JP2002080321A5 - - Google Patents

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Publication number
JP2002080321A5
JP2002080321A5 JP2001185774A JP2001185774A JP2002080321A5 JP 2002080321 A5 JP2002080321 A5 JP 2002080321A5 JP 2001185774 A JP2001185774 A JP 2001185774A JP 2001185774 A JP2001185774 A JP 2001185774A JP 2002080321 A5 JP2002080321 A5 JP 2002080321A5
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JP
Japan
Prior art keywords
proline
hydroxyproline
hydroxy
cosmetic according
cis
Prior art date
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Pending
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JP2001185774A
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Japanese (ja)
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JP2002080321A (en
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Priority to JP2001185774A priority Critical patent/JP2002080321A/en
Priority claimed from JP2001185774A external-priority patent/JP2002080321A/en
Publication of JP2002080321A publication Critical patent/JP2002080321A/en
Publication of JP2002080321A5 publication Critical patent/JP2002080321A5/ja
Pending legal-status Critical Current

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Description

【特許請求の範囲】
【請求項1】(1)ヒドロキシプロリンもしくはヒドロキシプロリンのN−アシル化誘導体またはその塩と、
(2)水溶性ビタミン、油溶性ビタミン、高分子ペプチド、高分子多糖、スフィンゴ脂質および海草エキスからなる群から選ばれる成分の少なくとも1つとを含有してなる化粧料。
【請求項2】 ヒドロキシプロリンもしくはヒドロキシプロリンのN−アシル化誘導体またはその塩を全重量に対し0.01〜5重量%含有する請求項1記載の化粧料。
【請求項3】 ヒドロキシプロリンが、シス−4−ヒドロキシ−L−プロリン、シス−4−ヒドロキシ−D−プロリン、シス−3−ヒドロキシ−L−プロリン、シス−3−ヒドロキシ−D−プロリン、トランス−4−ヒドロキシ−L−プロリン、トランス−4−ヒドロキシ−D−プロリン、トランス−3−ヒドロキシ−L−プロリンおよびトランス−3−ヒドロキシ−D−プロリンからなる群より選ばれるヒドロキシプロリンである、請求項1または2記載の化粧料。
【請求項4】 ヒドロキシプロリンが、微生物により生産されたヒドロキシプロリンである、請求項1〜3のいずれかに記載の化粧料。
【請求項5】 微生物が、アミコラトプシス属、ダクチロスポランジウム属およびストレプトマイセス属から選ばれる属に属する微生物由来のプロリン3位水酸化酵素またはプロリン4位水酸化酵素遺伝子を導入された微生物である、請求項4記載の化粧料。
【請求項6】 ヒドロキシプロリンのN−アシル化誘導体のアシル部分が、炭素数2〜23のアシルである、請求項1または2記載の化粧料。
【請求項7】 ヒドロキシプロリンのN−アシル化誘導体が、N−アセチ化誘導体またはN−プロピオニル化誘導体である、請求項1または2記載の化粧料。
【請求項8】 水溶性ビタミン、油溶性ビタミン、高分子ペプチド、高分子多糖、スフィンゴ脂質および海草エキスからなる群から選ばれる成分を全重量に対し0.0001〜10重量%含有する請求項1〜のいずれかに記載の化粧料。
[Claims]
(1) hydroxyproline or an N-acylated derivative of hydroxyproline or a salt thereof,
(2) A cosmetic comprising at least one component selected from the group consisting of water-soluble vitamins, oil-soluble vitamins, high molecular peptides, high molecular polysaccharides, sphingolipids and seaweed extracts.
2. The cosmetic according to claim 1, which contains 0.01 to 5% by weight of hydroxyproline or an N-acylated derivative of hydroxyproline or a salt thereof based on the total weight.
3. Hydroxyproline is cis-4-hydroxy-L-proline, cis-4-hydroxy-D-proline, cis-3-hydroxy-L-proline, cis-3-hydroxy-D-proline, trans A hydroxyproline selected from the group consisting of -4-hydroxy-L-proline, trans-4-hydroxy-D-proline, trans-3-hydroxy-L-proline and trans-3-hydroxy-D-proline. Item 3. The cosmetic according to item 1 or 2.
4. The cosmetic according to claim 1, wherein the hydroxyproline is hydroxyproline produced by a microorganism.
5. The microorganism has a proline 3-hydroxylase or proline 4-hydroxylase gene derived from a microorganism belonging to a genus selected from the genus Amycolatopsis, Dactylosporandium and Streptomyces. The cosmetic according to claim 4, which is a microorganism.
6. The cosmetic according to claim 1, wherein the acyl moiety of the N-acylated derivative of hydroxyproline is an acyl having 2 to 23 carbon atoms.
7. The cosmetic according to claim 1 or 2, wherein the N-acylated derivative of hydroxyproline is an N-acetylated derivative or an N-propionylated derivative.
Claim 8.  The composition according to claim 1, further comprising 0.0001 to 10% by weight of a component selected from the group consisting of water-soluble vitamins, oil-soluble vitamins, high molecular weight peptides, high molecular weight polysaccharides, sphingolipids and seaweed extract.7The cosmetic according to any one of the above.

JP2001185774A 2000-06-20 2001-06-20 Cosmetic Pending JP2002080321A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2001185774A JP2002080321A (en) 2000-06-20 2001-06-20 Cosmetic

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000-183937 2000-06-20
JP2000183937 2000-06-20
JP2001185774A JP2002080321A (en) 2000-06-20 2001-06-20 Cosmetic

Publications (2)

Publication Number Publication Date
JP2002080321A JP2002080321A (en) 2002-03-19
JP2002080321A5 true JP2002080321A5 (en) 2006-05-18

Family

ID=26594240

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001185774A Pending JP2002080321A (en) 2000-06-20 2001-06-20 Cosmetic

Country Status (1)

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JP (1) JP2002080321A (en)

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