IT1243204B - Addotti con acido boronico di complessi di tecnezio 99m -immino- diossima - Google Patents
Addotti con acido boronico di complessi di tecnezio 99m -immino- diossimaInfo
- Publication number
- IT1243204B IT1243204B IT02130690A IT2130690A IT1243204B IT 1243204 B IT1243204 B IT 1243204B IT 02130690 A IT02130690 A IT 02130690A IT 2130690 A IT2130690 A IT 2130690A IT 1243204 B IT1243204 B IT 1243204B
- Authority
- IT
- Italy
- Prior art keywords
- dioxy
- adducts
- imino
- complexes
- technique
- Prior art date
Links
- 241000790917 Dioxys <bee> Species 0.000 title 1
- ZADPBFCGQRWHPN-UHFFFAOYSA-N boronic acid Chemical compound OBO ZADPBFCGQRWHPN-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/398,880 US5069900A (en) | 1989-08-28 | 1989-08-28 | Boronic acid adducts of technetium-99m dioxime-imine complexes |
Publications (3)
Publication Number | Publication Date |
---|---|
IT9021306A0 IT9021306A0 (it) | 1990-08-27 |
IT9021306A1 IT9021306A1 (it) | 1992-02-27 |
IT1243204B true IT1243204B (it) | 1994-05-24 |
Family
ID=23577176
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT02130690A IT1243204B (it) | 1989-08-28 | 1990-08-27 | Addotti con acido boronico di complessi di tecnezio 99m -immino- diossima |
Country Status (7)
Country | Link |
---|---|
US (1) | US5069900A (it) |
JP (1) | JPH03148289A (it) |
CA (1) | CA2022579A1 (it) |
DE (1) | DE4026867A1 (it) |
FR (1) | FR2651232B1 (it) |
GB (1) | GB2235448B (it) |
IT (1) | IT1243204B (it) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE195247T1 (de) * | 1990-04-26 | 2000-08-15 | Procter & Gamble | Chelat-zubereitung, die alpha-diamin-verbindungen enthalten |
CA2158249A1 (en) * | 1993-03-31 | 1994-10-13 | James W. Brodack | Radiopharmaceutical formulations having non-stannous reductants |
US6056941A (en) * | 1999-07-28 | 2000-05-02 | Bracco Research Usa | Kit for the preparation of technetium TC 99m teboroxime myocardial perfusion agent |
US8610075B2 (en) | 2006-11-13 | 2013-12-17 | Biosensors International Group Ltd. | Radioimaging applications of and novel formulations of teboroxime |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4387087A (en) * | 1980-04-18 | 1983-06-07 | Research Corporation | Cationic lipophilic complexes of 99m Tc and their use for myocardial and hepatobiliary imaging |
US4615876A (en) * | 1983-04-25 | 1986-10-07 | Curators Of The University Of Missouri | Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides |
US4705849A (en) * | 1985-04-15 | 1987-11-10 | E. R. Squibb & Sons, Inc. | Boronic acid adducts of technetium-99m dioxime complexes |
US4795626A (en) * | 1985-05-10 | 1989-01-03 | University Of Cincinnati | 99m Tc.sup.(III) myocardial imaging agents which are non-reducable in vivo |
US4714605A (en) * | 1986-10-14 | 1987-12-22 | E. R. Squibb & Sons, Inc. | Technetium-99m labeled dioxime complexes |
US4871836A (en) * | 1987-10-13 | 1989-10-03 | E. R. Squibb & Sons, Inc. | Boronic acid adducts of rhenium and radioactive isotopes of rhenium dioxime complexes |
-
1989
- 1989-08-28 US US07/398,880 patent/US5069900A/en not_active Expired - Lifetime
-
1990
- 1990-08-02 CA CA002022579A patent/CA2022579A1/en not_active Abandoned
- 1990-08-20 GB GB9018209A patent/GB2235448B/en not_active Expired - Fee Related
- 1990-08-20 JP JP2220935A patent/JPH03148289A/ja active Pending
- 1990-08-24 DE DE4026867A patent/DE4026867A1/de not_active Withdrawn
- 1990-08-27 IT IT02130690A patent/IT1243204B/it active IP Right Grant
- 1990-08-27 FR FR909010683A patent/FR2651232B1/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2022579A1 (en) | 1991-03-01 |
DE4026867A1 (de) | 1991-03-28 |
GB9018209D0 (en) | 1990-10-03 |
GB2235448B (en) | 1993-03-17 |
JPH03148289A (ja) | 1991-06-25 |
GB2235448A (en) | 1991-03-06 |
IT9021306A0 (it) | 1990-08-27 |
IT9021306A1 (it) | 1992-02-27 |
US5069900A (en) | 1991-12-03 |
FR2651232A1 (fr) | 1991-03-01 |
FR2651232B1 (fr) | 1992-05-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted |