JP2003501367A - 哺乳類における細胞傷害、特に抗腫瘍または抗ウイルスの治療用の組成物 - Google Patents

哺乳類における細胞傷害、特に抗腫瘍または抗ウイルスの治療用の組成物

Info

Publication number
JP2003501367A
JP2003501367A JP2001501166A JP2001501166A JP2003501367A JP 2003501367 A JP2003501367 A JP 2003501367A JP 2001501166 A JP2001501166 A JP 2001501166A JP 2001501166 A JP2001501166 A JP 2001501166A JP 2003501367 A JP2003501367 A JP 2003501367A
Authority
JP
Japan
Prior art keywords
polypeptide
nucleic acid
vector
composition
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001501166A
Other languages
English (en)
Japanese (ja)
Inventor
エチエンヌ、レギュリエ
フィリップ、エルブ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Original Assignee
Transgene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene SA filed Critical Transgene SA
Publication of JP2003501367A publication Critical patent/JP2003501367A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/195Chemokines, e.g. RANTES
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2013IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/217IFN-gamma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2001501166A 1999-06-08 2000-06-07 哺乳類における細胞傷害、特に抗腫瘍または抗ウイルスの治療用の組成物 Pending JP2003501367A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9907181 1999-06-08
FR99/07181 1999-06-08
PCT/FR2000/001559 WO2000074629A2 (fr) 1999-06-08 2000-06-07 Composition destinee a la mise en oeuvre d'un traitement cytotoxique, notamment antitumoral ou antiviral, chez un mammifere

Publications (1)

Publication Number Publication Date
JP2003501367A true JP2003501367A (ja) 2003-01-14

Family

ID=9546486

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001501166A Pending JP2003501367A (ja) 1999-06-08 2000-06-07 哺乳類における細胞傷害、特に抗腫瘍または抗ウイルスの治療用の組成物

Country Status (5)

Country Link
EP (1) EP1100916A2 (fr)
JP (1) JP2003501367A (fr)
AU (1) AU780074B2 (fr)
CA (1) CA2339900A1 (fr)
WO (1) WO2000074629A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008519596A (ja) * 2004-11-14 2008-06-12 ヴァスキュラー バイオジェニックス リミテッド 内皮細胞特異性を示すプロモーター及びそのプロモーターを使って血管形成を制御する方法
US8415318B2 (en) 2001-10-19 2013-04-09 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
US8846401B2 (en) 2000-11-17 2014-09-30 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100543036C (zh) 2002-05-06 2009-09-23 得克萨斯州大学系统董事会 递送治疗或诊断试剂的导向蛋白质

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5847794A (en) * 1992-12-09 1994-07-04 Indiana University Foundation Suppression of myeloid cells
ZA968896B (en) * 1995-10-24 1997-04-24 Smithkline Beecham Corp Method of mobilizing hematopoietic stem cells

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8835398B2 (en) 2000-11-17 2014-09-16 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
US8846401B2 (en) 2000-11-17 2014-09-30 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US8859747B2 (en) 2000-11-17 2014-10-14 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US8859745B2 (en) 2000-11-17 2014-10-14 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US8415318B2 (en) 2001-10-19 2013-04-09 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
US8916378B2 (en) 2001-10-19 2014-12-23 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulations of angiogenesis and anticancer therapy
JP2008519596A (ja) * 2004-11-14 2008-06-12 ヴァスキュラー バイオジェニックス リミテッド 内皮細胞特異性を示すプロモーター及びそのプロモーターを使って血管形成を制御する方法
JP2012010710A (ja) * 2004-11-14 2012-01-19 Vascular Biogenics Ltd 内皮細胞特異性を示すプロモーター及びそのプロモーターを使って血管形成を制御する方法

Also Published As

Publication number Publication date
CA2339900A1 (fr) 2000-12-14
EP1100916A2 (fr) 2001-05-23
AU5688300A (en) 2000-12-28
WO2000074629A3 (fr) 2001-03-22
AU780074B2 (en) 2005-02-24
WO2000074629A2 (fr) 2000-12-14

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