JP2002538132A5 - - Google Patents
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- Publication number
- JP2002538132A5 JP2002538132A5 JP2000602198A JP2000602198A JP2002538132A5 JP 2002538132 A5 JP2002538132 A5 JP 2002538132A5 JP 2000602198 A JP2000602198 A JP 2000602198A JP 2000602198 A JP2000602198 A JP 2000602198A JP 2002538132 A5 JP2002538132 A5 JP 2002538132A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- substituted
- halogen
- salt
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 20
- 229910052736 halogen Inorganic materials 0.000 claims 15
- 150000002367 halogens Chemical class 0.000 claims 15
- 150000001875 compounds Chemical class 0.000 claims 14
- 150000003839 salts Chemical class 0.000 claims 14
- 125000003545 alkoxy group Chemical group 0.000 claims 13
- 125000003118 aryl group Chemical group 0.000 claims 13
- 125000000217 alkyl group Chemical group 0.000 claims 8
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 8
- 125000001769 aryl amino group Chemical group 0.000 claims 6
- -1 pentenylene group Chemical group 0.000 claims 6
- 125000004076 pyridyl group Chemical group 0.000 claims 6
- 125000004104 aryloxy group Chemical group 0.000 claims 4
- 125000004450 alkenylene group Chemical group 0.000 claims 3
- 125000005569 butenylene group Chemical group 0.000 claims 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 3
- 125000002947 alkylene group Chemical group 0.000 claims 2
- 125000002490 anilino group Chemical group [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 125000003392 indanyl group Chemical group C1(CCC2=CC=CC=C12)* 0.000 claims 2
- MKGPZKDTSVIAGL-MRXNPFEDSA-N 4-fluoro-n-[(2r)-1,2,3,4-tetrahydronaphthalen-2-yl]benzamide Chemical compound C1=CC(F)=CC=C1C(=O)N[C@H]1CC2=CC=CC=C2CC1 MKGPZKDTSVIAGL-MRXNPFEDSA-N 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- BOFMSBVSYVESTM-UHFFFAOYSA-N n-(2,3-dihydro-1h-inden-2-yl)-4-fluorobenzamide Chemical compound C1=CC(F)=CC=C1C(=O)NC1CC2=CC=CC=C2C1 BOFMSBVSYVESTM-UHFFFAOYSA-N 0.000 claims 1
- 231100000252 nontoxic Toxicity 0.000 claims 1
- 230000003000 nontoxic effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU8912 | 1999-02-26 | ||
| AUPP8912A AUPP891299A0 (en) | 1999-02-26 | 1999-02-26 | New 6-membered cyclic compounds |
| PCT/JP2000/000601 WO2000051970A1 (en) | 1999-02-26 | 2000-02-03 | Amide compounds for the potentiation of cholinergic activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002538132A JP2002538132A (ja) | 2002-11-12 |
| JP2002538132A5 true JP2002538132A5 (https=) | 2005-07-07 |
| JP4089159B2 JP4089159B2 (ja) | 2008-05-28 |
Family
ID=3813111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000602198A Expired - Fee Related JP4089159B2 (ja) | 1999-02-26 | 2000-02-03 | コリン作用活性の強化作用を有するアミド化合物 |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1159258B1 (https=) |
| JP (1) | JP4089159B2 (https=) |
| KR (1) | KR100620406B1 (https=) |
| CN (1) | CN1170814C (https=) |
| AR (1) | AR029618A1 (https=) |
| AT (1) | ATE282022T1 (https=) |
| AU (2) | AUPP891299A0 (https=) |
| BR (1) | BR0010225A (https=) |
| CA (1) | CA2371827C (https=) |
| DE (1) | DE60015732T2 (https=) |
| DK (1) | DK1159258T3 (https=) |
| ES (1) | ES2226775T3 (https=) |
| HK (1) | HK1044934B (https=) |
| HU (1) | HUP0200116A3 (https=) |
| PT (1) | PT1159258E (https=) |
| RU (1) | RU2211215C2 (https=) |
| TR (1) | TR200102494T2 (https=) |
| TW (1) | TWI225856B (https=) |
| WO (1) | WO2000051970A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000030446A1 (en) | 1998-11-23 | 2000-06-02 | Bonnie Davis | Dosage formulations for acetylcholinesterase inhibitors |
| EE04996B1 (et) | 1998-12-24 | 2008-04-15 | Janssen Pharmaceutica N.V. | Reguleeritud vabanemisega galantamiinipreparaat, meetod selle valmistamiseks, seda sisaldav doseerimisvorm ning farmatseutiline pakend |
| TWI243164B (en) | 2001-02-13 | 2005-11-11 | Aventis Pharma Gmbh | Acylated indanyl amines and their use as pharmaceuticals |
| PE20020870A1 (es) | 2001-02-13 | 2002-11-18 | Aventis Pharma Gmbh | 6,7,8,9-tetrahidro-5h-benzocicloheptenil aminas aciladas |
| TWI241190B (en) * | 2001-02-13 | 2005-10-11 | Aventis Pharma Gmbh | 4-Fluoro-N-indan-2-yl benzamide and its use as pharmaceutical |
| PE20020856A1 (es) * | 2001-02-13 | 2002-11-11 | Aventis Pharma Gmbh | 1,2,3,4-tetrahidronaftil aminas aciladas |
| WO2003097586A1 (en) * | 2002-05-17 | 2003-11-27 | Janssen Pharmaceutica N.V. | Aminotetralin-derived urea modulators of vanilloid vr1 receptor |
| BRPI0413347A (pt) | 2003-08-06 | 2006-10-10 | Senomyx Inc | novos sabores, modificadores de sabor, agentes de sabor, realçadores de sabor, agentes de sabor e/ou realçadores umami ou doces, e utilização correspondente |
| KR101387563B1 (ko) | 2006-04-21 | 2014-04-25 | 세노믹스, 인코포레이티드 | 고효능의 조미용 향료를 포함하는 식품 조성물 및 이의 제조 방법 |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| UY32442A (es) | 2009-02-13 | 2010-09-30 | Sanofi Aventis | Nuevos indanos sustituidos, procesos para su preparacion y uso de los mismos como un medicamento |
| JP2025066196A (ja) * | 2022-03-14 | 2025-04-23 | 国立大学法人東北大学 | 認知機能改善剤 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR8287M (https=) * | 1968-12-31 | 1970-11-09 | ||
| US4797419A (en) * | 1986-11-03 | 1989-01-10 | Warner-Lambert Company | Method of treating the symptoms of senile cognitive decline employing di- or trisubstituted urea cholinergic agents |
| EP0306375A1 (fr) * | 1987-08-07 | 1989-03-08 | Synthelabo | Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique |
| IL90279A (en) * | 1988-05-24 | 1995-03-30 | American Home Prod | Piperazinyl carboxamide derivatives, their preparation and pharmaceutical com¦ositions containing them |
| GB8917687D0 (en) * | 1989-08-02 | 1989-09-20 | Fujisawa Pharmaceutical Co | Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
| RU2024507C1 (ru) * | 1991-11-18 | 1994-12-15 | Евгений Яковлевич Левитин | 5-хлор-2-пиридиламид-4-нитро-n-(карбоксиметил)антраниловой кислоты, проявляющий противовоспалительную активность |
| JPH06107544A (ja) * | 1992-09-29 | 1994-04-19 | Taisho Pharmaceut Co Ltd | コリン作動性神経不全の改善・治療薬 |
| JPH06298732A (ja) * | 1993-02-16 | 1994-10-25 | Taisho Pharmaceut Co Ltd | インドール誘導体 |
-
1999
- 1999-02-26 AU AUPP8912A patent/AUPP891299A0/en not_active Abandoned
-
2000
- 2000-02-03 AU AU23257/00A patent/AU766655B2/en not_active Ceased
- 2000-02-03 KR KR1020017010325A patent/KR100620406B1/ko not_active Expired - Fee Related
- 2000-02-03 PT PT00902080T patent/PT1159258E/pt unknown
- 2000-02-03 RU RU2001126120/04A patent/RU2211215C2/ru not_active IP Right Cessation
- 2000-02-03 HU HU0200116A patent/HUP0200116A3/hu unknown
- 2000-02-03 BR BR0010225-3A patent/BR0010225A/pt not_active Application Discontinuation
- 2000-02-03 DE DE60015732T patent/DE60015732T2/de not_active Expired - Lifetime
- 2000-02-03 CN CNB008043035A patent/CN1170814C/zh not_active Expired - Fee Related
- 2000-02-03 DK DK00902080T patent/DK1159258T3/da active
- 2000-02-03 AT AT00902080T patent/ATE282022T1/de not_active IP Right Cessation
- 2000-02-03 EP EP00902080A patent/EP1159258B1/en not_active Expired - Lifetime
- 2000-02-03 JP JP2000602198A patent/JP4089159B2/ja not_active Expired - Fee Related
- 2000-02-03 CA CA002371827A patent/CA2371827C/en not_active Expired - Fee Related
- 2000-02-03 HK HK02106646.3A patent/HK1044934B/zh not_active IP Right Cessation
- 2000-02-03 WO PCT/JP2000/000601 patent/WO2000051970A1/en not_active Ceased
- 2000-02-03 ES ES00902080T patent/ES2226775T3/es not_active Expired - Lifetime
- 2000-02-03 TR TR2001/02494T patent/TR200102494T2/xx unknown
- 2000-02-14 TW TW089102410A patent/TWI225856B/zh not_active IP Right Cessation
- 2000-02-24 AR ARP000100793A patent/AR029618A1/es unknown
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