JP2002527206A5 - - Google Patents

Download PDF

Info

Publication number
JP2002527206A5
JP2002527206A5 JP2000576829A JP2000576829A JP2002527206A5 JP 2002527206 A5 JP2002527206 A5 JP 2002527206A5 JP 2000576829 A JP2000576829 A JP 2000576829A JP 2000576829 A JP2000576829 A JP 2000576829A JP 2002527206 A5 JP2002527206 A5 JP 2002527206A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000576829A
Other languages
Japanese (ja)
Other versions
JP2002527206A (ja
JP4467799B2 (ja
Filing date
Publication date
Priority claimed from FR9813019A external-priority patent/FR2784580B1/fr
Application filed filed Critical
Publication of JP2002527206A publication Critical patent/JP2002527206A/ja
Publication of JP2002527206A5 publication Critical patent/JP2002527206A5/ja
Application granted granted Critical
Publication of JP4467799B2 publication Critical patent/JP4467799B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2000576829A 1998-10-16 1999-10-15 ポリビニルアルコール微小球、ならびにその製造方法および治療用途 Expired - Lifetime JP4467799B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9813019A FR2784580B1 (fr) 1998-10-16 1998-10-16 Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci
FR98/13019 1998-10-16
PCT/EP1999/007846 WO2000023054A1 (en) 1998-10-16 1999-10-15 Polyvinyl alcohol microspheres, and methods for making and therapeutic uses of the same

Publications (3)

Publication Number Publication Date
JP2002527206A JP2002527206A (ja) 2002-08-27
JP2002527206A5 true JP2002527206A5 (US07585860-20090908-C00150.png) 2008-06-05
JP4467799B2 JP4467799B2 (ja) 2010-05-26

Family

ID=33462605

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000576829A Expired - Lifetime JP4467799B2 (ja) 1998-10-16 1999-10-15 ポリビニルアルコール微小球、ならびにその製造方法および治療用途

Country Status (10)

Country Link
US (4) US6680046B1 (US07585860-20090908-C00150.png)
EP (1) EP1128816B1 (US07585860-20090908-C00150.png)
JP (1) JP4467799B2 (US07585860-20090908-C00150.png)
AT (1) ATE262319T1 (US07585860-20090908-C00150.png)
AU (1) AU1039600A (US07585860-20090908-C00150.png)
CA (1) CA2345205A1 (US07585860-20090908-C00150.png)
DE (1) DE69915858T2 (US07585860-20090908-C00150.png)
ES (1) ES2219072T3 (US07585860-20090908-C00150.png)
FR (1) FR2784580B1 (US07585860-20090908-C00150.png)
WO (1) WO2000023054A1 (US07585860-20090908-C00150.png)

Families Citing this family (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6660301B1 (en) 1998-03-06 2003-12-09 Biosphere Medical, Inc. Injectable microspheres for dermal augmentation and tissue bulking
FR2784580B1 (fr) 1998-10-16 2004-06-25 Biosepra Inc Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci
ATE376433T1 (de) * 1999-03-25 2007-11-15 Metabolix Inc Medizinische vorrichtungen und verwendungen von polyhydroxyalkanoatpolymeren
DE60139112D1 (de) * 2000-03-06 2009-08-13 Boston Scient Ltd Unter ultralschall sichtbare embolisierende substanzen
JP5460939B2 (ja) 2000-03-13 2014-04-02 バイオコンパティブルズ ユーケー リミテッド ヒドロゲル生物医学用製品
US6652883B2 (en) 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
US6676971B2 (en) 2000-03-13 2004-01-13 Biocure, Inc. Embolic compositions
WO2001070289A2 (en) 2000-03-20 2001-09-27 Biosphere Medical, Inc. Injectable and swellable microspheres for tissue bulking
US6436424B1 (en) 2000-03-20 2002-08-20 Biosphere Medical, Inc. Injectable and swellable microspheres for dermal augmentation
US7338657B2 (en) 2001-03-15 2008-03-04 Biosphere Medical, Inc. Injectable microspheres for tissue construction
US20030212022A1 (en) * 2001-03-23 2003-11-13 Jean-Marie Vogel Compositions and methods for gene therapy
DE01918975T1 (de) 2000-03-24 2006-04-13 Biosphere Medical, Inc., Rockland Mikrokügelchen zur aktiven Embolisierung
US20040266983A1 (en) * 2000-08-17 2004-12-30 Reeve Lorraine E Purified polyoxyalkylene block copolymers
US9080146B2 (en) * 2001-01-11 2015-07-14 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
WO2003022244A1 (en) 2001-09-12 2003-03-20 Virexx Research, Inc. Vascular occlusion solid-phase agent with immobilised platelet binding agent
US7131997B2 (en) * 2002-03-29 2006-11-07 Scimed Life Systems, Inc. Tissue treatment
US7094369B2 (en) * 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7462366B2 (en) * 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7053134B2 (en) * 2002-04-04 2006-05-30 Scimed Life Systems, Inc. Forming a chemically cross-linked particle of a desired shape and diameter
EP1511522B1 (en) 2002-06-12 2011-08-10 Boston Scientific Limited Bulking agents
US20080226723A1 (en) * 2002-07-05 2008-09-18 Celonova Biosciences, Inc. Loadable Polymeric Particles for Therapeutic Use in Erectile Dysfunction and Methods of Preparing and Using the Same
US7449236B2 (en) * 2002-08-09 2008-11-11 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US7842377B2 (en) * 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) * 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7883490B2 (en) * 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US7588825B2 (en) * 2002-10-23 2009-09-15 Boston Scientific Scimed, Inc. Embolic compositions
CA2507404A1 (en) * 2002-11-04 2004-05-21 Biosphere Medical Radioisotope-associated polymeric hydrogel microspheres and methods for producing and using the same
DE602004010492T2 (de) * 2003-02-21 2008-11-13 Biocompatibles Uk Ltd., Farnham Abgabe eines nsaid aus embolischen mitteln
CN102813967A (zh) * 2003-03-24 2012-12-12 普拉罗美德公司 利用逆向热敏聚合物的暂时栓塞
JP2004313759A (ja) * 2003-03-31 2004-11-11 Toray Ind Inc 血管塞栓材料
PT1638615E (pt) 2003-05-08 2015-02-04 Tepha Inc Fibras e tecidos médicos de polihidroxialcanoato
ES2395077T3 (es) * 2003-07-08 2013-02-08 Tepha, Inc. Matrices poli-4-hidroxibutirato para una administración prolongada de medicamentos
WO2005020825A1 (en) * 2003-08-22 2005-03-10 Tepha, Inc. Polyhydroxyalkanoate nerve regeneration devices
WO2005018600A2 (en) * 2003-08-22 2005-03-03 Cube Medical A/S Method of treating a patient suffering from a solid tumour
US7976823B2 (en) * 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US7901770B2 (en) * 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
WO2005046438A2 (en) * 2003-11-06 2005-05-26 Pluromed, Inc. Internal clamp for surgical procedures
US7736671B2 (en) * 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US20050238870A1 (en) * 2004-04-22 2005-10-27 Marcia Buiser Embolization
JP4655505B2 (ja) * 2004-04-28 2011-03-23 東レ株式会社 架橋生分解性粒子およびその製造方法
US7311861B2 (en) * 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
DE602005024967D1 (de) 2004-06-29 2011-01-05 Biocure Inc Bandscheiben-nucleus-pulposus-implantat
US20070258939A1 (en) * 2004-08-03 2007-11-08 Biocamparibles Uk Limited Drug Delivery from Embolic Agents
PT1778305E (pt) * 2004-08-03 2010-07-27 Tepha Inc Suturas de poli-hidroxialcanoato que n†o se enrolam
US20070281028A1 (en) * 2004-08-04 2007-12-06 Biocompatibles Uk Limited Drug Delivery of a Cox Inhibitor from Embolic Agents
US20210299056A9 (en) 2004-10-25 2021-09-30 Varian Medical Systems, Inc. Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
EP1804773B1 (en) 2004-10-25 2011-03-30 CeloNova BioSciences Germany GmbH Loadable polyphosphazene-comprising particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
US9114162B2 (en) 2004-10-25 2015-08-25 Celonova Biosciences, Inc. Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same
US9107850B2 (en) * 2004-10-25 2015-08-18 Celonova Biosciences, Inc. Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
US8663225B2 (en) * 2004-11-12 2014-03-04 Medtronic, Inc. Hydrogel bone void filler
US8425550B2 (en) 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
US7727555B2 (en) * 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7858183B2 (en) * 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7963287B2 (en) * 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
WO2006119968A2 (en) 2005-05-09 2006-11-16 Biosphere Medical S.A. Compositions and methods using microspheres and non-ionic contrast agents
US20070004973A1 (en) * 2005-06-15 2007-01-04 Tan Sharon M L Tissue treatment methods
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
WO2007004484A1 (ja) * 2005-07-01 2007-01-11 The Nippon Synthetic Chemical Industry Co., Ltd. 血管一時塞栓剤用pva粒子、その製造方法、および血管一時塞栓剤
US8007509B2 (en) * 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
US20070083219A1 (en) * 2005-10-12 2007-04-12 Buiser Marcia S Embolic coil introducer sheath locking mechanisms
CA2634176A1 (en) * 2005-10-26 2007-05-03 Biocure, Inc. Hydrogel spinal disc implants with swellable articles
US8152839B2 (en) * 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US20070142859A1 (en) * 2005-12-19 2007-06-21 Boston Scientific Scimed, Inc. Embolic coils
US7947368B2 (en) * 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
US7501179B2 (en) * 2005-12-21 2009-03-10 Boston Scientific Scimed, Inc. Block copolymer particles
US20070142560A1 (en) * 2005-12-21 2007-06-21 Young-Ho Song Block copolymer particles
ES2554527T3 (es) * 2006-01-24 2015-12-21 Biocompatibles Uk Limited Proceso para rellenar partículas poliméricas con un fármaco
EP2368581B1 (en) * 2006-01-30 2018-08-29 Biosphere Medical, Inc. Porous intravascular embolization particles and related methods
EP1986707A2 (en) 2006-01-30 2008-11-05 Surgica Corporation Compressible intravascular embolization particles and related methods and delivery systems
US7794755B2 (en) 2006-04-11 2010-09-14 E.I. Du Pont De Nemours And Company Process for preparation of swellable and deformable microspheres
US7838035B2 (en) 2006-04-11 2010-11-23 E. I. Du Pont De Nemours And Company Microsphere powder of high density, swellable, deformable, durable occlusion-forming microspheres
US8062673B2 (en) 2006-04-11 2011-11-22 E I Du Pont De Nemours And Company Process for embolization using swellable and deformable microspheres
US8252339B2 (en) 2006-04-11 2012-08-28 Massachusetts Institute Of Technology Medical treatment applications of swellable and deformable microspheres
US20070299461A1 (en) * 2006-06-21 2007-12-27 Boston Scientific Scimed, Inc. Embolic coils and related components, systems, and methods
WO2008014065A1 (en) * 2006-07-27 2008-01-31 Boston Scientific Limited Particles
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
US7943683B2 (en) * 2006-12-01 2011-05-17 Tepha, Inc. Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers
US20080145658A1 (en) * 2006-12-15 2008-06-19 Boston Scientific Scimed, Inc. Freeze Thaw Methods For Making Polymer Particles
US20090092547A1 (en) * 2007-10-05 2009-04-09 Boston Scientific Scimed, Inc. Injectable Particles
US20090110738A1 (en) * 2007-10-26 2009-04-30 Celonova Biosciences, Inc. Loadable Polymeric Particles for Cosmetic and Reconstructive Tissue Augmentation Applications and Methods of Preparing and Using the Same
US20090111763A1 (en) * 2007-10-26 2009-04-30 Celonova Biosciences, Inc. Loadable polymeric particles for bone augmentation and methods of preparing and using the same
US20090110731A1 (en) * 2007-10-30 2009-04-30 Celonova Biosciences, Inc. Loadable Polymeric Microparticles for Therapeutic Use in Alopecia and Methods of Preparing and Using the Same
US20090110730A1 (en) * 2007-10-30 2009-04-30 Celonova Biosciences, Inc. Loadable Polymeric Particles for Marking or Masking Individuals and Methods of Preparing and Using the Same
WO2009120265A2 (en) * 2008-03-25 2009-10-01 Boston Scientific Scimed, Inc. Compositions and methods for delivery of embolics
JP2012507562A (ja) * 2008-10-30 2012-03-29 ダビド リウ 微小球性多孔質生体適合性足場並びにその製造方法及び装置
AU2010303552B2 (en) 2009-10-06 2013-11-14 Regents Of The University Of Minnesota Bioresorbable embolization microspheres
US9700650B2 (en) 2009-11-09 2017-07-11 Spotlight Technology Partners Llc Polysaccharide based hydrogels
NZ599527A (en) 2009-11-09 2014-04-30 Spotlight Technology Partners Llc Fragmented hydrogels
GB201008843D0 (en) * 2010-05-27 2010-07-14 Aubin Ltd Method and composition
US9232805B2 (en) 2010-06-29 2016-01-12 Biocure, Inc. In-situ forming hydrogel wound dressings containing antimicrobial agents
CN101885852B (zh) * 2010-07-07 2012-01-11 天津大学 表面光滑明胶微球与制备方法
BR112013007740B1 (pt) * 2010-09-29 2021-01-12 Scion Cardio-Vascular, Inc. microesferas poliméricas, e seu método de produção
ES2542242T3 (es) 2010-11-29 2015-08-03 Centre Hospitalier Universitaire Vaudois Composición de quimioembolización que comprende agentes antiangiogénicos
GB201101429D0 (en) * 2011-01-27 2011-03-16 Biocompatibles Uk Ltd Drug delivery system
IT1404015B1 (it) * 2011-02-04 2013-11-08 Hsd Holding Smart Device S R L Uso di un polimero di destrano reticolato come filtro contro l'inalazione di sostanze nocive per la salute
CN102492178B (zh) * 2011-11-29 2014-12-24 中国科学院过程工程研究所 一种尺寸均一的魔芋葡甘聚糖微球及其制备方法
BR112014031223B1 (pt) 2012-06-14 2023-03-14 Microvention, Inc Composições de tratamento de polímero
CN104717983B (zh) 2012-10-15 2018-09-18 微仙美国有限公司 聚合治疗组合物
US8936795B2 (en) 2012-12-19 2015-01-20 Regents Of The University Of Minnesota Liquid embolic material including carboxymethyl chitosan crosslinked with carboxymethyl cellulose
US9687573B2 (en) 2013-03-13 2017-06-27 Biosphere Medical, Inc. Compositions and associated methods for radioisotope-binding microparticles
GB2519738A (en) * 2013-09-06 2015-05-06 Biocompatibles Uk Ltd Radiopaque polymers
AU2014321278B2 (en) 2013-09-19 2016-11-10 Microvention, Inc. Polymer films
CN105814120B (zh) 2013-09-19 2019-07-05 泰尔茂株式会社 聚合物颗粒
BR112016010067B1 (pt) 2013-11-08 2023-01-10 Terumo Corporation Partículas de polímero e métodos de preparação
ES2807178T3 (es) 2014-08-15 2021-02-22 Tepha Inc Suturas de autorretención de poli-4-hidroxibutirato y copolímeros del mismo
EP3230500A1 (en) 2014-12-11 2017-10-18 Tepha, Inc. Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof
US10626521B2 (en) 2014-12-11 2020-04-21 Tepha, Inc. Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof
US9907880B2 (en) 2015-03-26 2018-03-06 Microvention, Inc. Particles
US10071181B1 (en) 2015-04-17 2018-09-11 Teleflex Innovations S.À.R.L. Resorbable embolization spheres
KR20180021083A (ko) * 2015-06-19 2018-02-28 신라젠(주) 바이러스성 색전술을 위한 조성물 및 방법
CN105148327B (zh) * 2015-07-29 2019-07-12 广东博与再生医学有限公司 一种多糖-聚乙烯醇栓塞微球的制备方法
US10182979B2 (en) 2016-03-22 2019-01-22 Regents Of The University Of Minnesota Biodegradable microspheres
CN109153968A (zh) * 2016-04-12 2019-01-04 联合细胞Ev股份公司 从生物流体样品中分离细胞外囊泡(ev)
US10368874B2 (en) 2016-08-26 2019-08-06 Microvention, Inc. Embolic compositions
WO2018064389A1 (en) 2016-09-28 2018-04-05 Microvention, Inc. Polymer particles
WO2018070894A1 (ru) * 2016-10-12 2018-04-19 Общество С Ограниченной Ответственностью "Технология Лекарств" Химиоэмболизирующие частицы, способ их получения и применения
EP3694422A4 (en) 2017-10-09 2021-06-30 Microvention, Inc. EMBOLIC RADIOACTIVE LIQUID
CN108744020A (zh) * 2018-06-12 2018-11-06 杭州艾力康医药科技有限公司 一种离子交换型聚乙烯醇微球的制备方法
CN113272347B (zh) 2018-11-21 2024-05-14 株式会社可乐丽 单分散性水凝胶颗粒
JP2023507044A (ja) * 2019-06-19 2023-02-20 ザイロ セラピューティクス,インコーポレーテッド 医薬品および化粧用途のための一酸化窒素担体としての硫黄官能化モノリスおよびそれに由来する粒子
CN114159554B (zh) * 2021-11-22 2022-12-13 广州优理氏生物科技有限公司 一种纤连蛋白-聚乙烯醇微球的制备方法及其应用
CN114642640B (zh) * 2022-05-23 2022-09-16 杭州旸顺医疗科技有限公司 微球及其制备方法、制备系统
CN116159178B (zh) * 2023-04-18 2023-07-04 上海汇禾医疗器械有限公司 一种小粒径栓塞微球及其制备方法

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US499188A (en) * 1893-06-06 Territory
US3919411A (en) 1972-01-31 1975-11-11 Bayvet Corp Injectable adjuvant and compositions including such adjuvant
JPS49108168A (US07585860-20090908-C00150.png) 1973-02-16 1974-10-15
JPS49108158A (US07585860-20090908-C00150.png) 1973-02-19 1974-10-15
JPS5350290A (en) 1976-10-18 1978-05-08 Sumitomo Chem Co Ltd Preparation f hydrogel
CA1134977A (en) * 1978-09-07 1982-11-02 Sumitomo Chemical Co., Ltd. Method for preparing highly absorbent polymers
US4314032A (en) * 1978-10-26 1982-02-02 Kureha Kagaku Kogyo Kabushiki Kaisha Crosslinked polyvinyl alcohol gel
US4268495A (en) 1979-01-08 1981-05-19 Ethicon, Inc. Injectable embolization and occlusion solution
US4306031A (en) * 1979-08-14 1981-12-15 Mitsubishi Chemical Industries Limited Weakly acidic cation exchange resin and process for producing same
GB2088392B (en) * 1980-12-03 1984-05-02 Sumitomo Chemical Co Production of hydrogels
JPS57128709A (en) 1981-02-03 1982-08-10 Sumitomo Chem Co Ltd Preparation of hydrogel
CA1225585A (en) 1983-06-30 1987-08-18 Maria T. Litvinova Composition for embolization of blood vessels
GB8418772D0 (en) 1984-07-24 1984-08-30 Geistlich Soehne Ag Chemical substances
US4680171A (en) * 1985-03-15 1987-07-14 William Shell Visualization of a bloodstream circulation with biodegradable microspheres
US5186922A (en) * 1985-03-15 1993-02-16 See/Shell Biotechnology, Inc. Use of biodegradable microspheres labeled with imaging energy constrast materials
EP0229165A4 (en) 1985-07-02 1988-07-25 Target Therapeutics Inc PROCESS AND COMPOSITION OF VASO-OCCLUSIVE COLLAGEN.
US4803075A (en) 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
JPS6317904A (ja) * 1986-07-09 1988-01-25 Mitsubishi Chem Ind Ltd 多孔質架橋ポリビニルアルコ−ル粒子の製造法
CA1329800C (en) * 1987-12-29 1994-05-24 Hiroaki Takayanagi Composite separating agent
GB8813425D0 (en) 1988-06-07 1988-07-13 Hall L D Magnetic resonance imaging
JPH064713B2 (ja) * 1988-07-22 1994-01-19 テルモ株式会社 生体適合性材料
JPH0286838A (ja) * 1988-09-22 1990-03-27 Terumo Corp 水不溶性ヒドロゲルおよびその製造方法
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5258028A (en) 1988-12-12 1993-11-02 Ersek Robert A Textured micro implants
US5092883A (en) 1988-12-28 1992-03-03 Eppley Barry L Method for promoting soft connective tissue growth and repair in mammals
GB8900376D0 (en) * 1989-01-09 1989-03-08 Nycomed As Iodinated esters
US5007940A (en) 1989-06-09 1991-04-16 American Medical Systems, Inc. Injectable polymeric bodies
EP0470569B1 (en) 1990-08-08 1995-11-22 Takeda Chemical Industries, Ltd. Intravascular embolizing agent containing angiogenesis inhibiting substance
US5410016A (en) * 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
EP0526608B1 (fr) * 1991-02-25 1996-12-18 Debiopharm S.A. Agents therapeutiques pour le traitement de la resistance multidrogue de cancers
FR2676927B1 (fr) 1991-05-29 1995-06-23 Ibf Microspheres utilisables pour les occlusions vasculaires therapeutiques et solutions injectables les contenant.
JP3356447B2 (ja) * 1991-10-16 2002-12-16 テルモ株式会社 乾燥高分子ゲルからなる血管病変塞栓材料
PT627911E (pt) * 1992-02-28 2001-04-30 Univ Texas Hidrogeis biodegradaveis fotopolimerizaveis como materiais de contacto de tecidos e veiculos de libertacao controlada
JPH0656676A (ja) 1992-08-05 1994-03-01 Hori Shinichi 血管塞栓用懸濁液
US5629327A (en) 1993-03-01 1997-05-13 Childrens Hospital Medical Center Corp. Methods and compositions for inhibition of angiogenesis
DE69408527T2 (de) 1993-03-09 1998-06-04 Epic Therapeutics, Inc., Norwood, Mass. Makromolekulare mikropartikel und verfahren zu ihrer herstellung
UA10911C2 (uk) 1994-08-10 1996-12-25 Мале Впроваджувальне Підприємство "Іhтерфалл" Біосумісhий гідрогель
US5955108A (en) 1994-12-16 1999-09-21 Quadrant Healthcare (Uk) Limited Cross-linked microparticles and their use as therapeutic vehicles
CA2207667A1 (en) * 1995-01-27 1996-08-01 Scimed Life Systems, Inc. Embolizing system
US5752974A (en) * 1995-12-18 1998-05-19 Collagen Corporation Injectable or implantable biomaterials for filling or blocking lumens and voids of the body
DE19601699A1 (de) * 1996-01-18 1997-07-24 Wacker Chemie Gmbh Redispergierbare Polymerisatpulver und daraus erhältliche wäßrige Polymerisat-Dispersionen
US5785977A (en) 1996-02-07 1998-07-28 Breithbarth; Richard Non-metallic microparticle carrier materials
US5803075A (en) * 1996-03-15 1998-09-08 Yaru Llc Surgical mask with adhesive strip to improve breathing
US5925683A (en) * 1996-10-17 1999-07-20 Target Therapeutics, Inc. Liquid embolic agents
US6139963A (en) * 1996-11-28 2000-10-31 Kuraray Co., Ltd. Polyvinyl alcohol hydrogel and process for producing the same
AU9313298A (en) 1997-09-04 1999-03-22 Point Biomedical Corporation Injectable tissue reconstruction material
WO1999012577A1 (en) * 1997-09-05 1999-03-18 Nycomed Imaging As Polymer particles made of polyvinyl alcohol and comprising a contrast agent for chemoembolization
US6565885B1 (en) * 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6660301B1 (en) 1998-03-06 2003-12-09 Biosphere Medical, Inc. Injectable microspheres for dermal augmentation and tissue bulking
EP1059943B1 (en) 1998-03-06 2004-12-01 Biosepra Medical Inc. Implantable particles for tissue bulking and the treatment of gastroesophageal reflux disease, urinary incontinence, and skin wrinkles
US6165193A (en) * 1998-07-06 2000-12-26 Microvention, Inc. Vascular embolization with an expansible implant
FR2784580B1 (fr) 1998-10-16 2004-06-25 Biosepra Inc Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci
US6710126B1 (en) * 1999-11-15 2004-03-23 Bio Cure, Inc. Degradable poly(vinyl alcohol) hydrogels
KR100335866B1 (ko) * 2000-01-06 2002-05-10 박호군 폴리아세트산비닐 코어/폴리비닐알코올 외피의 2중 구조를갖는 미세구형 색전재료 및 그의 제조방법
US6676971B2 (en) * 2000-03-13 2004-01-13 Biocure, Inc. Embolic compositions
US6652883B2 (en) * 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
WO2001070289A2 (en) 2000-03-20 2001-09-27 Biosphere Medical, Inc. Injectable and swellable microspheres for tissue bulking
US6436424B1 (en) 2000-03-20 2002-08-20 Biosphere Medical, Inc. Injectable and swellable microspheres for dermal augmentation
US7338657B2 (en) 2001-03-15 2008-03-04 Biosphere Medical, Inc. Injectable microspheres for tissue construction
US20030212022A1 (en) 2001-03-23 2003-11-13 Jean-Marie Vogel Compositions and methods for gene therapy
DE01918975T1 (de) 2000-03-24 2006-04-13 Biosphere Medical, Inc., Rockland Mikrokügelchen zur aktiven Embolisierung
US6537569B2 (en) * 2001-02-14 2003-03-25 Microvention, Inc. Radiation cross-linked hydrogels
WO2002100444A1 (en) 2001-06-08 2002-12-19 Biosphere Medical Inc. Colloidal metal labelled microparticles, their production and use
US6488952B1 (en) * 2001-08-28 2002-12-03 John P. Kennedy Semisolid therapeutic delivery system and combination semisolid, multiparticulate, therapeutic delivery system
US6911219B2 (en) 2001-09-27 2005-06-28 Surgica Corporation Partially acetalized polyvinyl alcohol embolization particles, compositions containing those particles and methods of making and using them
WO2006119968A2 (en) 2005-05-09 2006-11-16 Biosphere Medical S.A. Compositions and methods using microspheres and non-ionic contrast agents
EP2368581B1 (en) 2006-01-30 2018-08-29 Biosphere Medical, Inc. Porous intravascular embolization particles and related methods
EP1986707A2 (en) 2006-01-30 2008-11-05 Surgica Corporation Compressible intravascular embolization particles and related methods and delivery systems

Similar Documents

Publication Publication Date Title
BE2018C020I2 (US07585860-20090908-C00150.png)
BE2016C007I2 (US07585860-20090908-C00150.png)
BE2015C057I2 (US07585860-20090908-C00150.png)
BE2015C018I2 (US07585860-20090908-C00150.png)
BE2014C017I2 (US07585860-20090908-C00150.png)
BE2013C051I2 (US07585860-20090908-C00150.png)
BE2013C020I2 (US07585860-20090908-C00150.png)
BE2013C015I2 (US07585860-20090908-C00150.png)
BE2013C001I2 (US07585860-20090908-C00150.png)
BE2012C036I2 (US07585860-20090908-C00150.png)
BE2011C004I2 (US07585860-20090908-C00150.png)
BE2010C011I2 (US07585860-20090908-C00150.png)
IN2001CH01553A (US07585860-20090908-C00150.png)
BE2008C046I2 (US07585860-20090908-C00150.png)
BRPI0017527B8 (US07585860-20090908-C00150.png)
JP2002527206A5 (US07585860-20090908-C00150.png)
BE2008C047I2 (US07585860-20090908-C00150.png)
BRPI0001672A2 (US07585860-20090908-C00150.png)
BRPI0001542A2 (US07585860-20090908-C00150.png)
JP2002529163A5 (US07585860-20090908-C00150.png)
JP2002512903A5 (US07585860-20090908-C00150.png)
JP2002531741A5 (US07585860-20090908-C00150.png)
JP2002523062A5 (US07585860-20090908-C00150.png)
BRPI0012675B8 (US07585860-20090908-C00150.png)
BRPI0017522A2 (US07585860-20090908-C00150.png)