17 | 2001-10-10 | Micromass Ltd | Maldi target plate |
| US7030373B2 (en) * | 2003-12-19 | 2006-04-18 | Applera Corporation | MALDI plate construction with grid |
-
2004
- 2004-10-12 EP EP04794742A patent/EP1676292A4/en not_active Withdrawn
- 2004-10-12 US US10/963,336 patent/US7534338B2/en not_active Expired - Fee Related
- 2004-10-12 JP JP2006534450A patent/JP2007508552A/ja active Pending
- 2004-10-12 CA CA002541536A patent/CA2541536A1/en not_active Abandoned
- 2004-10-12 WO PCT/US2004/033471 patent/WO2005036132A2/en not_active Ceased
-
2009
- 2009-04-06 US US12/419,126 patent/US20100133098A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003025578A2 (en) * | 2001-09-14 | 2003-03-27 | Peter James | Concentration of protein and/or peptides samples |
| WO2003078452A1 (en) * | 2002-03-12 | 2003-09-25 | Perseptive Biosystems, Inc. | Method and apparatus for the identification and qualification of biomolecules |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007192673A (ja) * | 2006-01-19 | 2007-08-02 | Shimadzu Corp | サンプルプレート |
| WO2010095677A1 (ja) * | 2009-02-18 | 2010-08-26 | 日本電気株式会社 | ターゲットプレートおよびその製造方法 |
| JP2011242159A (ja) * | 2010-05-14 | 2011-12-01 | Yokohama City Univ | 電気泳動で分離されたタンパク質を膜フィルターに転写し質量分析する方法 |
| JP2014512538A (ja) * | 2011-04-19 | 2014-05-22 | ポーレックス コーポレイション | 焼結多孔性プラスチックを含む試料貯蔵および送達のためのカード |
| US9101311B2 (en) | 2011-04-19 | 2015-08-11 | Porex Corporation | Cards for sample storage and delivery comprising sintered porous plastic |
| US9198609B2 (en) | 2011-04-19 | 2015-12-01 | Porex Corporation | Cards for sample storage and delivery comprising sintered porous plastic |
| JP2018533746A (ja) * | 2015-09-24 | 2018-11-15 | ゼーン ベアード, | 稀な細胞および無細胞分子の質量タグ分析 |
| JP2021121804A (ja) * | 2015-09-24 | 2021-08-26 | ゼーン ベアード, | 稀な細胞および無細胞分子の質量タグ分析 |
| JP7174802B2 (ja) | 2015-09-24 | 2022-11-17 | ゼーン ベアード, | 稀な細胞および無細胞分子の質量タグ分析 |
| JP2020165809A (ja) * | 2019-03-29 | 2020-10-08 | 浜松ホトニクス株式会社 | 試料支持体 |
| WO2020202729A1 (ja) * | 2019-03-29 | 2020-10-08 | 浜松ホトニクス株式会社 | 試料支持体 |
| JP7227823B2 (ja) | 2019-03-29 | 2023-02-22 | 浜松ホトニクス株式会社 | 試料支持体 |
| JP2024528879A (ja) * | 2021-08-02 | 2024-08-01 | エフ. ホフマン-ラ ロシュ アーゲー | マルチウェルプレート親油性アッセイ |
Also Published As
| Publication number | Publication date |
|---|---|
| US7534338B2 (en) | 2009-05-19 |
| WO2005036132A3 (en) | 2006-03-02 |
| EP1676292A4 (en) | 2009-01-07 |
| EP1676292A2 (en) | 2006-07-05 |
| CA2541536A1 (en) | 2005-04-21 |
| US20050116161A1 (en) | 2005-06-02 |
| US20100133098A1 (en) | 2010-06-03 |
| WO2005036132A2 (en) | 2005-04-21 |
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