ITPI20060103A1 - Hybrids with pharmacodynamic activity 'hypoglycemic and no-donor obtained from the conjugation of hydroxylated derivatives of glibenclamide with nitroxy-substituted carboxylic acids. - Google Patents

Hybrids with pharmacodynamic activity 'hypoglycemic and no-donor obtained from the conjugation of hydroxylated derivatives of glibenclamide with nitroxy-substituted carboxylic acids.

Info

Publication number
ITPI20060103A1
ITPI20060103A1 ITPI20060103A ITPI20060103A1 IT PI20060103 A1 ITPI20060103 A1 IT PI20060103A1 IT PI20060103 A ITPI20060103 A IT PI20060103A IT PI20060103 A1 ITPI20060103 A1 IT PI20060103A1
Authority
IT
Italy
Prior art keywords
nitroxy
glibenclamide
hypoglycemic
hybrids
conjugation
Prior art date
Application number
Other languages
Italian (it)
Inventor
Aldo Balsamo
Vincenzo Calderone
Piero Marchetti
Simona Rapposelli
Scilla Torri
Original Assignee
Univ Pisa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pisa filed Critical Univ Pisa
Priority to ITPI20060103 priority Critical patent/ITPI20060103A1/en
Publication of ITPI20060103A1 publication Critical patent/ITPI20060103A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52Y being a hetero atom
    • C07C311/54Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/59Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of rings other than six-membered aromatic rings
ITPI20060103 2006-08-07 2006-08-07 Hybrids with pharmacodynamic activity 'hypoglycemic and no-donor obtained from the conjugation of hydroxylated derivatives of glibenclamide with nitroxy-substituted carboxylic acids. ITPI20060103A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ITPI20060103 ITPI20060103A1 (en) 2006-08-07 2006-08-07 Hybrids with pharmacodynamic activity 'hypoglycemic and no-donor obtained from the conjugation of hydroxylated derivatives of glibenclamide with nitroxy-substituted carboxylic acids.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITPI20060103 ITPI20060103A1 (en) 2006-08-07 2006-08-07 Hybrids with pharmacodynamic activity 'hypoglycemic and no-donor obtained from the conjugation of hydroxylated derivatives of glibenclamide with nitroxy-substituted carboxylic acids.
PCT/IB2007/002259 WO2008017925A2 (en) 2006-08-07 2007-08-06 Pharmacodynamic hybrids endowed of hypoglycemic and no-donor activities obtained combining hydroxylated derivatives of glibenclamide and nitrooxy-substituted carboxylic acids
EP20070804717 EP2054381A2 (en) 2006-08-07 2007-08-06 Pharmacodynamic hybrids endowed of hypoglycemic and no-donor activities obtained combining hydroxylated derivatives of glibenclamide and nitrooxy-substituted carboxylic acids

Publications (1)

Publication Number Publication Date
ITPI20060103A1 true ITPI20060103A1 (en) 2008-02-08

Family

ID=38896936

Family Applications (1)

Application Number Title Priority Date Filing Date
ITPI20060103 ITPI20060103A1 (en) 2006-08-07 2006-08-07 Hybrids with pharmacodynamic activity 'hypoglycemic and no-donor obtained from the conjugation of hydroxylated derivatives of glibenclamide with nitroxy-substituted carboxylic acids.

Country Status (3)

Country Link
EP (1) EP2054381A2 (en)
IT (1) ITPI20060103A1 (en)
WO (1) WO2008017925A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105237445A (en) * 2015-10-20 2016-01-13 大连九信生物化工科技有限公司 Synthetic process of 4-[2-(5-chloro-2-methoxy benzamide)ethyl]benzsulfamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU0002628A2 (en) * 2000-07-14 2002-06-29 Keri Pharma Kft Pharmaceutical combinations for treating diabetes
IT1319201B1 (en) * 2000-10-12 2003-09-26 Nicox Sa Drugs for diabetes.

Also Published As

Publication number Publication date
WO2008017925A3 (en) 2008-11-06
WO2008017925A2 (en) 2008-02-14
EP2054381A2 (en) 2009-05-06

Similar Documents

Publication Publication Date Title
AT345829T (en) Needleless injector
RU2005138856A (en) The whippable food product with improved stability
NO339552B1 (en) injection device
DE60213861D1 (en) Orodispersible tablets with fexofenadine
NO339185B1 (en) injection device
RU2005136304A (en) Reduced accidental activation of the sensor device
RU2005112448A (en) Corrugated structure with the possibility of RFID
RU2005129848A (en) The structure of the display area
RU2006104706A (en) Tractor with tracks for the open hole
RU2005124681A (en) The feedback loop in order to prevent spam
ID26437A (en) The barge with horizontal rails
NO2019033I1 (en) regorafenib
RU2005115957A (en) Flameless Electronic Cigarette with spray
ECSP045381A (en) Polypeptides and biosynthetic pathways
EE05194B1 (en) ACID derivatives with pharmaceutical properties aminodikarboks
NO341073B1 (en) carbonylation
AT324567T (en) Tape measure with laser
RU2006103083A (en) The food bar
NO339242B1 (en) injection device
NL1030486A1 (en) Dibenzylamineverbindingen and derivatives.
AT342857T (en) Article reverser
RU2006113577A (en) Antisymmetrised electromagnetic measurements
RU2005129182A (en) Apparatus for producing a fuel (variants) and the system for producing an alkyl ester of (variants)
NL1026071A1 (en) Collimator assembly with multi-part components.
NO341310B1 (en) A Mortierella alpina C16 / 18 fettsyreelongase