JP2006182720A - Physiologically active substance - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a physiologically active substance efficiently ingesting nutrients derived from natural materials such as vitamins or amino acids in good balance. <P>SOLUTION: The physiologically active substance comprising un-baked coral calcium, a granule of a silk extract and a granule of a pollen extract is used as a nutritive assistance food. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a physiologically active substance that can be suitably used as a raw material for nutritional supplements, food additives, daily products, and the like.

  In recent years, it has been screamed that the physiological activity function declines due to the deterioration of living environment such as irregular eating habits, stress, lack of exercise, lack of sleep, processed foods, increased opportunities for eating out with many additives, contaminated air, etc. It's been a long time. Continuing such unhealthy life leads to death, quartet, obesity, high cholesterol, high blood pressure, and high blood sugar levels. It has been reported that 20 million people have diabetes, 326.1 million people with high blood pressure, and 16.2 million people with diabetes. In order to prevent such lifestyle-related diseases, it is necessary to ingest nutrients such as minerals, vitamins and amino acids essential for maintaining the physiologically active function of the human body in a balanced manner. For this reason, many dietary supplements for fully supplementing these nutrients have been proposed.

For example, Patent Document 1 proposes a dietary supplement containing minerals and amino acids, which is mainly composed of coral powder granules and branched chain amino acids.
Patent Document 2 proposes a composition comprising a peptide obtained by hydrolyzing silk protein as a bioactive composition containing amino acids excellent in immunostimulatory action, antioxidant action, and antitumor cancer promoting action. Yes.

Furthermore, Patent Document 3 proposes edible pollen as a dietary supplement containing amino acids, vitamins, and the like.
JP 2000-236535 A JP-A-11-139986 Japanese Patent Laid-Open No. 10-80251

  However, as described in Patent Documents 1 to 3 described above, although dietary supplements each containing a coral powder that is a natural material, a peptide obtained from silk protein, and edible pollen each have been proposed, these Currently, no dietary supplement containing two or more natural ingredients has been proposed. For this reason, in order to ingest all nutrients such as minerals, vitamins, and amino acids derived from natural materials, the user must appropriately select and ingest the dietary supplements described in Patent Documents 1 to 3 described above. It was difficult to take in an optimal balance.

  Until now, Western medicine has played a major role in the treatment of lifestyle-related diseases such as cancer, stroke and heart disease. However, as I mentioned earlier, the reality that many people go to doctors and work while receiving medication is that data analysis, medication, and surgery, which are good at Western medicine, are no longer sufficient. I can't say that. It is normal to wait for an MRI examination reservation for half a year, and cancer hospitalization and surgery are often heard in months and casual conversations waiting for bed availability. In the current situation where the hospital is not catching up with the sick, it is hard to say that this is normal because the sick must be treated according to the hospital schedule.

In addition, we live with viruses and microorganisms, but the environment has been improved, and we are in Western medicine with advanced testing techniques. Recently, airborne infections can occur due to dry vomiting. There is concern about infection.
If the consciousness that prevention can be the best treatment is not made, it will be exposed to the invasion of viruses and microorganisms, and the response will be delayed.

In addition, given the aging society and the decreasing number of children that support it, self-medication prior to illness in Japan is an urgent need.
If the body has a self-defense function, it is possible to eliminate such foreign substances without leading to onset. In general, the interest in food is weak, the basic physical strength is reduced, and stress, infections (influenza, AIDS, etc.), food additives and chemicals such as residual agricultural chemicals and chemical fertilizers are affected, thereby The function is now in great danger.

On the other hand, because it changed to a diet that is less likely to stand in the kitchen, the chances of eating out with increased fat content have increased, resulting in a diet low in dietary fiber, vitamins and minerals.
Due to this imbalance of nutrient intake, hormones and enzymes that work to remove active oxygen generated in the body are not sufficiently activated, and cells may be damaged.
If normal cells are damaged by the effects of harmful active oxygen, they can trigger various diseases.

In other words, we entered the era of accepting the living environment given from the outside as it is, getting away from the idea of having a doctor cure if we get sick, and having a new recognition that we can maintain our health through self-management.
From such a background, the usefulness of foods containing a large amount of antioxidant components such as vitamin E and vitamin C has been pointed out.

Considering that human beings are also living on the earth, it is necessary to consider the importance of ingesting foods from the natural world as much as possible and the entire ingredients.
This invention is made | formed in view of the said situation, and it aims at providing the physiologically active substance which can take in nutrients, such as a mineral derived from a natural material, a vitamin, and an amino acid in a well-balanced and efficient manner. Yes. That is, an object of the present invention is to utilize a technique far beyond an artificial level, which is a “species conservation instinct” of living creatures, for food.

In order to solve such problems, the first physiologically active substance according to the present invention is characterized in that it contains uncalcined coral calcium, silk extract, and pollen extract.
According to this, minerals derived from uncalcined coral calcium, amino acids derived from silk extract, and nutrients such as vitamins, minerals and amino acids derived from pollen extract can be ingested in a balanced and efficient manner.

The second physiologically active substance according to the present invention is characterized by containing unfired coral calcium and a silk extract.
According to this, the mineral derived from unbaked coral calcium and the amino acid derived from the silk extract can be ingested in a balanced and efficient manner.
The third physiologically active substance according to the present invention is characterized in that it contains unbaked coral calcium and a pollen extract.

According to this, it is possible to ingest the mineral derived from the uncalcined coral calcium and the nutrients such as vitamins, minerals and amino acids derived from the pollen extract with good balance and efficiency.
The fourth physiologically active substance according to the present invention is characterized by containing a silk extract and a pollen extract.
According to this, amino acids derived from silk extract and nutrients such as vitamins, minerals and amino acids derived from pollen extract can be ingested with good balance and efficiency.

  In the physiologically active substance according to the present invention, the unfired coral calcium is preferably contained in the range of 10% by mass to 98.9% by mass with respect to the total mass, and is 10% by mass to 50% by mass. More preferably, it is contained in the range of. In particular, when the physiologically active substance according to the present invention is used as a dietary supplement, it is preferable that uncalcined coral calcium is contained in the range of 10% by mass to 40% by mass with respect to the total mass. When the physiologically active substance according to the above is used as a food additive, it is preferable that uncalcined coral calcium is contained in the range of 95% by mass or more and 98.9% by mass or less with respect to the total mass.

  Here, when the content ratio of the unfired coral calcium is less than 10% by mass, the minerals necessary for imparting the bioactive function are not sufficiently contained, while when it is more than 98.9% by mass, the nutrition is When used as a supplement, the taste as a food is impaired, and when used as a food additive, the obtained effect reaches a peak while the cost increases.

  In the physiologically active substance according to the present invention, the silk extract is preferably contained in the range of 0.5% by mass to 60% by mass with respect to the total mass, and is preferably 1% by mass to 50% by mass. More preferably, it is contained in the range of. In particular, when the physiologically active substance according to the present invention is used as a dietary supplement, the silk extract is preferably contained in a range of 1% by mass to 40% by mass with respect to the total mass. When a physiologically active substance is used as a food additive, the silk extract is preferably contained in a range of 0.5% by mass to 1% by mass with respect to the total mass.

  Here, when the content of the silk extract is less than 0.5% by mass, amino acids necessary for imparting a physiologically active function are not sufficiently contained. When used as, the balance with other materials is lost, and the cost is increased economically. When it is used as a food additive, if it exceeds 1% by mass, it becomes turbid and can be used as water. It will be difficult.

  Furthermore, in the physiologically active substance according to the present invention, the pollen extract is preferably contained in the range of 1% by mass to 50% by mass with respect to the total mass, and in the range of 5% by mass to 40% by mass. More preferably, it is contained. In particular, when the physiologically active substance according to the present invention is used as a dietary supplement, the pollen extract is preferably contained in a range of 10% by mass to 20% by mass with respect to the total mass. However, since the pollen extract is hardly soluble in water, it is preferable not to add it when the physiologically active substance according to the present invention is used as a food additive.

Here, when the content of the pollen extract is less than 1% by mass, amino acids and vitamins necessary for imparting a physiologically active function are not sufficiently contained. When used as, the blending ratio of pollen becomes higher than other materials, and the active ingredients of other materials are not satisfied.
The first to fourth physiologically active substances according to the present invention preferably further contain a rosehip extract. Thereby, the vitamin derived from a rosehip extract can be further ingested. In particular, when unfired coral calcium is contained as a raw material, minerals from the unfired coral calcium are easily extracted.

  This rosehip extract is preferably contained in the range of 1% by mass to 30% by mass with respect to the total mass of the physiologically active substance, and is preferably contained in the range of 5% by mass to 25% by mass. More preferably. In particular, when the physiologically active substance according to the present invention is used as a dietary supplement, it is preferable that the rosehip extract is contained in a range of 10% by mass to 20% by mass with respect to the total mass. When such a physiologically active substance is used as a food additive, it is preferable that the rosehip extract is contained in a range of 1% by mass to 5% by mass with respect to the total mass.

Here, when the content of the rosehip extract is less than 1% by mass, the effect of extracting minerals from the unbaked coral calcium is not sufficiently obtained, and when it exceeds 30% by mass, it is used as a dietary supplement. The ratio of rosehip extract is higher than other ingredients, the active ingredients of other ingredients are not satisfied, and when used as a food additive, the color and acidity are stronger than lycopene, Use becomes difficult.
The first and fourth physiologically active substances according to the present invention preferably further contain dolomite. Thereby, the mineral derived from dolomite containing much magnesium can be further ingested.

The dolomite is preferably contained in the range of 10% by mass to 40% by mass, and preferably in the range of 10% by mass to 30% by mass with respect to the total mass of the physiologically active substance. Further preferred. In particular, when the physiologically active substance according to the present invention is used as a dietary supplement, dolomite is preferably contained in a range of 10% by mass to 20% by mass with respect to the total mass. However, dolomite is preferably not added when the physiologically active substance according to the present invention is used as a food additive.
Here, when the content of dolomite exceeds 40) mass%, when used as a dietary supplement, the taste as a food is impaired.

Hereinafter, the material contained in the physiologically active substance in the present invention will be described in detail.
<About uncalcined coral calcium>
The uncalcined coral calcium contained in the present invention is a natural material obtained by washing, sterilizing, and drying weathered reef-building coral, and in addition to calcium, magnesium, sodium, phosphorus, potassium, iron, cobalt, nickel It contains minerals necessary for the human body such as copper, zinc, strontium and molybdenum.

<About silk extract>
The silk extract contained in the present invention is a natural material composed of a peptide (compound in which two or more amino acids are peptide-bonded) obtained by hydrolyzing silk protein, and has an immunostimulatory action, an antioxidant action, and an antitumor cancer promotion. It has an action.
<About pollen extract>
The pollen extract contained in the present invention is a natural material collected from a flower (insect flower) that is pollinated in the middle of an insect like bee pollen, for example, in addition to amino acids and vitamins, minerals, proteins, Contains enzymes, sugars, etc.

<About Rosehip Extract>
The rosehip extract contained in the present invention is a natural material obtained from the outer skin portion of dried rosehip (the bulging portion of the rose root), and contains vitamins such as vitamin C.
<About Dolomite>
The dolomite contained in the present invention is a natural material that ideally contains calcium and magnesium in a ratio of 2 to 1. For example, after coral accumulates on the sea floor and forms limestone, A finely pulverized bio-derived ore produced by replacing the magnesium with seawater in the part is preferably used.

  According to the physiologically active substance of the present invention, nutrients such as minerals, vitamins and amino acids derived from natural materials can be taken in a balanced and efficient manner. Therefore, lifestyle-related diseases can be effectively and efficiently prevented by using this physiologically active substance as a dietary supplement or food additive.

Embodiments of the present invention will be described below with reference to the drawings.
<First embodiment>
This embodiment demonstrates the case where the physiologically active substance which concerns on this invention is used as a dietary supplement.
This physiologically active substance is composed of 16.67% by mass of unbaked coral powder, 1.67% by mass of silk extract, 11.12% by mass of pollen powder, and 5.56% by mass of the total mass. It is a mixed powder containing rose hips and 14.17% by mass of dolomite.

Further, this physiologically active substance, in order to further act physiologically active functions from natural materials described above, further Benimen extract, casein phosphopeptide, vitamin E, vitamin D, vitamin B _1, vitamin B _12, L- It contains sodium ascorbate, folic acid, rutin, β-carotene, lycopene, astaxanthin, raffinose, grape seed extract, ferric pyrophosphate and the like.

And the physiologically active substance which consists of a mixed granular material enclosed by predetermined amount (for example, 1.8 g) in the substantially rectangular aluminum bag is drunk as it is or in the state mixed with drinks.
According to this physiologically active substance, minerals such as calcium derived from unfired coral, minerals such as magnesium derived from dolomite, amino acids such as glutamic acid and arginic acid derived from silk extract, and amino acids such as isoleucine and tryptophan derived from pollen In addition, vitamins such as vitamin B ₂ and vitamin E, minerals such as magnesium and iron, enzymes such as amylase and jastase, and vitamins such as vitamin C derived from rosehip powder can be ingested.

That is, by using this physiologically active substance as a dietary supplement, high quality minerals derived from natural materials, amino acids, vitamins and other nutrients can be taken in a balanced and efficient manner.
Therefore, by drinking nutritional supplements consisting of these physiologically active substances, nutrients such as minerals, amino acids, and vitamins derived from natural materials are ingested in a well-balanced body, improving the physiological activity of the human body and improving lifestyle Disease prevention is possible.

Next, a method for producing such a physiologically active substance will be described with reference to FIG.
FIG. 1 is a flowchart showing another example of a method for producing a physiologically active substance according to the present invention.
First, as shown in FIG. 1, unfired coral powder (trade name “Coral Bio PW”, manufactured by Okinawa Products Co., Ltd.) and silk extract powder (trade name “Edible Silk”, Ichimaru Falcos Co., Ltd. Company-made), pollen powder (trade name "pollen powder", native magic Okinawa limited company), rosehip powder and dolomite (trade name "Okinawa Dolomite", manufactured by Okinawa Products Co., Ltd.) Then, the materials other than these are weighed so as to have the following content rates (step S1).

[Content ratio with respect to the total mass of the mixed powder]
・ Unfired coral: 16.67%
-Silk extract: 1.67%
Pollen extract: 11.12%
・ Rose hip extract: 5.56%
-Dolomite: 14.17%
・ Other ingredients {Red noodle extract: 0.2%, Casein phosphopeptide: 0.16%, Vitamin E: 1.67%, Vitamin D: 0.02%, Vitamin B ₁ : 0.03%, Vitamin B ₁₂ : 0.03%, sodium L-ascorbate: 15.56%, folic acid: 0.01%, rutin: 0.07%, β-carotene: 0.57%, lycopene: 0.07%, astaxanthin: 0 0.07%, raffinose: 2.83%, grape seed extract: 1.89%, ferric pyrophosphate: 0.58%, balance (lactic acid, maltose, trehalose, calcium triphosphate, flavor, pullulan, sweetener) : 25.97%}

Next, the granular material of each content rate was preliminarily blended to obtain a mixed granular material (step S2). Here, by carrying out preliminary blending as a pretreatment for granulation and main blending, it is possible to evenly mix the silk extract powder having a low content.
Next, these mixed powders were granulated and adjusted to a desired particle size (step S3).
Next, this mixed powder after granulation was mixed (step S4). Thereafter, an appearance inspection, a water content inspection, a bulk density inspection, a particle diameter inspection, and a fungus inspection were performed to complete a physiologically active substance.
Then, the physiologically active substance composed of the granular material thus obtained was sealed in a predetermined amount in a substantially rectangular aluminum bag to obtain a finished shape.

<Second embodiment>
In this embodiment, a case where the physiologically active substance according to the present invention is used as a food additive to drinking water will be described.
This physiologically active substance comprises 87.3% by mass of unfired coral, 10% by mass of silver-added unsintered coral (coral to which silver has been added), 1% by mass of silk extract, 1% by mass of rosehip powder and 0.7% by mass of sodium L-ascorbate mixed powder, filled in a predetermined amount (for example, 1 g) in a filter paper bag. Yes.
Then, a filter paper bag filled with the physiologically active substance is immersed in a predetermined amount (for example, 500 ml) of drinking water for a predetermined time (for example, several minutes), whereby a nutrient having a physiologically active function in the drinking water. Is granted.

According to the physiologically active substance of the present embodiment, minerals such as calcium are extracted from unburned corals in drinking water, amino acids such as glutamic acid and arginine are extracted from silk extract, and vitamins such as vitamin C are extracted from rosehips. In addition, nutrients such as minerals, amino acids and vitamins derived from natural materials can be imparted in a balanced and efficient manner.
Moreover, the mineral derived from unbaked coral becomes easy to be extracted by containing rose hips.
Therefore, by drinking drinking water in which a food additive made of this physiologically active substance is soaked, nutrients such as minerals, amino acids and vitamins derived from natural materials are ingested in a well-balanced body, so that the physiologically active function of the human body Will improve and prevent lifestyle-related diseases.

Next, a method for producing such a physiologically active substance will be described with reference to FIG.
FIG. 2 is a flowchart showing an example of a method for producing a physiologically active substance according to the present invention.
First, as shown in FIG. 2, coral granules (trade name “Coral Bio RF”, manufactured by Okinawa Products Co., Ltd.) and coral granules added with silver (trade name “Coral Bio SI”, Okinawa Products Co., Ltd.). ), Silk extract powder (trade name “Edible Silk”, manufactured by Ichimaru Falcos), rosehip powder, and sodium L-ascorbate powder (trade name “L-ascorbine”). “Sodium acid” (manufactured by Happo Shokai Co., Ltd.) was weighed so as to have the following content (step S10).

[Abundance with respect to the total mass of the mixed powder]
・ Unfired coral: 87.3 mass%
-Coral added with silver: 10% by mass
・ Silk extract: 1% by mass
・ Rose hip powder: 1% by mass
-Sodium L-ascorbate: 0.7% by mass
And the granular material of each content rate was mixed (step S20), and the physiologically active substance was completed.
Here, the inclusion of sodium L-ascorbate has an effect of decomposing chlorine in tap water by reducing power.
Furthermore, since coral to which silver is added is contained, it has an effect of antibacterial action of drinking water.
Then, the physiologically active substance composed of the granular material thus obtained was sealed in a predetermined amount in a substantially rectangular filter paper bag to obtain a finished shape.

Hereinafter, the result of verifying the effect of the present invention will be described.
In this example, the nutritional supplement made of the physiologically active substance shown in the first embodiment is applied 3 times a day (1 per time) to 30 adult men and women who complain of stiff shoulders, coldness of the waist and limbs, and headache. Bag) After drinking for 10 days, about 30% of people got a result that stiff shoulders, lower back and limbs, and headache symptoms were improved.

  Based on the above results, it is possible to improve daily discomfort and cool the shoulders, waist and limbs by drinking dietary supplements consisting of bioactive substances including unbaked coral calcium, silk extract, and pollen extract. Go back to a comfortable life without headaches. There is not much research in modern medicine on daily life discomfort. This is because it cannot be expressed as a number. If this daily discomfort is taken as the beginning of the sick reserve army, it is the body's attention signal itself. If you ask what the body is moving, you can see that it is by "food". It was confirmed that the bias in eating habits could be improved by slightly supplementing with natural amino acids, minerals and vitamins.

The physiologically active substance of the present invention can be suitably used as a raw material for nutritional supplements, food additives, daily products, and the like.
More specifically, it can be blended into foods and drinks, luxury goods, livestock and pet feeds, cosmetics, bath preparations, oral medicines, external medicines, injections, drops, suppositories, and other medical preparations. is there.
In addition, food and drink products are processed fishery products such as kamaboko, chikuwa and hanpen, processed meat products such as sausage, ham and wiener, processed agricultural products such as tofu, fried chicken and konjac, Western confectionery, Japanese confectionery, bread, cake and jelly. , Pudding, snacks, cookies, gum, candy, ramune and other confectionery, raw noodles, Chinese noodles, buckwheat, udon noodles, sauces, soy sauce, dressing, mayonnaise, sauce, honey, powdered candy, syrup, and other seasonings, curry Spices such as flour, mustard powder, pepper powder, jam, marmalade, chocolate spread, pickles, soy sauce, sprinkles, processed vegetables and fruits such as canned and bottled vegetables and fruits, milk such as cheese, butter and yogurt Products, fruit juices, vegetable juices, whey drinks, soft drinks, health teas, medicinal liquors Beverages, other tablets for health such as nutraceutical the (nutraceutical) purposes, beverages, food products such health-oriented granulate, etc., animal feed, pet foods and the like as a target.

  Examples of cosmetics include lotion, milky lotion, cream, ointment, shaving mousse, oil, pack, shampoo, rinse, treatment, hair tonic, hair conditioner, hair restorer, permanent solution, hair dye. Skin care and hair care preparations such as body soaps, or bath preparations (any form such as liquid, powder, granule, solid, etc. may be used).

  Apart from these, sanitary products, wet tissue paper and paper towels, or cotton, scratches, cuts, burns, scratches, inflammation, eczema, pimples, acne, rough skin, etc. It can also be applied to preparations and gauze impregnated with them, adhesive bandages, eye care agents, inhalants, mouth washes, gargles, dentifrices and the like.

It is a flowchart which shows an example of the manufacturing method in the case of using the bioactive substance of this invention as a dietary supplement. It is a flowchart which shows an example of the manufacturing method in the case of using the bioactive substance of this invention as a food additive.

Claims (9)

  A physiologically active substance characterized by containing unbaked coral calcium, silk extract, and pollen extract.   A physiologically active substance comprising uncalcined coral calcium and silk extract.   A physiologically active substance comprising uncalcined coral calcium and a pollen extract.   A physiologically active substance comprising a silk extract and a pollen extract.   4. The physiologically active substance according to claim 1, wherein the uncalcined coral calcium is contained in a range of 10% by mass to 40% by mass or less with respect to the total mass. .   The physiologically active substance according to any one of claims 1, 2, and 4, wherein the silk extract is contained in a range of 8% by mass to 60% by mass with respect to the total mass.   5. The physiologically active substance according to claim 1, wherein the pollen extract is contained in a range of 8% by mass to 20% by mass with respect to the total mass.   The physiologically active substance according to any one of claims 1 to 7, further comprising a rosehip extract.   The physiologically active substance according to any one of claims 1 to 8, further comprising dolomite.

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