JP2005535661A5 - - Google Patents
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- Publication number
- JP2005535661A5 JP2005535661A5 JP2004519828A JP2004519828A JP2005535661A5 JP 2005535661 A5 JP2005535661 A5 JP 2005535661A5 JP 2004519828 A JP2004519828 A JP 2004519828A JP 2004519828 A JP2004519828 A JP 2004519828A JP 2005535661 A5 JP2005535661 A5 JP 2005535661A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- microparticles
- proton pump
- pump inhibitor
- viscosity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Claims (9)
- （ａ）腸溶コーティングを被したプロトンポンプ阻害剤を含む微粒子及び
（ｂ）６．０未満のｐＨと前記微粒子を懸濁させるのに十分な粘度とを有する液体懸濁ビヒクル
を含む組成物。 - 微粒子が１００〜９００μｍの大きさである請求の範囲第１項に記載の組成物。
- 組成物が５００ｃＰ以上の粘度を有する請求の範囲第１項に記載の組成物。
- 活性成分がランソプラゾールである請求の範囲第３項に記載の組成物。
- 腸溶性プロトンポンプ阻害剤の微粒子及び６．０未満のｐＨと前記微粒子を懸濁させるのに十分な粘度とを有する液体懸濁ビヒクルを含む組成物を患者に投与することを含む胃腸疾患患者の治療方法。
- ａ）腸溶コーティングを被したプロトンポンプ阻害剤を含む微粒子を収容した第１容器及びｂ）液体を収容した第２容器を含み、前記第１または第２容器が更に酸性賦形剤を含み、第１及び第２容器の内容物を混合して生ずる液体が前記微粒子を懸濁させるのに十分な粘度を有するように前記第１または第２容器が更に増粘剤を含むキット。
- プロトンポンプ阻害剤がランソプラゾールである請求の範囲第６項に記載のキット。
- 液体の粘度が５００ｃＰ以上である請求の範囲第７項に記載のキット。
- 微粒子が１００〜９００μｍの大きさである請求の範囲第６項に記載のキット。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19023902A | 2002-07-03 | 2002-07-03 | |
| US10/190,239 | 2002-07-03 | ||
| PCT/US2003/020946 WO2004004690A1 (en) | 2002-07-03 | 2003-07-02 | Liquid dosage forms of proton pump inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012165900A Division JP2013028603A (ja) | 2002-07-03 | 2012-07-26 | プロトンポンプ阻害剤の液体剤形 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005535661A JP2005535661A (ja) | 2005-11-24 |
| JP2005535661A5 true JP2005535661A5 (ja) | 2006-08-10 |
| JP5148813B2 JP5148813B2 (ja) | 2013-02-20 |
Family
ID=30114048
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004519828A Expired - Fee Related JP5148813B2 (ja) | 2002-07-03 | 2003-07-02 | プロトンポンプ阻害剤の液体剤形 |
| JP2012165900A Pending JP2013028603A (ja) | 2002-07-03 | 2012-07-26 | プロトンポンプ阻害剤の液体剤形 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012165900A Pending JP2013028603A (ja) | 2002-07-03 | 2012-07-26 | プロトンポンプ阻害剤の液体剤形 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1572151A1 (ja) |
| JP (2) | JP5148813B2 (ja) |
| CA (1) | CA2490142A1 (ja) |
| MX (1) | MXPA05000301A (ja) |
| WO (1) | WO2004004690A1 (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9901551B2 (en) * | 2009-04-20 | 2018-02-27 | Ambra Bioscience Llc | Chemosensory receptor ligand-based therapies |
| AU2011317140A1 (en) | 2010-10-19 | 2013-05-30 | Elcelyx Therapeutics, Inc. | Chemosensory receptor ligand-based therapies |
| EP2768488A4 (en) * | 2011-10-19 | 2015-04-15 | Rp Scherer Technologies Llc | TWO-PHASE PHARMACEUTICAL DELIVERY SYSTEM |
| GB2535130B (en) * | 2014-09-29 | 2020-09-02 | Veriton Pharma Ltd | A Suspension |
| WO2017145146A1 (en) | 2016-02-25 | 2017-08-31 | Dexcel Pharma Technologies Ltd. | Compositions comprising proton pump inhibitors |
| GB202116644D0 (en) | 2021-11-18 | 2022-01-05 | Innovate Pharmaceuticals Ltd | Liquid composition |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9301489D0 (sv) * | 1993-04-30 | 1993-04-30 | Ab Astra | Veterinary composition |
| US5708017A (en) * | 1995-04-04 | 1998-01-13 | Merck & Co., Inc. | Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors |
| AU751066B2 (en) * | 1997-12-08 | 2002-08-08 | Nycomed Gmbh | Novel administration form comprising an acid-labile active compound |
| DE19925710C2 (de) * | 1999-06-07 | 2002-10-10 | Byk Gulden Lomberg Chem Fab | Neue Zubereitung und Darreichungsform enthaltend einen säurelabilen Protonenpumpenhemmer |
| KR20030059318A (ko) * | 2000-12-07 | 2003-07-07 | 알타나 파마 아게 | 산 불안정성 활성 성분을 포함하는 현탁액 형태의 약학 제제 |
| UA80393C2 (uk) * | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
-
2003
- 2003-07-02 MX MXPA05000301A patent/MXPA05000301A/es active IP Right Grant
- 2003-07-02 WO PCT/US2003/020946 patent/WO2004004690A1/en active Application Filing
- 2003-07-02 EP EP03763155A patent/EP1572151A1/en not_active Withdrawn
- 2003-07-02 JP JP2004519828A patent/JP5148813B2/ja not_active Expired - Fee Related
- 2003-07-02 CA CA002490142A patent/CA2490142A1/en not_active Abandoned
-
2012
- 2012-07-26 JP JP2012165900A patent/JP2013028603A/ja active Pending
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