JO1768B1 - Synergistic combination of a substance with gastric acid secretion inhibiting effect and an acid degradable antibiotic - Google Patents
Synergistic combination of a substance with gastric acid secretion inhibiting effect and an acid degradable antibioticInfo
- Publication number
- JO1768B1 JO1768B1 JO19931768A JOP19931768A JO1768B1 JO 1768 B1 JO1768 B1 JO 1768B1 JO 19931768 A JO19931768 A JO 19931768A JO P19931768 A JOP19931768 A JO P19931768A JO 1768 B1 JO1768 B1 JO 1768B1
- Authority
- JO
- Jordan
- Prior art keywords
- substance
- acid degradable
- acid
- inhibiting effect
- synergistic combination
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention consists of a combination of a substance that increases the intragastric pH and an acid degradable antibacterial compound. By this combined product regimen it will be possible to obtain maximal local antibacterial effect of acid degradable antibiotics as well as enhanced bioavailability of the active antibiotic, thus resulting in higher amounts of the active compound in the gastric mucosa due to secretion of weak bases. Both pharmacological effects contribute to drastically increased antimicrobial capacity of acid degradable antibiotics to be used against local infections in the gastrointestinal tract causing gastritis and/or peptic ulcer. The invention also selects to the use of said combination and a process for the preparation thereof.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JO19931768A JO1768B1 (en) | 1993-10-24 | 1993-10-24 | Synergistic combination of a substance with gastric acid secretion inhibiting effect and an acid degradable antibiotic |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JO19931768A JO1768B1 (en) | 1993-10-24 | 1993-10-24 | Synergistic combination of a substance with gastric acid secretion inhibiting effect and an acid degradable antibiotic |
Publications (1)
Publication Number | Publication Date |
---|---|
JO1768B1 true JO1768B1 (en) | 1994-05-15 |
Family
ID=48092610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JO19931768A JO1768B1 (en) | 1993-10-24 | 1993-10-24 | Synergistic combination of a substance with gastric acid secretion inhibiting effect and an acid degradable antibiotic |
Country Status (1)
Country | Link |
---|---|
JO (1) | JO1768B1 (en) |
-
1993
- 1993-10-24 JO JO19931768A patent/JO1768B1/en active
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