JP2004051616A - Method for collecting extract of taiwan trachelospermum asiaticum - Google Patents

Method for collecting extract of taiwan trachelospermum asiaticum Download PDF

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Publication number
JP2004051616A
JP2004051616A JP2002241187A JP2002241187A JP2004051616A JP 2004051616 A JP2004051616 A JP 2004051616A JP 2002241187 A JP2002241187 A JP 2002241187A JP 2002241187 A JP2002241187 A JP 2002241187A JP 2004051616 A JP2004051616 A JP 2004051616A
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JP
Japan
Prior art keywords
extract
water
method
treatment
taiwan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2002241187A
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Japanese (ja)
Inventor
Sansei Nishibe
西部 三省
Original Assignee
Shimada Fumitake
島田 文武
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shimada Fumitake, 島田 文武 filed Critical Shimada Fumitake
Priority to JP2002241187A priority Critical patent/JP2004051616A/en
Publication of JP2004051616A publication Critical patent/JP2004051616A/en
Pending legal-status Critical Current

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Abstract

[Problem] To provide a method of collecting an extract useful for prevention and treatment of hay fever, atopy, menopause or lifestyle-related disease, and a method of using the same.
[Solution] An extract obtained by extracting the leaves and stems of Chinese mosquitoes with water and / or a water-soluble alcohol is used.

Description

[0001]
[Technical field to which the invention belongs]
TECHNICAL FIELD The present invention relates to a method for collecting an extract of Chinese moss, which can be used for prevention and treatment of hay fever, atopy, menopause, lifestyle-related diseases, and the like, and a method for using the same.
[0002]
[Conventional technology]
Pollinosis and atopy are symptoms that are caused by an allergic reaction and are often difficult to cure. Confirmation and removal of allergens are also performed. Drug treatment is the main, generally steroid and non-steroidal anti-inflammatory external preparation, pile histamine, anti-allergic agent and immunosuppressant, specifically, cromoglycate, tranilast, ketotifen fumarate, azelastine hydrochloride, oxatomide, Antiallergic and pile histamines such as terfenadine, epinastine hydrochloride, dienhydramine, phenothiazines, ferramins, diproheptadine hydrochloride, clemastine fumarate have been used. There is no cure that will work for everyone and is said to be absolute, and treatment will vary from person to person, especially the use of steroids, which involves various problems.
[0003]
Menopause includes endocrine and psychogenic ones, and endocrine disorders cause abnormalities in the physical function of the whole body due to reduced female hormone secretion due to female genital dysfunction during menopause As treatment, female hormones, tranquilizers, sedatives, hypnotics, etc. are used, but the symptoms vary from person to person.
[0004]
Lifestyle-related diseases referred to here are symptoms caused by long-term abnormalities in life, such as hypertension, arteriosclerosis, hyperlipidemia, diabetes, obesity, etc. The use has been made. For example, antihypertensive agents, hypoglycemic agents, hypolipidemic agents, cholesterol-lowering agents and the like.
[0005]
Taiwan Teika Kazura is an evergreen vine plant whose 6-9 g of foliage is decocted, taken or soaked, or taken as a powder. It is also used to cure arthritis, pulmonary tuberculosis, blood bleeding, bleeding wounds, wind bruises, scroscara, and bites caused by snakes, by grinding to a powder for external use, preparing and applying, and washing with soup.
[0006]
[Problems to be solved and used by the invention]
An object of the present invention is to provide a plant extract that is useful for preventing and treating hay fever, atopy, menopause and lifestyle-related diseases, and that can be used safely.
[0007]
[Embodiment of the invention]
The present inventor has conducted various studies on the Chinese moss, and found that water and / or a water-soluble alcohol extract of the stem and leaves of the plant were allergic to pollen allergy such as pollinosis and atopy, menopause, and life. The present inventors have found that the present invention is effective for the prevention and treatment of symptoms that are said to be modern diseases such as habitual diseases and are difficult to treat, and completed the present invention.
[0008]
The leaves and stems of the Chinese cabbage are dried and pulverized, and water and / or a water-soluble alcohol are added thereto. The substance obtained by concentrating the filtrate obtained by filtration under reduced pressure to dryness is used. The amount of the solvent used for the extraction is not particularly limited, but is preferably 1 to 10 times by weight based on the amount of the Chinese cabbage, the extraction temperature is heated, preferably heated under reflux, and the extraction time is appropriately determined by the heating temperature. Selected and extracted under agitation. The resulting extract is stored protected from moisture and protected from light.
[0009]
The extract is relatively stable, safe and can be formed in the form of conventionally used drugs, ie solutions, tablets, powders and ointments in a conventional manner. It is natural that the dosage differs depending on whether it is used for prophylaxis or for treatment. In general, 0.2 to 0.5 g / d for treatment and 0.05 to 0.1 g for prevention. / D is used, but the amount of use can be appropriately selected depending on the physical condition.
[0010]
[Action]
Conventionally, arctiin, trakeroside and other lignan compounds have been confirmed in the stem of Taiwan squid, and it is known that arctiin has vasodilatory and blood pressure lowering effects. The present inventor has studied in detail the components of the stem of Taiwan squid, and found that trakeroside has a calcium antagonistic action, has a clear antihypertensive action, and that the stem extract has a tracheal smooth muscle relaxing action. . Furthermore, it has been discovered that lignan compounds such as arctiin and matairesinoside are metabolized in vivo and exhibit a female hormone-like effect, and that they are useful for prevention of breast cancer, prevention and treatment of menopause, and that arctiin is an interleukin- It has also been found that the compound has an inhibitory effect and an antiallergic effect.
[0011]
In addition, the present discoverer examined the components of the leaves of the Chinese mosquito in detail, discovered that luteolin and its glycosides were present, including flavonoid components, and they showed a strong antioxidant effect, It oxidizes lipids in the living body and suppresses the generation of active oxygen that causes aging, cancer, lifestyle-related diseases and allergies, and exhibits anti-interleukin-5 inhibitory activity and xanthine oxidase inhibitory activity, thereby exhibiting anti-allergic, anti-inflammatory and analgesic effects. It was confirmed that the effect was exhibited.
[0012]
The extract of the present invention contains unidentified components in addition to the above components. It is presumed that all of these components act collectively to effectively prevent and treat hay fever, atopy, menopause and lifestyle-related diseases. Hereinafter, the present invention will be specifically described with reference to examples.
[0013]
[Example 1]
60 ml of water was added to 5 g of a dry fine powder of a mixture of leaves and stems (1: 1 by weight) of Taiwan Kadzuka, heated under reflux for 5 hours, cooled, filtered, and the filtrate was concentrated under reduced pressure to dryness. 0.2 g of an extract was obtained. As a result of analysis by liquid chromatography, it was confirmed that the extract contained flavonoids and lignans.
[0014]
[Example 2]
Ethanol (60 ml) was added to 5 g of a dry fine powder of a mixture of leaves and stems (1: 1 by weight) of Taiwan squid leaves, heated under reflux for 4 hours, cooled, filtered, and the filtrate was concentrated under reduced pressure and dried. 0.1 g of extract was obtained. The resulting extract contained flavonoids and lignans as a result of analysis.
[0015]
[Example 3]
Three years ago, 0.2 g / d of the Chinese lantern extract obtained in Example 1 was dissolved in hot water for one week, and the female Y was found to have severe menopause due to hot flashes on the face and night sweats around the neck for one week. However, the symptoms disappeared and improvement was recognized.
[0016]
[Example 4]
A male T having a systolic blood pressure of 165 and a diastolic blood pressure of 85 was dissolved in hot water for 1 week after dissolving 0.2 g / d of the extract obtained in Example 2 for drinking, and the blood pressure was measured. The blood pressure returned to a normal value, and an improvement in blood pressure was observed.
[0017]
[Example 5]
When the extract obtained in Example 1 was given to male S, who had itch, sneezing, runny nose and nasal congestion due to hay fever, at 0.2 g / d for 1 week, the symptoms were remarkably reduced.
[0018]
[The invention's effect]
INDUSTRIAL APPLICABILITY The extract of Chinese moss obtained by the present invention is easily obtained, is safe for humans, and is effective for prevention and treatment of hay fever, atby, menopause and lifestyle-related diseases.

Claims (5)

  1. A method for collecting an extract of Chinese moss, characterized by extracting Chinese moss with water and / or water-soluble alcohol
  2. 2. The collection method according to claim 1, wherein the amount of water and / or water-soluble alcohol is 1 to 10 times the weight of the Chinese cabbage.
  3. Use of the extract according to claim 1 for prevention and treatment of hay fever or atopy.
  4. Use of the extract according to claim 1 for prevention and treatment of menopause.
  5. Use of the extract according to claim 1 for prevention and treatment of lifestyle-related diseases.
JP2002241187A 2002-07-19 2002-07-19 Method for collecting extract of taiwan trachelospermum asiaticum Pending JP2004051616A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2002241187A JP2004051616A (en) 2002-07-19 2002-07-19 Method for collecting extract of taiwan trachelospermum asiaticum

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002241187A JP2004051616A (en) 2002-07-19 2002-07-19 Method for collecting extract of taiwan trachelospermum asiaticum

Publications (1)

Publication Number Publication Date
JP2004051616A true JP2004051616A (en) 2004-02-19

Family

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Family Applications (1)

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Country Status (1)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007013547A1 (en) * 2005-07-29 2007-02-01 Calpis Co., Ltd. Prophylactic/ameliorating agent for menopausal disorder and functional beverage/food
WO2008004804A1 (en) * 2006-07-03 2008-01-10 Shin-Il Pharmaceutical Co., Ltd. Trachelospermi caulis extract composition for the treatment and prevention of inflammatory diseases
JP2010516755A (en) * 2007-01-24 2010-05-20 シン−イル ファーマシューティカル カンパニー リミテッド Pharmaceutical composition for prevention and / or treatment of inflammatory diseases, comprising a mixed extract of Tsukiishi wisteria and Ichiyakuso
CN103127277A (en) * 2013-02-19 2013-06-05 青岛正大海尔制药有限公司 Medicine composition used for treating hepatitis

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007013547A1 (en) * 2005-07-29 2007-02-01 Calpis Co., Ltd. Prophylactic/ameliorating agent for menopausal disorder and functional beverage/food
JP4808715B2 (en) * 2005-07-29 2011-11-02 カルピス株式会社 Menopause prevention / amelioration agent and functional food and drink
WO2008004804A1 (en) * 2006-07-03 2008-01-10 Shin-Il Pharmaceutical Co., Ltd. Trachelospermi caulis extract composition for the treatment and prevention of inflammatory diseases
JP2009542634A (en) * 2006-07-03 2009-12-03 シン−イル ファーマシューティカル カンパニー リミテッド Pharmaceutical composition for the prevention and treatment of inflammatory diseases comprising extract
CN101484179B (en) * 2006-07-03 2011-10-12 信一制药株式会社 Trachelospermi caulis extract composition for the treatment and prevention of inflammatory diseases
EP2040726A4 (en) * 2006-07-03 2012-05-23 Shin Il Pharmaceutical Co Ltd Trachelospermi caulis extract composition for the treatment and prevention of inflammatory diseases
JP2010516755A (en) * 2007-01-24 2010-05-20 シン−イル ファーマシューティカル カンパニー リミテッド Pharmaceutical composition for prevention and / or treatment of inflammatory diseases, comprising a mixed extract of Tsukiishi wisteria and Ichiyakuso
CN103127277A (en) * 2013-02-19 2013-06-05 青岛正大海尔制药有限公司 Medicine composition used for treating hepatitis

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