JP2006506350A5 - - Google Patents
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- Publication number
- JP2006506350A5 JP2006506350A5 JP2004536018A JP2004536018A JP2006506350A5 JP 2006506350 A5 JP2006506350 A5 JP 2006506350A5 JP 2004536018 A JP2004536018 A JP 2004536018A JP 2004536018 A JP2004536018 A JP 2004536018A JP 2006506350 A5 JP2006506350 A5 JP 2006506350A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- substituted
- ring
- diethyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41026102P | 2002-09-12 | 2002-09-12 | |
| PCT/US2003/024805 WO2004024719A1 (en) | 2002-09-12 | 2003-08-27 | Substituted 1,4-pyrazine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006506350A JP2006506350A (ja) | 2006-02-23 |
| JP2006506350A5 true JP2006506350A5 (https=) | 2006-09-21 |
Family
ID=31994096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004536018A Abandoned JP2006506350A (ja) | 2002-09-12 | 2003-08-27 | 置換１，４−ピラジン誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20040116444A1 (https=) |
| EP (1) | EP1539736A1 (https=) |
| JP (1) | JP2006506350A (https=) |
| AR (1) | AR041125A1 (https=) |
| AU (1) | AU2003269949A1 (https=) |
| BR (1) | BR0314139A (https=) |
| CA (1) | CA2494975A1 (https=) |
| MX (1) | MXPA05002418A (https=) |
| TW (1) | TW200503717A (https=) |
| WO (1) | WO2004024719A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004099201A1 (en) * | 2003-05-09 | 2004-11-18 | Pharmacia & Upjohn Company Llc | Compounds as crf1 receptor antagonists |
| US20060211710A1 (en) * | 2005-03-17 | 2006-09-21 | Pfizer Inc | Substituted aryl 1,4-pyrazine derivatives |
| KR102598895B1 (ko) | 2016-07-12 | 2023-11-07 | 레볼루션 메디슨즈, 인크. | 다른자리 입체성 shp2 억제제로서의 2,5-이치환 3-메틸 피라진 및 2,5,6-3치환 3-메틸 피라진 |
| MX2019008695A (es) | 2017-01-23 | 2019-09-11 | Revolution Medicines Inc | Compuestos biciclicos como inhibidores alostericos de shp2. |
| MX2019008696A (es) | 2017-01-23 | 2019-09-13 | Revolution Medicines Inc | Compuestos de piridina como inhibidores de shp2 alostericos. |
| CA3074690A1 (en) | 2017-09-07 | 2019-03-14 | Revolution Medicines, Inc. | Shp2 inhibitor compositions and methods for treating cancer |
| MX2020003579A (es) | 2017-10-12 | 2020-07-22 | Revolution Medicines Inc | Compuestos de piridina, pirazina, y triazina como inhibidores de shp2 alostericos. |
| BR112020009757A2 (pt) | 2017-12-15 | 2020-11-03 | Revolution Medicines, Inc. | compostos policíclicos como inibidores alostéricos de shp2 |
| IL300091A (en) | 2018-05-01 | 2023-03-01 | Revolution Medicines Inc | C40-, c28-, and c-32-linked rapamycin analogs as mtor inhibitors |
| CN112368289B (zh) | 2018-05-01 | 2024-02-20 | 锐新医药公司 | 作为mtor抑制剂的c26-连接的雷帕霉素类似物 |
| AU2023275778A1 (en) | 2022-05-25 | 2024-12-12 | Revolution Medicines, Inc. | Methods of treating cancer with an mtor inhibitor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6159980A (en) * | 1996-09-16 | 2000-12-12 | Dupont Pharmaceuticals Company | Pyrazinones and triazinones and their derivatives thereof |
| PA8467401A1 (es) * | 1998-02-17 | 2000-09-29 | Pfizer Prod Inc | Procedimiento para tratar la insuficiencia cardiaca |
| CO5271670A1 (es) * | 1999-10-29 | 2003-04-30 | Pfizer Prod Inc | Antagonistas del factor de liberacion de corticitropina y composiciones relacionadas |
| CN1231473C (zh) * | 2000-02-16 | 2005-12-14 | 神经能质公司 | 取代的芳基吡嗪 |
-
2003
- 2003-08-27 US US10/649,299 patent/US20040116444A1/en not_active Abandoned
- 2003-08-27 EP EP03751841A patent/EP1539736A1/en not_active Withdrawn
- 2003-08-27 CA CA002494975A patent/CA2494975A1/en not_active Abandoned
- 2003-08-27 JP JP2004536018A patent/JP2006506350A/ja not_active Abandoned
- 2003-08-27 AU AU2003269949A patent/AU2003269949A1/en not_active Abandoned
- 2003-08-27 WO PCT/US2003/024805 patent/WO2004024719A1/en not_active Ceased
- 2003-08-27 BR BR0314139-0A patent/BR0314139A/pt not_active IP Right Cessation
- 2003-08-27 MX MXPA05002418A patent/MXPA05002418A/es not_active Application Discontinuation
- 2003-09-02 AR ARP030103176A patent/AR041125A1/es unknown
- 2003-09-10 TW TW092125064A patent/TW200503717A/zh unknown
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