IT1243204B - Addotti con acido boronico di complessi di tecnezio 99m -immino- diossima - Google Patents

Addotti con acido boronico di complessi di tecnezio 99m -immino- diossima

Info

Publication number
IT1243204B
IT1243204B IT02130690A IT2130690A IT1243204B IT 1243204 B IT1243204 B IT 1243204B IT 02130690 A IT02130690 A IT 02130690A IT 2130690 A IT2130690 A IT 2130690A IT 1243204 B IT1243204 B IT 1243204B
Authority
IT
Italy
Prior art keywords
dioxy
adducts
imino
complexes
technique
Prior art date
Application number
IT02130690A
Other languages
English (en)
Other versions
IT9021306A0 (it
IT9021306A1 (it
Inventor
Karen E Linder
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT9021306A0 publication Critical patent/IT9021306A0/it
Publication of IT9021306A1 publication Critical patent/IT9021306A1/it
Application granted granted Critical
Publication of IT1243204B publication Critical patent/IT1243204B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005Compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
IT02130690A 1989-08-28 1990-08-27 Addotti con acido boronico di complessi di tecnezio 99m -immino- diossima IT1243204B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/398,880 US5069900A (en) 1989-08-28 1989-08-28 Boronic acid adducts of technetium-99m dioxime-imine complexes

Publications (3)

Publication Number Publication Date
IT9021306A0 IT9021306A0 (it) 1990-08-27
IT9021306A1 IT9021306A1 (it) 1992-02-27
IT1243204B true IT1243204B (it) 1994-05-24

Family

ID=23577176

Family Applications (1)

Application Number Title Priority Date Filing Date
IT02130690A IT1243204B (it) 1989-08-28 1990-08-27 Addotti con acido boronico di complessi di tecnezio 99m -immino- diossima

Country Status (7)

Country Link
US (1) US5069900A (it)
JP (1) JPH03148289A (it)
CA (1) CA2022579A1 (it)
DE (1) DE4026867A1 (it)
FR (1) FR2651232B1 (it)
GB (1) GB2235448B (it)
IT (1) IT1243204B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE195247T1 (de) * 1990-04-26 2000-08-15 Procter & Gamble Chelat-zubereitung, die alpha-diamin-verbindungen enthalten
CA2158249A1 (en) * 1993-03-31 1994-10-13 James W. Brodack Radiopharmaceutical formulations having non-stannous reductants
US6056941A (en) * 1999-07-28 2000-05-02 Bracco Research Usa Kit for the preparation of technetium TC 99m teboroxime myocardial perfusion agent
US8610075B2 (en) 2006-11-13 2013-12-17 Biosensors International Group Ltd. Radioimaging applications of and novel formulations of teboroxime

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4387087A (en) * 1980-04-18 1983-06-07 Research Corporation Cationic lipophilic complexes of 99m Tc and their use for myocardial and hepatobiliary imaging
US4615876A (en) * 1983-04-25 1986-10-07 Curators Of The University Of Missouri Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides
US4705849A (en) * 1985-04-15 1987-11-10 E. R. Squibb & Sons, Inc. Boronic acid adducts of technetium-99m dioxime complexes
US4795626A (en) * 1985-05-10 1989-01-03 University Of Cincinnati 99m Tc.sup.(III) myocardial imaging agents which are non-reducable in vivo
US4714605A (en) * 1986-10-14 1987-12-22 E. R. Squibb & Sons, Inc. Technetium-99m labeled dioxime complexes
US4871836A (en) * 1987-10-13 1989-10-03 E. R. Squibb & Sons, Inc. Boronic acid adducts of rhenium and radioactive isotopes of rhenium dioxime complexes

Also Published As

Publication number Publication date
CA2022579A1 (en) 1991-03-01
DE4026867A1 (de) 1991-03-28
GB9018209D0 (en) 1990-10-03
GB2235448B (en) 1993-03-17
JPH03148289A (ja) 1991-06-25
GB2235448A (en) 1991-03-06
IT9021306A0 (it) 1990-08-27
IT9021306A1 (it) 1992-02-27
US5069900A (en) 1991-12-03
FR2651232A1 (fr) 1991-03-01
FR2651232B1 (fr) 1992-05-29

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Legal Events

Date Code Title Description
0001 Granted