IS6440A - Nýir esterar leiddir af (RR,SS)-3-(2-dímetýlamínómetýl-1-hýdroxýsýklóhexýl)fenýl 2-hýdroxýbensóati - Google Patents
Nýir esterar leiddir af (RR,SS)-3-(2-dímetýlamínómetýl-1-hýdroxýsýklóhexýl)fenýl 2-hýdroxýbensóatiInfo
- Publication number
- IS6440A IS6440A IS6440A IS6440A IS6440A IS 6440 A IS6440 A IS 6440A IS 6440 A IS6440 A IS 6440A IS 6440 A IS6440 A IS 6440A IS 6440 A IS6440 A IS 6440A
- Authority
- IS
- Iceland
- Prior art keywords
- dimethylaminomethyl
- hydroxycyclohexyl
- hydroxybenzoate
- phenyl
- esters derived
- Prior art date
Links
- 150000002148 esters Chemical class 0.000 title 1
- ZQBAKBUEJOMQEX-UHFFFAOYSA-N salicylic acid phenyl ester Natural products OC1=CC=CC=C1C(=O)OC1=CC=CC=C1 ZQBAKBUEJOMQEX-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200000060A ES2160534B1 (es) | 1999-12-30 | 1999-12-30 | Nuevos esteres derivados de (rr,ss)-2-hidroxibenzoato de 3-(2-dimetilaminometil-1-hidroxiciclohexil) fenilo. |
| PCT/ES2000/000486 WO2001049650A1 (es) | 1999-12-30 | 2000-12-26 | Nuevos esteres derivados de (rr,ss)-2-hidroxibenzoato de 3-(2-dimetilaminometil-1-hidroxiciclohexil)fenilo |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS6440A true IS6440A (is) | 2002-06-25 |
Family
ID=8491916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS6440A IS6440A (is) | 1999-12-30 | 2002-06-25 | Nýir esterar leiddir af (RR,SS)-3-(2-dímetýlamínómetýl-1-hýdroxýsýklóhexýl)fenýl 2-hýdroxýbensóati |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US6894076B2 (is) |
| EP (1) | EP1251120B1 (is) |
| JP (1) | JP2003519208A (is) |
| KR (1) | KR20020063281A (is) |
| CN (1) | CN1414946A (is) |
| AP (1) | AP1234A (is) |
| AT (1) | ATE284380T1 (is) |
| AU (1) | AU775918B2 (is) |
| BG (1) | BG106883A (is) |
| BR (1) | BR0016882A (is) |
| CA (1) | CA2395976A1 (is) |
| CZ (1) | CZ20022189A3 (is) |
| DE (1) | DE60016631D1 (is) |
| EA (1) | EA004770B1 (is) |
| EE (1) | EE200200365A (is) |
| ES (1) | ES2160534B1 (is) |
| HR (1) | HRP20020559A2 (is) |
| HU (1) | HUP0204147A3 (is) |
| IL (1) | IL150392A0 (is) |
| IS (1) | IS6440A (is) |
| MA (1) | MA26862A1 (is) |
| MX (1) | MXPA02006514A (is) |
| NO (1) | NO20023098D0 (is) |
| NZ (1) | NZ520263A (is) |
| OA (1) | OA12132A (is) |
| PL (1) | PL356056A1 (is) |
| SK (1) | SK9252002A3 (is) |
| WO (1) | WO2001049650A1 (is) |
| YU (1) | YU50902A (is) |
| ZA (1) | ZA200205193B (is) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
| NZ586792A (en) | 2008-01-25 | 2012-09-28 | Gruenenthal Chemie | Tamper resistant controlled release pharmaceutical tablets form having convex and concave surfaces |
| PT2273983T (pt) | 2008-05-09 | 2016-10-28 | Gruenenthal Gmbh | Processo para a preparação de uma formulação em pó intermediária e uma forma de dosagem sólida final sob utilização de uma etapa de congelamento por atomização |
| US8058469B2 (en) * | 2008-11-03 | 2011-11-15 | Sabic Innovative Plastics Ip B.V. | Method for making carbamates, ureas and isocyanates |
| AU2010275753B2 (en) | 2009-07-22 | 2014-08-21 | Grünenthal GmbH | Hot-melt extruded controlled release dosage form |
| SI2456424T1 (sl) | 2009-07-22 | 2013-10-30 | Gruenenthal Gmbh | Oksidacijsko stabilizirana odmerna oblika, varna pred zlorabo |
| EP2383255A1 (en) | 2010-04-28 | 2011-11-02 | Lacer, S.A. | New compounds, synthesis and use thereof in the treatment of pain |
| KR20130137627A (ko) | 2010-09-02 | 2013-12-17 | 그뤼넨탈 게엠베하 | 음이온성 중합체를 포함하는 내변조성 투여형 |
| WO2012028319A1 (en) | 2010-09-02 | 2012-03-08 | Grünenthal GmbH | Tamper resistant dosage form comprising inorganic salt |
| EP2530072A1 (en) | 2011-06-03 | 2012-12-05 | Lacer, S.A. | New compounds, synthesis and use thereof in the treatment of pain |
| US10702485B2 (en) | 2011-07-09 | 2020-07-07 | Syntrix Biosystems Inc. | Compositions and methods for overcoming resistance to tramadol |
| EP2736497B1 (en) | 2011-07-29 | 2017-08-23 | Grünenthal GmbH | Tamper-resistant tablet providing immediate drug release |
| US10201502B2 (en) | 2011-07-29 | 2019-02-12 | Gruenenthal Gmbh | Tamper-resistant tablet providing immediate drug release |
| AU2013225106B2 (en) | 2012-02-28 | 2017-11-02 | Grunenthal Gmbh | Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer |
| ES2692944T3 (es) | 2012-04-18 | 2018-12-05 | Grünenthal GmbH | Forma de dosificación farmacéutica resistente a la manipulación y resistente a la descarga rápida de la dosis |
| US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
| WO2014191397A1 (en) | 2013-05-29 | 2014-12-04 | Grünenthal GmbH | Tamper-resistant dosage form containing one or more particles |
| BR112015029616A2 (pt) | 2013-05-29 | 2017-07-25 | Gruenenthal Gmbh | forma de dosagem resistente à adulteração com perfil de liberação bimodal |
| MX368846B (es) | 2013-07-12 | 2019-10-18 | Gruenenthal Gmbh | Forma de dosificación resistente a la alteración que contiene polímero de acetato de etilen-vinilo. |
| CA2931553C (en) | 2013-11-26 | 2022-01-18 | Grunenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
| CA2947786A1 (en) | 2014-05-12 | 2015-11-19 | Grunenthal Gmbh | Tamper resistant immediate release capsule formulation comprising tapentadol |
| EP3285745A1 (en) | 2015-04-24 | 2018-02-28 | Grünenthal GmbH | Tamper-resistant dosage form with immediate release and resistance against solvent extraction |
| CA2998259A1 (en) | 2015-09-10 | 2017-03-16 | Grunenthal Gmbh | Protecting oral overdose with abuse deterrent immediate release formulations |
| RU2733373C2 (ru) | 2015-10-15 | 2020-10-01 | Цзянсу Хэнжуй Медсин Ко., Лтд. | Оксаспиропроизводное, способ его получения и его применения в лекарственных средствах |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1199764B (de) * | 1963-04-02 | 1965-09-02 | Gruenenthal Chemie | Verfahren zur Herstellung von basisch substituierten Phenolaethern |
| DE1518663A1 (de) | 1965-08-02 | 1969-12-18 | Gruenenthal Chemie | Basisch substituierte Cycloalken-derivate und Verfahren zu ihrer Herstellung |
| US3652589A (en) * | 1967-07-27 | 1972-03-28 | Gruenenthal Chemie | 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols |
| US3562589A (en) * | 1968-09-09 | 1971-02-09 | Ite Imperial Corp | Electrically resetting undervoltage trip for circuit breakers |
| US5470885A (en) * | 1993-09-29 | 1995-11-28 | The Research Foundation Of The State University Of New York | Fluorocarbons as anti-inflammatory agents |
| DE19525137C2 (de) * | 1995-07-11 | 2003-02-27 | Gruenenthal Gmbh | 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe |
| ES2141688B1 (es) * | 1998-11-06 | 2001-02-01 | Vita Invest Sa | Nuevos esteres derivados de compuestos fenil-ciclohexil sustituidos. |
| GB9924604D0 (en) * | 1999-10-18 | 1999-12-22 | European Molecular Biology Lab Embl | Genetic switch |
-
1999
- 1999-12-30 ES ES200000060A patent/ES2160534B1/es not_active Expired - Fee Related
-
2000
- 2000-12-26 AU AU20126/01A patent/AU775918B2/en not_active Ceased
- 2000-12-26 CA CA002395976A patent/CA2395976A1/en not_active Abandoned
- 2000-12-26 EE EEP200200365A patent/EE200200365A/xx unknown
- 2000-12-26 EP EP00983358A patent/EP1251120B1/en not_active Expired - Lifetime
- 2000-12-26 YU YU50902A patent/YU50902A/sh unknown
- 2000-12-26 MX MXPA02006514A patent/MXPA02006514A/es unknown
- 2000-12-26 US US10/169,177 patent/US6894076B2/en not_active Expired - Fee Related
- 2000-12-26 NZ NZ520263A patent/NZ520263A/en unknown
- 2000-12-26 IL IL15039200A patent/IL150392A0/xx unknown
- 2000-12-26 CZ CZ20022189A patent/CZ20022189A3/cs unknown
- 2000-12-26 AP APAP/P/2002/002571A patent/AP1234A/en active
- 2000-12-26 PL PL00356056A patent/PL356056A1/xx unknown
- 2000-12-26 EA EA200200614A patent/EA004770B1/ru not_active IP Right Cessation
- 2000-12-26 HU HU0204147A patent/HUP0204147A3/hu unknown
- 2000-12-26 CN CN00817916A patent/CN1414946A/zh active Pending
- 2000-12-26 KR KR1020027008500A patent/KR20020063281A/ko not_active Application Discontinuation
- 2000-12-26 WO PCT/ES2000/000486 patent/WO2001049650A1/es not_active Application Discontinuation
- 2000-12-26 JP JP2001550190A patent/JP2003519208A/ja active Pending
- 2000-12-26 DE DE60016631T patent/DE60016631D1/de not_active Expired - Fee Related
- 2000-12-26 AT AT00983358T patent/ATE284380T1/de not_active IP Right Cessation
- 2000-12-26 OA OA1200200201A patent/OA12132A/en unknown
- 2000-12-26 SK SK925-2002A patent/SK9252002A3/sk unknown
- 2000-12-26 BR BR0016882-3A patent/BR0016882A/pt not_active IP Right Cessation
-
2002
- 2002-06-24 MA MA26710A patent/MA26862A1/fr unknown
- 2002-06-25 IS IS6440A patent/IS6440A/is unknown
- 2002-06-26 NO NO20023098A patent/NO20023098D0/no not_active Application Discontinuation
- 2002-06-27 HR HR20020559A patent/HRP20020559A2/hr not_active Application Discontinuation
- 2002-06-27 ZA ZA200205193A patent/ZA200205193B/xx unknown
- 2002-06-28 BG BG106883A patent/BG106883A/xx unknown
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