JP2003517432A - プラバスタチンナトリウム含有薬剤組成物 - Google Patents
プラバスタチンナトリウム含有薬剤組成物Info
- Publication number
- JP2003517432A JP2003517432A JP2000540858A JP2000540858A JP2003517432A JP 2003517432 A JP2003517432 A JP 2003517432A JP 2000540858 A JP2000540858 A JP 2000540858A JP 2000540858 A JP2000540858 A JP 2000540858A JP 2003517432 A JP2003517432 A JP 2003517432A
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- pravastatin sodium
- cyclodextrin
- stability
- magnesium stearate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Nanotechnology (AREA)
- Obesity (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1998/11172 | 1998-03-31 | ||
KR1019980011172A KR100281521B1 (ko) | 1998-03-31 | 1998-03-31 | 프라바스타틴나트륨이 함유된 약제 조성물 |
PCT/KR1999/000157 WO1999049896A1 (en) | 1998-03-31 | 1999-03-31 | A drug composition containing sodium pravastatin |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2003517432A true JP2003517432A (ja) | 2003-05-27 |
Family
ID=19535615
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000540858A Pending JP2003517432A (ja) | 1998-03-31 | 1999-03-31 | プラバスタチンナトリウム含有薬剤組成物 |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1067967A1 (zh) |
JP (1) | JP2003517432A (zh) |
KR (1) | KR100281521B1 (zh) |
CN (1) | CN1298311A (zh) |
AU (1) | AU3057099A (zh) |
CA (1) | CA2326603A1 (zh) |
WO (1) | WO1999049896A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013147488A (ja) * | 2011-12-21 | 2013-08-01 | Taisho Pharmaceutical Co Ltd | 固形製剤 |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4658306B2 (ja) * | 2000-10-18 | 2011-03-23 | ナガセ医薬品株式会社 | 錠剤用医薬組成物 |
AU2002358468A1 (en) * | 2001-12-21 | 2003-07-15 | Rigshospitalet | Igamete recruitment and developmental competence in mammals by inhibiting the de novo sterol biosynthesis and/or promoting sterol efflux |
AU2002244881A1 (en) * | 2002-03-22 | 2003-10-08 | Ranbaxy Laboratories Limited | Controlled release drug delivery system of pravastatin |
US20060229277A1 (en) * | 2005-04-08 | 2006-10-12 | Orbus Pharma, Inc. | Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor |
WO2007016757A1 (en) * | 2005-08-05 | 2007-02-15 | Orbus Pharma Inc. | Stabilized extended release pharmeceutical compositions comprising an hmg-coa reductase inhibitor |
US7879821B2 (en) * | 2006-01-26 | 2011-02-01 | University Of Medicine And Dentistry Of New Jersey | Method for modulating inflammatory responses by altering plasma lipid levels |
BG934U1 (bg) * | 2006-12-14 | 2007-11-30 | "Софарма" Ад | Състав за твърда лекарствена форма, съдържащ правастатин |
GB0713707D0 (en) * | 2007-07-13 | 2007-08-22 | Generics Uk Ltd | Stable compositions |
CN101580466B (zh) * | 2008-05-12 | 2012-04-04 | 上海天伟生物制药有限公司 | 一种萘维太定的钠盐的制备方法 |
JP4890657B1 (ja) * | 2011-06-03 | 2012-03-07 | 小野薬品工業株式会社 | リマプロストとβ−シクロデキストリンを含有する錠剤 |
JP6088872B2 (ja) * | 2013-03-22 | 2017-03-01 | サラヤ株式会社 | ラクトン型ソホロリピッドの分解が抑制されたソホロリピッド粉末 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3223232C2 (de) * | 1982-06-22 | 1984-04-05 | Wolfgang Dipl.-Phys. Dr.-Ing. 4800 Bielefeld Lindemann | Vorschubeinrichtung an einer mit einem umlaufenden Werkzeug versehenen Maschine, wie Schäl- oder Richtmaschine, für stangenförmiges Material, wie Wellen, Draht, Rohre o.dgl. |
DD232198A1 (de) * | 1984-07-13 | 1986-01-22 | Jenapharm Veb | Verfahren zur herstellung von festen komprimaten |
US5030447A (en) * | 1988-03-31 | 1991-07-09 | E. R. Squibb & Sons, Inc. | Pharmaceutical compositions having good stability |
TW224049B (zh) * | 1991-12-31 | 1994-05-21 | Sunkyong Ind Ltd |
-
1998
- 1998-03-31 KR KR1019980011172A patent/KR100281521B1/ko not_active IP Right Cessation
-
1999
- 1999-03-31 CN CN99805551A patent/CN1298311A/zh active Pending
- 1999-03-31 AU AU30570/99A patent/AU3057099A/en not_active Abandoned
- 1999-03-31 JP JP2000540858A patent/JP2003517432A/ja active Pending
- 1999-03-31 EP EP99912138A patent/EP1067967A1/en not_active Withdrawn
- 1999-03-31 WO PCT/KR1999/000157 patent/WO1999049896A1/en not_active Application Discontinuation
- 1999-03-31 CA CA002326603A patent/CA2326603A1/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013147488A (ja) * | 2011-12-21 | 2013-08-01 | Taisho Pharmaceutical Co Ltd | 固形製剤 |
Also Published As
Publication number | Publication date |
---|---|
EP1067967A1 (en) | 2001-01-17 |
WO1999049896A1 (en) | 1999-10-07 |
CN1298311A (zh) | 2001-06-06 |
CA2326603A1 (en) | 1999-10-07 |
AU3057099A (en) | 1999-10-18 |
KR100281521B1 (ko) | 2001-02-15 |
KR19990076302A (ko) | 1999-10-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20050208 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20050705 |