IL99835A - A method of making liposomes with increased capture capacity for foreign substances to be introduced - Google Patents

A method of making liposomes with increased capture capacity for foreign substances to be introduced

Info

Publication number
IL99835A
IL99835A IL9983591A IL9983591A IL99835A IL 99835 A IL99835 A IL 99835A IL 9983591 A IL9983591 A IL 9983591A IL 9983591 A IL9983591 A IL 9983591A IL 99835 A IL99835 A IL 99835A
Authority
IL
Israel
Prior art keywords
liposomes
encapsulated
lipids
lipid
vesicles
Prior art date
Application number
IL9983591A
Other languages
English (en)
Hebrew (he)
Other versions
IL99835A0 (en
Original Assignee
Bracco Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Int Bv filed Critical Bracco Int Bv
Publication of IL99835A0 publication Critical patent/IL99835A0/xx
Publication of IL99835A publication Critical patent/IL99835A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461Dispersions, colloids, emulsions or suspensions
    • A61K49/0466Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • A61K9/1278Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL9983591A 1990-12-11 1991-10-23 A method of making liposomes with increased capture capacity for foreign substances to be introduced IL99835A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90810969 1990-12-11

Publications (2)

Publication Number Publication Date
IL99835A0 IL99835A0 (en) 1992-08-18
IL99835A true IL99835A (en) 1995-11-27

Family

ID=8205973

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9983591A IL99835A (en) 1990-12-11 1991-10-23 A method of making liposomes with increased capture capacity for foreign substances to be introduced

Country Status (20)

Country Link
US (1) US5393530A (fr)
EP (1) EP0514523B1 (fr)
JP (1) JP3241720B2 (fr)
KR (1) KR0137783B1 (fr)
AT (1) ATE131724T1 (fr)
AU (1) AU635456B2 (fr)
CA (1) CA2072559C (fr)
DE (1) DE69115682T2 (fr)
DK (1) DK0514523T3 (fr)
ES (1) ES2081605T3 (fr)
GR (1) GR3018506T3 (fr)
HU (1) HUT62458A (fr)
IE (1) IE72163B1 (fr)
IL (1) IL99835A (fr)
IN (1) IN172269B (fr)
IS (1) IS1685B (fr)
MX (1) MX9102516A (fr)
NZ (1) NZ240817A (fr)
WO (1) WO1992010166A1 (fr)
ZA (1) ZA918489B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
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US5738868A (en) * 1995-07-18 1998-04-14 Lipogenics Ltd. Liposome compositions and kits therefor

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US5874062A (en) 1991-04-05 1999-02-23 Imarx Pharmaceutical Corp. Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
WO1994008626A1 (fr) * 1992-10-16 1994-04-28 Andreas Sachse Procede et dispositif de preparation de systemes disperses liquides
US5869305A (en) * 1992-12-04 1999-02-09 The University Of Pittsburgh Recombinant viral vector system
US6217849B1 (en) 1993-09-29 2001-04-17 Bracco Research S.A. Liposome suspensions as blood pool imaging contrast agents
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WO1996025955A1 (fr) * 1995-02-24 1996-08-29 Bracco Research S.A. Suspensions de liposomes utilisees comme produit de contraste de visualisation du pool sanguin intracardiaque
US6447800B2 (en) 1996-01-18 2002-09-10 The University Of British Columbia Method of loading preformed liposomes using ethanol
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
US20010051131A1 (en) * 1996-06-19 2001-12-13 Evan C. Unger Methods for delivering bioactive agents
DE19639811A1 (de) * 1996-09-27 1998-04-02 Artur Herzog Dr Mesmer Verwendung einer Liposomenlösung zur Verstärkung der Wirksamkeit und/oder Verminderung der Toxizität von Arzneimitteln
GB9624918D0 (en) * 1996-11-29 1997-01-15 Nycomed Imaging As Particulate components
WO1998044910A1 (fr) 1997-04-09 1998-10-15 Philipp Lang NOUVELLE TECHNIQUE DE CONTROLE DE L'ADMINISTRATION DE MEDICAMENTS NON VULNERANTE $i(IN VIVO)
DE19731591C2 (de) * 1997-07-17 1999-09-16 Schering Ag Pharmazeutische Mittel enthaltend perfluoralkylgruppenhaltige Trijodaromaten und ihre Verwendung in der Tumortherapie und interventionellen Radiologie
US6306432B1 (en) * 1997-09-08 2001-10-23 Chiron Corporation High and low load formulations of IGF-I in multivesicular liposomes
US6106858A (en) * 1997-09-08 2000-08-22 Skyepharma, Inc. Modulation of drug loading in multivescular liposomes
EP2198854B1 (fr) 1997-09-18 2011-11-30 Pacira Pharmaceuticals, Inc. Compositions Anesthésiques de Liposomes à Libération Prolongée
ES2384094T3 (es) 1997-11-14 2012-06-29 Pacira Pharmaceuticals, Inc. Producción de liposomas multivesiculares
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DE19813773A1 (de) * 1998-03-27 1999-09-30 Clemens Unger Verfahren zur Herstellung von liposomalen Wirkstoffformulierungen
ATE428371T1 (de) 1998-07-17 2009-05-15 Pacira Pharmaceuticals Inc Biologisch abbaubare anordnungen zur kontrollierten freigabe eingeschlossener substanzen
US6511676B1 (en) 1999-11-05 2003-01-28 Teni Boulikas Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
AU2001266696A1 (en) 2000-06-02 2001-12-11 Bracco Research Usa Compounds for targeting endothelial cells
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CA2447990C (fr) * 2001-05-31 2012-01-31 Skyepharma Inc. Encapsulation de nanosuspensions dans des liposomes et des microspheres
JP3990880B2 (ja) * 2001-07-10 2007-10-17 キヤノン株式会社 ポリヒドロキシアルカノエート被覆リポソームの製造方法
KR100521526B1 (ko) * 2001-07-10 2005-10-13 캐논 가부시끼가이샤 폴리하이드록시알카노에이트로 이루어진 입상 구조체 및그 제조방법
US20050118250A1 (en) * 2001-11-13 2005-06-02 Paul Tardi Lipid carrier compositions with enhanced blood stability
WO2003041682A2 (fr) * 2001-11-13 2003-05-22 Celator Technologies, Inc. Compositions a vecteurs lipidiques garantissant une meilleure retention medicamenteuse
US20030129224A1 (en) * 2001-11-13 2003-07-10 Paul Tardi Lipid carrier compositions and methods for improved drug retention
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EP1547582A1 (fr) * 2003-12-23 2005-06-29 MediGene Oncology GmbH Méthode de préparation de la camptothécine carboxylate complexée avec des lipides
EP1547580A1 (fr) * 2003-12-23 2005-06-29 MediGene Oncology GmbH Chargement des nanoparticules colloidales avec un principe actif de camptothécine
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US20070031342A1 (en) * 2005-06-22 2007-02-08 Nektar Therapeutics Sustained release microparticles for pulmonary delivery
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JP5080779B2 (ja) * 2006-10-25 2012-11-21 テルモ株式会社 リポソーム製剤の製造方法
US20110059549A1 (en) * 2007-05-09 2011-03-10 Coleman Matthew A Methods and systems for producing nanolipoprotein particles
EP2224963A1 (fr) * 2007-11-19 2010-09-08 CeramOptec GmbH Composés pegylés pour la dégénérescence maculaire liée à l'âge
US8907061B2 (en) * 2008-01-11 2014-12-09 Lawrence Livermore National Security, Llc. Nanolipoprotein particles and related methods and systems for protein capture, solubilization, and/or purification
US9303273B2 (en) 2008-05-09 2016-04-05 Lawrence Livermore National Security, Llc Nanolipoprotein particles comprising a natural rubber biosynthetic enzyme complex and related products, methods and systems
WO2009143280A2 (fr) * 2008-05-22 2009-11-26 Lawrence Livermore National Security, Llc Particules de nanolipoprotéine et compositions, procédés et systèmes s'y rapportant
US9445975B2 (en) * 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
CN102202694B (zh) 2008-10-07 2014-03-12 博莱科瑞士股份有限公司 包含抗-聚合物抗体的靶向构建体和结合它们的脂质体或微泡
EP2184054A1 (fr) * 2008-11-08 2010-05-12 Lipoxen Technologies Limited Livraison ARN à faible interférence
CA2781529C (fr) 2009-09-23 2017-10-24 Indu Javeri Methodes de preparation de liposomes contenant du docetaxel
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
WO2012097346A1 (fr) 2011-01-13 2012-07-19 Variation Biotechnologies, Inc. Compositions et méthodes de traitement d'infections virales
US9644038B2 (en) 2011-12-21 2017-05-09 The Regents Of The University Of California Apolipoprotein nanodiscs with telodendrimer
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WO2013111012A2 (fr) * 2012-01-27 2013-08-01 Variation Biotechnologies, Inc. Procédés et compositions pour agents thérapeutiques
WO2015068020A2 (fr) * 2013-11-05 2015-05-14 García-Sánchez Gustavo A Traitements, formulations et procédés immunosuppresseurs
WO2015166986A1 (fr) 2014-04-30 2015-11-05 富士フイルム株式会社 Composition liposomale et procédé de production associé
JP6276847B2 (ja) * 2014-04-30 2018-02-07 富士フイルム株式会社 リポソーム組成物及びその製造方法
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JP6715265B2 (ja) 2015-05-04 2020-07-01 フェルザンティス アーゲーVersantis Ag 膜内外pH勾配ベシクルを調製する方法
US11279749B2 (en) 2015-09-11 2022-03-22 Lawrence Livermore National Security, Llc Synthetic apolipoproteins, and related compositions methods and systems for nanolipoprotein particles formation
MA43184A (fr) * 2015-11-02 2021-04-14 Fujifilm Corp Composition liposomale et son procédé de production
TWI832081B (zh) 2016-05-04 2024-02-11 美商藍瑟斯醫學影像公司 用於形成充氣微球體及成像個體之方法、震盪裝置及電腦可讀軟體
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
US11207422B2 (en) 2017-05-02 2021-12-28 Lawrence Livermore National Security, Llc MOMP telonanoparticles, and related compositions, methods and systems
CA3144443A1 (fr) * 2019-06-28 2020-12-30 Moleculin Biotech, Inc. Procede de reconstitution d'annamycine liposomale
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5738868A (en) * 1995-07-18 1998-04-14 Lipogenics Ltd. Liposome compositions and kits therefor

Also Published As

Publication number Publication date
IN172269B (fr) 1993-05-29
EP0514523A1 (fr) 1992-11-25
DE69115682D1 (de) 1996-02-01
AU9062991A (en) 1992-07-08
CA2072559C (fr) 1997-03-18
DK0514523T3 (da) 1996-01-29
AU635456B2 (en) 1993-03-18
IL99835A0 (en) 1992-08-18
EP0514523B1 (fr) 1995-12-20
ATE131724T1 (de) 1996-01-15
DE69115682T2 (de) 1996-05-15
IE72163B1 (en) 1997-03-26
ZA918489B (en) 1992-07-29
KR0137783B1 (ko) 1998-05-15
MX9102516A (es) 1992-06-01
WO1992010166A1 (fr) 1992-06-25
CA2072559A1 (fr) 1992-06-12
JPH05504150A (ja) 1993-07-01
IE914289A1 (en) 1992-06-17
IS3773A7 (is) 1992-06-12
KR920703014A (ko) 1992-12-17
NZ240817A (en) 1993-01-27
JP3241720B2 (ja) 2001-12-25
ES2081605T3 (es) 1996-03-16
IS1685B (is) 1998-02-24
US5393530A (en) 1995-02-28
GR3018506T3 (en) 1996-03-31
HUT62458A (en) 1993-05-28

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