JP2001501933A5 - - Google Patents

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Publication number
JP2001501933A5
JP2001501933A5 JP1998516754A JP51675498A JP2001501933A5 JP 2001501933 A5 JP2001501933 A5 JP 2001501933A5 JP 1998516754 A JP1998516754 A JP 1998516754A JP 51675498 A JP51675498 A JP 51675498A JP 2001501933 A5 JP2001501933 A5 JP 2001501933A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1998516754A
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English (en)
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JP2001501933A (ja
Filing date
Publication date
Priority claimed from US08/720,487 external-priority patent/US5876727A/en
Application filed filed Critical
Publication of JP2001501933A publication Critical patent/JP2001501933A/ja
Publication of JP2001501933A5 publication Critical patent/JP2001501933A5/ja
Withdrawn legal-status Critical Current

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Figure 2001501933
Figure 2001501933
Figure 2001501933
Figure 2001501933
Figure 2001501933
JP10516754A 1996-09-30 1997-09-30 薬物濫用の治療で使用するハプテン―キャリア結合体およびそれを調製する方法 Withdrawn JP2001501933A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/720,487 1996-09-30
US08/720,487 US5876727A (en) 1995-03-31 1996-09-30 Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
PCT/US1997/017506 WO1998014216A2 (en) 1996-09-30 1997-09-30 Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009171424A Division JP2009280599A (ja) 1996-09-30 2009-07-22 薬物濫用の治療で使用するハプテン−キャリア結合体およびそれを調製する方法

Publications (2)

Publication Number Publication Date
JP2001501933A JP2001501933A (ja) 2001-02-13
JP2001501933A5 true JP2001501933A5 (ja) 2006-06-22

Family

ID=24894184

Family Applications (2)

Application Number Title Priority Date Filing Date
JP10516754A Withdrawn JP2001501933A (ja) 1996-09-30 1997-09-30 薬物濫用の治療で使用するハプテン―キャリア結合体およびそれを調製する方法
JP2009171424A Pending JP2009280599A (ja) 1996-09-30 2009-07-22 薬物濫用の治療で使用するハプテン−キャリア結合体およびそれを調製する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009171424A Pending JP2009280599A (ja) 1996-09-30 2009-07-22 薬物濫用の治療で使用するハプテン−キャリア結合体およびそれを調製する方法

Country Status (14)

Country Link
US (1) US5876727A (ja)
EP (2) EP1024834B1 (ja)
JP (2) JP2001501933A (ja)
CN (3) CN1235640C (ja)
AT (1) ATE372786T1 (ja)
AU (1) AU733980B2 (ja)
BR (1) BR9711580A (ja)
CA (2) CA2267456C (ja)
DE (1) DE69738140T2 (ja)
DK (1) DK1024834T3 (ja)
ES (1) ES2293664T3 (ja)
HK (2) HK1027293A1 (ja)
PT (1) PT1024834E (ja)
WO (1) WO1998014216A2 (ja)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840307A (en) 1995-03-31 1998-11-24 Immulogic Pharmacuetical Corp. Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation
US5876727A (en) * 1995-03-31 1999-03-02 Immulogic Pharmaceutical Corporation Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
US20020032316A1 (en) * 1995-03-31 2002-03-14 Cantab Pharmaceuticals Research Limited Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
AU719289B2 (en) 1995-12-14 2000-05-04 Scripps Research Institute, The Anti-cocaine vaccine
US5817770A (en) 1997-03-21 1998-10-06 Drug Abuse Sciences, Inc. Cocaethylene immunogens and antibodies
US6455047B1 (en) * 1997-09-19 2002-09-24 Serex, Inc. Methods to improve immunogenicity of antigens and specificity of antibodies
SE9801923D0 (sv) * 1998-05-29 1998-05-29 Independent Pharmaceutical Ab Nicotine vaccine
US6362371B1 (en) * 1998-06-08 2002-03-26 Advanced Medicine, Inc. β2- adrenergic receptor agonists
US6858211B1 (en) * 1998-07-20 2005-02-22 The United States Of America As Represented By The Department Of Health And Human Services Vaccines against Escherichia coli O157 infection
US6232082B1 (en) * 1998-12-01 2001-05-15 Nabi Hapten-carrier conjugates for treating and preventing nicotine addiction
GB2361473C (en) * 2000-03-08 2005-06-28 Microgenics Corp Ecstasy-class analogs and use of same in detection of ecstasy-class compounds
GB0031079D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Vaccine
WO2002058635A2 (en) * 2001-01-26 2002-08-01 The Scripps Research Institute Nicotine immunogens and antibodies and uses thereof
NZ511705A (en) * 2001-05-14 2004-03-26 Horticulture & Food Res Inst Methods and rapid immunoassay device for detecting progesterone and other steroids
WO2002102791A1 (en) * 2001-06-15 2002-12-27 Vicuron Pharmaceuticals Inc. Pyrrolidine bicyclic compounds
US7115266B2 (en) * 2001-10-05 2006-10-03 Cytos Biotechnology Ag Angiotensin peptide-carrier conjugates and uses thereof
MXPA04002644A (es) 2001-10-05 2004-07-08 Cytos Biotechnology Ag Conjugados que portan un peptido de angiotensina y usos de los mismos.
WO2003082329A2 (en) * 2002-03-01 2003-10-09 The Board Of Regents Of The University Of Nebraska Compositions and compounds for use as molecular adjuvant for a nicotine vaccine
IL165249A0 (en) 2002-07-18 2005-12-18 Cytos Biotechnology Ag Hapten-carrier conjugates and uses thereof
ATE445611T1 (de) * 2003-11-17 2009-10-15 Univ North Carolina State Regiospezifische synthese von nikotinderivaten
US7279340B2 (en) * 2004-04-07 2007-10-09 Dade Behring Inc. Synthesis and application of procainamide analogs for use in an immunoassay
MXPA04006617A (es) 2004-07-07 2006-01-12 Inst Nac De Psiquiatria Ramon Proceso para la preparacion y uso de una vacuna bivalente contra la adiccion a la morfina-heroina.
US9492400B2 (en) * 2004-11-04 2016-11-15 Massachusetts Institute Of Technology Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
FR2877668B1 (fr) * 2004-11-10 2007-07-06 Gemac Sa Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations
US9267937B2 (en) 2005-12-15 2016-02-23 Massachusetts Institute Of Technology System for screening particles
WO2008105773A2 (en) * 2006-03-31 2008-09-04 Massachusetts Institute Of Technology System for targeted delivery of therapeutic agents
JP5630998B2 (ja) 2006-05-15 2014-11-26 マサチューセッツ インスティテュート オブ テクノロジー 機能的粒子のためのポリマー
US20110052697A1 (en) * 2006-05-17 2011-03-03 Gwangju Institute Of Science & Technology Aptamer-Directed Drug Delivery
US9381477B2 (en) * 2006-06-23 2016-07-05 Massachusetts Institute Of Technology Microfluidic synthesis of organic nanoparticles
WO2008019142A2 (en) * 2006-08-04 2008-02-14 Massachusetts Institute Of Technology Oligonucleotide systems for targeted intracellular delivery
WO2008147456A2 (en) * 2006-11-20 2008-12-04 Massachusetts Institute Of Technology Drug delivery systems using fc fragments
WO2008098165A2 (en) 2007-02-09 2008-08-14 Massachusetts Institute Of Technology Oscillating cell culture bioreactor
WO2008124632A1 (en) * 2007-04-04 2008-10-16 Massachusetts Institute Of Technology Amphiphilic compound assisted nanoparticles for targeted delivery
EP3424525A1 (en) 2007-10-12 2019-01-09 Massachusetts Institute Of Technology Vaccine nanotechnology
CN102056624A (zh) * 2008-06-04 2011-05-11 康奈尔大学 用于防治成瘾的疫苗
US20110182918A1 (en) 2008-06-13 2011-07-28 Nabi Biopharmaceuticals Personalized drug treatment and smoking cessation kit and method
US8343497B2 (en) 2008-10-12 2013-01-01 The Brigham And Women's Hospital, Inc. Targeting of antigen presenting cells with immunonanotherapeutics
US8343498B2 (en) 2008-10-12 2013-01-01 Massachusetts Institute Of Technology Adjuvant incorporation in immunonanotherapeutics
US8591905B2 (en) 2008-10-12 2013-11-26 The Brigham And Women's Hospital, Inc. Nicotine immunonanotherapeutics
US8277812B2 (en) 2008-10-12 2012-10-02 Massachusetts Institute Of Technology Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
EP2405943A2 (en) 2009-03-09 2012-01-18 William Henry Hapten-carrier conjugates with bacterial toxins having a signal peptide as carrier and their use in immunogenic compositions
KR20120022984A (ko) * 2009-04-21 2012-03-12 셀렉타 바이오사이언시즈, 인크. Ｔｈ１ 편향 반응을 제공하는 면역나노치료법
WO2011014679A1 (en) 2009-07-31 2011-02-03 Nabi Biopharmaceuticals Method and kit for treating nicotine addiction
EP2477974A2 (en) * 2009-09-14 2012-07-25 The Scripps Research Institute Nicotine haptens, immunoconjugates and their uses
CN102892429B (zh) 2010-03-17 2016-08-31 康奈尔大学 基于被破坏的腺病毒的抗滥用药物疫苗
WO2011123042A1 (en) * 2010-04-01 2011-10-06 Independent Pharmaceutica Ab Vaccination procedure and products for use therein
GB201006324D0 (en) 2010-04-15 2010-06-02 Glaxosmithkline Biolog Sa Vaccine
CN102905728B (zh) 2010-05-26 2015-11-25 西莱克塔生物科技公司 具有不偶合的佐剂的纳米载体组合物
TWI578997B (zh) * 2010-06-04 2017-04-21 輝瑞疫苗有限責任公司 用於預防或治療菸鹼成癮之共軛體
EP2640190A4 (en) 2010-11-05 2016-05-11 Selecta Biosciences Inc MODIFIED NICOTINIC COMPOUNDS AND ASSOCIATED METHODS
CN103702687A (zh) 2011-07-29 2014-04-02 西莱克塔生物科技公司 产生体液和细胞毒性t淋巴细胞（ctl）免疫应答的合成纳米载体
US20130189754A1 (en) 2011-09-12 2013-07-25 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
US9347065B2 (en) 2012-03-29 2016-05-24 International Aids Vaccine Initiative Methods to improve vector expression and genetic stability
US10004811B2 (en) 2012-04-13 2018-06-26 Cornell University Development of a highly efficient second generation nicotine-conjugate vaccine to treat nicotine addiction
US9694069B2 (en) 2013-03-14 2017-07-04 Alere San Diego, Inc. 6-acetylmorphine analogs, and methods for their synthesis and use
CN106458971A (zh) 2014-05-19 2017-02-22 斯克利普斯研究院 用于尼古丁疫苗开发的光学纯半抗原
CA3041631A1 (en) * 2016-10-24 2018-05-03 The Scripps Research Institute Anti-opioid vaccines
AU2018283973A1 (en) 2017-06-11 2020-01-16 Molecular Express, Inc. Methods and compositions for substance use disorder vaccine formulations and uses thereof
CN108409749B (zh) * 2018-01-30 2019-09-06 中国农业科学院蜜蜂研究所 钩吻素己半抗原和全抗原及其制备方法与应用
US20220214336A1 (en) * 2019-01-29 2022-07-07 Teknologian Tutkimuskeskus Vtt Oy Methods for screening polypeptides capable of binding specific target molecules and tools related thereto
CN113999163A (zh) * 2021-11-03 2022-02-01 公安部第三研究所 合成大麻素半抗原化合物及其制备方法和用途
CN115974836A (zh) * 2023-01-16 2023-04-18 浙江安诺和生物医药有限公司 一种s-(-)-6-甲基尼古丁水杨酸盐及其制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4375414A (en) * 1971-05-20 1983-03-01 Meir Strahilevitz Immunological methods for removing species from the blood circulatory system and devices therefor
US3766162A (en) * 1971-08-24 1973-10-16 Hoffmann La Roche Barbituric acid antigens and antibodies specific therefor
US4045420A (en) * 1973-05-29 1977-08-30 Syva Company Non-oxo-carbonyl containing benzoyl ecgonine and cocaine compounds polypeptide and derivatives thereof
US4053459A (en) * 1975-09-24 1977-10-11 Hoffmann-La Roche Inc. Antibody specific to methaqualone and its metabolites
SU792869A1 (ru) * 1979-03-30 1982-03-30 Научно-Исследовательский Институт По Биологическим Испытаниям Химических Соединений Способ получени конъюгированных антигенов барбитурова кислота-иммуногенный носитель
SU1123704A1 (ru) * 1983-04-08 1984-11-15 Научно-Исследовательский Институт По Биологическим Испытаниям Химических Соединений Способ получени конъюгированных антигенов
US5229490A (en) * 1987-05-06 1993-07-20 The Rockefeller University Multiple antigen peptide system
DE3884731D1 (de) * 1987-10-09 1993-11-11 Ube Industries Monoklonaler Antikörper gegen Methamphetamin, seine Herstellung, Testverfahren und Testsatz für Methamphetamin.
JP2762310B2 (ja) * 1988-03-25 1998-06-04 ザ ロックフェラー ユニバーシティ ストレプトコッカルｍプロテイン由来の合成ペプタイド及び当該ペプタイドから調製されたワクチン
EP0363041A1 (en) * 1988-09-21 1990-04-11 Ube Industries, Ltd. Monoclonal antibody to morphine, preparation of monoclonal antibody, assaying kit and assaying method of morphine
GB8924438D0 (en) * 1989-10-31 1989-12-20 Hoffmann La Roche Vaccine composition
IL96475A0 (en) * 1989-11-29 1991-08-16 Innovative Tech Center Chimeric proteins
CH678394A5 (ja) * 1990-08-22 1991-09-13 Cerny Erich H
US5256066A (en) * 1991-03-14 1993-10-26 Larussa Joseph Hybridized target acquisition trainer
GB9112553D0 (en) * 1991-06-11 1991-07-31 Wellcome Found Fusion proteins
US5283066A (en) * 1992-02-19 1994-02-01 Development Center For Biotechnology Method of stimulating an immune response by using a hapten
WO1993023076A1 (en) * 1992-05-20 1993-11-25 The Johns-Hopkins University Alternative receptor therapy
GB9310412D0 (en) * 1993-05-20 1993-07-07 Danbiosyst Uk Nasal nicotine system
US5876727A (en) * 1995-03-31 1999-03-02 Immulogic Pharmaceutical Corporation Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
WO1996030049A2 (en) * 1995-03-31 1996-10-03 Immulogic Pharmaceutical Corporation Hapten-carrier conjugates for use in drug-abuse therapy

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