JP2004530642A - 障害のあるケラチノサイト活性に関係する疾患を診断および処置するための中コンダクタンス型カリウムチャネルおよびモジュレーターの使用 - Google Patents

障害のあるケラチノサイト活性に関係する疾患を診断および処置するための中コンダクタンス型カリウムチャネルおよびモジュレーターの使用 Download PDF

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JP2004530642A
JP2004530642A JP2002554120A JP2002554120A JP2004530642A JP 2004530642 A JP2004530642 A JP 2004530642A JP 2002554120 A JP2002554120 A JP 2002554120A JP 2002554120 A JP2002554120 A JP 2002554120A JP 2004530642 A JP2004530642 A JP 2004530642A
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alkyl
formula
phenyl
hydrogen
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JP2004530642A5 (xx
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ゴッペルト，アンドレアス
アルツハイマー，クリスティアン
ケーゲル，ハイディ
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スウィッチ・バイオテック・アクチェンゲゼルシャフト
ルートヴィヒ−マクシミリアーンズ−ウニヴェルズィテート
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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JP2002554120A 2000-12-28 2001-12-27 障害のあるケラチノサイト活性に関係する疾患を診断および処置するための中コンダクタンス型カリウムチャネルおよびモジュレーターの使用 Pending JP2004530642A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10065475A DE10065475A1 (de) 2000-12-28 2000-12-28 Verwendung von "intermediate-conductance" Kaliumkanälen und Modulatoren zur Diagnose und Behandlung von Krankheiten mit gestörter Keratinozytenfunktion
US27745301P 2001-03-20 2001-03-20
PCT/EP2001/015317 WO2002053171A2 (de) 2000-12-28 2001-12-27 Verwendung von 'intermediate-conductance kaliumkanälen und modulatoren zur diagnose und behandlung von krankheiten mit gestörter keratinozytenaktivität

Publications (2)

Publication Number Publication Date
JP2004530642A true JP2004530642A (ja) 2004-10-07
JP2004530642A5 JP2004530642A5 (xx) 2005-12-22

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JP2002554120A Pending JP2004530642A (ja) 2000-12-28 2001-12-27 障害のあるケラチノサイト活性に関係する疾患を診断および処置するための中コンダクタンス型カリウムチャネルおよびモジュレーターの使用

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EP (1) EP1345618B1 (xx)
JP (1) JP2004530642A (xx)
AT (1) ATE291435T1 (xx)
CA (1) CA2433041A1 (xx)
WO (1) WO2002053171A2 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10250870A1 (de) * 2002-10-31 2004-05-13 Switch Biotech Ag Zusammensetzung enthaltend Aktivatoren von IK-Kaliumkanälen und Calcineurin-Antagonisten und deren Verwendung
WO2004064835A1 (en) * 2003-01-17 2004-08-05 Neurosearch A/S Use of ion channel modulating agents for treating pain
US7851431B2 (en) * 2005-07-27 2010-12-14 Prescription Dispensing Laboratories Treatment of actinic keratoses with calcium channel blockers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569935A (en) * 1983-03-17 1986-02-11 University Of Tennessee Research Corp. Topical treatment of psoriasis with imidazole antibiotics
EP0181793B1 (fr) * 1984-10-16 1988-07-27 Synthelabo Dérivés de pipéridine, leur préparation et leur application en thérapeutique
GB2273873A (en) * 1992-12-23 1994-07-06 Univ Sheffield Treatment of psoriasis
AU7733896A (en) * 1995-11-13 1997-06-05 Brandeis University Regulation of cancer-causing tyrosine kinases by potassium ion conductance
JP4052525B2 (ja) * 1996-09-11 2008-02-27 オレゴン ヘルス サイエンシーズ ユニバーシティー 低及び中間コンダクタンスのカルシウム活性化されたカリウムチャネル及びその使用
AU1224599A (en) * 1997-11-14 1999-06-07 Neurosearch A/S Chemical compounds having ion channel blocking activity for the treatment of immune dysfunction
JPH11209302A (ja) * 1998-01-21 1999-08-03 Pola Chem Ind Inc 抗掻痒剤
AU1648600A (en) * 1998-12-04 2000-06-26 Neurosearch A/S Use of isatin derivatives as ion channel activating agents
AU1549700A (en) * 1998-12-04 2000-06-26 Neurosearch A/S Ion channel modulating agents
CN1177831C (zh) * 1998-12-04 2004-12-01 神经研究公司 作为离子通道调节剂的新的苯并咪唑啉酮一、苯并噁唑酮一或苯并噻唑啉酮衍生物
JP2002533318A (ja) * 1998-12-22 2002-10-08 ニューロサーチ、アクティーゼルスカブ イオンチャネル調節剤

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WO2002053171A2 (de) 2002-07-11
EP1345618A2 (de) 2003-09-24
CA2433041A1 (en) 2002-07-11
ATE291435T1 (de) 2005-04-15
EP1345618B1 (de) 2005-03-23
WO2002053171A3 (de) 2003-03-20

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