JP2006181088A - Medical wire - Google Patents

Medical wire Download PDF

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Publication number
JP2006181088A
JP2006181088A JP2004377574A JP2004377574A JP2006181088A JP 2006181088 A JP2006181088 A JP 2006181088A JP 2004377574 A JP2004377574 A JP 2004377574A JP 2004377574 A JP2004377574 A JP 2004377574A JP 2006181088 A JP2006181088 A JP 2006181088A
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member
medical wire
connecting member
indwelling equipment
intracorporeal indwelling
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JP2004377574A
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Japanese (ja)
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Hiroo Iwata
博夫 岩田
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Kyoto Univ
国立大学法人京都大学
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Priority to JP2004377574A priority Critical patent/JP2006181088A/en
Publication of JP2006181088A publication Critical patent/JP2006181088A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B21MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21FWORKING OR PROCESSING OF METAL WIRE
    • B21F35/00Making springs from wire
    • B21F35/006Double twist coil springs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12009Implements for ligaturing other than by clamps or clips, e.g. using a loop with a slip knot
    • A61B17/12013Implements for ligaturing other than by clamps or clips, e.g. using a loop with a slip knot for use in minimally invasive surgery, e.g. endoscopic surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • A61B17/12145Coils or wires having a pre-set deployed three-dimensional shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • A61B2017/12054Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12068Details concerning the detachment of the occluding device from the introduction device detachable by heat
    • A61B2017/12077Joint changing shape upon application of heat, e.g. bi-metal or reversible thermal memory
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires

Abstract

<P>PROBLEM TO BE SOLVED: To provide a medical guide wire which does not invade living tissues by direct heating of an indwelling device and can be easily separated from the indwelling device. <P>SOLUTION: The medical wire is constituted so that an indwelling device 2 is connected to an end of an electroconductive linear member 1 through an electrical insulating member 4 and a connecting member 3, the connecting member is made from a shape-memory alloy, the connecting member is transformed by heating when high-frequency current is supplied to the linear member, and the indwelling device is cut off by said transformation. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

本発明は、生体内の所定の個所に体内留置具を留置させるための医療用ワイヤーに関する。 The present invention relates to a medical wire for causing the placement of the intracorporeal indwelling equipment in a predetermined location in the body.

医療用ワイヤーは、通常、血管内治療(例えば動脈瘤、動静脈奇形、動静脈瘻または腫瘍の治療)に用いられている。 Medical wire is usually endovascular (e.g. an aneurysm, arteriovenous malformation, treatment of arteriovenous fistula or tumor) is used to. このような血管内治療は、医療用ワイヤーを用いて、生体内の所定の箇所に体内留置具を設置することにより実施される。 Such endovascular therapy using medical wire is carried out by placing the intracorporeal indwelling equipment at a predetermined point in vivo.
例えば医療用ワイヤーが動脈瘤の治療に適用される場合には、体内留置具として白金からなる二次コイルが用いられ、医療用ワイヤー先端の二次コイルを動脈瘤の瘤内に設置することにより動脈瘤の治療が行われる。 If for example, the medical wire is applied to the treatment of aneurysms, secondary coil made of platinum is used as the intracorporeal indwelling equipment, the medical wire tip of the secondary coil by placing within aneurysm aneurysms treatment of aneurysms is performed. 設置作業は、通常、二次コイルと医療用ワイヤーの線状部材(ガイドワイヤー)とを分離することにより行われ、分離手段としては、電気分解法を利用する方法、接続部材としてポリビニルアルコール(PVA樹脂)などを用い、該PVA樹脂を溶断して分離する方法、二次コイルとガイドワイヤーとをネジ構造にて接合し、ネジを取り外して分離する方法が従来から用いられてきた。 Installation work is usually carried out by separating the secondary coil and the linear member of the medical wire (guide wire), the separating means, a method of utilizing electrolysis, polyvinyl alcohol (PVA as a connecting member using a resin), a method of separating by fusing the PVA resin, and bonding the secondary coil and the guide wire by a screw structure, a method of separating and remove the screws have been used conventionally.
しかしながら、これら従来の分離手段を用いた場合、二次コイルの設置が何度も繰り返し行われるため、二次コイルとガイドワイヤーとの分離作業に膨大な時間や手間を必要とし、また、ポリビニルアルコール樹脂を前もって生理食塩水になじませる手間を必要とし、手術時間の長期化、医者や患者への負担の増大といった問題が生じる。 However, when using these conventional separation means, for the installation of the secondary coil is repeated many times, and requires an enormous amount of time and labor for the separation work of the secondary coil and the guide wire, also polyvinyl alcohol resin previously requiring labor adapt to saline, prolonged operative time, is a problem increasing burden on the physician and patient occur.

また、特許文献1には、上記した従来の分離手段の他に、医療用ワイヤーの接続部材に形状記憶合金を用いて、形状記憶合金を形状変化させて、体内留置具とガイドワイヤーとを分離する方法が記載されており、形状記憶合金を変化させる手段として、熱水を用いる方法および高周波電流を用いる方法が記載されている。 In Patent Document 1, the separation in addition to the conventional separation means described above, by using a shape memory alloy to the connecting member of the medical wire, shape memory alloys by shape change, and a guide wire intracorporeal indwelling equipment It describes a method of, as a means for changing the shape memory alloy, a method of using the method and high-frequency current used hot water is described.
熱水を用いる方法は、例えば脳動脈瘤の治療に医療用ワイヤーが適用される場合、上記した問題に加えて、熱水の注入地点から接続部材に至るまでの距離が長くなり、接続部材に熱水が到達するまでに、熱水の熱が血液に吸収されたりして、熱が冷めるなどの問題があり、また、熱水の温度を上げると生体に影響を及ぼす恐れがあった。 Methods using hot water, for example when a medical wire in the treatment of cerebral aneurysms are applied, in addition to the problems described above, the distance up to the connecting member from the injection point of the hot water is increased, the connecting member until hot water is reached, the heat of the hot water is or is absorbed into the blood, there are problems such as heat cools, also there may affect the living body when raising the temperature of the hot water.
高周波電流を用いる方法は、接続部分だけでなく、体内留置具まで熱されてしまうため、体内留置具周辺の生体組織への侵襲が生じるという問題があった。 A method using a high frequency current, as well as connection portion, for thereby being heated up intracorporeal indwelling equipment, there is a problem that the invasion of the intracorporeal indwelling equipment peripheral living tissue caused.
また、特許文献1には、接続部材に形状記憶樹脂を用いてもよい旨記載されているが、形状記憶樹脂の形状記憶特性や変形精度が良好でなく、医療用として形状記憶樹脂を用いるにはまだまだ満足のいくものではなかった。 Further, in Patent Document 1, the connection member are described that may also be used to shape-memory resin, but not good shape memory properties and deformation accuracy of the shape memory resin, a shape memory resin as a medical It did not go still satisfactory is.
特開平7−265431号公報 JP-7-265431 discloses

本発明は、体内留置具の直接加熱による生体組織への侵襲がなく、容易に体内留置具とガイドワイヤーとを分離することができる医療用ガイドワイヤーを提供することを主たる目的とする。 The present invention is not invasive to the living body tissue by direct heating of the intracorporeal indwelling equipment, easily a main object to provide a medical guide wire which can be separated from the intracorporeal indwelling equipment and the guide wire.

本発明者らは、上記目的を達成すべく鋭意検討した結果、体内留置具とガイドワイヤーとの接続部材を形状記憶合金とし、該接続部材の片端に電気絶縁部材を設けて高周波電流による加熱部位を局在化させることにより、体内留置具とガイドワイヤーとを分離する際、体内留置具の加熱による生体組織への侵襲を起こすことなく、容易に体内留置具とガイドワイヤーとを分離することができ、上記した従来の問題を一挙に解決できることを見出し、さらに検討を重ねて本発明を完成させた。 The present inventors have made intensive studies to achieve the above object, a connecting member between the intracorporeal indwelling equipment and the guide wire is a shape memory alloy, the heating site by the high-frequency current is provided an electrically insulating member at one end of said connecting member the by localized, when separating the guide wire intracorporeal indwelling equipment, without causing invasion into living tissue by heating the intracorporeal indwelling equipment, readily be separated and intracorporeal indwelling equipment and guide wire can, it can be solved at a stroke the conventional problems described above, and completed the present invention by overlapping a further study.

すなわち、本発明は、 That is, the present invention is,
〔1〕 導電性の線状部材の先端部に電気絶縁部材および接続部材を介して体内留置具が接続されてなり、接続部材が形状記憶合金からなり、線状部材に高周波電流が供給されると接続部材が熱されて変形し、該変形によって体内留置具が切り離されるように構成されたことを特徴とする医療用ワイヤー、 (1) the distal end of a conductive linear member through an electric insulating member and the connecting member, which are connected together by the intracorporeal indwelling equipment, connecting member is a shape memory alloy, the high-frequency current is supplied to the linear member medical wire connecting member is deformed heated, characterized in that it is configured to intracorporeal indwelling equipment is disconnected by the deformation and,
〔2〕 導電性の線状部材の先端部に、順に接続部材、電気絶縁部材および体内留置具が接続されてなることを特徴とする前記〔1〕記載の医療用ワイヤー、 [2] the distal end of a conductive linear member, connected sequentially member, the electrically insulating member and the intracorporeal indwelling equipment is characterized by comprising connected (1) medical wire according,
〔3〕 導電性の線状部材の先端部に、順に電気絶縁部材、接続部材および体内留置具が接続されてなることを特徴とする前記〔1〕記載の医療用ワイヤー、 [3] the tip of the conductive linear member, in turn electrically insulating member, connecting member and the intracorporeal indwelling equipment is characterized by comprising connected (1) medical wire according,
〔4〕 電気絶縁部材が有機高分子樹脂またはセラミックスからなることを特徴とする前記〔1〕〜〔3〕のいずれかに記載の医療用ワイヤー、 [4] The medical wire according to any one of [1] to [3] that the electrically insulating member is characterized by comprising an organic polymer resin, or ceramics,
〔5〕 体内留置具が血管内留置具である前記〔1〕〜〔4〕のいずれかに記載の医療用ワイヤー、 [5] The medical wire according to any one of the intracorporeal indwelling equipment is intravascular, indwelling instrument (1) to (4),
〔6〕 血管内留置具が二次コイルである前記〔5〕記載の医療用ワイヤー、 [6] the intravascular indwelling device is a secondary coil (5) medical wire according,
〔7〕 動脈瘤、動静脈奇形、動静脈瘻または腫瘍の治療用である前記〔1〕〜〔6〕のいずれかに記載の医療用ワイヤー、 [7] aneurysm, medical wire according to any one of arteriovenous malformations, wherein is for the treatment of arteriovenous fistula or tumor [1] to [6],
〔8〕 前記〔1〕〜〔7〕のいずれかに記載の医療用ワイヤーとカテーテルとのセット、および 〔9〕 前記〔1〕〜〔7〕のいずれかに記載の医療用ワイヤーを生体内に導入し、ついで高周波電流を医療用ワイヤーの導電性の線状部材に供給することにより、医療用ワイヤーの接続部材が熱されて変形し、該変形によって体内留置具を切り離すことを特徴とする体内留置具の切り離し方法、 [8] the [1] to set the medical wire and catheter as claimed in any one of [7], and [9] the [1] to medical wire through the living body according to any one of [7] introduced into, and then by supplying a high-frequency current to the linear electrically conductive member of the medical wire, deformed connecting member is heated in medical wire, characterized by disconnecting the intracorporeal indwelling equipment by deformation detach method of the body indwelling equipment,
に関する。 On.

本発明の医療用ガイドワイヤーは、体内留置具の直接加熱による生体組織への侵襲がなく、極めて容易にかつ短時間で体内留置具とガイドワイヤーとを分離することができるため、医者や患者に精神的、肉体的負担を少なくすることができる。 The medical guidewire of the present invention, there is no invasion of the living body tissue by direct heating of the intracorporeal indwelling equipment, it is possible to separate the indwelling instrument and the guide wire in a very easily and quickly, the doctors and patients mental, it is possible to reduce the physical burden.

本発明の医療用ワイヤーは、導電性の線状部材の先端部に電気絶縁部材および接続部材を介して体内留置具が接続されてなり、接続部材が形状記憶合金からなり、線状部材に高周波電流が供給されると接続部材が熱されて変形し、該変形によって体内留置具が切り離されるように構成されたことを特徴とする。 Medical wire of the invention will be connected intracorporeal indwelling equipment via an electrically insulating member and the connecting member to the distal end portion of the conductive linear member, the connection member is made of a shape memory alloy, the high frequency to the linear member current is deformed by heated connection members to be supplied, characterized in that it is configured to intracorporeal indwelling equipment is disconnected by the deformation.

(線状部材) (Linear members)
本発明で使用される線状部材は、導電性の線状部材であれば特に限定されず、公知のものであってよい。 Linear member used in the present invention, if the linear electrically conductive member is not particularly limited, and may be a known. このような線状部材の例としては、例えば金属ワイヤー、金属で被覆された線状物などが挙げられ、これらのワイヤーや線状物を絶縁性の樹脂で被覆したものも線状部材として用いてよい。 Examples of such linear member, for example, a metal wire, such as coated linear material is mentioned metals, also used as a line-shaped member of these wires or linear material which is coated with an insulating resin it may be. また、これらの線状部材に含まれる金属としては、例えばステンレス鋼、白金、銀、銅、金、マグネシウム、チタン、アルミニウム、ニッケル、これらの合金などが挙げられる。 The metal contained in these linear members, for example, stainless steel, platinum, silver, copper, gold, magnesium, titanium, aluminum, nickel, and alloys thereof. 線状部材の外径は、本発明の目的を阻害しない限り特に限定されないが、例えば0.01〜2.0mmである。 The outer diameter of the linear member is not particularly limited as long as it does not inhibit the object of the present invention, for example, 0.01 to 2.0 mm. 線状部材の長さは、目的に応じて種々の長さに設定されるので特に限定されないが、例えば0.1〜1.8mである。 The length of the linear member is not particularly limited because it is set to various lengths depending on the purpose, for example, 0.1~1.8M.

(電気絶縁部材) (Electrically insulating member)
本発明で使用される電気絶縁部材は、電気絶縁性を有していれば特に限定されず、生体に悪影響を与えないものが好ましい。 Electrically insulating member used in the present invention is not particularly limited as long as it has an electrically insulating property, it is preferable not to adversely affect the living body. 電気絶縁部材の形状や寸法等は本発明の目的を阻害しない限り特に限定されず、接続部材やワイヤーの構成などによって適宜に選択される。 Electrical shape and dimensions of the insulating member is not particularly limited as long as it does not inhibit the object of the present invention is appropriately selected in depending on the connecting member and the wire configuration. 電気絶縁部材としては、例えば有機材料、無機材料などが挙げられる。 The electrically insulating member, such as organic materials, inorganic materials. 有機材料の種類としては、例えば有機高分子樹脂などが挙げられ、有機高分子樹脂としては、例えば熱可塑性樹脂や熱硬化性樹脂などが挙げられる。 The types of organic materials, such as organic polymer resin, and examples of the organic polymer resin, such as thermoplastic resins and thermosetting resins. 無機材料の種類としては、ガラスやセラミックスなどが挙げられる。 The type of the inorganic materials include glass or ceramics.

熱可塑性樹脂としては、例えば、ポリエチレンテレフタレート(PET)樹脂等のポリエステル系樹脂や、ポリエチレン(PE)樹脂、ポリプロピレン(PP)樹脂等のポリオレフィン系樹脂、スチレン系樹脂、ポリアミド(PA)系樹脂、ポリカーボネート(PC)樹脂、ポリメチルメタクリレート(PMMA)樹脂、ポリ塩化ビニル(PVC)樹脂、熱可塑性エラストマーなどが挙げられる。 As the thermoplastic resin, for example, polyester resins such as polyethylene terephthalate (PET) resin, polyethylene (PE) resin, polypropylene (PP) a polyolefin resin such as a resin, styrene resin, polyamide (PA) resin, polycarbonate (PC) resin, polymethyl methacrylate (PMMA) resin, polyvinyl chloride (PVC) resins, and thermoplastic elastomers.
熱硬化性樹脂としては、例えば、フェノール樹脂、エポキシ樹脂、メラミン樹脂、ポリイミド樹脂、不飽和ポリエステル樹脂などが挙げられる。 As the thermosetting resin, for example, phenol resins, epoxy resins, melamine resins, polyimide resins, and unsaturated polyester resin.

セラミックスとしては、例えば、酸化アルミニウム、窒化アルミニウム、酸化ケイ素 、窒化ケイ素、酸化ジルコン、窒化ボロンなどが挙げられる。 The ceramic, for example, aluminum oxide, aluminum nitride, silicon oxide, silicon nitride, zirconium oxide, such as boron nitride. ガラスとしては、石英ガラス、ソーダガラス、ホウケイ酸ガラス、鉛ガラスなどが挙げられる。 As the glass, quartz glass, soda glass, borosilicate glass, and lead glass.
電気絶縁部材の形状の具体例としては、例えば図1〜5に示す電気絶縁部材4などが挙げられる。 Specific examples of the shape of the electrically insulating member, and the like electrically insulating member 4 shown in FIGS. 1-5, for example.

(接続部材) (Connecting member)
本発明で使用される接続部材は、形状記憶合金からなり、導電性の線状部材に高周波電流が供給されると接続部材が熱されて変形し、該変形によって体内留置具が切り離されるように構成されていれば特に限定されない。 Connecting member used in the present invention comprises a shape memory alloy, the high-frequency current is deformed by heated the connecting member to be supplied to the linear electrically conductive member, as intracorporeal indwelling equipment is disconnected by the deformation It not particularly limited as long as it is configured. また、接続部は、体内留置具とともに電気絶縁部材が切り離されるように構成されていてもよい。 The connecting portion may be configured such that the electrical insulating member is separated together with the in-vivo indwelling equipment. 形状記憶合金としては、例えばNi−Ti系合金、Au−Cd系合金、Cu−Al−Ni系合金、Cu−Au−Zn系合金、Cu−Zn−X(XはSi、Sn、AlまたはGa)系合金、Ni−Al系合金、およびFe−Pt系合金などが挙げられる。 As the shape memory alloy, for example, Ni-Ti-based alloy, Au-Cd alloy, Cu-Al-Ni alloy, Cu-Au-Zn alloy, Cu-Zn-X (X is Si, Sn, Al or Ga ) based alloys, Ni-Al based alloy, and Fe-Pt-based alloy. これら形状記憶合金の変態点は特に限定されないが、生体内で用いることを考慮して40〜50℃程度が好ましい。 Transformation point of the shape memory alloy is not particularly limited, considering the use in vivo is preferably about 40 to 50 ° C.. 接続部材の形状の具体例としては、例えば図1〜5に示す接続部材3などが挙げられる。 Specific examples of the shape of the connecting member, and the like connecting member 3 shown in FIGS. 1-5, for example.

(体内留置具) (Body indwelling equipment)
体内留置具は、本発明の目的を阻害しない限り特に限定されず、公知のものであってよく、これらは用途等によって適宜に選択される。 Intracorporeal indwelling equipment the purpose without particular limitation so long as it does not inhibit the present invention may be a known, they are appropriately selected depending on the application or the like. 体内留置具としては、例えば血管内留置具などが挙げられ、より具体的には例えば血栓形成部材などが挙げられる。 The intracorporeal indwelling equipment includes, for example, and intravascular indwelling device, can be mentioned, for example, thrombus formation member more specifically. このような体内留置具の好ましい例としては、例えばコイル状物などが挙げられ、より好ましい例としては、二次コイルが挙げられる。 As the preferred examples of such intracorporeal indwelling equipment, such as a coil-like material. Examples of more preferred examples include a secondary coil. 金属細線を螺旋状に巻き回してなるのが一次コイルであり、これをさらに、所定の形に巻いたものが二次コイルである。 A primary coil that formed by winding a thin metal wire spirally, which further those wound in a predetermined form is a secondary coil. 体内留置具の材質としては、生体に害を与えることなく、また、X線不透過性を有することが好ましく、好適な例としては、金、白金、それらの合金等が挙げられる。 As the material of the intracorporeal indwelling equipment, without harming the living body also preferably has a X-ray opacity, suitable examples are gold, platinum, alloys thereof.

(製造方法) (Production method)
本発明の医療用ワイヤーは、導電性の線状部材の先端部に、電気絶縁部材、接続部材および体内留置具を、常法に従い接続することにより製造される。 Medical wire of the present invention, the tip portion of the conductive linear member, an electrically insulating member, the connecting member and the intracorporeal indwelling equipment is manufactured by connecting a conventional method. 接続手段は、本発明の目的を阻害しない限り特に限定されず、公知の手段であってよい。 Connection means is not particularly limited as long as it does not inhibit the object of the present invention may be a known means. 接続手段の例としては、例えば、接着剤による接着方法、溶接による方法、物理的連結による方法などの公知の接続手段などが挙げられる。 Examples of connection means, for example, a bonding method by an adhesive, the method according to the welding, and the like known connection means such as a method by physical connection.
また、本発明の医療用ワイヤーは、前記の導電性の線状部材の先端部に、前記電気絶縁部材および前記接続部材を介して前記体内留置具が接続されてなるものであるが、前記電気絶縁部材および前記接続部材の接続順序は本発明の目的を阻害しない限り特に限定されず、導電性の線状部材の先端部に、順に電気絶縁部材、接続部材および体内留置具が接続されていてもよいし、順に接続部材、電気絶縁部材および体内留置具が接続されていてもよい。 The medical wire according to the present invention, the distal end portion of the conductive linear member, but the intracorporeal indwelling equipment via the electrically insulating member and the connecting member is made is connected, the electrical connection order of the insulating member and the connecting member is not particularly limited as long as it does not inhibit the object of the present invention, the tip portion of the conductive linear member, in turn electrically insulating member, connecting members and intracorporeal indwelling equipment is not connected it may be, connected in the forward member, the electrically insulating member and the intracorporeal indwelling equipment may be connected. 前者の場合には、電気絶縁部材の存在によって、体内留置具ではなく、導電性の線状部材の先端部周囲の体液または組織にて高周波電流による熱が生じ、その熱が接続部材の形状記憶合金へと伝わり、形状記憶合金の変態点以上の温度になると、形状記憶合金の形状変化が起こり、体内留置具が切り離される。 In the former case, the presence of the electrically insulating member, rather than the intracorporeal indwelling equipment, heat generated by the high-frequency current of a conductive linear member of the tip surrounding body fluids or tissues, the shape memory of the heat connecting member transmitted to the alloy, at a temperature above the transformation point of the shape memory alloy, the shape change of the shape memory alloy occurs, intracorporeal indwelling equipment is disconnected. 後者の場合には、電気絶縁部材の存在によって、体内留置具ではなく、接続部材周囲の体液または組織にて高周波電流による熱が生じ、その熱が接続部材の形状記憶合金の変態点以上になると形状記憶合金が変形し、体内留置具が切り離される。 In the latter case, the presence of the electrically insulating member, rather than the intracorporeal indwelling equipment, heat generated by the high-frequency current at a connection member surrounding body fluid or tissue, if the heat is lower than the transformation point of the shape memory alloy of the connecting member the shape memory alloy is deformed, intracorporeal indwelling equipment is disconnected.

(用途) (Applications)
本発明の医療用ワイヤーは、血管内治療に用いられ、特に動脈瘤、動静脈奇形、動静脈瘻または腫瘍の治療に用いられる。 Medical wire of the present invention is used in endovascular treatment, in particular aneurysms, arteriovenous malformations, used in the treatment of arteriovenous fistula or tumor. 例えば、本発明の医療用ワイヤーを生体内に導入し、ついで高周波電流を医療用ワイヤーの導電性の線状部材に供給することにより、医療用ワイヤーの接続部材を熱して変形させ、該変形によって体内留置具を切り離すことにより、前記治療が行われ得る。 For example, the medical wire of the present invention is introduced into a living body, followed by supplying a high-frequency current to the linear electrically conductive member of the medical wire is deformed by heating the connecting member of the medical wire, by deformation by disconnecting the intracorporeal indwelling equipment, the treatment may be performed.

より具体的に説明すると、本発明の医療用ワイヤーは、通常、カテーテルとともに用いられ、カテーテルを介して生体内に導入される。 More specifically, the medical wire of the present invention is usually used with a catheter, it is introduced into the body through a catheter. 例えば、図6に示すように、カテーテル20を常法に従い生体内に挿入し、体内留置具2を留置すべき個所、この例では脳動脈瘤の個所Pに到達させる。 For example, as shown in FIG. 6, inserted into a living body according to a conventional method catheter 20, points should deploy the intracorporeal indwelling equipment 2, in this example to reach the point P of the cerebral aneurysm. 図6中の符号21は、カテーテル20の手元操作部である。 Reference numeral 21 in FIG. 6 is a hand operation portion of the catheter 20. カテーテル20としては、例えばマイクロカテーテルなどの公知のカテーテルが挙げられる。 The catheter 20, include known catheters, such as for example microcatheter.

本発明の医療用ワイヤーを、体内留置具2を先頭として、手元操作部21からカテーテル20内に挿入するとき、体内留置具2が二次コイルである場合、該二次コイルは、カテーテル20に沿って略直線状に伸びた状態でカテーテル20内を移動する。 The medical wire according to the present invention, as top intracorporeal indwelling equipment 2, when inserted from the operation portion 21 to the catheter 20, if intracorporeal indwelling equipment 2 is a secondary coil, the secondary coil, the catheter 20 along move within catheter 20 in a state extending substantially linearly. そしてカテーテル20の先端開口から、医療用ワイヤーの体内留置具2を外部に突出させ、接続部材3がカテーテル20の先端開口部に位置された状態とする。 And from the tip end opening of the catheter 20, the intracorporeal indwelling equipment 2 of the medical wire is protruded to the outside, connecting member 3 is in a state of being positioned at the front end opening of the catheter 20. これにより、体内留置具2は、その弾性による復元力で、元の二次コイル体となり、血栓形成部材として作用することができる。 Thus, intracorporeal indwelling equipment 2, the restoring force by its elasticity, becomes a source of the secondary coil body, it can act as a thrombogenic member.

そして、図6に示すように、生体22の適宜の皮膚面にアース電極(対極板)23を装着した上、導電性の線状部材1の末端部とアース電極23に高周波電源装置24を接続し、高周波電流を導電性の線状部材1に供給する。 Then, as shown in FIG. 6, on which is mounted an appropriate ground electrode (counter electrode plate) 23 to the skin surface of the living body 22, connects the high-frequency power supply 24 to the distal end and the ground electrode 23 of the linear member 1 of the conductive and, supplying a high-frequency current to the linear member 1 conductive. その結果、接続部材3の周囲が熱されるとともに、電気絶縁部材4によって体内留置具2への高周波電流の伝達が遮断されて体内留置具2からの熱発生が起きない。 As a result, the surrounding is heated connecting member 3, by an electrically insulating member 4 is cut off the transmission of the high-frequency current to the intracorporeal indwelling equipment 2 heat generated from the intracorporeal indwelling equipment 2 does not occur. このことにより、体内留置具周辺の血液や生体組織に熱的侵襲を起こすことなく、接続部材3が変形し、体内留置具2が導電性の線状部材1から切り離され、体内留置具2の留置が達成される。 Thus, without causing the thermal invasive blood and body tissue surrounding intracorporeal indwelling equipment, connecting member 3 is deformed, intracorporeal indwelling equipment 2 is disconnected from the linear member 1 conductivity, of intracorporeal indwelling equipment 2 placement is achieved.
高周波電流は、本発明の目的を阻害しない限り特に限定されず、常法により導電性の線状部材に供給される。 High frequency current is not particularly limited as long as it does not inhibit the object of the present invention, it is supplied to the linear electrically conductive member in a conventional manner. このような高周波電流としては、例えば、3500Hz以上の高周波電流が挙げられ、とりわけ100kHz〜1MHzの高周波電流が好ましい。 Such high frequency current, for example, include more high-frequency current 3500 Hz, particularly 100kHz~1MHz of the high-frequency current is preferred. また、高周波電流の供給量は、形状記憶合金の変態点以上の温度を生ぜしめるに充分な量であれば特に限定されない。 Further, the supply amount of the high-frequency current is not particularly limited as long as it is an amount sufficient to give rise to a temperature above the transformation point of the shape memory alloy. 例えば、高周波電源装置から線状部材に供給される電力は、本発明の目的を阻害しない限り特に限定されないが、好ましくは、0.1〜20Wである。 For example, the power supplied to the linear member from the high-frequency power supply is not particularly limited as long as it does not inhibit the object of the present invention, preferably 0.1 to 20.

以下、図面を用いて本発明の実施例を説明するが、本発明はこれら実施例に限定されるものではない。 EXAMPLES The following explains Examples of the present invention with reference to the drawings, the present invention is not limited to these examples.

図1を用いて実施例1を説明する。 Example 1 will be described with reference to FIG. 図1(a)に示される本発明の医療用ワイヤーは、常法に従い、導電性の線状部材1、接続部材3、電気絶縁部材4および体内留置具2を接続することにより製造される。 Medical wire of the present invention shown in FIGS. 1 (a) is carried out according to a conventional method, a linear member 1 of the conductive connecting member 3, is produced by connecting the electrically insulating member 4 and the intracorporeal indwelling equipment 2. 体内留置具2は二次コイルであり、接続部材3は形状記憶合金からなる押しバネである。 Intracorporeal indwelling equipment 2 is the secondary coil, the connecting member 3 is a compression spring made of shape memory alloy. また、電気絶縁部材4は接続部材3の金属製筐体に嵌合されていて、この嵌合によって接続部材3と電気絶縁部材4とが接続されている。 Furthermore, the electrically insulating member 4 is connected is fitted to the metal housing member 3, and the connecting member 3 and the electrically insulating member 4 are connected by the fitting.

導電性の線状部材1に高周波電流を供給することにより、導電性の線状部材1と接続している筐体周囲の体液または組織が熱される。 By supplying a high-frequency current to the linear member 1 of electrically conductive fluid or tissue of the housing around which is connected to the linear member 1 of conductivity it is heated. 接続部材3は形状記憶合金からなるので、高周波電流によって熱せられた周囲からの熱により接続部材3の形状記憶合金は形状変化を引き起こす。 Since the connection member 3 made of a shape memory alloy, heat by connecting member 3 of the shape memory alloy from the surroundings that has been heated by the high frequency current causes a change in shape. この形状変化によって、図1(b)に示されるように、接続部材3の押しバネが伸び、接続部材3の筐体に嵌合されている電気絶縁部材4が、接続部材の筐体外部へ完全に押し出され、電気絶縁部材4および体内留置具2は、導電性の線状部材1および接続部材3と切り離される。 This shape change, as shown in FIG. 1 (b), the connecting member 3 of the push spring is extended, the electrical insulating member 4 that is fitted to the housing of the connecting member 3, the housing outside of the connecting member completely extruded, electrically insulating member 4 and the intracorporeal indwelling equipment 2 is disconnected from the linear member 1 and the connecting member 3 of the conductivity. このようにすることにより、体内留置具2へ高周波電流が流れないため、体内留置具周囲の組織は加熱されず、体内留置具周辺の生体組織に熱的侵襲を与えることなく、切り離し作業は容易に行われ、短時間で作業を終了させることができる。 By doing so, since no high-frequency current flows into the intracorporeal indwelling equipment 2, intracorporeal indwelling equipment surrounding tissue is not heated, without giving thermal invasive to the living tissue around the intracorporeal indwelling equipment, or disconnect easily done, it is possible to finish working in a short time.

図2を用いて実施例2を説明する。 The second embodiment will be described with reference to FIG. 図2(a)に示される本発明の医療用ワイヤーは、常法に従い、導電性の線状部材1、接続部材3、電気絶縁部材4および体内留置具2を接続することにより製造される。 Medical wire of the present invention shown in FIGS. 2 (a) is carried out according to a conventional method, a linear member 1 of the conductive connecting member 3, is produced by connecting the electrically insulating member 4 and the intracorporeal indwelling equipment 2. 体内留置具2は二次コイルであり、接続部材3は形状記憶合金からなる引きバネである。 Intracorporeal indwelling equipment 2 is the secondary coil, the connecting member 3 is a pull spring made of shape memory alloy. また、接続部材3の先端部は、電気絶縁部材4に嵌合されていて、この嵌合によって接続部材3と電気絶縁部材4とが接続されている。 The tip portion of the connecting member 3 is being fitted into an electrically insulating member 4, and the connecting member 3 and the electrically insulating member 4 are connected by the fitting.

導電性の線状部材1に高周波電流を供給することにより、導電性の線状部材1に接続している接続部材3の周囲の体液または組織が熱される。 By supplying a high-frequency current to the linear member 1 of electrically conductive fluid or tissue surrounding the connection member 3 connected to the linear member 1 of conductivity is heated. 接続部材3は形状記憶合金からなるので、高周波電流によって熱せられた周囲からの熱による接続部材3の形状記憶合金は形状変化を引き起こす。 Since the connection member 3 made of a shape memory alloy, heat from the shape memory alloy of the connecting member 3 from the surroundings that has been heated by the high frequency current causes a change in shape. この形状変化によって、図2(b)に示されるように、接続部材3の引きバネが縮み、電気絶縁部材4に嵌合されている接続部材3が、接続部材の筐体内部へ完全に収納され、電気絶縁部材4および体内留置具2は、導電性の線状部材1および接続部材3と切り離される。 This shape change, as shown in FIG. 2 (b), the connecting member 3 of the pull spring is contracted, connecting member 3 is fitted into an electrically insulating member 4 is completely accommodated into the housing interior of the connecting member is an electrically insulating member 4 and the intracorporeal indwelling equipment 2 is disconnected from the linear member 1 and the connecting member 3 of the conductivity. このようにすることにより、体内留置具2へ高周波電流が流れないため体内留置具周囲の組織は加熱されず、体内留置具周辺の生体組織に熱的侵襲を与えることなく、切り離し作業は容易に行われ、短時間で作業を終了させることができる。 In this way, the tissue surrounding intracorporeal indwelling equipment since no high-frequency current flows into the intracorporeal indwelling equipment 2 is not heated, without giving thermal invasive to the living tissue around the intracorporeal indwelling equipment, or disconnect easily done, it is possible to finish working in a short time.

図3を用いて実施例3を説明する。 The third embodiment will be described with reference to FIG. 図3(a)に示される本発明の医療用ワイヤーは、常法に従い、導電性の線状部材1、接続部材3、電気絶縁部材4および体内留置具2を接続することにより製造される。 Medical wire of the present invention shown in FIGS. 3 (a) is carried out according to a conventional method, a linear member 1 of the conductive connecting member 3, is produced by connecting the electrically insulating member 4 and the intracorporeal indwelling equipment 2. 体内留置具2は二次コイルであり、接続部材3は形状記憶合金からなり、電気絶縁部材4の球状の先端部が接続部材3に抱持されている。 Intracorporeal indwelling equipment 2 is the secondary coil, the connecting member 3 is made of a shape memory alloy, the distal end portion of the spherical electrically insulating member 4 is embracing the connecting member 3.

導電性の線状部材1に高周波電流を供給することにより、導電性の線状部材1と接続している接続部材3の周囲の体液または組織が熱される。 By supplying a high-frequency current to the linear member 1 of electrically conductive fluid or tissue surrounding the connecting member 3 is connected to the linear member 1 of conductivity is heated. 接続部材3は形状記憶合金からなるので、高周波電流によって熱せられた周囲からの熱により接続部材3の形状記憶合金は形状変化を引き起こす。 Since the connection member 3 made of a shape memory alloy, heat by connecting member 3 of the shape memory alloy from the surroundings that has been heated by the high frequency current causes a change in shape. この形状変化によって、図3(b)に示されるように、接続部材3が電気絶縁部材4を抱持できなくなり、電気絶縁部材4および体内留置具2は、導電性の線状部材1および接続部材3と切り離される。 This shape change, as shown in FIG. 3 (b), the connecting member 3 will not be able to embrace electrically insulating member 4, an electrically insulating member 4 and the intracorporeal indwelling equipment 2, a conductive linear member 1 and the connection It is separated from the member 3. このようにすることにより、体内留置具2へ高周波電流が流れないため体内留置具周囲の組織は加熱されず、体内留置具周辺の生体組織に熱的侵襲を与えることなく、切り離し作業は容易に行われ、短時間で作業を終了させることができる。 In this way, the tissue surrounding intracorporeal indwelling equipment since no high-frequency current flows into the intracorporeal indwelling equipment 2 is not heated, without giving thermal invasive to the living tissue around the intracorporeal indwelling equipment, or disconnect easily done, it is possible to finish working in a short time.

図4を用いて実施例4を説明する。 The fourth embodiment will be described with reference to FIG. 図4(a)に示される本発明の医療用ワイヤーは、常法に従い、導電性の線状部材1、接続部材3、電気絶縁部材4および体内留置具2を接続することにより製造される。 Medical wire of the present invention shown in FIGS. 4 (a) is carried out according to a conventional method, a linear member 1 of the conductive connecting member 3, is produced by connecting the electrically insulating member 4 and the intracorporeal indwelling equipment 2. 体内留置具2は二次コイルであり、接続部材3は形状記憶合金からなり、電気絶縁部材4はネジ構造体である。 Intracorporeal indwelling equipment 2 is the secondary coil, the connecting member 3 made of a shape memory alloy, an electrically insulating member 4 is threaded structure. また、接続部材3は、電気絶縁部材4に巻回されていて、係止されている。 The connecting member 3 have been turned electrically insulating member 4 wound is locked. なお、このときの接続部材3の形状は螺旋状である。 The shape of the connecting member 3 at this time is helical.

導電性の線状部材1に高周波電流を供給することにより、導電性の線状部材1と接続している接続部材3の周囲の体液または組織が熱される。 By supplying a high-frequency current to the linear member 1 of electrically conductive fluid or tissue surrounding the connecting member 3 is connected to the linear member 1 of conductivity is heated. 接続部材3は形状記憶合金からなるので、高周波電流によって熱せられた周囲からの熱により接続部材3の形状記憶合金は形状変化を引き起こす。 Since the connection member 3 made of a shape memory alloy, heat by connecting member 3 of the shape memory alloy from the surroundings that has been heated by the high frequency current causes a change in shape. この形状変化によって、接続部材3の形状が螺旋状から直線状または略直線状となり、図4(b)に示されるように、接続部材3は電気絶縁部材4を巻回できなくなり、電気絶縁部材4および体内留置具2は、導電性の線状部材1および接続部材3と切り離される。 This shape change, shape of the connecting member 3 is a straight or substantially straight from the spiral, as shown in FIG. 4 (b), connecting member 3 can no longer wound an electrical insulating member 4, an electrically insulating member 4 and intracorporeal indwelling equipment 2 is disconnected from the linear member 1 and the connecting member 3 of the conductivity. このようにすることにより、体内留置具2へ高周波電流が流れないため体内留置具周囲の組織は加熱されず、体内留置具周辺の生体組織に熱的侵襲を与えることなく、切り離し作業は容易に行われ、短時間で作業を終了させることができる。 In this way, the tissue surrounding intracorporeal indwelling equipment since no high-frequency current flows into the intracorporeal indwelling equipment 2 is not heated, without giving thermal invasive to the living tissue around the intracorporeal indwelling equipment, or disconnect easily done, it is possible to finish working in a short time.

図5を用いて実施例5を説明する。 Example 5 will be described with reference to FIG. 図5(a)に示される本発明の医療用ワイヤーは、常法に従い、導電性の線状部材1、電気絶縁部材4、接続部材3および体内留置具2を接続することにより製造される。 Medical wire of the present invention shown in FIGS. 5 (a) is carried out according to a conventional method, a linear member 1 of the conductive, electrically insulating member 4 is manufactured by connecting the connecting member 3 and the intracorporeal indwelling equipment 2. 体内留置具2は二次コイルであり、接続部材3は形状記憶合金からなり、体内留置具2の端部が、接続部材3によって挟持されている。 Intracorporeal indwelling equipment 2 is the secondary coil, the connecting member 3 is made of a shape memory alloy, the end of the intracorporeal indwelling equipment 2 is sandwiched by the connecting member 3.

導電性の線状部材1に高周波電流を供給することにより、導電性の線状部材1と接続している接続部材3の周囲の体液または組織が熱される。 By supplying a high-frequency current to the linear member 1 of electrically conductive fluid or tissue surrounding the connecting member 3 is connected to the linear member 1 of conductivity is heated. 接続部材3は形状記憶合金からなるので、高周波電流によって熱せられた周囲からの熱により接続部材3の形状記憶合金は形状変化を引き起こす。 Since the connection member 3 made of a shape memory alloy, heat by connecting member 3 of the shape memory alloy from the surroundings that has been heated by the high frequency current causes a change in shape. この形状変化によって、図5(b)に示されるように、接続部材3は電気絶縁部材4を挟持できなくなり、体内留置具2は、導電性の線状部材1、電気絶縁部材4および接続部材3と切り離される。 This shape change, as shown in FIG. 5 (b), the connecting member 3 will not be able to pinch the electrical insulating member 4, intracorporeal indwelling equipment 2 is linear member 1 of the conductive, electrically insulating member 4 and the connecting member 3 to be disconnected. このようにすることにより、体内留置具2へ高周波電流が流れないため体内留置具周囲の組織は加熱されず、体内留置具周辺の生体組織に熱的侵襲を与えることなく、切り離し作業は容易に行われ、短時間で作業を終了させることができる。 In this way, the tissue surrounding intracorporeal indwelling equipment since no high-frequency current flows into the intracorporeal indwelling equipment 2 is not heated, without giving thermal invasive to the living tissue around the intracorporeal indwelling equipment, or disconnect easily done, it is possible to finish working in a short time.

本発明の医療用ワイヤーは、血管内治療に有用であり、特に動脈瘤、動静脈奇形、動静脈瘻または腫瘍の治療に有用である。 Medical wire of the present invention are useful for the endovascular treatment is particularly useful for the treatment of aneurysms, arteriovenous malformations, arteriovenous fistula or tumor.

本発明の実施例1を説明する模式図であって、(a)は、体内留置具が二次コイルであり、接続部材が形状記憶合金からなる押しバネであり、電気絶縁部材が接続部材の筐体に嵌合されている場合の医療用ワイヤーを表し、(b)は、高周波電流によって熱せられた接続部材の形状記憶合金の形状変化によって、体内留置具および電気絶縁部材と導電性の線状部材および接続部材とが分離された状態を表す。 A schematic diagram illustrating a first embodiment of the present invention, (a) is the intracorporeal indwelling equipment is the secondary coil, the connecting member is a compression spring made of shape memory alloy, an electrically insulating member connection member It represents medical wire when being fitted to the housing, (b) is the shape change of the shape memory alloy of the connecting member which is heated by the high frequency current, intracorporeal indwelling equipment and electrical insulating member and the conductive line and Jo member and the connecting member represents a state of being separated. 本発明の実施例2を説明する模式図であって、(a)は、体内留置具が二次コイルであり、接続部材が引きバネであり、引きバネの先端部が電気絶縁部材に嵌合されている場合の医療用ワイヤーを表し、(b)は、高周波電流によって熱せられた接続部材の形状記憶合金の形状変化によって、体内留置具および電気絶縁部材と導電性の線状部材および接続部材とが分離された状態を表す。 A schematic diagram illustrating a second embodiment of the present invention, (a) is the intracorporeal indwelling equipment is the secondary coil, the connecting member is the tension spring, the fitting tip of the pull spring is on the electrically insulating member represents a medical wire if it is, (b) is the shape change of the shape memory alloy heated connecting member by high frequency current, intracorporeal indwelling equipment and electrical insulation member and the conductive linear member and the connecting member DOO represents a state of being separated. 本発明の実施例3を説明する模式図であって、(a)は、体内留置具が二次コイルであり、接続部材が形状記憶合金からなり、電気絶縁部材の球状の先端部が接続部材に抱持されている場合の医療用ワイヤーを表し、(b)は、高周波電流によって熱せられた接続部材の形状記憶合金の形状変化によって、体内留置具および電気絶縁部材と導電性の線状部材および接続部材とが分離された状態を表す。 A schematic diagram illustrating a third embodiment of the present invention, (a) is the intracorporeal indwelling equipment is the secondary coil, the connecting member is made of a shape memory alloy, the distal end portion of the spherical electrically insulating member is a connecting member represents a medical wire if it is holding in, (b) is the shape change of the shape memory alloy heated connecting member by high frequency current, intracorporeal indwelling equipment and electrical insulation member and the conductive linear member and it represents a state in which the connection and the member are separated. 本発明の実施例4を説明する模式図であって、(a)は、体内留置具が二次コイルであり、電気絶縁部材がネジであり、接続部材が形状記憶合金からなり、電気絶縁部材のネジ方向に接続部材が巻回されて接続部材と電気絶縁部材とが係止されている場合の医療用ワイヤーを表し、(b)は、高周波電流によって熱せられた接続部材の形状記憶合金の形状変化によって、体内留置具および電気絶縁部材と導電性の線状部材および接続部材とが分離された状態を表す。 A schematic diagram illustrating a fourth embodiment of the present invention, (a) shows the intracorporeal indwelling equipment is the secondary coil, an electrical insulating member is a screw, the connection member is made of a shape memory alloy, an electrically insulating member the screw direction to the connecting member represents medical wire in the case where the connection member and the electrically insulating member is wound is locked, (b), the connecting member which is heated by the high frequency current of the shape memory alloy the shape change, represents the state where the linear member and the connecting member of intracorporeal indwelling equipment and electrical insulation member and the conductive separated. 本発明の実施例5を説明する模式図であって、(a)は、体内留置具が二次コイルであり、電気絶縁部材が挟持具であり、接続部材が形状記憶合金からなり、接続部材が体内留置具を挟持している場合の医療用ワイヤーを表し、(b)は、高周波電流によって熱せられた接続部材の形状記憶合金の形状変化によって、体内留置具と、導電性の線状部材、電気絶縁部材および接続部材とが分離された状態を表す。 A schematic diagram illustrating a fifth embodiment of the present invention, (a) shows the intracorporeal indwelling equipment is the secondary coil, the electrically insulating member is a pincer, connecting member is a shape memory alloy, connecting member There represents a medical wire when sandwiching the intracorporeal indwelling equipment, (b) is the shape change of the shape memory alloy of the connecting member which is heated by the high frequency current, and intracorporeal indwelling equipment, an electrically conductive linear member represents a state in which the electrically insulating member and the connecting member is separated. 本発明の医療用ワイヤーを生体の脳動脈瘤に適用する場合を説明する模式図である。 The medical wire of the present invention is a schematic diagram for explaining the case of applying the cerebral aneurysm of the living body.

符号の説明 DESCRIPTION OF SYMBOLS

1 導電性の線状部材 2 体内留置具(二次コイル) 1 conductive linear member 2 intracorporeal indwelling equipment (secondary coil)
2a 一次コイル 3 接続部材 4 電気絶縁部材20 カテーテル21 手元操作部22 生体23 アース電極24 高周波電源装置 2a the primary coil 3 connecting member 4 electrically insulating member 20 catheter 21 the hand operation section 22 biological 23 ground electrode 24 high-frequency power supply device

Claims (9)

  1. 導電性の線状部材の先端部に電気絶縁部材および接続部材を介して体内留置具が接続されてなり、接続部材が形状記憶合金からなり、線状部材に高周波電流が供給されると接続部材が熱されて変形し、該変形によって体内留置具が切り離されるように構成されたことを特徴とする医療用ワイヤー。 It is connected to intracorporeal indwelling equipment via a conductive linear member electrically insulating member and the connecting member to the distal end portion of the connecting member is made of a shape memory alloy, connect the high frequency current to the linear member is supplied member medical wire, wherein a heated is deformed, configured to intracorporeal indwelling equipment is disconnected by the deformation.
  2. 導電性の線状部材の先端部に、順に接続部材、電気絶縁部材および体内留置具が接続されてなることを特徴とする請求項1記載の医療用ワイヤー。 The distal end portion of the conductive linear members, connecting sequentially members, medical wire according to claim 1, wherein the electrically insulating member and the intracorporeal indwelling equipment is characterized by comprising connected.
  3. 導電性の線状部材の先端部に、順に電気絶縁部材、接続部材および体内留置具が接続されてなることを特徴とする請求項1記載の医療用ワイヤー。 The distal end portion of the conductive linear member, in turn electrically insulating member, medical wire according to claim 1, wherein the connecting member and the intracorporeal indwelling equipment is characterized by comprising connected.
  4. 電気絶縁部材が有機高分子樹脂またはセラミックスからなることを特徴とする請求項1〜3のいずれかに記載の医療用ワイヤー。 Medical wire according to claim 1, the electrically insulating member is characterized by comprising an organic polymer resin or ceramics.
  5. 体内留置具が血管内留置具である請求項1〜4のいずれかに記載の医療用ワイヤー。 The medical wire according to any one of claims 1 to 4 intracorporeal indwelling equipment is intravascular, indwelling instrument.
  6. 血管内留置具が二次コイルである請求項5記載の医療用ワイヤー。 Medical wire according to claim 5, wherein the indwelling instrument is a secondary coil.
  7. 動脈瘤、動静脈奇形、動静脈瘻または腫瘍の治療用である請求項1〜6のいずれかに記載の医療用ワイヤー。 The medical wire according to any one of claims 1 to 6 aneurysm is for the treatment of arteriovenous malformations, arteriovenous fistula or tumor.
  8. 請求項1〜7のいずれかに記載の医療用ワイヤーとカテーテルとのセット。 Medical wire a set of a catheter according to claim 1.
  9. 請求項1〜7のいずれかに記載の医療用ワイヤーを生体内に導入し、ついで高周波電流を医療用ワイヤーの導電性の線状部材に供給することにより、医療用ワイヤーの接続部材を熱して変形させ、該変形によって体内留置具を切り離すことを特徴とする体内留置具の切り離し方法。 The medical wire according to any one of claims 1 to 7 is introduced into a living body, followed by supplying a high-frequency current to the linear electrically conductive member of the medical wire, by heating the connecting member of the medical wire deformed, disconnecting method of intracorporeal indwelling equipment, characterized in that disconnecting the intracorporeal indwelling equipment by deformation.
JP2004377574A 2004-12-27 2004-12-27 Medical wire Pending JP2006181088A (en)

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JP2013212374A (en) * 2012-03-30 2013-10-17 Depuy Synthes Products Llc Mechanism for detaching embolic coil by heating element and kicker
JP2017500137A (en) * 2013-12-20 2017-01-05 マイクロベンション インコーポレイテッド Catheter system

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JPH06246004A (en) * 1993-02-26 1994-09-06 Raifu Technol Kenkyusho Catheter
JPH07265431A (en) * 1994-03-31 1995-10-17 Kaneka Medics:Kk Wire for medical treatment having in-vivo indwelling member
JPH08252324A (en) * 1994-12-22 1996-10-01 Target Therapeutics Inc Method and assembly for delivery of implant
JP2000135219A (en) * 1998-10-05 2000-05-16 Cordis Corp Embolic coil separation system
JP2000229086A (en) * 1999-02-10 2000-08-22 Kaneka Medeikkusu:Kk Medical wire having endodwelling member and usage therefor
JP2001509414A (en) * 1997-07-14 2001-07-24 ボストン サイエンティフィック リミテッド Detachable vasoocclusive member using a heat-adhesive joint
JP2001513390A (en) * 1997-08-29 2001-09-04 ボストン サイエンティフィック リミテッド Quick release electrical insulation implant

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06246004A (en) * 1993-02-26 1994-09-06 Raifu Technol Kenkyusho Catheter
JPH07265431A (en) * 1994-03-31 1995-10-17 Kaneka Medics:Kk Wire for medical treatment having in-vivo indwelling member
JPH08252324A (en) * 1994-12-22 1996-10-01 Target Therapeutics Inc Method and assembly for delivery of implant
JP2001509414A (en) * 1997-07-14 2001-07-24 ボストン サイエンティフィック リミテッド Detachable vasoocclusive member using a heat-adhesive joint
JP2001513390A (en) * 1997-08-29 2001-09-04 ボストン サイエンティフィック リミテッド Quick release electrical insulation implant
JP2000135219A (en) * 1998-10-05 2000-05-16 Cordis Corp Embolic coil separation system
JP2000229086A (en) * 1999-02-10 2000-08-22 Kaneka Medeikkusu:Kk Medical wire having endodwelling member and usage therefor

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013212374A (en) * 2012-03-30 2013-10-17 Depuy Synthes Products Llc Mechanism for detaching embolic coil by heating element and kicker
JP2017500137A (en) * 2013-12-20 2017-01-05 マイクロベンション インコーポレイテッド Catheter system

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